Laurdan
Chemical Name: 1-[6-(Dimethylamino)-2-naphthalenyl]-1-dodecanone
Purity: ≥95%
Biological Activity
Laurdan is a polarity sensitive fluorescent probe for imaging lipid rafts in membranes (also known as lipid microdomains). It is suitable for use with generalized polarization (GP) imaging and scanning fluorescence correlation spectroscopy (FCS). Laurdan can be used to image lipids in live and fixed cells as well as in whole tissues with multiphoton microscopy. Laurdan has emission maxima of 440 nm and 490 nm in gel and liquid phase membranes, respectively.Optical Data for Laurdan
| λabs | 366 nm |
|---|---|
| λem | 497 nm |
| Extinction Coefficient (ε) | 19500 M-1cm-1 |
| Quantum Yield (φ) | 0.61 |
| Application | Polarity sensitive fluorescent probe for lipid raft and cell membrane investigations |
| Alternative For | C-Laurdan, Di-4-ANEPPDHQ |
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Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
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