Human CRHR-1 Antibody Summary
Ser24-Val415
Accession # NP_004373
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Reconstitution Calculator
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: CRHR1
Corticotrophin-Releasing Hormone Receptor 1 (CRHR-1), also known as CRFR-1, is a 7TM protein that belongs to the G protein-coupled receptor family 2. CRHR-1 is expressed in the brain and adrenal gland where it mediates corticotropin-induced effects on anxiety, depression, and stress-associated pathologies. The immunogen for this antibody corresponds to one of the four alternately spliced forms and has a 29 amino acid deletion in the first cytoplasmic domain. Human CRHR-1 shares 97% amino acid sequence identity with mouse and rat CRHR-1.
Product Datasheets
Citations for Human CRHR-1 Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Conformation-specific monoclonal antibodies recognizing the native structure of G protein-coupled receptor (GPCR)
Authors: Y Isozaki, K Tsumoto, M Tomita
International immunopharmacology, 2021-06-25;98(0):107872.
Species: Chinese Hamster
Sample Types: Whole Cells
Applications: IHC -
IGFBP2 Plays an Essential Role in Cognitive Development during Early Life
Authors: Shumsuzzaman Khan, Xinjiang Lu, Qingyao Huang, Jiawei Tang, Jian Weng, Zhi Yang et al.
Advanced Science
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