Home / Non-selective mAChR Agonists / Pilocarpine hydrochloride

Pilocarpine hydrochloride

Catalog #: 0694
3 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
0694/100
Pilocarpine hydrochloride | CAS No. 54-71-7 | Non-selective mAChR Agonists
1 Image
Description: Muscarinic agonist

Chemical Name: (3S-cis)-3-Ethyldihydro-4-[(1-methyl-1H-imidazol-5-yl)methyl]-2(3H)-furanone hydrochloride

Purity: ≥98%

Product Details
Citations (3)
Supplemental Products
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

Pilocarpine hydrochloride is an M3 muscarinic acetycholine receptor agonist.

Technical Data

M.Wt:
244.72
Formula:
C11H16N2O2.HCl
Solubility:
Soluble to 75 mM in DMSO and to 100 mM in water
Purity:
≥98%
Storage:
Desiccate at RT
CAS No:
54-71-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. PilC modulates the cellular electrical properties of mammalian hearts by activating a cardiac M3 receptor and a K+ current.
    Wang et al.
    Br.J.Pharmacol., 1999;126:1725
  2. Muscarinic receptor agonists and antagonists.
    Brown and Taylor
    The Pharmacological Basis of Therapeutics. Eds Goo, 1996;:Chapter 7, p147
  3. Differences in the prejunctional effects of methach. and PilC on the release of endogenous acetylcholine from guinea-pig trachea.
    ten Berge et al.
    Naunyn Schmiedebergs Arch.Pharmacol., 1996;354:606

Product Datasheets

COA view current batch
Or select another batch:
View Batch
SDS
Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Citations for Pilocarpine hydrochloride

The citations listed below are publications that use Tocris products. Selected citations for Pilocarpine hydrochloride include:

3 Citations: Showing 1 - 3

  1. The structure of the trabecular meshwork, its connections to the ciliary muscle, and the effect of PilC on outflow facility in mice.
    Authors: Overby Et al.
    Nat Chem Biol  2014;55:3727
  2. Label-free cell phenotypic assessment of the biased agonism and efficacy of agonists at the endogenous muscarinic M3 receptors.
    Authors: Deng Et al.
    J Pharmacol Toxicol Methods  2013;68:323
  3. Glutamate carboxypeptidase II (GCPII) inhibitor displays anti-glutamate and anti-cocaine effects in an invertebrate assay.
    Authors: Tallarida Et al.
    Amino Acids  2012;42:2521

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for Pilocarpine hydrochloride

There are currently no reviews for this product. Be the first to review Pilocarpine hydrochloride and earn rewards!

Have you used Pilocarpine hydrochloride?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.