Mouse CCL3/MIP-1 alpha Quantikine ELISA Kit Summary
Product Summary
Precision
Cell Culture Supernates, Serum
Intra-Assay Precision | Inter-Assay Precision | |||||
---|---|---|---|---|---|---|
Sample | 1 | 2 | 3 | 1 | 2 | 3 |
n | 20 | 20 | 20 | 20 | 20 | 20 |
Mean (pg/mL) | 13.7 | 86 | 184 | 13.8 | 83 | 179 |
Standard Deviation | 0.6 | 3.1 | 5 | 0.9 | 5.2 | 12 |
CV% | 4.4 | 3.6 | 2.7 | 6.5 | 6.3 | 6.7 |
Recovery
The recovery of mouse MIP-1 alpha spiked to three levels throughout the range of the assay in various matrices was evaluated.
Sample Type | Average % Recovery | Range % |
---|---|---|
Cell Culture Supernates (n=5) | 105 | 95-114 |
Serum (n=9) | 97 | 85-108 |
Linearity
Scientific Data
Preparation and Storage
Background: CCL3/MIP-1 alpha
MIP-1 alpha (macrophage inflammatory protein 1 alpha) is a member of the CC or beta chemokine subfamily that was originally purified from the conditioned media of an LPS-stimulated murine macrophage cell line. MIP-1 alpha acts as a chemoattractant to a variety of cells including monocytes, T cells, B cells and eosinophils.
The two human MIP-1 alpha genes arise by duplication/mutation. They code for MIP-1 alpha isoforms CCL3/LD78a and CCL3L1/LD78b, which share 94% amino acid sequence homology. Whereas the human CCL3/LD78a is a single-copy gene, the human CCL3L1/LD78b gene copy number varies within the population. Human CCL3L1/LD78b binds and signals through chemokine receptors CCR1, CCR5. When compared to CCL3/LD78a, CCL3L1/LD78b has higher binding affinity to CCR5, which also functions as a coreceptor for HIV-1 entry. The copy number of CCL3L1 is one of several genetic determinants of HIV-1 susceptibility.
Assay Procedure
Refer to the product- Prepare all reagents, standard dilutions, and samples as directed in the product insert.
- Remove excess microplate strips from the plate frame, return them to the foil pouch containing the desiccant pack, and reseal.
- Add 50 µL of Assay Diluent to each well.
- Add 50 µL of Standard, Control, or sample to each well. Cover with a plate sealer, and incubate at room temperature for 2 hours.
- Aspirate each well and wash, repeating the process 4 times for a total of 5 washes.
- Add 100 µL of Conjugate to each well. Cover with a new plate sealer, and incubate at room temperature for 2 hours.
- Aspirate and wash 5 times.
- Add 100 µL Substrate Solution to each well. Incubate at room temperature for 30 minutes. PROTECT FROM LIGHT.
- Add 100 µL of Stop Solution to each well. Read at 450 nm within 30 minutes. Set wavelength correction to 540 nm or 570 nm.
Citations for Mouse CCL3/MIP-1 alpha Quantikine ELISA Kit
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 10
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Tubule-mitophagic secretion of SerpinG1 reprograms macrophages to instruct anti-septic acute kidney injury efficacy of high-dose ascorbate mediated by NRF2 transactivation
Authors: Y Ni, GH Wu, JJ Cai, R Zhang, Y Zheng, JQ Liu, XH Yang, X Yang, Y Shen, JM Lai, XM Ye, SJ Mo
International journal of biological sciences, 2022-08-08;18(13):5168-5184.
Species: Mouse
Sample Types: Cell Culture Supernates
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A CCR5 antagonist, maraviroc, alleviates neural circuit dysfunction and behavioral disorders induced by prenatal valproate exposure
Authors: Y Ishihara, T Honda, N Ishihara, K Namba, M Taketoshi, Y Tominaga, M Tsuji, CFA Vogel, T Yamazaki, K Itoh, T Tominaga
Journal of Neuroinflammation, 2022-07-29;19(1):195.
