Human AGTR-1 Antibody

Catalog #: MAB102441 Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
MAB102441-100
MAB102441-SP

Detection of Human AGTR‑1 by Western Blot.

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Human AGTR-1 Antibody Summary

Species Reactivity

Human

Specificity

Detects human AGTR-1 in direct ELISAs and Western blots.

Source

Monoclonal Mouse IgG_2B Clone # 1010106

Purification

Protein A or G purified from hybridoma culture supernatant

Immunogen

Synthetic peptide containing human AGTR-1
Accession # P30556

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Label

Unconjugated

Applications

Recommended Concentration

Sample

Western Blot

1 µg/mL

See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Western Blot

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Detection of Human AGTR‑1 by Western Blot. Western blot shows lysates of human liver tissue and human lung tissue. PVDF membrane was probed with 1 µg/mL of Mouse Anti-Human AGTR-1 Monoclonal Antibody (Catalog # MAB102441) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF018). A specific band was detected for AGTR-1 at approximately 43 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: AGTR-1

Type-1 angiotensin II receptor, AGTR1, is a seven transmembrane domain (7TM) G protein-coupled receptor (GPCR) that mediates the cardiovascular effects of angiotensin II. At least four transcript variants have been described for the AGTR1 gene.

Long Name

Angiotensin II Receptor Type 1

Entrez Gene IDs

185 (Human); 11607 (Mouse); 24180 (Rat)

Alternate Names

AG2S; AGTR1; AGTR-1; AGTR1AAngiotensin II type-1 receptor; Angiostensin Receptor; angiotensin II receptor, type 1; angiotensin receptor 1; angiotensin receptor 1B; AT1; AT1AR; AT1AT1AR; AT1B; AT1BR; AT1R; AT2R1; AT2R1A; AT2R1AGTR1B; AT2R1BAT1BR; HAT1R; type-1 angiotensin II receptor; type-1B angiotensin II receptor