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Pritelivir

Catalog #: 7321 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
7321/50
Pritelivir | CAS No. 348086-71-5 | Antiviral Compounds
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Description: Potent and selective herpes simplex virus (HSV) helicase primase inhibitor

Chemical Name: N-[5-(Aminosulfonyl)-4-methyl-2-thiazolyl]-N-methyl-4-(2-pyridinyl)benzeneacetamide

Purity: ≥98%

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Biological Activity

Pritelivir is a potent and selective herpes simplex virus (HSV) helicase primase inhibitor. Pritelivir inhibits viral replication in Vero cells (IC50 = 0.02 μM for HSV-1 and HSV-2). It also reduces β-amyloid and P-tau levels in Vero cells. Pritelivir is active against clinical isolates and porcine and bovine HSV strains but displays reduced activity against varicella zoster virus and cytomegalovirus in vitro. In addition, the compound exhibits antiviral activity in HSV infected mice.

Technical Data

M.Wt:
402.49
Formula:
C18H18N4O3S2
Solubility:
Soluble to 50 mM in DMSO with gentle warming
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
348086-71-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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