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Eticlopride hydrochloride

Catalog #: 1847
7 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
1847/10
1847/50
Eticlopride hydrochloride | CAS No. 97612-24-3 | Non-selective Dopamine Receptor Antagonists
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Description: D2 and D3 antagonist (D3 > D2)
Alternative Names: (-)-Eticlopride

Chemical Name: 3-Chloro-5-ethyl-N-[[(2S)-1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxy-benzamide hydrochloride

Purity: ≥99%

Product Details
Citations (7)
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Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

Eticlopride hydrochloride is a selective dopamine D2/D3 receptor antagonist (Ki values are 0.50 and 0.16 nM respectively). Antipsychotic.

Technical Data

M.Wt:
377.31
Formula:
C17H25ClN2O3.HCl
Solubility:
Soluble to 100 mM in water
Purity:
≥99%
Storage:
Desiccate at RT
CAS No:
97612-24-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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Citations for Eticlopride hydrochloride

The citations listed below are publications that use Tocris products. Selected citations for Eticlopride hydrochloride include:

7 Citations: Showing 1 - 7

  1. Polysynaptic inhibition between striatal cholinergic interneurons shapes their network activity patterns in a dopamine-dependent manner.
    Authors: Dorst Et al.
    Nat Commun  2020;11:5113
  2. A DA receptor contributes to paraquat-induced neurotoxicity in Drosophila.
    Authors: Cassar Et al.
    J Ginseng Res  2015;24:197
  3. Effects of DA D2-Like Receptor Antagonists on Light Responses of Ganglion Cells in Wild-Type and P23H Rat Retinas.
    Authors: Jensen
    PLoS One  2015;10:e0146154
  4. DA in the dorsal hippocampus impairs the late consolidation of cocaine-associated memory.
    Authors: Kramar Et al.
    Int J Neuropsychopharmacol  2014;39:1645
  5. Korean Red Ginseng attenuates anxiety-like behavior during ethanol withdrawal in rats.
    Authors: Zhao Et al.
    Neuropsychopharmacology  2014;38:256
  6. Functional integration of grafted neural stem cell-derived DArgic neurons monitored by optogenetics in an in vitro Parkinson model.
    Authors: Tønnesen Et al.
    PLoS One  2011;6:e17560
  7. DArgic regulation of sleep and cataplexy in a murine model of narcolepsy.
    Authors: Burgess Et al.
    Sleep  2010;33:1295

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