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Rat TNF-alpha Quantikine ELISA Kit

Catalog #: RTA00
232 Citations 12 Reviews Datasheet / COA / SDS
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PRTA00
SRTA00
RTA00-1
Rat TNF-alpha ELISA Standard Curve
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Citations (232)
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Summary Precision Recovery Linearity Data Examples Product Datasheets Preparation and Storage Background Related Research Areas

Rat TNF-alpha Quantikine ELISA Kit Summary

Assay Type
Solid Phase Sandwich ELISA
Format
96-well strip plate
Assay Length
4.5 hours
Sample Type & Volume Required Per Well
Cell Culture Supernates (17 uL), Serum (25 uL), EDTA Plasma (25 uL), Heparin Plasma (25 uL)
Sensitivity
5 pg/mL
Assay Range
12.5 - 800 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma)
Specificity
Natural and recombinant rat TNF-alpha
Cross-reactivity
< 0.5% cross-reactivity observed with available related molecules.< 50% cross-species reactivity observed with species tested.
Interference
No significant interference observed with available related molecules.

Product Summary

The Quantikine Rat TNF-alpha Immunoassay is a 4.5 hour solid phase ELISA designed to measure rat TNF-alpha levels in cell culture supernates, serum, and plasma. It contains E. coli-expressed recombinant rat TNF-alpha and antibodies raised against the recombinant factor. This immunoassay has been shown to quantitate the recombinant rat TNF-alpha accurately. Results obtained using natural rat TNF-alpha showed dose response curves that were parallel to the standard curves obtained using the recombinant kit standards. These results indicate that this kit can be used to determine relative mass values for natural rat TNF-alpha.

Precision

Intra-Assay Precision (Precision within an assay)
Inter-Assay Precision (Precision between assays)

Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma

Intra-Assay Precision Inter-Assay Precision
Sample 1 2 3 1 2 3
n 20 20 20 20 20 20
Mean (pg/mL) 65 232 593 63 246 656
Standard Deviation 3.3 5.1 12.5 6.1 23.6 57.6
CV% 5.1 2.2 2.1 9.7 9.6 8.8

Recovery

The recovery of rat TNF-alpha spiked to three levels throughout the range of the assay in various matrices was evaluated.

Sample Type Average % Recovery Range %
Cell Culture Supernates (n=6) 101 93-119
EDTA Plasma (n=5) 96 88-104
Heparin Plasma (n=4) 80 73-84
Serum (n=8) 93 83-105

Linearity

To assess the linearity of the assay, samples spiked with various concentrations of rat TNF-alpha were diluted with Calibrator Diluent and then assayed. Results from typical sample dilutions are shown.
Rat TNF-alpha ELISA Linearity

Scientific Data

N/A Rat TNF-alpha ELISA Standard Curve View Larger

Rat TNF-alpha ELISA Standard Curve

Product Datasheets

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Product Datasheet
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Preparation and Storage

Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: TNF-alpha

Tumor necrosis factor alpha (TNF-alpha ), also known as cachectin and TNFSF1A, is the prototypic ligand of the TNF superfamily (1). It is a pleiotropic molecule that plays a central role in inflammation, immune system development, apoptosis, and lipid metabolism (2-5). TNF-alpha is also involved in a number of pathological conditions including asthma, Crohn's disease, rheumatoid arthritis, neuropathic pain, obesity, type 2 diabetes, septic shock, autoimmunity, and cancer (5-11).  

Rat TNF-alpha is synthesized as a 26 kDa type II transmembrane protein that consists of a 35 amino acid (aa) cytoplasmic domain, a 21 aa transmembrane segment, and a 156 aa extracellular domain (ECD) (12). Within the ECD, rat TNF-alpha shares 95% aa sequence identity with mouse, and 73% - 79% aa identity with bovine, canine, cotton rat, equine, feline, human, rhesus macaque, and porcine  TNF-alpha. It is produced by a wide variety of immune, epithelial, endothelial, and tumor cells. TNF-alpha is assembled intracellularly to form a noncovalently linked homotrimer which is expressed on the cell surface (13). Cell surface TNF-alpha can both induce the lysis of tumor cells and virus infected cells, and generate its own downstream cell signaling following ligation by soluble TNF RI (14, 15). Shedding of membrane bound TNF-alpha by TACE/ADAM17 releases the bioactive cytokine, a 55 kDa soluble trimer of the TNF-alpha extracellular domain (16-18).  
TNF-alpha binds the ubiquitous 55 - 60 kDa TNF RI (19, 20) and the hematopoietic cell-restricted 78-80 kDa TNF RII (21, 22), both of which are also expressed as homotrimers (1, 23). Both type I and type II receptors bind TNF-alpha with comparable affinity and can promote NF kappa B activation (24-27). Only TNF RI, however, contains a cytoplasmic death domain which triggers the activation of apoptosis (3, 28). Soluble forms of both types of receptors are released into human serum and urine and can neutralize the biological activity of TNF-alpha (29-31).

