Fendiline Hydrochloride

Catalog # Availability Size / Price Qty
6407/10
6407/50
Fendiline Hydrochloride | CAS No. 13636-18-5 | Ras GTPase Inhibitors
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Description: Inhibits KRas localization to the plasma membrane; also L-type calcium channel blocker

Chemical Name: N-(3,3-Diphenylpropyl)-α-methylbenzylamine hydrochloride

Purity: ≥98%

Product Details
Citations (1)
Reviews

Biological Activity

Fendiline Hydrochloride is a K-Ras inhibitor. Selectively inhibits K-Ras localization to the plasma membrane (IC50 = 9.64 μM). Blocks proliferation of cancer cell lines expressing oncogenic mutant K-Ras. Also inhibits L-type calcium channels (IC50 = 17 μM).

Technical Data

M.Wt:
351.91
Formula:
C23H25N.HCl
Solubility:
Soluble to 100 mM in DMSO and to 20 mM in ethanol
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
13636-18-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citation for Fendiline Hydrochloride

The citations listed below are publications that use Tocris products. Selected citations for Fendiline Hydrochloride include:

1 Citation: Showing 1 - 1

  1. Global feather orientations changed by electric current.
    Authors: Ting-Xin Et al.
    iScience  2021;24:102671

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