Species: Mouse
Sample Types: Tissue Homogenates
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Neutrophil-dendritic cell interaction plays an important role in live attenuated Leishmania vaccine induced immunity
Authors: P Bhattachar, N Ismail, A Saxena, S Gannavaram, R Dey, T Oljuskin, A Akue, K Takeda, J Yu, S Karmakar, PK Dagur, JP McCoy, HL Nakhasi
PloS Neglected Tropical Diseases, 2022-02-22;16(2):e0010224.
Species: Mouse
Sample Types: Cell Culture Supernates
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Brain-specific TRAF7 deletion ameliorates traumatic brain injury by suppressing MEKK3-regulated glial inflammation and neuronal death
Authors: Y Yuxiong, X Xujin, T Yi, C Ya, L Yujuan, H Shanshan, W Huiwen
International immunopharmacology, 2021-12-23;103(0):108219.
Species: Transgenic Mouse
Sample Types: Tissue Homogenates
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A New Mouse Model of Chronic Myocarditis Induced by Recombinant Bacille Calmette-Gu�rin Expressing a T-Cell Epitope of Cardiac Myosin Heavy Chain-&alpha
Authors: K Tajiri, K Imanaka-Yo, Y Tsujimura, K Matsuo, M Hiroe, K Aonuma, M Ieda, Y Yasutomi
International Journal of Molecular Sciences, 2021-01-14;22(2):.
Species: Mouse
Sample Types: Tissue Homogenates
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Infusion of blood from mice displaying cerebral amyloidosis accelerates amyloid pathology in animal models of Alzheimer's disease
Authors: R Morales, C Duran-Anio, J Bravo-Aleg, LD Estrada, M Shahnawaz, PP Hu, C Kramm, D Morales-Sc, A Urayama, C Soto
Acta neuropathologica communications, 2020-12-07;8(1):213.
Species: Mouse
Sample Types: Cell Culture Supernates
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Impaired RIPK1 ubiquitination sensitizes mice to TNF toxicity and inflammatory cell death
Authors: M Kist, LG K?m?ves, T Goncharov, DL Dugger, C Yu, M Roose-Girm, K Newton, JD Webster, D Vucic
Cell Death Differ, 2020-09-30;0(0):.
Species: Mouse
Sample Types: Serum
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Tofacitinib enhances delivery of antibody-based therapeutics to tumor cells through modulation of inflammatory cells
Authors: N Simon, A Antignani, SM Hewitt, M Gadina, C Alewine, D FitzGerald
JCI Insight, 2019-03-07;0(0):.
Species: Mouse
Sample Types: Serum
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Inhibition of avian-origin influenza A(H7N9) virus by the novel cap-dependent endonuclease inhibitor baloxavir marboxil
Authors: K Taniguchi, Y Ando, H Nobori, S Toba, T Noshi, M Kobayashi, M Kawai, R Yoshida, A Sato, T Shishido, A Naito, K Matsuno, M Okamatsu, Y Sakoda, H Kida
Sci Rep, 2019-03-05;9(1):3466.
Species: Mouse
Sample Types: Tissue Homogenates
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Pentosan Polysulfate Treatment of Mucopolysaccharidosis Type IIIA Mice
Authors: N Guo, V DeAngelis, C Zhu, EH Schuchman, CM Simonaro
JIMD Rep, 2018-04-14;0(0):.
Species: Mouse
Sample Types: Plasma
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Characterization of the acute inflammatory profile and resolution of airway inflammation after Igf1r-gene targeting in a murine model of HDM-induced asthma
Authors: S Piñeiro-He, E Alfaro-Arn, JA Gregory, R Torrens, C Ruíz-Martí, M Adner, IP López, JG Pichel
PLoS ONE, 2017-12-22;12(12):e0190159.
Species: Mouse
Sample Types: Serum
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Leukotriene B4 is essential for lung host defence and alpha-defensin-1 production during Achromobacter xylosoxidans infection
Authors: MKB Prado, GA Locachevic, KF Zoccal, FWG Paula-Silv, C Fontanari, JC Ferreira, PAT Pereira, LG Gardinassi, SG Ramos, CA Sorgi, ALC Darini, LH Faccioli
Sci Rep, 2017-12-15;7(1):17658.
Species: Mouse
Sample Types: Tissue Homogenates
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CCL3 augments tumor rejection and enhances CD8+T cell infiltration through NK and CD103+dendritic cell recruitment via IFN?