Long Name:
Tumor Necrosis Factor alpha
Entrez Gene IDs:
7124 (Human); 21926 (Mouse); 24835 (Rat); 397086 (Porcine); 280943 (Bovine); 403922 (Canine); 102139631 (Cynomolgus Monkey); 100033834 (Equine); 493755 (Feline); 100009088 (Rabbit)
Alternate Names:
APC1 protein; Cachectin; Cachetin; DIF; TNF; TNF, monocyte-derived; TNFA; TNF-A; TNFalpha; TNF-alpha; TNF-alphacachectin; TNFATNF, macrophage-derived; TNFG1F; TNFSF1A; TNFSF2; TNFSF2TNF superfamily, member 2; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; Tumor necrosis factor ligand superfamily member 2; tumor necrosis factor; tumor necrosis factor-alpha
⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Assay Procedure

Refer to the product for complete assay procedure.

Bring all reagents and samples to room temperature before use. It is recommended that all samples, standards, and controls be assayed in duplicate.
  1.   Prepare all reagents, standard dilutions, and samples as directed in the product insert.
  2.   Remove excess microplate strips from the plate frame, return them to the foil pouch containing the desiccant pack, and reseal.
    3. 50 µL Assay Diluent
  3.   Add 50 µL of Assay Diluent to each well.
    4. 50 µL Standard, Control, or Sample
  4.   Add 50 µL of Standard, Control, or sample to each well. Cover with a plate sealer, and incubate at room temperature for 2 hours.
  5.   Aspirate each well and wash, repeating the process 4 times for a total of 5 washes.
    6. 100 µL Conjugate
  6.   Add 100 µL of Conjugate to each well. Cover with a new plate sealer, and incubate at room temperature for 2 hours.
  7.   Aspirate and wash 5 times.
    8. 100 µL Substrate Solution
  8.   Add 100 µL Substrate Solution to each well. Incubate at room temperature for 30 minutes. PROTECT FROM LIGHT.
    9. 100 µL Stop Solution
  9.   Add 100 µL of Stop Solution to each well. Read at 450 nm within 30 minutes. Set wavelength correction to 540 nm or 570 nm.

