Home / PRG-1/LPPR4 / Human PRG-1/LPPR4 Antibody

Human PRG-1/LPPR4 Antibody

Catalog #: MAB2874
1 Citation Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
MAB2874
MAB2874-SP
Product Details
Citations (1)
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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human PRG-1/LPPR4 Antibody Summary

Species Reactivity
Human
Specificity
Detects PRG‑1/LPPR4 in direct ELISAs and Western blots.
Source
Monoclonal Mouse IgG2B Clone # 368701
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
E. coli-derived recombinant human PRG‑1/LPPR4
Ser285-Asp715
Accession # AAO85400
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Purity
Protein A or G purified from hybridoma culture supernatant

Applications

Recommended Concentration
Sample
Western Blot
1 µg/mL
Recombinant Human PRG‑1/LPPR4

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS.
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Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: PRG-1/LPPR4

PRG-1 (plasticity-related gene-1) is a member of the lipid phosphate phosphatase-related protein (LPR) family. The 715 aa protein has a calculated (unglycosylated) molecular weight of 78 kDa. LPR members have six N-terminal transmembrane sequences and a C-terminal cytoplasmic domain thought to regulate phospholipid phosphatase activity. PRG-1 is expressed on axons in the hippocampus and is upregulated during axonal outgrowth. The C-terminal domain of human PRG-1 (amino acids 285‑715) shares 95% and 94% amino acid identity with mouse and rat PRG-1, respectively.

Long Name
Plasticity Related Gene 1/Lipid Phosphate Phosphatase-related Protein Type 4
Entrez Gene IDs
9890 (Human)
Alternate Names
LPPR4 lipid phosphate phosphatase-related protein type 4; LPPR4; LPR4; PHP1; PRG1; PRG-1; RP4-788L13.1

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Citation for Human PRG-1/LPPR4 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

  1. The Axonal Membrane Protein PRG2 Inhibits PTEN and Directs Growth to Branches
    Authors: A Brosig, J Fuchs, F Ipek, C Kroon, S Schrötter, M Vadhvani, A Polyzou, J Ledderose, M van Diepen, HG Holzhütter, T Trimbuch, N Gimber, J Schmoranze, I Lieberam, C Rosenmund, C Spahn, P Scheerer, M Szczepek, G Leondariti, BJ Eickholt
    Cell Rep, 2019-11-12;29(7):2028-2040.e8.
    Species: Rat
    Sample Types: Tissue Lysate
    Applications: Western Blot

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