m-Chlorophenylbiguanide hydrochloride

Catalog #: 0440
4 Citations Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
0440/100

m-Chlorophenylbiguanide hydrochloride | CAS No. 2113-05-5 | 5-HT3 Receptor Agonists

1 Image

Description: Potent and selective 5-HT3 agonist

Chemical Name: 1-(3-Chlorophenyl)biguanide hydrochloride

Purity: ≥98%

View All Products for 5-HT3 Receptor Agonists

Product Details

Citations (4)

Supplemental Products

Reviews

Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

m-Chlorophenylbiguanide hydrochloride is a prototypical potent and selective 5-HT₃ receptor agonist.

Technical Data

M.Wt:

248.11

Formula:

C₈H₁₀ClN₅.HCl

Solubility:

Soluble to 100 mM in water

Purity:

≥98%

Storage:

Desiccate at RT

CAS No:

2113-05-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

5HT₃ receptors in NG108-15 neuroblastoma X glioma cells: effect of the novel agonist 1-(m-chlorophenyl)biguanide.
Boess et al.
Neuropharmacology, 1992;31:561
1-(m-Chlorophenyl)biguanide, a potent high affinity 5-HT₃ receptor agonist.
Kilpatrick et al.
Eur.J.Pharmacol., 1990;182:193
The agonist properties of m-chlorophenylbiguanide and 2-methyl-5-hydroxytryptamine on 5-HT₃ receptors in N1E-115 neuroblastoma cells.
Sepulveda et al.
Br.J.Pharmacol., 1991;104:536
Different efficacy of specific agonists at 5-HT₃ receptor splice variants: the role of the extra six amino acid segment.
Niemeyer and Lummis
Br.J.Pharmacol., 1998;123:661

Product Datasheets

COA view current batch

Or select another batch:

View Batch

SDS

Reconstitution Calculator

Molarity Calculator

Reconstitution Calculator

Molarity Calculator

Mass

Concentration

Volume

M. Wt* g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Citations for m-Chlorophenylbiguanide hydrochloride

The citations listed below are publications that use Tocris products. Selected citations for m-Chlorophenylbiguanide hydrochloride include:

4 Citations: Showing 1 - 4

Vort. disinhibits pyramidal cell function and enhances synaptic plasticity in the rat hippocampus.
Authors: Dale Et al.
J Psychopharmacol 2014;28:891
First and second generation antipsychotics influence hippocampal gamma oscillations by interactions with 5-HT3 and D3 receptors.
Authors: Schulz Et al.
Br J Pharmacol 2012;167:1480
Autocrine and paracrine roles for ATP and serotonin in mouse taste buds.
Authors: Huang Et al.
PLoS One 2009;29:13909
Serotonin modifies cytoskeleton and brush-border membrane architecture in human intestinal epithelial cells.
Authors: Gill Et al.
Am J Physiol Gastrointest Liver Physiol 2008;295:G700

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for m-Chlorophenylbiguanide hydrochloride

There are currently no reviews for this product. Be the first to review m-Chlorophenylbiguanide hydrochloride and earn rewards!

Have you used m-Chlorophenylbiguanide hydrochloride?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.