Home / delta Opioid Receptor Antagonists / ICI 174,864

ICI 174,864

Catalog #: 0820
5 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
0820/1
ICI 174,864
1 Image
Description: δ selective peptide antagonist

Purity: ≥95%

Product Details
Citations (5)
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Biological Activity

ICI 174,864 is a selective δ opioid antagonist. Exhibits partial agonist in vitro activity at δ receptors at high concentrations.

Technical Data

M.Wt:
691.87
Formula:
C38H53N5O7
Sequence:
YXXFL

(Modifications: Tyr-1 = N,N-diallyl-Tyr, X = Aib)

Solubility:
Soluble to 69.19 mg/ml in DMSO and to 1 mg/ml in water
Purity:
≥95%
Storage:
Store at -20°C
CAS No:
89352-67-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold with the permission of AstraZeneca UK Ltd.

Product Datasheets

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Citations for ICI 174,864

The citations listed below are publications that use Tocris products. Selected citations for ICI 174,864 include:

5 Citations: Showing 1 - 5

  1. Synapse-specific opioid modulation of thalamo-cortico-striatal circuits.
    Authors: Birdsong Et al.
    Elife  2019;8
  2. Input-Timing-Dependent Plasticity in the Hippocampal CA2 Region and Its Potential Role in Social Memory.
    Authors: Leroy Et al.
    Neuron  2017;95:1089
  3. Opioid and progesterone signaling is obligatory for early human embryogenesis.
    Authors: Gallego Et al.
    J Neurophysiol  2009;18:737
  4. N-glycan-mediated quality control in the endoplasmic reticulum is required for the expression of correctly folded delta-opioid receptors at the cell surface.
    Authors: Markkanen and Petäjä-Repo
    J Biol Chem  2008;283:29086
  5. Constitutive activity of the delta-opioid receptor expressed in C6 glioma cells: identification of non-peptide delta-inverse agonists.
    Authors: Neilan Et al.
    Br J Pharmacol  1999;128:556

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