Budesonide

Catalog #: 2671
3 Citations Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
2671/50

Budesonide | CAS No. 51333-22-3 | Glucocorticoid Receptor Compounds

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Description: Synthetic glucocorticoid; anti-inflammatory and chemopreventive

Chemical Name: (11β,16α)-16,17-[Butylidenebis(oxy)]-11,21-dihydroxypregna-1,4-diene-3,20-dione

Purity: ≥98%

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Product Details

Citations (3)

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Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

Budesonide is a synthetic anti-inflammatory glucocorticoid that displays chemopreventive activity. Prevents formation of lung adenomas and adenocarcinomas in mice following inhalation or oral administration. Reverses DNA hypomethylation and modulates expression of cancer related genes.

Technical Data

M.Wt:

430.53

Formula:

C₂₅H₃₄O₆

Solubility:

Soluble to 100 mM in DMSO and to 50 mM in ethanol

Purity:

≥98%

Storage:

Store at RT

CAS No:

51333-22-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

Budesonide. A review of its pharmacological properties and therapeutic efficacy in inflammatory bowel disease.
Spencer et al.
Drugs, 1995;50:854

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Citations for Budesonide

The citations listed below are publications that use Tocris products. Selected citations for Budesonide include:

3 Citations: Showing 1 - 3

β2-adrenoreceptor Inverse Agonist Down-regulates Muscarine Cholinergic Subtype-3 Receptor and Its Downstream Signal Pathways in Airway Smooth Muscle Cells in vitro.
Authors: Luo
Scientific Reports 2017;7:39905
Glucocorticoids Have Opposing Effects on Liver Fibrosis in Hepatic Stellate and Immune Cells.
Authors: Kim Et al.
Front Endocrinol (Lausanne) 2016;NULL:me20161029
A long-acting β2-adrenergic agonist increases the expression of muscarine cholinergic subtype-3 receptors by activating the β2-adrenoceptor cyclic adenosine monophosphate signaling pathway in airway smooth muscle cells.
Authors: Liu Et al.
Mol Endocrinol 2015;11:4121

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