Human SOX7 Antibody

Catalog #: AF2766
9 Citations Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
AF2766
AF2766-SP

All SOX7 Antibodies

Product Details

Citations (9)

Supplemental Products

Reviews

Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human SOX7 Antibody Summary

Species Reactivity

Human

Specificity

Detects human SOX7 in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 2% cross-reactivity with recombinant human SOX1, -2, -3, -9, -10, and -17 is observed.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

E. coli-derived recombinant human SOX7
Ser249-Ala345
Accession # Q9BT81

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Label

Unconjugated

Applications

Recommended Concentration

Sample

Western Blot

0.1 µg/mL

Recombinant Human SOX7

Immunohistochemistry

5-15 µg/mL

Immersion fixed paraffin-embedded sections of human breast and lung

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: SOX7

SOX7 belongs to the Sox (SRY-like HMG-box gene) family of transcription factors with diverse roles in development. SOX7 has been suggested to play a crucial role in parietal endoderm differentiation. SOX7 is expressed in many embryonic and adult tissues.

Long Name

Transcription Factor SOX7

Entrez Gene IDs

83595 (Human)

Alternate Names

MGC10895; SOX7 transcription factor; SOX7; SRY (sex determining region Y)-box 7; transcription factor SOX-7

Product Datasheets

Product Datasheet

COA

SDS

Related Research Areas

Citations for Human SOX7 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

9 Citations: Showing 1 - 9
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The transcription factor Sox7 modulates endocardiac cushion formation contributed to atrioventricular septal defect through Wnt4/Bmp2 signaling
Authors: N Hong, E Zhang, H Xie, L Jin, Q Zhang, Y Lu, AF Chen, Y Yu, B Zhou, S Chen, Y Yu, K Sun
Cell Death & Disease, 2021-04-12;12(4):393.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry, ICC
Comprehensive transcriptomic profiling reveals SOX7 as an early regulator of angiogenesis in hypoxic human endothelial cells
Authors: J Klomp, J Hyun, J Klomp, K Pajcini, J Rehman, AB Malik
J. Biol. Chem., 2020-02-18;0(0):.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot
Sox7 promotes high-grade glioma by increasing VEGFR2-mediated vascular abnormality
Authors: IK Kim, K Kim, E Lee, DS Oh, CS Park, S Park, JM Yang, JH Kim, HS Kim, DT Shima, JH Kim, SH Hong, YH Cho, YH Kim, JB Park, GY Koh, YS Ju, HK Lee, S Lee, I Kim
J. Exp. Med., 2018-02-14;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: IHC-P
SOX7 expression is critically required in FLK1-expressing cells for vasculogenesis and angiogenesis during mouse embryonic development
Authors: AJ Lilly, A Mazan, DA Scott, G Lacaud, V Kouskoff
Mech. Dev., 2017-05-31;0(0):.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC
Efficient derivation of extraembryonic endoderm stem cell lines from mouse postimplantation embryos
Sci Rep, 2016-12-19;6(0):39457.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC
Sox7, Sox17, and Sox18 Cooperatively Regulate Vascular Development in the Mouse Retina.
Authors: Zhou Y, Williams J, Smallwood P, Nathans J
PLoS ONE, 2015-12-02;10(12):e0143650.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC-Fr
Sox7 is regulated by ETV2 during cardiovascular development.
Authors: Behrens, Ann N, Zierold, Claudia, Shi, Xiaozhon, Ren, Yi, Koyano-Nakagawa, Naoko, Garry, Daniel J, Martin, Cindy M
Stem Cells Dev, 2014-06-17;23(17):2004-13.
Species: Human
Sample Types: Cell Culture Supernates
Applications: Western Blot
A role for PDGF signaling in expansion of the extra-embryonic endoderm lineage of the mouse blastocyst.
Authors: Artus J, Panthier JJ, Hadjantonakis AK
Development, 2010-09-08;137(20):3361-72.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC
Short-term BMP-4 treatment initiates mesoderm induction in human embryonic stem cells.
Authors: Zhang P, Li J, Tan Z, Wang C, Liu T, Chen L, Yong J, Jiang W, Sun X, DU L, Ding M, Deng H
Blood, 2007-11-27;111(4):1933-41.
Species: Human
Sample Types: Whole Cells
Applications: ICC