Authors: F Allen, ID Bobanga, P Rauhe, D Barkauskas, N Teich, C Tong, J Myers, AY Huang
Oncoimmunology, 2017-11-20;7(3):e1393598.
Species: Mouse
Sample Types: Serum
Applications: ELISA Capture -
Functional paralysis of GM-CSF-derived bone marrow cells productively infected with ectromelia virus
Authors: L Szulc-D?br, J Struzik, A Ostrowska, M Guzera, FN Toka, M Bossowska-, MM Giery?ska, A Winnicka, Z Nowak, MG Niemia?tow
PLoS ONE, 2017-06-12;12(6):e0179166.
Species: Mouse
Sample Types: Cell Culture Supernates
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B Cell Homeostasis and Functional Properties Are Altered in an Hypochlorous Acid-Induced Murine Model of Systemic Sclerosis
Authors: S Sanges, M Jendoubi, N Kavian, C Hauspie, S Speca, JC Crave, T Guerrier, G Lefèvre, V Sobanski, A Savina, E Hachulla, PY Hatron, M Labalette, F Batteux, S Dubucquoi, D Launay
Front Immunol, 2017-02-07;8(0):53.
Species: Mouse
Sample Types: Cell Culture Supernates
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LRBA is Essential for Allogeneic Responses in Bone Marrow Transplantation
Sci Rep, 2016-11-08;6(0):36568.
Species: Mouse
Sample Types: Cell Culture Supernates
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Activation of the cholinergic anti-inflammatory system by nicotine attenuates arthritis via suppression of macrophage migration
Mol Med Rep, 2016-10-31;14(6):5057-5064.
Species: Mouse
Sample Types: Serum
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Targeting Tumor Cells with Anti-CD44 Antibody Triggers Macrophage-Mediated Immune Modulatory Effects in a Cancer Xenograft Model
PLoS ONE, 2016-07-27;11(7):e0159716.
Species: Mouse
Sample Types: Tissue Homogenates
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Tetanus toxoid and CCL3 improve dendritic cell vaccines in mice and glioblastoma patients.
Authors: Mitchell, Duane A, Batich, Kristen, Gunn, Michael, Huang, Min-Nung, Sanchez-Perez, Luis, Nair, Smita K, Congdon, Kendra L, Reap, Elizabet, Archer, Gary E, Desjardins, Annick, Friedman, Allan H, Friedman, Henry S, Herndon, James E, Coan, April, McLendon, Roger E, Reardon, David A, Vredenburgh, James J, Bigner, Darell D, Sampson, John H
Nature, 2015-03-11;519(7543):366-9.
Species: Mouse
Sample Types: Cell Culture Supernates
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Prostaglandin E2 negatively regulates the production of inflammatory cytokines/chemokines and IL-17 in visceral leishmaniasis.
Authors: Saha A, Biswas A, Srivastav S, Mukherjee M, Das P, Ukil A
J Immunol, 2014-07-21;193(5):2330-9.
Species: Mouse
Sample Types: Cell Culture Supernates
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Celecoxib sensitizes Staphylococcus aureus to antibiotics in macrophages by modulating SIRT1.
Authors: Annamanedi M, Kalle A
PLoS ONE, 2014-06-20;9(6):e99285.
Species: Mouse
Sample Types: Cell Culture Supernates
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CCL3 production by microglial cells modulates disease severity in murine models of retinal degeneration.
Authors: Kohno H, Maeda T, Perusek L, Pearlman E, Maeda A
J Immunol, 2014-03-17;192(8):3816-27.
Species: Mouse
Sample Types: Cell Culture Supernates
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Cleavage of the T cell protein tyrosine phosphatase by the hepatitis C virus nonstructural 3/4A protease induces a Th1 to Th2 shift reversible by ribavirin therapy.
Authors: Brenndorfer E, Brass A, Karthe J, Ahlen G, Bode J, Sallberg M
J Immunol, 2014-01-17;192(4):1671-80.
Species: Mouse
Sample Types: Cell Lysates
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Potential roles of CCR5(+) CCR6(+) dendritic cells induced by nasal ovalbumin plus Flt3 ligand expressing adenovirus for mucosal IgA responses.