Citations for Rat TNF-alpha Quantikine ELISA Kit

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

232 Citations: Showing 1 - 10
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  1. Allicin protects against LPS-induced cardiomyocyte injury by activating Nrf2-HO-1 and inhibiting NLRP3 pathways
    Authors: Sun, F;Xu, K;Zhou, J;Zhang, W;Duan, G;Lei, M;
    BMC cardiovascular disorders
    Species: Rat
    Sample Types: Cell Culture Supernates
    Applications: ELISA
  2. The protective effects of sesamol and/or the probiotic, Lactobacillus rhamnosus, against aluminum chloride-induced neurotoxicity and hepatotoxicity in rats: Modulation of Wnt/?-catenin/GSK-3?, JAK-2/STAT-3, PPAR-?, inflammatory, and apoptotic pathways
    Authors: Abu-Elfotuh, K;Selim, HMRM;Riad, OKM;Hamdan, AME;Hassanin, SO;Sharif, AF;Moustafa, NM;Gowifel, AMH;Mohamed, MYA;Atwa, AM;Zaghlool, SS;El-Din, MN;
    Frontiers in pharmacology
    Species: Rat
    Sample Types: Tissue Homogenates
  3. Natural antioxidant formula ameliorates lipopolysaccharide-induced impairment of hippocampal neurogenesis and contextual fear memory through suppression of neuroinflammation in rats
    Authors: Zeng, W;Takashima, K;Tang, Q;Zou, X;Ojiro, R;Ozawa, S;Jin, M;Ando, Y;Yoshida, T;Shibutani, M;
    Journal of chemical neuroanatomy
    Species: Rat
    Sample Types: Tissue Homogenates
  4. Ameliorative effect of cheqianzi decoction on hyperuricemia and kidney injury and underlying mechanism in rats
    Authors: J Meng, J Tian, Y Zhao, C Li, Y Yi, Y Zhang, J Han, L Wang, C Pan, S Liu, C Liu, F Wang, X Tang, D Wang, S Qin, A Liang
    Heliyon, 2023-04-11;9(4):e15333.
    Species: Rat
    Sample Types: Tissue Homogenates
  5. Supplementation with okra�combined or not with exercise training is able to protect the heart of animals with metabolic syndrome
    Authors: MFP Gomes, EOC de Moura, NM Cardoso, GA da Silva, ACC Dos Santos, FS de Souza, D Estadella, RH Lambertucc, JHG Lago, A Medeiros
    Scientific Reports, 2023-01-26;13(1):1468.
    Species: Rat
    Sample Types: Tissue Homogenates
  6. Yiyi Fuzi Baijiang Powder Alleviates Dextran Sulfate Sodium-Induced Ulcerative Colitis in Rats via Inhibiting the TLR4/NF-kappaB/NLRP3 Inflammasome Signaling Pathway to Repair the Intestinal Epithelial Barrier, and Modulating Intestinal Microbiota
    Authors: J Yang, L Miao, Y Xue, X Wang
    Oxidative Medicine and Cellular Longevity, 2023-01-14;2023(0):3071610.
    Species: Rat
    Sample Types: Tissue Homogenates
  7. Ameliorative effect of cheqianzi decoction on hyperuricemia and kidney injury and underlying mechanism in rats
    Authors: J Meng, J Tian, Y Zhao, C Li, Y Yi, Y Zhang, J Han, L Wang, C Pan, S Liu, C Liu, F Wang, X Tang, D Wang, S Qin, A Liang
    Heliyon, 2023;9(4):e15333.
    Species: Rat
    Sample Types: Tissue Homogenates
  8. Lactate attenuates astrocytic inflammation by inhibiting ubiquitination and degradation of NDRG2 under oxygen-glucose deprivation conditions
    Authors: J Xu, T Ji, G Li, H Zhang, Y Zheng, M Li, J Ma, Y Li, G Chi
    Journal of Neuroinflammation, 2022-12-26;19(1):314.
    Species: Rat
    Sample Types: Cell Culture Supernates
  9. Acute postoperative pain and dorsal root ganglia transcriptomic signatures following total knee arthroplasty (TKA) in rats: An experimental study
    Authors: DE Komatsu, SMZ Uddin, C Gordon, MP Kanjiya, D Bogdan, J Achonu, A DiBua, H Iftikhar, A Ackermann, RJ Shah, J Shieh, AB Bialkowska, M Kaczocha
    PLoS ONE, 2022-12-06;17(12):e0278632.
    Species: Rat
    Sample Types: Serum
  10. A Comparative Study of Two Models of Intraluminal Filament Middle Cerebral Artery Occlusion in Rats: Long-Lasting Accumulation of Corticosterone and Interleukins in the Hippocampus and Frontal Cortex in Koizumi Model
    Authors: MV Onufriev, MY Stepaniche, YV Moiseeva, MY Zhanina, OA Nedogreeva, PA Kostryukov, NA Lazareva, NV Gulyaeva
    Biomedicines, 2022-12-02;10(12):.
    Species: Rat
    Sample Types: Serum
  11. Black Garlic and Thiosulfinate-Enriched Extracts as Adjuvants to Ceftriaxone Treatment in a Rat Peritonitis Model of Sepsis
    Authors: FJ Redondo-Ca, N Bejarano-R, V Baladrón, O Montenegro, LA Gómez, R Velasco, N Villasanti, S Illescas, MT Franco-Ser, I Gracia, JF Rodríguez, JR Muñoz-Rodr, JM Pérez-Orti
    Biomedicines, 2022-12-01;10(12):.
    Species: Rat
    Sample Types: Serum
  12. Reducing brain TACE activity improves neuroinflammation and cardiac function in heart failure rats
    Authors: Y Yu, B Xue, NM Irfan, T Beltz, RM Weiss, AK Johnson, RB Felder, SG Wei
    Frontiers in Physiology, 2022-11-09;13(0):1052304.
    Species: Rat
    Sample Types: CSF
