Mouse Reg3A Antibody

Catalog #: AF3907 Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
AF3907
AF3907-SP

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Mouse Reg3A Antibody Summary

Species Reactivity

Mouse

Specificity

Detects mouse Reg3A in direct ELISAs and Western blots. In these formats, less than 1% cross-reactivity with recombinant human Reg1B and recombinant mouse Reg1 is observed.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

E. coli-derived recombinant mouse Reg3A (R&D Systems, Catalog # 3907-RG)
Glu27-Gln175
Accession # O09037

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Purity

Immunogen affinity purified

Applications

Recommended Concentration

Sample

Western Blot

0.1 µg/mL

Recombinant Mouse Reg3A (Catalog # 3907-RG)

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Reg3A

Regenerating islet-derived protein III alpha (Reg3A), also named Pancreatitis Associated-Protein 2 (PAP-2), is a secreted, 17 kDa member of the Reg family. These C-type lectin superfamily proteins are involved in various biological functions, including liver and pancreatic regeneration and proliferation. Reg3A is predominately expressed in intestine and exocrine pancreas. It is also induced in primary liver tumors but is not expressed in normal liver. Mature mouse Reg3A contains 149 amino acid residues and shares less than 60% aa sequence identity with other Reg3 proteins. The protein sequence of mouse Reg3A is 87% and 61% identical to that of rat and human Reg3A, respectively.

Long Name

Regenerating Islet-derived IIIa

Entrez Gene IDs

5068 (Human); 19694 (Mouse); 171162 (Rat)

Alternate Names

hepatocarcinoma-intestine-pancreas; HIPpancreatitis-associated protein; Human proislet peptide; Lithostathine 3; pancreatic beta cell growth factor; Pancreatitis-associated protein 1; PAP homologous protein; PAP1FLJ18565; PAP2; PAPPAP-H; PBCGF; proliferation-inducing protein 34; proliferation-inducing protein 42; Reg III-alpha; REG3; Reg3A; REG-3-alpha; regenerating islet-derived 3 alpha; regenerating islet-derived protein 3-alpha; Regenerating islet-derived protein III-alpha; REG-III