Authors: Fukuyama Y, Tokuhara D, Sekine S, Aso K, Kataoka K, Davydova J, Yamamoto M, Gilbert R, Tokuhara Y, Fujihashi K, Kunisawa J, Yuki Y, Kiyono H, McGhee J, Fujihashi K
PLoS ONE, 2013-04-02;8(4):e60453.
Species: Mouse
Sample Types: Cell Culture Supernates
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Environment-mediated drug resistance in Bcr/Abl-positive acute lymphoblastic leukemia.
Authors: Feldhahn, Niklas, Arutyunyan, Anna, Stoddart, Sonia, Zhang, Bin, Schmidhuber, Sabine, Yi, Sun-Ju, Kim, Yong-Mi, Groffen, John, Heisterkamp, Nora
Oncoimmunology, 2012-08-01;1(5):618-629.
Species: Mouse
Sample Types: Cell Culture Supernates
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Suppression of cytokine storm with a sphingosine analog provides protection against pathogenic influenza virus.
Authors: Walsh KB, Teijaro JR, Wilker PR
Proc. Natl. Acad. Sci. U.S.A., 2011-06-29;108(29):12018-23.
Species: Mouse
Sample Types: BALF
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Thymic stromal lymphopoietin is produced by dendritic cells.
Authors: Kashyap M, Rochman Y, Spolski R
J. Immunol., 2011-06-20;187(3):1207-11.
Species: Mouse
Sample Types: BALF
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Repulsive guidance molecule-A (RGM-A) inhibits leukocyte migration and mitigates inflammation.
Authors: Mirakaj V, Brown S, Laucher S, Steinl C, Klein G, Kohler D, Skutella T, Meisel C, Brommer B, Rosenberger P, Schwab JM
Proc. Natl. Acad. Sci. U.S.A., 2011-04-05;108(16):6555-60.
Species: Mouse
Sample Types: Peritoneal Lavage Fluid
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Both FcgammaRIV and FcgammaRIII are essential receptors mediating type II and type III autoimmune responses via FcRgamma-LAT-dependent generation of C5a.
Authors: Syed SN, Konrad S, Wiege K, Nieswandt B, Nimmerjahn F, Schmidt RE, Gessner JE
Eur. J. Immunol., 2009-12-01;39(12):3343-56.
Species: Mouse
Sample Types: BALF
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CCR5 is involved in resolution of inflammation in proteoglycan-induced arthritis.
Authors: Doodes PD, Cao Y, Hamel KM, Wang Y, Rodeghero RL, Kobezda T, Finnegan A
Arthritis Rheum., 2009-10-01;60(10):2945-53.
Species: Mouse
Sample Types: Serum
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Early protection from burn-induced acute lung injury by deletion of preprotachykinin-A gene.
Authors: Sio SW, Moochhala S, Lu J
Am. J. Respir. Crit. Care Med., 2009-10-01;181(1):36-46.
Species: Mouse
Sample Types: Tissue Homogenates
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VAMP8 is essential in anaphylatoxin-induced degranulation, TNF-alpha secretion, peritonitis, and systemic inflammation.
Authors: Pushparaj PN, Tay HK, Wang CC, Hong W, Melendez AJ
J. Immunol., 2009-06-29;183(2):1413-8.
Species: Mouse
Sample Types: Serum
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TLR9 activation coupled to IL-10 deficiency induces adverse pregnancy outcomes.
Authors: Thaxton JE, Romero R, Sharma S
J. Immunol., 2009-06-26;183(2):1144-54.
Species: Mouse
Sample Types: Serum
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Endotoxin augmented antigen-induced Th1 cell trafficking amplifies airway neutrophilic inflammation.
Authors: Mikhak Z, Farsidjani A, Luster AD
J. Immunol., 2009-06-15;182(12):7946-56.
Species: Mouse
Sample Types: BALF
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Mortality following peripheral infection with tick-borne encephalitis virus results from a combination of central nervous system pathology, systemic inflammatory and stress responses.