  13. Anti-Inflammatory Protein Isolated from Tamarind Promotes Better Histological Aspects in the Intestine Regardless of the Improvement of Intestinal Permeability in a Preclinical Study of Diet-Induced Obesity
    Authors: MSR Lima, C Gonçalves, MD Neto, MH Macedo, JLC Queiroz, VC da Silva, IS Costa, CDS Camillo, PPA Santos, AAM Lima, L Pastrana, BLL Maciel, AHA Morais
    Nutrients, 2022-11-04;14(21):.
    Species: Rat
    Sample Types: Plasma
  14. MicroRNA-25-5p negatively regulates TXNIP expression and relieves inflammatory responses of brain induced by lipopolysaccharide
    Authors: J Wang, Z Ye, Y Chen, X Qiao, Y Jin
    Scientific Reports, 2022-10-26;12(1):17915.
    Species: Rat
    Sample Types: Plasma
  15. DUSP8/TAK1 signaling mediates neuropathic pain through regulating neuroinflammation and neuron death in a spinal nerve ligation (SNL) rat model
    Authors: C Liao, H Zhou, H Chen, G Cheng, S Li, F Ma, X Yang, B Xie, W Zhang
    International immunopharmacology, 2022-10-21;113(0):109284.
    Species: Rat
    Sample Types: Cell Culture Supernates
  16. Sacubitril/valsartan (LCZ696) ameliorates hyperthyroid-induced cardiac hypertrophy in male rats through modulation of miR-377, let-7 b, autophagy, and fibrotic signaling pathways
    Authors: T Khamis, AE Alsemeh, DM Abdullah
    Scientific Reports, 2022-08-27;12(1):14654.
    Species: Rat
    Sample Types: Serum
  17. Rhabdomyolysis-induced acute kidney injury and concomitant apoptosis induction via ROS-mediated ER stress is efficaciously counteracted by epigallocatechin gallate
    Authors: SN Chang, M Haroon, DK Dey, SC Kang
    The Journal of nutritional biochemistry, 2022-08-24;0(0):109134.
    Species: Rat
    Sample Types: Tissue Homogenates
  18. Anti-inflammatory clearance of amyloid-beta by a chimeric Gas6 fusion protein
    Authors: H Jung, SY Lee, S Lim, HR Choi, Y Choi, M Kim, S Kim, Y Lee, KH Han, WS Chung, CH Kim
    Nature Medicine, 2022-08-04;0(0):.
    Species: Rat
    Sample Types: Cell Culture Supernates
  19. Transient neuroinflammation following surgery contributes to long-lasting cognitive decline in elderly rats via dysfunction of synaptic NMDA receptor
    Authors: B Chen, G Qin, J Xiao, X Deng, A Lin, H Liu
    Journal of Neuroinflammation, 2022-07-13;19(1):181.
    Species: Rat
    Sample Types: Serum
  20. Neuroprotective Effect of Bcl-2 on Lipopolysaccharide-Induced Neuroinflammation in Cortical Neural Stem Cells
    Authors: SY Park, JS Han
    International Journal of Molecular Sciences, 2022-06-07;23(12):.
    Species: Rat
    Sample Types: Cell Culture Supernates
  21. Aerobic exercise training combined or not with okra consumption as a strategy to prevent kidney changes caused by metabolic syndrome in Zucker rats
    Authors: MM da Silva, MFP Gomes, EOC de Moura, MM Veras, MC Kubota, AP Takano, ACC Dos Santos, CGDR José, GADS Souza, NM Cardoso, D Estadella, RH Lambertucc, A Medeiros
    PLoS ONE, 2022-06-03;17(6):e0269418.
    Species: Rat
    Sample Types: Tissue Homogenates
  22. Melatonin and zinc supplements with physical and mental activities subside neurodegeneration and hepatorenal injury induced by aluminum chloride in rats: Inclusion of GSK-3beta-Wnt/beta-catenin signaling pathway
    Authors: K Abu-Elfotu, FH Hussein, AN Abbas, MD Al-Rekabi, SS Barghash, SS Zaghlool, SZ El-Emam
    Neurotoxicology, 2022-05-05;91(0):69-83.
    Species: Rat
    Sample Types: Tissue Homogenates
  23. H3K9me2 regulation of BDNF expression via G9a partakes in the progression of heart failure
    Authors: F Yan, Z Chen, W Cui
    BMC cardiovascular disorders, 2022-04-19;22(1):182.
    Species: Rat
    Sample Types: Serum
  24. PPARalpha contributes to the therapeutic effect of hydrogen gas against sepsis-associated encephalopathy with the regulation to the CREB-BDNF signaling pathway and hippocampal neuron plasticity-related gene expression
    Authors: Y Bai, Q Han, B Dong, H Lin, Y Jiang, X Zhang, H Chen, Y Yu
    Brain research bulletin, 2022-03-30;184(0):56-67.
    Species: Mouse
    Sample Types: Tissue Homogenates
  25. Piceatannol suppresses inflammation and promotes apoptosis in rheumatoid arthritis?fibroblast?like synoviocytes by inhibiting the NF?kappaB and MAPK signaling pathways
    Authors: X Gao, X Kang, H Lu, E Xue, R Chen, J Pan, J Ma
    Molecular Medicine Reports, 2022-03-24;25(5):.
    Species: Rat
    Sample Types: Serum
  26. Vitamin C Improves the Outcomes of Cardiopulmonary Resuscitation and Alters Shedding of Syndecan-1 and p38/MAPK Phosphorylation in a Rat Model
    Authors: Y Xiao, C Su, G Zhang, L Liang, T Jin, J Bradley, JP Ornato, W Tang
    Journal of the American Heart Association, 2022-03-15;0(0):e023787.
    Species: Rat
