Orexin B (mouse)

Catalog #: 1457
3 Citations Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
1457/500U

1 Image

Description: Endogenous agonist at OX1 and OX2

Purity: ≥95%

View All Products for Orexin Receptor Agonists

Product Details

Citations (3)

Reviews

Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

Orexin B (mouse) is an endogenous agonist at orexin receptors. May be involved in the regulation of feeding, sleep-wake cycle and other hypothalamic functions. Orexin B exerts excitatory effects on nigral dopaminergic neurons and alleviates motor symptoms in a Parkinson's disease mouse model.

Technical Data

M.Wt:

2936.43

Formula:

C₁₂₆H₂₁₅N₄₅O₃₄S

Sequence:

RPGPPGLQGRLQRLLQANGNHAAGILTM

(Modification: Met-28 = C-terminal amide)

Solubility:

Soluble to 1 mg/ml in water

Purity:

≥95%

Storage:

Store at -20°C

CAS No:

202801-92-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

The hypocretin/orexin ligand-receptor system: implications for sleep and sleep disorders.
Kilduff and Peyron
TiNS, 2000;23:359
Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behaviour.
Sakurai et al.
Cell, 1998;92:573
Orexins: a new family of neuropeptides.
Smart
Br.J.Anaesth., 1999;83:695

Product Datasheets

COA view current batch

Or select another batch:

View Batch

SDS

Reconstitution Calculator

Molarity Calculator

Reconstitution Calculator

Molarity Calculator

Mass

Concentration

Volume

M. Wt* g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Citations for Orexin B (mouse)

The citations listed below are publications that use Tocris products. Selected citations for Orexin B (mouse) include:

3 Citations: Showing 1 - 3

Orexin-B exerts excitatory effects on nigral dopaminergic neurons and alleviates motor disorders in MPTP parkinsonian mice
Authors: Bian Et al.
Neurosci Lett 2021;765:136291
OX2R activation induces PKC-mediated ERK and CREB phosphorylation.
Authors: Guo and Feng
Exp Cell Res 2012;318:2004
Orexin 1 receptor activation attenuates neurogenic dural vasodilation in an animal model of trigeminovascular nociception.
Authors: Holland Et al.
J Biol Chem 2005;315:1380

FAQs

No product specific FAQs exist for this product, however you may

View all Peptide FAQs

Reviews for Orexin B (mouse)

There are currently no reviews for this product. Be the first to review Orexin B (mouse) and earn rewards!

Have you used Orexin B (mouse)?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.