Home / Dopamine D1 and D5 Receptor Agonists / CY 208-243

CY 208-243

Catalog #: 1249 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
1249/10
1249/50
CY 208-243 | CAS No. 100999-26-6 | Dopamine D1 and D5 Receptor Agonists
1 Image
Description: Selective D1-like agonist

Chemical Name: (-)-(6aR,12bR)-4,6,6a,7,8,12b-Hexahydro-7-methylindolo[4,3-a]phenanthridin

Product Details
Supplemental Products
Reviews
Biological Activity Technical Data Additional Information Background Product Datasheets Calculators

Biological Activity

CY 208-243 is a centrally active dopamine D1 receptor agonist, selective over D2 receptor sites. Stimulates adenylate cyclase in rat striatal homogenates with an EC50 of 125 nM. Unlike SKF 38393 (Cat. No. 0922), it exerts antiParkinsonian activity in animal models.

Technical Data

M.Wt:
274.36
Formula:
C19H18N2
Solubility:
Soluble to 100 mM in DMSO
Storage:
Store at RT
CAS No:
100999-26-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold with the permission of Novartis Pharma AG

Background References

  1. DA receptor agonists: selectivity and DA D1 receptor efficacy.
    Andersen and Jansen
    Eur.J.Pharmacol., 1990;188:335
  2. Antiparkinsonian activity of CY 208-243, a partial D-1 DA receptor agonist, in MPTP-treated marmosets and patients with Parkinson's disease.
    Temlett et al.
    Mov.Disord., 1989;4:261
  3. Pharmacologic properties of CY 208-243, a novel D1 agonist.
    Markstein et al.
    Progress in Catecholamine Research. Part B. Centra, 1988;:59-64

Product Datasheets

Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for CY 208-243

There are currently no reviews for this product. Be the first to review CY 208-243 and earn rewards!

Have you used CY 208-243?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.