Human NRG1 Isoform GGF2 Antibody

Catalog #: AF2015
1 Citation Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
AF2015
AF2015-SP

Product Details

Citations (1)

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human NRG1 Isoform GGF2 Antibody Summary

Species Reactivity

Human

Specificity

Detects human NRG1 Isoform GGF2 in direct ELISAs and Western blots. In direct ELISAs, less than 1% cross‑reactivity with recombinant human (rh) NRG‑1 alpha EGF domain, rhNRG1-beta 1 extracellular domain, rhNRG1-beta 1 EGF domain, rhSMDF, and recombinant mouse NRG3 is observed.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

E. coli-derived recombinant human NRG1 Isoform GGF2
Gly51-Cys248
Accession # NP_039256

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Purity

Immunogen affinity purified

Applications

Recommended Concentration

Sample

Western Blot

0.1 µg/mL

Recombinant Human NRG1 Isoform GGF2

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Neuregulin-1 Isoform GGF2

By alternative splicing, the Neuregulin 1 gene ecodes at least 10 secreted or membrane-bound proteins, all of which contain an EGF-like domain. Neuregulin 1 isoforms bind and signal via the ErbB family of receptor tyrosine kinases. Isoform GGF2 contains a unique kringle-like domain, plus Ig and EGF-like domains that are also present in multiple Neuregulin 1 isoforms.

Entrez Gene IDs

3084 (Human); 211323 (Mouse); 112400 (Rat)

Alternate Names

GGF2; ARIA; GGF; GGF2; HGL; HRG; HRG1; HRGA; MST131; MSTP131; NDF; Neuregulin1 Isoform GGF2; Neuregulin-1 Isoform GGF2; NRG1-IT2; SMDF

Product Datasheets

Product Datasheet

COA

SDS

Related Research Areas

Citation for Human NRG1 Isoform GGF2 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1