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Human ERR beta/NR3A2 Antibody

Catalog #: PP-H6707-00
4 Citations Datasheet / COA / SDS
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PP-H6707-00
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Citations (4)
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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human ERR beta/NR3A2 Antibody Summary

Species Reactivity
Human
Source
Monoclonal Mouse IgG2a Clone # H6707
Formulation
A liquid formulation in physiologic saline with 0.1% NaN3.
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Preparation and Storage

Shipping
The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: ERR beta/NR3B2

Estrogen-related receptor alpha (ERR-alpha, ERR1, ESRL1; NR3B1) is a member of the orphan nuclear receptor family. ERR-alpha is expressed in the liver, kidney, brain, heart, uterus, vagina and cervix. ERR-alpha takes part in the cell cycle and the fatty acid metabolizing of the musculus skeleti. ERR-alpha was shown to interact with ER-alpha. ERR-beta (ERR2; NR3B2) is also expressed in the liver, brain, uterus, vagina, and cervix. ERR-beta has a role in early placental development. ERR-gamma (ESRRG; NR3B3) is expressed in the brain, kidney, testis, lung, adrenal gland, pancreas, placenta and bone marrow. ERR-gamma was shown to be located in the critical region for Usher's syndrome.

Long Name
Estrogen-related Receptor beta
Entrez Gene IDs
2103 (Human)
Alternate Names
ERR beta; ERR2; ESRL2; ESRRB; estrogen-related receptor beta; NR3B2

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Citations for Human ERR beta/NR3A2 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

4 Citations: Showing 1 - 4
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  1. BAP1/ASXL complex modulation regulates epithelial-mesenchymal transition during trophoblast differentiation and invasion
    Authors: V Perez-Garc, G Lea, P Lopez-Jime, H Okkenhaug, GJ Burton, A Moffett, MY Turco, M Hemberger
    Elife, 2021-06-25;10(0):.
    Species: Human
    Sample Types: Cell Lysates, Whole Cells
    Applications: IHC, Western Blot
  2. Ncoa3 functions as an essential Esrrb coactivator to sustain embryonic stem cell self-renewal and reprogramming.
    Authors: Percharde M, Lavial F, Ng J, Kumar V, Tomaz R, Martin N, Yeo J, Gil J, Prabhakar S, Ng H, Parker M, Azuara V
    Genes Dev, 2012-09-26;26(20):2286-98.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: ChIP, Western Blot
  3. Estrogen-related receptor beta interacts with Oct4 to positively regulate Nanog gene expression.
    Authors: van den Berg DL, Zhang W, Yates A, Engelen E, Takacs K, Bezstarosti K, Demmers J, Chambers I, Poot RA
    Mol. Cell. Biol., 2008-07-28;28(19):5986-95.
    Species: Human
    Sample Types: Cell Lysates
    Applications: ChIP, Immunoprecipitation
  4. Orphan nuclear receptor estrogen-related receptor-beta suppresses in vitro and in vivo growth of prostate cancer cells via p21(WAF1/CIP1) induction and as a potential therapeutic target in prostate cancer.
    Authors: Yu S, Wong YC, Wang XH, Ling MT, Ng CF, Chen S, Chan FL
    Oncogene, 2007-12-10;27(23):3313-28.
    Species: Human
    Sample Types: Cell Lysates, Whole Tissue
    Applications: ChIP, IHC-P, Western Blot

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