Authors: Hayasaka D, Nagata N, Fujii Y, Hasegawa H, Sata T, Suzuki R, Gould EA, Takashima I, Koike S
Virology, 2009-05-24;390(1):139-50.
Species: Mouse
Sample Types: Serum
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TLR9 agonist, but not TLR7/8, functions as an adjuvant to diminish FI-RSV vaccine-enhanced disease, while either agonist used as therapy during primary RSV infection increases disease severity.
Authors: Johnson TR, Rao S, Seder RA, Chen M, Graham BS
Vaccine, 2009-04-03;27(23):3045-52.
Species: Mouse
Sample Types: Cell Culture Supernates
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Hypoxia-inducible factor-dependent induction of netrin-1 dampens inflammation caused by hypoxia.
Authors: Rosenberger P, Schwab JM, Mirakaj V, Masekowsky E, Mager A, Morote-Garcia JC, Unertl K, Eltzschig HK
Nat. Immunol., 2009-01-04;10(2):195-202.
Species: Mouse
Sample Types: Serum
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Mechanical ventilation enhances lung inflammation and caspase activity in a model of mouse pneumovirus infection.
Authors: Bem RA, van Woensel JB, Bos AP, Koski A, Farnand AW, Domachowske JB, Rosenberg HF, Martin TR, Matute-Bello G
Am. J. Physiol. Lung Cell Mol. Physiol., 2008-11-07;296(1):L46-56.
Species: Mouse
Sample Types: BALF
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A potential role of thymic stromal lymphopoietin in the recruitment of macrophages to mouse intervertebral disc cells via monocyte chemotactic protein 1 induction: implications for herniated discs.
Authors: Ohba T, Haro H, Ando T, Koyama K, Hatsushika K, Suenaga F, Ohnuma Y, Nakamura Y, Katoh R, Ogawa H, Hamada Y, Nakao A
Arthritis Rheum., 2008-11-01;58(11):3510-9.
Species: Mouse
Sample Types: Cell Culture Supernates
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Role of the chemokine decoy receptor D6 in balancing inflammation, immune activation, and antimicrobial resistance in Mycobacterium tuberculosis infection.
Authors: Di Liberto D, Locati M, Caccamo N, Vecchi A, Meraviglia S, Salerno A, Sireci G, Nebuloni M, Caceres N, Cardona PJ, Dieli F, Mantovani A
J. Exp. Med., 2008-08-11;205(9):2075-84.
Species: Mouse
Sample Types: Serum
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The novel inosine analogue, INO-2002, protects against diabetes development in multiple low-dose streptozotocin and non-obese diabetic mouse models of type I diabetes.
Authors: Mabley JG, Pacher P, Murthy KG, Williams W, Southan GJ, Salzman AL, Szabo C
J. Endocrinol., 2008-06-18;198(3):581-9.
Species: Mouse
Sample Types: Tissue Homogenates
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The neuropeptide substance P is a critical mediator of burn-induced acute lung injury.
Authors: Sio SW, Puthia MK, Lu J, Moochhala S, Bhatia M
J. Immunol., 2008-06-15;180(12):8333-41.
Species: Mouse
Sample Types: Tissue Homogenates
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Pulmonary eosinophilia requires interleukin-5, eotaxin-1, and CD4+ T cells in mice immunized with respiratory syncytial virus G glycoprotein.
Authors: Johnson TR, Rothenberg ME, Graham BS
J. Leukoc. Biol., 2008-06-02;84(3):748-59.
Species: Mouse
Sample Types: Tissue Homogenates
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Functional roles for C5a receptors in sepsis.
Authors: Rittirsch D, Flierl MA, Nadeau BA, Day DE, Huber-Lang M, Mackay CR, Zetoune FS, Gerard NP, Cianflone K, Kohl J, Gerard C, Sarma JV, Ward PA
Nat. Med., 2008-05-04;14(5):551-7.
Species: Mouse
Sample Types: Plasma
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A novel mechanism for CCR4 in the regulation of macrophage activation in bleomycin-induced pulmonary fibrosis.
Authors: Trujillo G, O'Connor EC, Kunkel SL, Hogaboam CM
Am. J. Pathol., 2008-04-10;172(5):1209-21.
