Mouse Reg1 Biotinylated Antibody

Catalog #: BAF1657 Datasheet / COA / SDS

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BAF1657

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Mouse Reg1 Biotinylated Antibody Summary

Species Reactivity

Mouse

Specificity

Detects mouse Reg1 in Western blots. In this format, approximately 10% cross-reactivity with recombinant mouse (rm) Reg2 is observed and less than 5% cross-reactivity with rmReg3A, recombinant human (rh) Reg1B, rhReg4 and recombinant rat Reg3 is observed.

Source

Polyclonal Sheep IgG

Purification

Antigen Affinity-purified

Immunogen

E. coli-derived recombinant mouse Reg1
Gln22-Gly165
Accession # P43137

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.

Label

Biotin

Purity

Antigen Affinity-purified

Applications

Recommended Concentration

Sample

Western Blot

0.1 µg/mL

Recombinant Mouse Reg1

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Reg1

Reg1, also known as pancreatic thread protein (PTP), pancreatic stone protein (PSP) and lithostathine, is the founding member of the Reg family of proteins, which are secreted proteins with a C-type lectin domain. Reg1 is expressed during islet regeneration. Reg1 functions in an autocrine/paracrine fashion via a cell surface Reg receptor that mediates a growth signal for beta -cell regeneration (1).

References

Okamoto, H. and S. Takasawa (2002) Diabetes 51:5462.

Long Name

Regenerating Islet-derived 1

Entrez Gene IDs

19692 (Mouse)

Alternate Names

ICRF; Islet cells regeneration factor; Islet of Langerhans regenerating protein; lithostathine-1-alpha; Pancreatic stone protein; pancreatic stone protein, secretory; Pancreatic thread protein; protein-X; PSPregenerating islet-derived 1 alpha (pancreatic stone protein, pancreatic threadprotein); PSPS1REG-1-alpha; PSPSMGC12447; PTPP19; Reg1; regenerating islet-derived 1 alpha; Regenerating islet-derived protein 1-alpha; Regenerating protein I alpha; REGlithostathine 1 alpha