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Atipamezole hydrochloride

Catalog #: 2937
2 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
2937/10
2937/50
Atipamezole hydrochloride | CAS No. 104075-48-1 | Adrenergic alpha-2 Receptor Antagonists
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Description: Selective α2 antagonist

Chemical Name: 5-(2-Ethyl-2,3-dihydro-1H-indene-2-yl)-1H-imidazole hydrochloride

Purity: ≥99%

Product Details
Citations (2)
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Biological Activity

Atipamezole hydrochloride is a selective α2-adrenergic receptor antagonist (Ki values are 1.1, 1.0, 0.89, 1300 and 6500 nM for α2A, α2B, α2C, α1A and α1B receptors respectively). Brain penetrant.

Technical Data

M.Wt:
248.75
Formula:
C14H16N2.HCl
Solubility:
Soluble to 100 mM in water and to 100 mM in DMSO
Purity:
≥99%
Storage:
Desiccate at RT
CAS No:
104075-48-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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Citations for Atipamezole hydrochloride

The citations listed below are publications that use Tocris products. Selected citations for Atipamezole hydrochloride include:

2 Citations: Showing 1 - 2

  1. Dorsal BNST α2A-Adrenergic Receptors Produce HCN-Dependent Excitatory Actions That Initiate Anxiogenic Behaviors.
    Authors: Harris Et al.
    J Neurosci  2018;38:8922
  2. Endogenous analgesic action of the pontospinal noradrenergic system spatially restricts and temporally delays the progression of neuropathic pain following tibial nerve injury.
    Authors: Hughes Et al.
    Gastroenterology  2013;154:1680

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