Species: Mouse
Sample Types: Tissue Homogenates
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Regulatory T cells control dendritic cell/NK cell cross-talk in lymph nodes at the steady state by inhibiting CD4+ self-reactive T cells.
Authors: Terme M, Chaput N, Combadiere B, Ma A, Ohteki T, Zitvogel L
J. Immunol., 2008-04-01;180(7):4679-86.
Species: Mouse
Sample Types: Cell Culture Supernates
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Adverse functions of IL-17A in experimental sepsis.
Authors: Flierl MA, Rittirsch D, Gao H, Hoesel LM, Nadeau BA, Day DE, Zetoune FS, Sarma JV, Huber-Lang MS, Ferrara JL, Ward PA
FASEB J., 2008-02-25;22(7):2198-205.
Species: Mouse
Sample Types: Plasma
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Peroxisome proliferator-activated receptor-gamma ligand, 15-deoxy-Delta12,14-prostaglandin J2, reduces neutrophil migration via a nitric oxide pathway.
Authors: Napimoga MH, Vieira SM, Dal-Secco D, Freitas A, Souto FO, Mestriner FL, Alves-Filho JC, Grespan R, Kawai T, Ferreira SH, Cunha FQ
J. Immunol., 2008-01-01;180(1):609-17.
Species: Mouse
Sample Types: Tissue Secretion
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IL-17 receptor signaling influences virus-induced corneal inflammation.
Authors: Molesworth-Kenyon SJ, Yin R, Oakes JE, Lausch RN
J. Leukoc. Biol., 2007-11-12;83(2):401-8.
Species: Mouse
Sample Types: Cell Culture Supernates
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Cannabinoid-2 receptor agonist HU-308 protects against hepatic ischemia/reperfusion injury by attenuating oxidative stress, inflammatory response, and apoptosis.
Authors: Rajesh M, Pan H, Mukhopadhyay P, Batkai S, Osei-Hyiaman D, Hasko G, Liaudet L, Gao B, Pacher P
J. Leukoc. Biol., 2007-07-25;82(6):1382-9.
Species: Mouse
Sample Types: Plasma
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The direct action of 1alpha,25(OH)2-vitamin D3 on purified mouse Langerhans cells.
Authors: Fujita H, Asahina A, Komine M, Tamaki K
Cell. Immunol., 2007-05-15;245(2):70-9.
Species: Mouse
Sample Types: Cell Culture Supernates
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Therapeutic targeting of CC ligand 21 or CC chemokine receptor 7 abrogates pulmonary fibrosis induced by the adoptive transfer of human pulmonary fibroblasts to immunodeficient mice.
Authors: Pierce EM, Carpenter K, Jakubzick C, Kunkel SL, Flaherty KR, Martinez FJ, Hogaboam CM
Am. J. Pathol., 2007-04-01;170(4):1152-64.
Species: Mouse
Sample Types: Tissue Homogenates
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Clostridium sordellii lethal toxin kills mice by inducing a major increase in lung vascular permeability.
Authors: Geny B, Khun H, Fitting C, Zarantonelli L, Mazuet C, Cayet N, Szatanik M, Prevost MC, Cavaillon JM, Huerre M, Popoff MR
Am. J. Pathol., 2007-03-01;170(3):1003-17.
Species: Mouse
Sample Types: Serum
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Cannabinoid-2 receptor mediates protection against hepatic ischemia/reperfusion injury.
Authors: Batkai S, Osei-Hyiaman D, Pan H, El-Assal O, Rajesh M, Mukhopadhyay P, Hong F, Harvey-White J, Jafri A, Hasko G, Huffman JW, Gao B, Kunos G, Pacher P
FASEB J., 2007-02-27;21(8):1788-800.
Species: Mouse
Sample Types: Tissue Homogenates
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Protection against inflammation- and autoantibody-caused fetal loss by the chemokine decoy receptor D6.
Authors: Martinez de la Torre Y, Buracchi C, Borroni EM, Dupor J, Bonecchi R, Nebuloni M, Pasqualini F, Doni A, Lauri E, Agostinis C, Bulla R, Cook DN, Haribabu B, Meroni P, Rukavina D, Vago L, Tedesco F, Vecchi A, Lira SA, Locati M, Mantovani A
Proc. Natl. Acad. Sci. U.S.A., 2007-02-05;104(7):2319-24.
