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PARP/Apoptosis Chemiluminescent Assay Kit

Catalog #: 4685-096-K
1 Citation Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
4685-096-K
Product Details
Citations (1)
FAQs
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Summary Product Datasheets Background

PARP/Apoptosis Chemiluminescent Assay Kit Summary

Specifications

Shipping Conditions
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Species
Multi-Species

Product Datasheets

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Product Datasheet
COA
SDS

Background: PARP

PARP [Poly(ADP-ribose) Polymerase], also known as ADPRT and PPOL, is a 118-kDa enzyme that uses NAD as a substrate to catalyze the covalent transfer of ADP-ribose to a variety of nuclear protein acceptors. ADP ribosyltransferase is required for cellular repair, and PARP expression is induced by single-strand breaks in DNA. PARP is proteolytically cleaved by Caspase-3 into two fragments of 89- and 24-kDa in one of the hallmark events of apoptosis.

Long Name
Poly [ADP-ribose] Polymerase
Entrez Gene IDs
142 (Human); 11545 (Mouse)
Alternate Names
ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase); ADPRT 1; ADPRT; ADPRTADP-ribosyltransferase NAD(+); EC 2.4.2; EC 2.4.2.30; NAD(+) ADP-ribosyltransferase 1; PARP apoptosis; PARP; PARP1; PARP-1; PARPADPRT1; poly (ADP-ribose) polymerase 1; poly (ADP-ribose) polymerase family, member 1; poly [ADP-ribose] polymerase 1; poly(ADP-ribose) polymerase; poly(ADP-ribose) synthetase; poly(ADP-ribosyl)transferase; Poly[ADP-ribose] synthase 1; PPOL; PPOLpADPRT-1

Citation for PARP/Apoptosis Chemiluminescent Assay Kit

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

  1. MUC1-C INTEGRATES CHROMATIN REMODELING AND PARP1 ACTIVITY IN THE DNA DAMAGE RESPONSE OF TRIPLE-NEGATIVE BREAST CANCER CELLS
    Authors: M Yamamoto, C Jin, T Hata, Y Yasumizu, Y Zhang, D Hong, T Maeda, M Miyo, M Hiraki, Y Suzuki, K Hinohara, H Rajabi, D Kufe
    Cancer Res., 2019-03-01;0(0):.  2019-03-01

FAQs

  1. Is it possible to purchase a smaller version of the PARP/Apoptosis Chemiluminescent Assay Kit?

    • R&D Systems does not offer a smaller version of this kit. However, plates are provided in stripwell format, so the user is able to test fewer wells and save the remaining plate strips for later use.

  2. Is it possible to test partial plates when using the PARP/Apoptosis Chemiluminescent Assay Kit?

    • The histone-coated plates are provided in stripwell format. To run partial plates, remove excess microplate strips, seal in the provided pouch, and store at 2-8 °C with a dessicant.

View all DNA Damage and Repair Kit FAQs

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