Human PI 3-Kinase p110 beta Antibody Summary
Met152-Val349
Accession # P42338
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Scientific Data
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Detection of Human PI 3-Kinase p110 beta by Western Blot. Western blot shows lysates of A431 human epithelial carcinoma cell line and Jurkat human acute T cell leukemia cell line. PVDF membrane was probed with 1 µg/mL of Human PI 3-Kinase p110 beta Monoclonal Antibody (Catalog # MAB2686) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF007). A specific band was detected for PI 3-Kinase p110 beta at approximately 110 kDa (as indicated). This experiment was conducted using Immunoblot Buffer Group 1.
Reconstitution Calculator
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: PI 3-Kinase p110 beta
Class IA phosphoinositide 3-kinases (PI 3-kinases) are a family of p85/p110 heterodimeric lipid kinases that function as signal transducers downstream of growth factor receptors, mainly receptor tyrosine kinases. Mammals express three class IA catalytic subunits: p110 alpha, p110 beta, and p110δ. Reports suggest that the p110 beta subunit may have special importance in promoting cell proliferation.
Product Datasheets
Citations for Human PI 3-Kinase p110 beta Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 3
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Bacterial Antigens Reduced the Inhibition Effect of Capsaicin on Cal 27 Oral Cancer Cell Proliferation
Authors: R Chakrabort, K Vickery, C Darido, S Ranganatha, H Hu
International Journal of Molecular Sciences, 2021-08-12;22(16):.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
The PI3K subunits, P110&alpha and P110&beta are potential targets for overcoming P-gp and BCRP-mediated MDR in cancer
Authors: L Zhang, Y Li, Q Wang, Z Chen, X Li, Z Wu, C Hu, D Liao, W Zhang, ZS Chen
Mol. Cancer, 2020-01-17;19(1):10.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Nuclear factor-kappaB decoy oligodeoxynucleotides ameliorate impaired glucose tolerance and insulin resistance in mice with cecal ligation and puncture-induced sepsis.
Authors: Matsuda N, Yamamoto S, Yokoo H, Tobe K, Hattori Y
Crit. Care Med., 2009-10-01;37(10):2791-9.
Species: Mouse
Sample Types: Tissue Homogenates
Applications: Western Blot
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Antibody was printed on custom arrays and incubated with fluorescently labeled human EDTA plasma