Species: Mouse
Sample Types: Serum
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Deficiency of P-selectin or P-selectin glycoprotein ligand-1 leads to accelerated development of glomerulonephritis and increased expression of CC chemokine ligand 2 in lupus-prone mice.
Authors: He X, Schoeb TR, Panoskaltsis-Mortari A, Zinn KR, Kesterson RA, Zhang J, Samuel S, Hicks MJ, Hickey MJ, Bullard DC
J. Immunol., 2006-12-15;177(12):8748-56.
Species: Mouse
Sample Types: Tissue Homogenates
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Metalloelastase (MMP-12) induced inflammatory response in mice airways: effects of dexamethasone, rolipram and marimastat.
Authors: Nenan S, Lagente V, Planquois JM, Hitier S, Berna P, Bertrand CP, Boichot E
Eur. J. Pharmacol., 2006-12-12;559(1):75-81.
Species: Mouse
Sample Types: Tissue Homogenates
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Altered postnatal lung development in C3H/HeJ mice.
Authors: Sampath V, Davis K, Senft AP, Richardson TR, Kitzmiller JA, Berclaz PY, Korfhagen TR
Pediatr. Res., 2006-10-25;60(6):663-8.
Species: Mouse
Sample Types: Tissue Homogenates
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Bim deficiency leads to exacerbation and prolongation of joint inflammation in experimental arthritis.
Authors: Scatizzi JC, Bickel E, Hutcheson J, Haines GK, Perlman H
Arthritis Rheum., 2006-10-01;54(10):3182-93.
Species: Mouse
Sample Types: Tissue Homogenates
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GM-CSF regulates a PU.1-dependent transcriptional program determining the pulmonary response to LPS.
Authors: Berclaz PY, Carey B, Fillipi MD, Wernke-Dollries K, Geraci N, Cush S, Richardson T, Kitzmiller J, O'Connor M, Hermoyian C, Korfhagen T, Whitsett JA, Trapnell BC
Am. J. Respir. Cell Mol. Biol., 2006-08-17;36(1):114-21.
Species: Mouse
Sample Types: Cell Culture Supernates
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The transcriptional response to lipopolysaccharide reveals a role for interferon-gamma in lung neutrophil recruitment.
Authors: Burch LH, Yang IV, Whitehead GS, Chao FG, Berman KG, Schwartz DA
Am. J. Physiol. Lung Cell Mol. Physiol., 2006-06-09;291(4):L677-82.
Species: Mouse
Sample Types: BALF
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Immunosuppressant triptolide inhibits dendritic cell-mediated chemoattraction of neutrophils and T cells through inhibiting Stat3 phosphorylation and NF-kappaB activation.
Authors: Liu Q, Chen T, Chen G, Li N, Wang J, Ma P, Cao X
Biochem. Biophys. Res. Commun., 2006-05-12;345(3):1122-30.
Species: Mouse
Sample Types: Cell Culture Supernates
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Intranasal exposure to Stachybotrys chartarum enhances airway inflammation in allergic mice.
Authors: Leino MS, Alenius HT, Fyhrquist-Vanni N, Wolff HJ, Reijula KE, Hintikka EL, Salkinoja-Salonen MS, Haahtela T, Mäkelä MJ
Am. J. Respir. Crit. Care Med., 2005-12-01;173(5):512-8.
Species: Mouse
Sample Types: BALF
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MyD88-dependent and -independent murine cytomegalovirus sensing for IFN-alpha release and initiation of immune responses in vivo.
Authors: Delale T, Paquin A, Asselin-Paturel C, Dalod M, Brizard G, Bates EE, Kastner P, Chan S, Akira S, Vicari A, Biron CA, Trinchieri G, Briere F
J. Immunol., 2005-11-15;175(10):6723-32.
Species: Mouse
Sample Types: Serum
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Immunization with gp120-depleted whole killed HIV immunogen and a second-generation CpG DNA elicits strong HIV-specific responses in mice.
