Nor NOHA monoacetate

Biological Activity

Technical Data

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

1. The new α-amino acid N^ω-hydroxy-nor-L-arginine: a high affinity inhibitor of arginase well adapted to bind to its manganese cluster.
   Custot et al.
   J.Am.Chem.Soc., 1997;119:4086
2. Classical and slow-binding inhibitors of human type II arginase.
   Colleluori and Ash et al.
   Biochemistry, 2001;40:9356
3. The vascular effects of different arginase inhibitors in rat isolated aorta and mesenteric arteries.
   Huynh et al.
   Br.J.Pharmacol., 2009;156:84
4. Arginase I production in the tumor microenvironment by mature myeloid cells inhibits T-cell receptor expression and antigen-specific T-cell responses.
   Rodriguez et al.
   Cancer Res., 2004;64:5839

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