Mouse/Rat TSC22 Antibody

Catalog #: AF3779
1 Citation Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
AF3779
AF3779-SP

All TSC22 Antibodies

Product Details

Citations (1)

Supplemental Products

Reviews

Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Mouse/Rat TSC22 Antibody Summary

Species Reactivity

Mouse, Rat

Specificity

Detects mouse and rat TSC22 in direct ELISAs and Western blots.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

E. coli-derived recombinant mouse TSC22
Met1-Ala143
Accession # P62500.2

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Label

Unconjugated

Purity

Immunogen affinity purified

Applications

Recommended Concentration

Sample

Western Blot

0.1 µg/mL

Recombinant Mouse TSC22

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: TSC22

Mouse TSC22 is an intracellular 18 kDa (143 aa) protein that belongs to the TSC22/Dip/Bun family of leucine zipper transcription regulators. Family members share a highly conserved central TSC box-leucine zipper domain that is important for dimerization and distinct N- and C-termini that participate in transcriptional regulation. TSC22 can homodimerize or heterodimerize with other family members to function as a repressive transcription factor. Mouse TSC22 shares 100% and 98.5% amino acid sequence homology with rat and human TSC22, respectively.

Long Name

TSC22 Domain Family, Member 1

Entrez Gene IDs

8848 (Human); 21807 (Mouse)

Alternate Names

Cerebral protein 2; Egr5; KIAA1994; MGC17597; Regulatory protein TSC-22; RP11-269C23.2; TGFB1I4; TGFB-stimulated clone 22 homolog; transforming growth factor beta 1 induced transcript 4; Transforming growth factor beta-1-induced transcript 4 protein; transforming growth factor beta-stimulated protein TSC-22; TSC22 domain family 1; TSC22 domain family protein 1; TSC22 domain family, member 1; TSC22; TSC22D1; TSC22DKFZp686O19206

Product Datasheets

Product Datasheet

COA

SDS

Related Research Areas

Citation for Mouse/Rat TSC22 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

Post-transcriptional up-regulation of Tsc-22 by Ybx1, a target of miR-216a, mediates TGF-{beta}-induced collagen expression in kidney cells.
Authors: Kato M, Wang L, Putta S, Wang M, Yuan H, Sun G, Lanting L, Todorov I, Rossi JJ, Natarajan R
J. Biol. Chem., 2010-08-16;285(44):34004-15.
Species: Mouse
Sample Types: Cell Lysates, Whole Tissue
Applications: IHC, Western Blot