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Human CD4 APC-conjugated Antibody

Catalog #: FAB3791A
8 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
FAB3791A-100
FAB3791A-025
Detection of CD4 in Human Blood Lymphocytes by Flow Cytometry.
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Product Details
Citations (8)
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Summary Data Examples Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human CD4 APC-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects human CD4 in direct ELISAs.
Source
Monoclonal Mouse IgG2A Clone # 11830
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
Recombinant Human CD4.
Extracellular Domain
Accession # P01730
Formulation
Supplied in a saline solution containing BSA and Sodium Azide.
Label
Allophycocyanin (Excitation= 620-650 nm, Emission= 660-670 nm)

Applications

Recommended Concentration
Sample
Flow Cytometry
10 µL/106 cells
See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Flow Cytometry Detection of CD4 antibody in Human Blood Lymphocytes antibody by Flow Cytometry. View Larger

Detection of CD4 in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with (A) Mouse Anti-Human CD4 APC-conjugated Monoclonal Antibody (Catalog # FAB3791A) or (B) Mouse IgG2AAllophycocyanin Isotype Control (Catalog # IC003A) and Mouse Anti-Human CD3e CFS-conjugated Monoclonal Antibody (Catalog # FAB100F). View our protocol for Staining Membrane-associated Proteins.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.

Background: CD4

CD4 is a type I membrane glycoprotein belonging to the immunoglobulin superfamily. It is expressed predominantly on thymocytes and a subset of mature T lymphocytes. CD4 functions in collaboration with the T cell receptor in the recognition of peptide antigens that are presented by class II major histocompatibility complexes. CD4 also has been shown to be a coreceptor of HIV entry and specifically binds gp120, the external envelope glycoprotein of HIV.

Entrez Gene IDs
920 (Human); 12504 (Mouse); 24932 (Rat); 403931 (Canine); 101864991 (Cynomolgus Monkey); 493775 (Feline)
Alternate Names
CD_antigen: CD4; CD4 antigen (p55); CD4 antigen; CD4 molecule; CD4 receptor; CD4; CD4mut; T-cell surface antigen T4/Leu-3; T-cell surface glycoprotein CD4

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Citations for Human CD4 APC-conjugated Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

8 Citations: Showing 1 - 8
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  1. Phosphonate-Modified Cellulose Nanocrystals Potentiate the Th1 Polarising Capacity of Monocyte-Derived Dendritic Cells via GABA-B Receptor
    Authors: M Beki?, M Vasiljevi?, D Stojanovi?, V Kokol, D Mihajlovi?, D Vu?evi?, P Uskokovi?, M ?oli?, S Tomi?
    International Journal of Nanomedicine, 2022-07-23;17(0):3191-3216.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  2. Synergistic cytotoxic activity of cannabinoids from cannabis sativa against cutaneous T-cell lymphoma (CTCL) in-vitro and ex-vivo
    Authors: M Mazuz, A Tiroler, L Moyal, E Hodak, S Nadarajan, AC Vinayaka, B Gorovitz-H, I Lubin, A Drori, G Drori, OV Cauwenberg, A Faigenboim, D Namdar, I Amitay-Lai, H Koltai
    Oncotarget, 2020-03-31;11(13):1141-1156.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  3. IL-4 primes the dynamics of breast cancer progression via DUSP4 inhibition
    Authors: M Gaggianesi, A Turdo, A Chinnici, E Lipari, T Apuzzo, A Benfante, I Sperduti, S Di Franco, S Meraviglia, E Lo Presti, F Dieli, V Caputo, G Militello, S Vieni, G Stassi, M Todaro
    Cancer Res., 2017-04-11;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  4. Increased numbers of CD5+CD19+CD1dhighIL-10+ Bregs, CD4+Foxp3+ Tregs, CD4+CXCR5+Foxp3+ follicular regulatory T (TFR) cells in CHB or CHC patients.
    Authors: Wang L, Qiu J, Yu L, Hu X, Zhao P, Jiang Y
    J Transl Med, 2014-09-09;12(0):251.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  5. The productive entry pathway of HIV-1 in macrophages is dependent on endocytosis through lipid rafts containing CD4.
    Authors: van Wilgenburg, Bonnie, Moore, Michael, James, William, Cowley, Sally A
    PLoS ONE, 2014-01-22;9(1):e86071.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  6. CD8(+) tumor-infiltrating lymphocytes at primary sites as a possible prognostic factor of cutaneous angiosarcoma.
    Authors: Fujii H, Arakawa A, Utsumi D, Sumiyoshi S, Yamamoto Y, Kitoh A, Ono M, Matsumura Y, Kato M, Konishi K, Shiga T, Sano S, Sakaguchi S, Miyagawa-Hayashino A, Takahashi K, Uezato H, Miyachi Y, Tanioka M
    Int J Cancer, 2013-11-18;134(10):2393-402.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  7. VEGFR2 is selectively expressed by FOXP3high CD4+ Treg.
    Authors: Suzuki H, Onishi H, Wada J, Yamasaki A, Tanaka H, Nakano K, Morisaki T, Katano M
    Eur. J. Immunol., 2010-01-01;40(1):197-203.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  8. The majority of human peripheral blood CD4+CD25highFoxp3+ regulatory T cells bear functional skin-homing receptors.
    Authors: Hirahara K, Liu L, Clark RA, Yamanaka K, Fuhlbrigge RC, Kupper TS
    J. Immunol., 2006-10-01;177(7):4488-94.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry

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