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P-3FAX-Neu5Ac

Catalog #: 5760 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
5760/10
P-3FAX-Neu5Ac | CAS No. 117405-58-0 | Other Transferase Inhibitors
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Description: Sialic acid analog; sialyltransferase inhibitor

Chemical Name: 5-(acetylamino)-3,5-dideoxy-3-fluoro-D-erythro-α-L-manno-2-nonulopyranosonic acid methyl ester 2,4,7,8,9-pentaacetate

Purity: ≥97%

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Biological Activity

P-3FAX-Neu5Ac is a cell-permeable sialic acid analog. Deacetylation occurs intracellularly giving rise to a sialyltransferase inhibitor. Abolishes expression of SLex expression on HL-60 cells and reduces E-selectin and P-selectin binding. Prevents metastasis formation in a mouse lung metastasis model.

Technical Data

M.Wt:
551.47
Formula:
C22H30FNO14
Solubility:
Soluble to 100 mM in DMSO and to 50 mM in ethanol
Purity:
≥97%
Storage:
Store at -20°C
CAS No:
117405-58-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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