Arbidol
Chemical Name: Ethyl 6-Bromo-4-((dimethylamino)methyl)-5-hydroxy-1-methyl-2-((phenylthio)methyl)-1H-indole-3-carboxylate hydrochloride
Purity: ≥98%
Biological Activity
Arbidol is a broad spectrum antiviral. Displays activity against a range of respiratory and hepatitis viruses including influenza A, B and C, adenovirus, and hepatitis B and C. Increases stability of influenza viral hemagglutinins (HA) and prevents low-pH HA transition so inhibiting viral fusion. Also inhibits SARS-CoV-2 infection in vitro (IC50 = 4.11 μM).Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Arbidol: a broad-spectrum antiviral compound that blocks viral fusion.
Boriskin et al.
Curr.Med.Chem., 2008;15:997 -
The anti-influenza virus drug, arbidol is an efficient inhibitor of SARS-CoV-2 in vitro.
Wang et al.
Cell Discov., 2020;6:28
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