Home / Histone Deacetylase Inhibitors / CHDI 00390576

CHDI 00390576

Catalog #: 6725 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
6725/5
CHDI 00390576 | CAS No. 1629729-98-1 | Histone Deacetylase Inhibitors
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Description: Potent and selective class IIa HDAC inhibitor; brain penetrant

Chemical Name: 2-(2-Fluorophenyl)-N-hydroxy-2-(4-(5-(trifluoromethyl)pyrimidin-2-yl)phenyl)acetamide

Purity: ≥98%

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Biological Activity

CHDI 00390576 is a potent and selective class IIa histone deacetylase (HDAC) inhibitor (IC50 values are 31, 50, 54 and 60 nM for HDAC7, HDAC9, HDAC4 and HDAC5, respectively). Displays >100-fold selectivity for class IIa HDACs over other HDACs. Brain penetrant.

Technical Data

M.Wt:
391.32
Formula:
C19H13F4N3O2
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
1629729-98-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold under license from CHDI Foundation

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