α-CGRP (human)
Purity: ≥95%
Biological Activity
α-CGRP (human) is an endogenous calcitonin gene-related peptide receptor (CGRP) agonist. It is a long-lasting vasodilator. α-CGRP (human) also reduces the secretion of both mouse Ins1 and Ins2 proteins and remodels amylin fibrillization in mouse pancreatic β-cells.Technical Data
(Modifications: Phe-37 = C-terminal amide, Disulfide bridge: 2-7)
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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International union of pharmacology XXXII. The mammalian calcitonin gene-related peptides, adrenomedullin, amylin, and calcitonin receptors.
Poyner et al.
Pharmacol.Revs., 2002;54:233
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