Mouse Plasminogen Kringle 5 Antibody

Catalog #: MAB742
1 Citation Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
MAB742
MAB742-SP

Product Details

Citations (1)

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Mouse Plasminogen Kringle 5 Antibody Summary

Species Reactivity

Mouse

Specificity

Detects mouse Plasminogen Kringle 5 in direct ELISAs and Western blots. In direct ELISAs, no cross‑reactivity with recombinant human Plasminogen Kringle 5 is observed.

Source

Monoclonal Rat IgG₁ Clone # 120304

Purification

Protein A or G purified from hybridoma culture supernatant

Immunogen

E. coli-derived recombinant mouse Plasminogen Kringle 5
Cys481-Ala563
Accession # AAA50168

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Purity

Protein A or G purified from hybridoma culture supernatant

Applications

Recommended Concentration

Sample

Western Blot

1 µg/mL

Recombinant Mouse Plasminogen Kringle 5

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Plasminogen Kringle 5

Plasminogen is a coenzyme that has five triple disulfide-linked kringle domains. It is converted to plasmin by plasminogen activators. Internal fragments of plasminogen, including the naturally occurring angiostatin isoforms and Kringle 5, can also be generated by proteolytic cleavage. These internal fragments have been shown to be potent angiogenesis inhibitors (1).

References

Cao, Y. et al. (1997) J. Biol. Chem. 272:22924.

Entrez Gene IDs

5340 (Human); 18815 (Mouse); 85253 (Rat)

Alternate Names

HAE4; Plasminogen Kringle 5

Product Datasheets

Product Datasheet

COA

SDS

Related Research Areas

Citation for Mouse Plasminogen Kringle 5 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

Histone H2B as a functionally important plasminogen receptor on macrophages.
Authors: Das R, Burke T, Plow EF
Blood, 2007-08-09;110(10):3763-72.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC