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AMT hydrochloride

Catalog #: 0871
5 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
0871/10
0871/50
AMT hydrochloride | CAS No. 21463-31-0 | iNOS Inhibitors
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Description: Potent, selective iNOS inhibitor

Chemical Name: 2-Amino-5,6-dihydro-6-methyl-4H-1,3-thiazine hydrochloride

Product Details
Citations (5)
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

AMT hydrochloride is a potent, selective and reversible inhibitor of iNOS (IC50 = 3.6 nM; approximately 30 and 40 times selective over nNOS and eNOS respectively).

Technical Data

M.Wt:
166.67
Formula:
C5H10N2S.HCl
Solubility:
Soluble to 10 mM in water
Storage:
Desiccate at +4°C
CAS No:
21463-31-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for AMT hydrochloride

The citations listed below are publications that use Tocris products. Selected citations for AMT hydrochloride include:

5 Citations: Showing 1 - 5

  1. Ginsenosides from Korean Red Ginseng ameliorate lung inflammatory responses: inhibition of the MAPKs/NF-κB/c-Fos pathways.
    Authors: Lee Et al.
    J Ginseng Res  2018;42:476
  2. Role of inducible nitric oxide synthase in endothelium-independent relaxation to RLX in rat aorta.
    Authors: Wong Et al.
    Br J Pharmacol  2017;174:718
  3. Inhibition of Lung Inflammation by Acanthopanax divaricatus var. Albeofructus and Its Constituents.
    Authors: Lee Et al.
    PLoS One  2016;24:67
  4. Involvement of nitric oxide in the modulation of dural arterial blood flow in the rat.
    Authors: Messlinger Et al.
    Br J Pharmacol  2000;129:1397
  5. Pharmacological and immunohistochemical evidence for a functional nitric oxide synthase system in rat peritoneal eosinophils.
    Authors: Zanardo Et al.
    Proc Natl Acad Sci U S A  1997;94:14111

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