    Sample Types: Serum
  27. Repeated glucose spikes and insulin resistance synergistically deteriorate endothelial function and bardoxolone methyl ameliorates endothelial dysfunction
    Authors: K Ogiso, SC Shayo, S Kawade, H Hashiguchi, T Deguchi, Y Nishio
    PLoS ONE, 2022-01-24;17(1):e0263080.
    Species: Rat
    Sample Types: Serum
  28. Targeting inflammation, autophagy, and apoptosis by troxerutin attenuates methotrexate-induced renal injury in rats
    Authors: HH Arab, SA Abd El-Aal, AH Eid, EA Arafa, AM Mahmoud, AM Ashour
    International immunopharmacology, 2021-12-23;103(0):108284.
    Species: Rat
    Sample Types: Tissue Homogenates
  29. A Comparative Study of Koizumi and Longa Methods of Intraluminal Filament Middle Cerebral Artery Occlusion in Rats: Early Corticosterone and Inflammatory Response in the Hippocampus and Frontal Cortex
    Authors: MV Onufriev, YV Moiseeva, MY Zhanina, NA Lazareva, NV Gulyaeva
    International Journal of Molecular Sciences, 2021-12-17;22(24):.
    Species: Rat
    Sample Types: Serum
  30. Essential Fatty Acids and Their Metabolites in the Pathobiology of Inflammation and Its Resolution
    Authors: UN Das
    Biomolecules, 2021-12-14;11(12):.
    Species: Rat
    Sample Types: Plasma
  31. Study of the Role of the Tyrosine Kinase Receptor MerTK in the Development of Kidney Ischemia-Reperfusion Injury in RCS Rats
    Authors: T Pelé, S Giraud, S Joffrion, V Ameteau, A Delwail, JM Goujon, L Macchi, T Hauet, F Dkhissi, O Benzakour
    International Journal of Molecular Sciences, 2021-11-09;22(22):.
    Species: Rat
    Sample Types: Plasma
  32. Protective effects of endothelial progenitor cell microvesicles on Ang�II?induced rat kidney cell injury
    Authors: Y Song, Z Bai, Y Zhang, J Chen, M Chen, Y Zhang, X Zhang, H Mai, B Wang, Y Lin, S Gu
    Molecular Medicine Reports, 2021-11-05;25(1):.
    Species: Rat
    Sample Types: Cell Culture Supernates
  33. Endogenous tRNA-derived small RNA (tRF3-Thr-AGT) inhibits ZBP1/NLRP3 pathway-mediated cell pyroptosis to attenuate acute pancreatitis (AP)
    Authors: B Sun, Z Chen, Q Chi, Y Zhang, B Gao
    Journal of Cellular and Molecular Medicine, 2021-10-13;0(0):.
    Species: Rat
    Sample Types: Cell Culture Supernates
  34. Loganin Ameliorates Painful Diabetic Neuropathy by Modulating Oxidative Stress, Inflammation and Insulin Sensitivity in Streptozotocin-Nicotinamide-Induced Diabetic Rats
    Authors: YC Cheng, YM Chiu, ZK Dai, BN Wu
    Cells, 2021-10-08;10(10):.
    Species: Rat
    Sample Types: Plasma
  35. Renoprotection Induced by Aerobic Training Is Dependent on Nitric Oxide Bioavailability in Obese Zucker Rats
    Authors: RVP Neves, HL Corrêa, IV de Sousa N, MK Souza, F Costa, AS Haro, LA Deus, AL Reis, HG Simões, RV Andrade, CO Assumpção, W Stone, J Prestes, EC Vieira, R de Cássia, V Cruzat, TS Rosa
    Oxidative Medicine and Cellular Longevity, 2021-09-28;2021(0):3683796.
    Species: Rat
    Sample Types: Tissue Homogenates
  36. Hydrogen Sulfide Reduces Ischemia and Reperfusion Injury in Neuronal Cells in a Dose- and Time-Dependent Manner
    Authors: S Scheid, M Goeller, W Baar, J Wollborn, H Buerkle, G Schlunck, W Lagrèze, U Goebel, F Ulbrich
    International Journal of Molecular Sciences, 2021-09-18;22(18):.
    Species: Rat
    Sample Types: Serum
  37. Intervention of Gastrodin in Type 2 Diabetes Mellitus and Its Mechanism
    Authors: Y Bai, K Mo, G Wang, W Chen, W Zhang, Y Guo, Z Sun
    Frontiers in Pharmacology, 2021-09-16;12(0):710722.
    Species: Rat
    Sample Types: Serum
  38. Balance of Drug Residence and Diffusion in Lacrimal Fluid Determine Ocular Bioavailability in In Situ Gels Incorporating Tranilast Nanoparticles
    Authors: M Minami, H Otake, Y Nakazawa, N Okamoto, N Yamamoto, H Sasaki, N Nagai
    Pharmaceutics, 2021-09-08;13(9):.
    Species: Rat
    Sample Types: Tissue Homogenates
  39. GPER and IGF-1R mediate the anti-inflammatory effect of genistein against lipopolysaccharide (LPS)-induced nigrostriatal injury in rats
    Authors: ZR Du, Y Gu, XM Xie, M Zhang, GY Jiang, WF Chen
    The Journal of steroid biochemistry and molecular biology, 2021-08-31;214(0):105989.
    Species: Rat
    Sample Types: Tissue Homogenates
  40. Acute myocardial injury secondary to severe acute liver failure: A retrospective analysis supported by animal data
    Authors: M Uhlig, M Hein, MA Habigt, RH Tolba, T Braunschwe, MJ Helmedag, U Klinge, A Koch, C Trautwein, M Mechelinck
    PLoS ONE, 2021-08-30;16(8):e0256790.
    Species: Rat
    Sample Types: Plasma
  41. Acute Inflammatory Response in Osteoporotic Fracture Healing Augmented with Mechanical Stimulation is Regulated In Vivo through the p38-MAPK Pathway
