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α-CGRP (human)

Catalog #: 3012 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
3012/1
α-CGRP (human)
1 Image
Description: CGRP agonist

Purity: ≥95%

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Biological Activity

α-CGRP (human) is an endogenous calcitonin gene-related peptide receptor (CGRP) agonist. It is a long-lasting vasodilator. α-CGRP (human) also reduces the secretion of both mouse Ins1 and Ins2 proteins and remodels amylin fibrillization in mouse pancreatic β-cells.

Technical Data

M.Wt:
3789.33
Formula:
C163H267N51O49S2
Sequence:
ACDTATCVTHRLAGLLSRSGGVVKNNFVPTNVGSKAF

(Modifications: Phe-37 = C-terminal amide, Disulfide bridge: 2-7)

Solubility:
Soluble to 0.50 mg/ml in water
Purity:
≥95%
Storage:
Store at -20°C
CAS No:
90954-53-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. International union of pharmacology XXXII. The mammalian calcitonin gene-related peptides, adrenomedullin, amylin, and calcitonin receptors.
    Poyner et al.
    Pharmacol.Revs., 2002;54:233

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