Authors: Trabattoni D, Clivio A, Bray DH, Bhagat L, Beltrami S, Maffeis G, Cesana E, Lowry P, Lissoni F, Kandimalla ER, Sullivan T, Agrawal S, Bartholomew R, Clerici M
Vaccine, 2005-09-22;24(9):1470-7.
Species: Mouse
Sample Types: Cell Culture Supernates
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Vbeta14(+) T cells mediate the vaccine-enhanced disease induced by immunization with respiratory syncytial virus (RSV) G glycoprotein but not with formalin-inactivated RSV.
Authors: Johnson TR, Varga SM, Braciale TJ, Graham BS
J. Virol., 2004-08-01;78(16):8753-60.
Species: Mouse
Sample Types: Tissue Homogenates
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The role of gammadelta T cells in the regulation of neutrophil-mediated tissue damage after thermal injury.
Authors: Toth B, Alexander M, Daniel T, Hubbard WJ, Schwacha MG
J. Leukoc. Biol., 2004-06-14;76(3):545-52.
Species: Mouse
Sample Types: Plasma
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Effects of poly(ADP-ribose) polymerase inhibition on inflammatory cell migration in a murine model of asthma.
Authors: Virag L, Bai P, Bak I, Pacher P, Mabley JG, Liaudet L, Bakondi E, Gergely P, Kollai M, Szabo C
Med. Sci. Monit., 2004-03-01;10(3):BR77-83.
Species: Mouse
Sample Types: BALF
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Chemokine and cytokine production during Orientia tsutsugamushi infection in mice.
Authors: Koh YS, Yun JH, Seong SY, Choi MS, Kim IS
Microb. Pathog., 2004-01-01;36(1):51-7.
Species: Mouse
Sample Types: Peritoneal Fluid
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Resident cell chemokine expression serves as the major mechanism for leukocyte recruitment during local inflammation.
Authors: Garcia-Ramallo E, Marques T, Prats N, Beleta J, Kunkel SL, Godessart N
J. Immunol., 2002-12-01;169(11):6467-73.
Species: Mouse
Sample Types: Air Pouch Exudate
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Role of the autocrine chemokines MIP-1alpha and MIP-1beta in the metastatic behavior of murine T cell lymphoma.
Authors: Menten P, Saccani A, Dillen C, Wuyts A, Struyf S, Proost P, Mantovani A, Wang JM, Van Damme J
J. Leukoc. Biol., 2002-10-01;72(4):780-9.
Species: Mouse
Sample Types: Cell Culture Supernates
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Cutting edge: myeloid differentiation factor 88 deficiency improves resistance against sepsis caused by polymicrobial infection.
Authors: Weighardt H, Bê Ë„Æ%í, Kaiser-Moore S, Vabulas RM, Kirschning CJ, Wagner H, Holzmann B
2002-09-15;169(6):2823-7.
Species: Mouse
Sample Types: Serum
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The role of lipopolysaccharide binding protein in resistance to Salmonella infections in mice.
Authors: Fierer J, Swancutt MA, Heumann D, Golenbock D
J. Immunol., 2002-06-15;168(12):6396-403.
Species: Mouse
Sample Types: Interperitoneal Fluid
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Immunostimulatory DNA-based vaccines elicit multifaceted immune responses against HIV at systemic and mucosal sites.
Authors: Horner AA, Datta SK, Takabayashi K, Belyakov IM, Cinman N, Nguyen MD, Van Uden JH, Berzofsky JA
J. Immunol., 2001-08-01;167(3):1584-91.
Species: Mouse
Sample Types: Cell Culture Supernates
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The protein tyrosine kinase inhibitor AG126 prevents the massive microglial cytokine induction by pneumococcal cell walls.
Authors: Hanisch UK, Prinz M, Angstwurm K, Hausler KG, Kann O, Kettenmann H, Weber JR
Eur. J. Immunol., 2001-07-01;31(7):2104-15.
Species: Mouse
Sample Types: Cell Culture Supernates
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Pulmonary eosinophilia and production of MIP-1alpha are prominent responses to infection with pneumonia virus of mice.
Authors: Domachowske JB, Bonville CA, Dyer KD, Easton AJ, Rosenberg HF
Cell. Immunol., 2000-03-15;200(2):98-104.
Species: Mouse
Sample Types: BALF
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