Human AVPR2 (NP_000045) VersaClone cDNA

Catalog #: RDC0275 Datasheet / COA / SDS

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RDC0275

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Human AVPR2 (NP_000045) VersaClone cDNA Summary

Specifications

Source

N/A

Shipping Conditions

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Species

Human

Product Datasheets

Product Datasheet

COA

SDS

Background: V2 Vasopressin R/AVPR2

AVPR2 is the vasopressin receptor, type 2, also known as the V2 receptor, which belongs to the seven-transmembrane-domain G protein-coupled receptor (GPCR) superfamily, and couples to Gs thus stimulating adenylate cyclase. The subfamily that includes AVPR2 is well conserved, though several members signal via other G proteins. AVPR2 is expressed in the kidney tubule, predominantly in the distal convoluted tubule and collecting ducts, where its primary property is to respond to the pituitary hormone arginine vasopressin (AVP) by stimulating mechanisms that concentrate the urine and maintain water homeostasis in the organism. When the function of this gene is lost, the disease Nephrogenic Diabetes Insipidus (NDI) results.

Long Name

Arginine Vasopressin Receptor 2

Entrez Gene IDs

554 (Human); 12000 (Mouse); 25108 (Rat)

Alternate Names

ADHR; ADHRMGC138386; Antidiuretic hormone receptor; arginine vasopressin receptor 2; AVPR V2; AVPR2; DI1; DIR3; DIRNDI; NDI; Renal-type arginine vasopressin receptor; V2 Vasopressin R; V2 VasopressinR; V2R; V2RMGC126533; vasopressin V2 receptor