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m-3M3FBS

Catalog #: 1941
7 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
1941/10
m-3M3FBS | CAS No. 200933-14-8 | Phospholipase Activators
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Description: Phospholipase C activator

Chemical Name: 2,4,6-Trimethyl-N-[3-(trifluoromethyl)phenyl]benzenesulfonamide

Purity: ≥99%

Product Details
Citations (7)
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Biological Activity Technical Data Additional Information Background Product Datasheets Calculators

Biological Activity

m-3M3FBS is an activator of phospholipase C (PLC). Stimulates superoxide generation, Ca2+ release and inositol phosphate formation in a variety of cell types. Also inhibits growth of the leukemic cell lines U937 and THP-1.

Negative Control also available.

Technical Data

M.Wt:
343.36
Formula:
C16H16F3NO2S
Solubility:
Soluble to 100 mM in ethanol and to 100 mM in DMSO
Purity:
≥99%
Storage:
Store at RT
CAS No:
200933-14-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Other Product-Specific Information:

Product Datasheets

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Citations for m-3M3FBS

The citations listed below are publications that use Tocris products. Selected citations for m-3M3FBS include:

7 Citations: Showing 1 - 7

  1. IPIP27 Coordinates PtdIns(4,5)P2 Homeostasis for Successful Cytokinesis.
    Authors: Carim Et al.
    Curr Biol  2019;29:775
  2. TMEM203 Is a Novel Regulator of Intracellular Calcium Homeostasis and Is Required for Spermatogenesis.
    Authors: Shambharkar Et al.
    PLoS One  2015;10:e0127480
  3. DA Promotes Motor Cortex Plasticity and Motor Skill Learning via PLC Activation.
    Authors: Rioult-Pedotti Et al.
    J Gen Physiol  2015;10:e0124986
  4. Activation of phospholipase C mimics the phase shifting effects of light on melatonin rhythms in retinal photoreceptors.
    Authors: Semple-Rowland Et al.
    PLoS One  2014;8:e83378
  5. Calcium release-dependent actin flow in the leading process mediates axophilic migration.
    Authors: Hutchins Et al.
    PLoS One  2013;33:11361
  6. High extracellular Ca2+ stimulates Ca2+-activated Cl- currents in frog parathyroid cells through the mediation of arachidonic acid cascade.
    Authors: Okada Et al.
    PLoS One  2011;6:e19158
  7. Phospholipase C activator m-3M3FBS affects Ca2+ homeostasis independently of phospholipase C activation.
    Authors: Krjukova Et al.
    Br J Pharmacol  2004;143:3

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