AMTB hydrochloride

Catalog # Availability Size / Price Qty
3989/10
3989/50
AMTB hydrochloride | CAS No. 926023-82-7 | TRPM Blockers
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Description: TRPM8 blocker

Chemical Name: N-(3-Aminopropyl)-2-[(3-methylphenyl)methoxy]-N-(2-thienylmethyl)benzamide hydrochloride

Purity: ≥99%

Product Details
Citations (7)
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Biological Activity

AMTB hydrochloride is a TRPM8 channel blocker. Inhibits icilin-induced TRPM8 channel activation in a rat model (pIC50 = 6.23).

Technical Data

M.Wt:
430.99
Formula:
C23H26N2O2S.HCl
Solubility:
Soluble to 100 mM in water and to 100 mM in DMSO
Purity:
≥99%
Storage:
Desiccate at RT
CAS No:
926023-82-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. AMTB, a TRPM8 channel blocker: evidence in rats for activity in overactive bladder and painful bladder syndrome.
    Lashinger et al.
    Am.J.Physiol.Renal Physiol., 2008;295:F803

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