Mouse Fc gamma RIII (CD16) (NP_034318) VersaClone cDNA

Catalog #: RDC1432 Datasheet / COA / SDS

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RDC1432

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Mouse Fc gamma RIII (CD16) (NP_034318) VersaClone cDNA Summary

Specifications

Source

N/A

Shipping Conditions

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Species

Mouse

Product Datasheets

Product Datasheet

COA

SDS

Background: Fc gamma RIII (CD16)

Receptors that recognize the Fc portion of IgG are divided into three groups designated Fc gamma RI, RII, and RIII, also known respectively as CD64, CD32, and CD16. In humans each group of receptors is encoded by 2 - 3 closely related genes designated A, B, and C. Fc gamma RI binds IgG with high affinity and functions during early immune responses. Fc gamma RII and RIII are low affinity receptors that recognize IgG as aggregates surrounding multivalent antigens during late immune responses. Different Fc receptors can function as activators, as inhibitors, or as decoy receptors.

Long Name

Fc gamma Receptor III

Entrez Gene IDs

14131 (Mouse); 102140945 (Cynomolgus Monkey)

Alternate Names

CD16; CD16A; Fc fragment of IgG receptor IIIa; Fc gamma RIII; FCG3; FCGR3; FcgRIII; FCR-10; FCRIII; FCRIIIA; IGFR3; IMD20