Human KCC4/SLC12A7 (NP_006589) VersaClone cDNA

Catalog # Availability Size / Price Qty
RDC0487
R&D Systems VersaClone cDNA Plasmids
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Human KCC4/SLC12A7 (NP_006589) VersaClone cDNA Summary

Specifications

Source
N/A
Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Species
Human

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Background: KCC4/SLC12A7

Cation chloride cotransporters, including the potassium-chloride cotransporters (KCCs), are involved in the electroneutral movement of ions across the plasma membrane. SLC12A7 contains 12 membrane-spanning segments, 8 phosphorylation sites, 7 of which are in the C terminus, and 4 potential N-glycosylation sites. It is important for potassium recycling by siphoning potassium ions after their exit from outer hair cells into supporting Deiters cells, where potassium enters the gap junction pathway.

Long Name
Potassium/Chloride Transporter KCC4
Entrez Gene IDs
10723 (Human); 20499 (Mouse); 308069 (Rat)
Alternate Names
DKFZp434F076; KCC4; KCC4Electroneutral potassium-chloride cotransporter 4; K-Cl cotransporter 4; potassium/chloride transporter KCC4; SLC12A7; solute carrier family 12 (potassium/chloride transporters), member 7; solute carrier family 12 member 7

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