    Authors: SKH Chow, C Cui, KYK Cheng, YN Chim, J Wang, CHW Wong, KW Ng, RMY Wong, WH Cheung
    International Journal of Molecular Sciences, 2021-08-13;22(16):.
    Species: Rat
    Sample Types: Serum
  42. Suppression of Inflammation-Associated Kidney Damage Post-Transplant Using the New PrC-210 Free Radical Scavenger in Rats
    Authors: TR Goesch, NA Wilson, W Zeng, BM Verhoven, W Zhong, MM Coumbe Git, WE Fahl
    Biomolecules, 2021-07-19;11(7):.
    Species: Rat
    Sample Types: Plasma
  43. L. Cucurbita pepo Alleviates Chronic Unpredictable Mild Stress via Modulation of Apoptosis, Neurogenesis, and Gliosis in Rat Hippocampus
    Authors: N Ayuob, SA Shaker, E Hawuit, NS Al-Abbas, NA Shaer, S Al Jaouni, MR Mahdi
    Oxidative Medicine and Cellular Longevity, 2021-07-10;2021(0):6662649.
    Species: Rat
    Sample Types: Serum
  44. Can selenium-enriched spirulina supplementation ameliorate sepsis outcomes in selenium-deficient animals?
    Authors: T Castel, M Theron, K Pichavant-, A Guernec, A Joublin-De, B Gueguen, K Leon
    Physiological Reports, 2021-07-01;9(14):e14933.
    Species: Rat
    Sample Types: Plasma
  45. Prenatal Hyperhomocysteinemia Induces Glial Activation and Alters Neuroinflammatory Marker Expression in Infant Rat Hippocampus
    Authors: AD Shcherbits, DS Vasilev, YP Milyutina, NL Tumanova, AV Mikhel, IV Zalozniaia, AV Arutjunyan
    Cells, 2021-06-18;10(6):.
    Species: Rat
    Sample Types: Tissue Homogenates
  46. Co-infection by Salmonella enterica subsp. Enterica serovar typhimurium and Entamoeba dispar pathogenic strains enhances colitis and the expression of amoebic virulence factors
    Authors: FM Silva Oliv, A Claúdia de, S Henrique d, LO Prata, MA Junior, CA Vilela da, GH Campolina-, M Lorenzo de, CA Oliveira, E Neumann, ÁC Nunes, MA Gomes, MV Caliari
    Microbial pathogenesis, 2021-06-12;158(0):105010.
    Species: Rat
    Sample Types: Plasma
  47. Down-regulation of SNHG16 alleviates the acute lung injury in sepsis rats through miR-128-3p/HMGB3 axis
    Authors: J Sun, K Xin, C Leng, J Ge
    BMC pulmonary medicine, 2021-06-06;21(1):191.
    Species: Rat
    Sample Types: Tissue Homogenates
  48. Neuroprotective Effects of VEGF-A Nanofiber Membrane and FAAH Inhibitor URB597 Against Oxygen-Glucose Deprivation-Induced Ischemic Neuronal Injury
    Authors: DP Wang, KY Jin, P Zhao, Q Lin, K Kang, J Hai
    International Journal of Nanomedicine, 2021-05-27;16(0):3661-3678.
    Species: Rat
    Sample Types: Cell Culture Supernates
  49. MiR-128-3p alleviates TNBS-induced colitis through inactivating TRAF6/NF-&kappaB signaling pathway in rats
    Authors: LL Huo, ZR Sun
    The Kaohsiung journal of medical sciences, 2021-05-27;0(0):.
    Species: Rat
    Sample Types: Tissue Homogenates
  50. Non-alcoholic fatty liver disease is associated with bacterial translocation and a higher inflammation response in psoriatic patients
    Authors: I Belinchón-, P Bellot, D Romero-Pér, I Herraiz-Ro, F Marco, R Frances, JM Ramos-Rinc
    Scientific Reports, 2021-04-21;11(1):8593.
    Species: Rat
    Sample Types: Serum
  51. Phgdh serves a protective role in Il?1&beta induced chondrocyte inflammation and oxidative?stress damage
    Authors: H Huang, K Liu, H Ou, X Qian, J Wan
    Molecular Medicine Reports, 2021-04-13;23(6):.
    Species: Rat
    Sample Types: Cell Culture Supernates
  52. Spirulina platensis and its ingredient biopterin glucoside improved insulin sensitivity in non-alcoholic steatohepatitis model
    Authors: Y Fujihara, Y Kodo, SI Miyoshi, R Watanabe, H Toyoda, M Mankura, H Kabuto, F Takayama
    Journal of Clinical Biochemistry and Nutrition, 2021-03-25;69(2):151-157.
    Species: Rat
    Sample Types: Plasma
  53. Protective effects of curcumin against rat intestinal inflammation?related motility disorders
    Authors: Y Yao, R Luo, S Xiong, C Zhang, Y Zhang
    Molecular Medicine Reports, 2021-03-24;23(5):.
    Species: Rat
    Sample Types: Serum
  54. Precisely Fabricated Sulpiride-Loaded Nanolipospheres with Ameliorated Oral Bioavailability and Antidepressant Activity
    Authors: SM Mohyeldin, WM Samy, D Ragab, DA Abdelmonsi, RG Aly, NA Elgindy
    International Journal of Nanomedicine, 2021-03-09;16(0):2013-2044.
    Species: Rat
    Sample Types: Tissue Homogenates
  55. Vagus nerve stimulation ameliorates L-NAME-induced preeclampsia-like symptoms in rats through inhibition of the inflammatory response
    Authors: L Zheng, R Tang, L Shi, M Zhong, Z Zhou
    BMC pregnancy and childbirth, 2021-03-04;21(1):177.
    Species: Rat
    Sample Types: Serum
  56. Antioxidative Capacity of Liver- and Adipose-Derived Mesenchymal Stem Cell-Conditioned Media and Their Applicability in Treatment of Type 2 Diabetic Rats
