CP 775146
Chemical Name: 2-Methyl-2-[3-[(3S)-1-[2-[4-(1-methylethyl)phenyl]acetyl]-3-piperidinyl]phenoxy]-propanoic acid
Purity: ≥99%
Biological Activity
CP 775146 is a selective, high affinity PPARα agonist (Ki values are 24.5 nM for PPARα and >10 μM for PPARβ and PPARγ in vitro). Exhibits hypolipidemic activity in vivo.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Additional Information
Background References
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Molecular characterization of novel and selective peroxisome proliferator-activated receptor α agonists with robust hypolipidemic activity in vivo.
Kane et al.
Mol.Pharmacol., 2009;75:296
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Citation for CP 775146
The citations listed below are publications that use Tocris products. Selected citations for CP 775146 include:
1 Citation: Showing 1 - 1
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Modulators of hepatic lipoprotein metabolism identified in a search for small-molecule inducers of tribbles pseudokinase 1 expression.
Authors: Nagiec Et al.
Hum Mol Genet 2015;10:e0120295
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