Human alpha -1 Adrenergic R/ADRA1A Alexa Fluor® 594-conjugated Antibody

Catalog #: FAB10298T Datasheet / COA / SDS

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FAB10298T-100UG

All alpha-1A Adrenergic R/ADRA1A Antibodies

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Human alpha -1 Adrenergic R/ADRA1A Alexa Fluor® 594-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human alpha ‑1 Adrenergic R/ADRA1A in direct ELISAs.

Source

Monoclonal Mouse IgG₁ Clone # 518508

Purification

Protein A or G purified from hybridoma culture supernatant

Immunogen

HEK293 human embryonic kidney cell line transfected with human alpha ‑1 Adrenergic R/ADRA1A
Accession # P35348

Formulation

Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Label

Alexa Fluor 594 (Excitation= 590 nm, Emission= 617 nm)

Applications

Recommended Concentration

Sample

Flow Cytometry

0.25-1 µg/10⁶ cells

HEK293 Human Cell Line Transfected with Human alpha ‑1 Adrenergic R/ADRA1A and eGFP

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Reconstitution

Reconstitution default not known

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze.

12 months from date of receipt, 2 to 8 °C as supplied.

Background: alpha-1A Adrenergic R/ADRA1A

ADRA1A (formerly known as alpha 1-C adrenergic receptor) is an alpha-adrenergic receptor which is mediated by G(q) and G(11) proteins. Alpha-1 Adrenoreceptors play an important role in mediating human prostatic smooth muscle contraction. Antagonists of ADRA1A include tamsulosin and silodosin which treat benign prostatic hyperplasia.

Long Name

Alpha-1A Adrenergic Receptor

Entrez Gene IDs

148 (Human); 1549 (Mouse); 29412 (Rat)

Alternate Names

a-1A AdrenergicR; ADRA1A; ADRA1Cadrenergic, alpha-1A-, receptor variant 1; ADRA1L1; adrenergic, alpha -1A-, receptor; adrenergic, alpha-1A-, receptor variant 3; adrenergic, alpha-1A-, receptor variant 5; adrenergic, alpha-1A-, receptor variant 8; adrenergic, alpha-1A-, receptor; adrenergic, alpha-1C-, receptor; alpha-1A Adrenergic R; alpha-1A adrenergic receptor; alpha1A AdrenergicR; Alpha-1A adrenoceptor; Alpha-1A adrenoreceptor; ALPHA1AAR; Alpha-1C adrenergic receptor; Alpha-adrenergic receptor 1c; G protein coupled receptor

Product Datasheets

Product Datasheet

COA

SDS

Product Specific Notices

This product is provided under an agreement between Life Technologies Corporation and R&D Systems, Inc, and the manufacture, use, sale or import of this product is subject to one or more US patents and corresponding non-US equivalents, owned by Life Technologies Corporation and its affiliates. The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components (1) in manufacturing; (2) to provide a service, information, or data to an unaffiliated third party for payment; (3) for therapeutic, diagnostic or prophylactic purposes; (4) to resell, sell, or otherwise transfer this product or its components to any third party, or for any other commercial purpose. Life Technologies Corporation will not assert a claim against the buyer of the infringement of the above patents based on the manufacture, use or sale of a commercial product developed in research by the buyer in which this product or its components was employed, provided that neither this product nor any of its components was used in the manufacture of such product. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, Cell Analysis Business Unit, Business Development, 29851 Willow Creek Road, Eugene, OR 97402, Tel: (541) 465-8300. Fax: (541) 335-0354.