Home / Group I mGluR Modulators / ML 337

ML 337

Catalog #: 4982 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
4982/10
4982/50
ML 337 | CAS No. 1443118-44-2 | Group I mGluR Modulators
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Description: Selective negative allosteric modulator of mGlu3 receptors

Chemical Name: [2-Fluoro-4-[2-(4-methoxyphenyl)ethynyl]phenyl][(3R)-3-hydroxy-1-piperidinyl]methanone

Purity: ≥98%

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Biological Activity

ML 337 is a selective negative allosteric modulator of mGlu3 (IC50 = 593 nM). Displays no activity at mGlu1, mGlu2 or mGlu4-8 at concentrations up to 30 μM. Brain penetrant.

Technical Data

M.Wt:
353.39
Formula:
C21H20FNO3
Solubility:
Soluble to 100 mM in DMSO and to 20 mM in ethanol
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
1443118-44-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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