Human CTLA-4 (Research Grade Ipilimumab Biosimilar) Biotinylated Antibody

Catalog #: FAB9928B Datasheet / COA / SDS

Recombinant Monoclonal Antibody For Research Use Only

Catalog #	Availability	Size / Price	Qty
FAB9928B-100

Detection of CTLA-4 in HEK293 Human cell line Transfected with Human CTLA-4 and eGFP by Flow Cytometry.

2 Images

All CTLA-4 Antibodies

Product Details

Supplemental Products

Reviews

Summary Data Examples Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human CTLA-4 (Research Grade Ipilimumab Biosimilar) Biotinylated Antibody Summary

Species Reactivity

Human

Specificity

Detects Human CTLA-4 based on Ipilimumab therapeutic antibody.This non-therapeutic antibody uses the same variable region sequence as the therapeutic antibody Ipilimumab. This product is for research use only.

Source

Recombinant Monoclonal Human IgG₁ Clone # Hu111

Purification

Protein A or G purified from cell culture supernatant

Immunogen

Human CTLA-4

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Label

Biotin

Applications

Recommended Concentration

Sample

Flow Cytometry

10 µL/10⁶ cells

See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Flow Cytometry

View Larger

Detection of CTLA-4 in HEK293 Human cell line Transfected with Human CTLA-4 and eGFP by Flow Cytometry. HEK293 Human cell line transfected with (A) Human CTLA-4 or (B) irrelevant transfectants and eGFP was stained with Human Anti-Human CTLA-4 (Research Grade Ipilimumab Biosimilar) Biotinylated Monoclonal Antibody (Catalog # FAB9928B) followed by APC-conjugated Streptavidin (Catalog # F0050). View our protocol for Staining Membrane-associated Proteins.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Do not freeze.

12 months from date of receipt, 2 to 8 °C as supplied.

Background: CTLA-4

Ipilimumab is a biosimilar directed against the extracellular domain of CTLA‑4. This product can be used flow cytometry or various assay formats to measure CTLA‑4 expression.

Long Name

Cytotoxic T-lymphocyte-associated Molecule 4

Entrez Gene IDs

1493 (Human); 12477 (Mouse); 403696 (Canine); 102115124 (Cynomolgus Monkey)

Alternate Names

CD; CD152 antigen; CD152; CD152IDDM12; CD28; celiac disease 3; CELIAC3; CTLA4; CTLA-4; cytotoxic T-lymphocyte antigen 4; cytotoxic T-lymphocyte protein 4; Cytotoxic T-lymphocyte-associated antigen 4; cytotoxic T-lymphocyte-associated protein 4; cytotoxic T-lymphocyte-associated serine esterase-4; GRD4; GSE; ICOS; ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4