    Authors: MM Elshemy, M Asem, KS Allemailem, K Uto, M Ebara, A Nabil
    Oxidative Medicine and Cellular Longevity, 2021-02-02;2021(0):8833467.
    Species: Rat
    Sample Types: Serum
  57. Sericin-chitosan-glycosaminoglycans hydrogels incorporated with growth factors for in vitro and in vivo skin repair
    Authors: S Sapru, S Das, M Mandal, AK Ghosh, SC Kundu
    Carbohydrate polymers, 2021-01-29;258(0):117717.
    Species: Rat
    Sample Types: Serum
  58. Docosahexaenoic fatty acid reduces the pro-inflammatory response induced by IL-1&beta in astrocytes through inhibition of NF-&kappaB and AP-1 transcription factor activation
    Authors: E Zgórzy?ska, D Stulczewsk, B Dziedzic, KP Su, A Walczewska
    Bmc Neuroscience, 2021-01-27;22(1):4.
    Species: Rat
    Sample Types: Cell Culture Supernates
  59. Cognitive effects of the GSK-3 inhibitor "lithium" in LPS/chronic mild stress rat model of depression: Hippocampal and cortical neuroinflammation and tauopathy
    Authors: MA Ebeid, MZ Habib, AM Mohamed, YE Faramawy, SST Saad, OA El-Kharash, HME Magdoub, HA Abd-Alkhal, S Aboul-Foto, AM Abdel-Tawa
    Neurotoxicology, 2021-01-06;83(0):77-88.
    Species: Rat
    Sample Types: Tissue Homogenates
  60. Potential of an Interorgan Network Mediated by Toxic Advanced Glycation End-Products in a Rat Model
    Authors: S Inoue, T Takata, Y Nakazawa, Y Nakamura, X Guo, S Yamada, Y Ishigaki, M Takeuchi, K Miyazawa
    Nutrients, 2020-12-29;13(1):.
    Species: Rat
    Sample Types: Serum
  61. Isoflurane reduces septic neuron injury by HO?1?mediated abatement of inflammation and apoptosis
    Authors: L Zhang, X Zhang, T Wu, X Pan, Z Wang
    Molecular Medicine Reports, 2020-12-23;23(2):.
    Species: Mouse
    Sample Types: Serum
  62. The antihypertensive agent hydralazine reduced extracellular matrix synthesis and liver fibrosis in nonalcoholic steatohepatitis exacerbated by hypertension
    Authors: Y Yuan, H Naito, K Kitamori, S Hashimoto, T Asano, T Nakajima
    PLoS ONE, 2020-12-14;15(12):e0243846.
    Species: Rat
    Sample Types: Serum
  63. Angiopoietin-2 is released during anaphylactic hypotension in anesthetized and unanesthetized rats
    Authors: T Zhang, T Shibamoto, M Tanida, M Taniguchi, Y Kuda, W Yang, Y Kurata
    PLoS ONE, 2020-11-17;15(11):e0242026.
    Species: Rat
    Sample Types: Plasma
  64. Sex Differences in Vagus Nerve Stimulation Effects on Rat Cardiovascular and Immune Systems
    Authors: F Yaghouby, K Jang, U Hoang, S Asgari, S Vasudevan
    Front Neurosci, 2020-11-06;14(0):560668.
    Species: Rat
    Sample Types: Plasma
  65. SNHG16 aggravates chronic constriction injury-induced neuropathic pain in rats via binding with miR-124-3p and miR-141-3p to upregulate JAG1
    Authors: H Li, L Fan, Y Zhang, Y Cao, X Liu
    Brain Res Bull, 2020-10-10;165(0):228-237.
    Species: Rat
    Sample Types: Cell Culture Supernates
  66. Anticolitic Effect of Berberine in Rat Experimental Model: Impact of PGE2/p38 MAPK Pathways
    Authors: L Jia, K Xue, J Liu, OA Habotta, L Hu, AE Abdel Mone
    Mediators Inflamm, 2020-09-29;2020(0):9419085.
    Species: Rat
    Sample Types: Cell Culture Supernates
  67. Selenium Nanoparticles Pre-Treatment Reverse Behavioral, Oxidative Damage, Neuronal Loss and Neurochemical Alterations in Pentylenetetrazole-Induced Epileptic Seizures in Mice
    Authors: X Yuan, Z Fu, P Ji, L Guo, AO Al-Ghamdy, A Alkandiri, OA Habotta, AE Abdel Mone, RB Kassab
    Int J Nanomedicine, 2020-08-24;15(0):6339-6353.
    Species: Mouse
    Sample Types: Tissue Homogenates
  68. Methane Ameliorates Lipopolysaccharide-Induced Acute Orchitis by Anti-inflammatory, Antioxidative, and Antiapoptotic Effects via Regulation of the PK2/PKR1 Pathway
    Authors: C Huang, W Zhang, A Sun, X Zhang, J Guo, R Ji, L Qiao, X Sun, D Zhao
    Oxid Med Cell Longev, 2020-08-18;2020(0):7075836.
    Species: Rat
    Sample Types: Plasma
  69. N?acetyl cysteine inhibits the lipopolysaccharide?induced inflammatory response in bone marrow mesenchymal stem cells by suppressing the TXNIP/NLRP3/IL?1&beta signaling pathway
    Authors: X Wang, M Jiang, X He, B Zhang, W Peng, L Guo
    Molecular Medicine Reports, 2020-08-13;0(0):.
    Species: Rat
    Sample Types: Cell Culture Supernates
  70. Inhibitor of RAGE and glucose?induced inflammation in bone marrow mesenchymal stem cells: Effect and mechanism of action
    Authors: M Jiang, X Wang, P Wang, W Peng, B Zhang, L Guo
    Molecular Medicine Reports, 2020-08-07;0(0):.
    Species: Rat
    Sample Types: Cell Culture Supernates
  71. Prevention of Oxygen-Induced Inflammatory Lung Injury by Caffeine in Neonatal Rats
