p-Chlorophenylalanine
Purity: ≥99%
Biological Activity
p-Chlorophenylalanine is a binds irreversibly to tryptophan hydroxylase to cause depletion of serotonin in the brain.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Effect of p-chlorophenylalanine at moderate dosage on 5-HT and 5-HIAA concentrations in brain regions of control and p-chloroamphetamine treated rats.
Datla and Curzon
Neuropharmacology, 1996;35:315 -
The effects of DL-p-chlorophenylalanine and DL-α-methyl-p-tyrosine on the brain catecholamine, serotonin and free amino acid contents in rat.
Koyuncuoglu et al.
Psychopharmacologia, 1975;45:163
Product Datasheets
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Citations for p-Chlorophenylalanine
The citations listed below are publications that use Tocris products. Selected citations for p-Chlorophenylalanine include:
2 Citations: Showing 1 - 2
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NAD+ protects against EAE by regulating CD4+ T-cell differentiation.
Authors: Tullius Et al.
Nat Commun 2014;5:5101
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Mammary gland serotonin regulates parathyroid hormone-related protein and other bone-related signals.
Authors: Hernandez Et al.
Proc Natl Acad Sci U S A 2012;302:E1009
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