    Authors: S Endesfelde, E Strau beta, I Bendix, T Schmitz, C Bührer
    Oxid Med Cell Longev, 2020-08-07;2020(0):3840124.
    Species: Rat
    Sample Types: Tissue Homogenates
  72. Effects of dietary fiber on vascular calcification by repetitive diet-induced fluctuations in plasma phosphorus in early-stage chronic kidney disease rats
    Authors: M Tani, S Tanaka, K Takamiya, Y Kato, G Harata, F He, M Sakaue, M Ito
    Journal of Clinical Biochemistry and Nutrition, 2020-08-06;67(3):283-289.
    Species: Rat
    Sample Types: Plasma
  73. Inhibition of HtrA2 alleviates inflammatory response and cell apoptosis in lipopolysaccharide?induced acute pneumonia in rats
    Authors: X Wang
    Molecular Medicine Reports, 2020-08-04;0(0):.
    Species: Rat
    Sample Types: Cell Culture Supernates
  74. Tetramethylpyrazine alleviates acute kidney injury by inhibiting NLRP3/HIF?1&alpha and apoptosis
    Authors: W Sun, A Li, Z Wang, X Sun, M Dong, F Qi, L Wang, Y Zhang, P Du
    Molecular Medicine Reports, 2020-07-28;0(0):.
    Species: Rat
    Sample Types: Serum
  75. Histamine 2/3 receptor agonists alleviate perioperative neurocognitive disorders by inhibiting microglia activation through the PI3K/AKT/FoxO1 pathway in aged rats
    Authors: YN Chen, HH Sha, YW Wang, Q Zhou, P Bhuiyan, NN Li, YN Qian, HQ Dong
    J Neuroinflammation, 2020-07-22;17(1):217.
    Species: Rat
    Sample Types: Cell Culture Supernates
  76. Prophylactic therapy with human amniotic fluid stem cells improved survival in a rat model of lipopolysaccharide-induced neonatal sepsis through immunomodulation via aggregates with peritoneal macrophages
    Authors: Y Sato, D Ochiai, Y Abe, H Masuda, M Fukutake, S Ikenoue, Y Kasuga, M Shimoda, Y Kanai, M Tanaka
    Stem Cell Res Ther, 2020-07-20;11(1):300.
    Species: Rat
    Sample Types: Serum
  77. Dexmedetomidine alleviates blunt chest trauma and hemorrhagic shock?resuscitation?induced acute lung injury through inhibiting the NLRP3 inflammasome
    Authors: T Ming, M Yuan, Q Kong, Q Huang, Z Xia, X Wu
    Mol Med Rep, 2020-07-10;22(3):2507-2515.
    Species: Rat
    Sample Types: Serum
  78. HPLC-PDA-MS/MS profiling of secondary metabolites from Opuntia ficus-indica cladode, peel and fruit pulp extracts and their antioxidant, neuroprotective effect in rats with aluminum chloride induced neurotoxicity
    Authors: SS El-Hawary, M Sobeh, WK Badr, MAO Abdelfatta, ZY Ali, ME El-Tantawy, MA Rabeh, M Wink
    Saudi J Biol Sci, 2020-07-09;27(10):2829-2838.
    Species: Rat
    Sample Types: Tissue Homogenates
  79. Skeletal muscle dysregulation in rheumatoid arthritis: Metabolic and molecular markers in a rodent model and patients
    Authors: N Casanova-V, D Constantin, A Filer, RS Hardy, PL Greenhaff, V Chapman
    PLoS ONE, 2020-07-07;15(7):e0235702.
    Species: Rat
    Sample Types: Plasam
  80. Comparison of the effect of membrane sizes and fibre arrangements of two membrane oxygenators on the inflammatory response, oxygenation and decarboxylation in a rat model of extracorporeal membrane oxygenation
    Authors: F Edinger, E Schneck, C Schulte, J Gehron, S Mueller, M Sander, C Koch
    BMC Cardiovasc Disord, 2020-06-15;20(1):294.
    Species: Rat
    Sample Types: Plasma
  81. Xanthan gum protects temporomandibular chondrocytes from IL?1&beta through Pin1/NF?&kappaB signaling pathway
    Authors: F Yuan, JL Xie, KY Liu, JL Shan, YG Sun, WG Ying
    Mol Med Rep, 2020-06-15;22(2):1129-1136.
    Species: Rat
    Sample Types: Cell Culture Supernates
  82. Activation of FoxO1/SIRT1/RANKL/OPG pathway may underlie the therapeutic effects of resveratrol on aging-dependent male osteoporosis
    Authors: O Ameen, RI Yassien, YM Naguib
    BMC Musculoskelet Disord, 2020-06-12;21(1):375.
    Species: Rat
    Sample Types: Serum
  83. Long non-coding RNA ANRIL knockdown suppresses apoptosis and pro-inflammatory cytokines while enhancing neurite outgrowth via binding microRNA-125a in a cellular model of Alzheimer's disease
    Authors: B Zhou, L Li, X Qiu, J Wu, L Xu, W Shao
    Mol Med Rep, 2020-06-02;22(2):1489-1497.
    Species: Rat
    Sample Types: Cell Culture Supernates
  84. Protective effect of Chresta martii extract on the zymosan-induced temporomandibular joint arthritis in rats
    Authors: D Rocha do V, MM Bezerra, FI Fernandes, CA Nobre, SC Teixeira, JC Lemos, KM Alves Pere, V de Paulo T, AA Rodrigues, E de Sousa F, M Bernadete, HV Chaves
    J Oral Biol Craniofac Res, 2020-05-28;10(3):276-280.
    Species: Rat
    Sample Types: Cell Lysates
  85. Red Beetroot Extract Abrogates Chlorpyrifos-Induced Cortical Damage in Rats
    Authors: G Albasher, AS Alsaleh, N Alkubaisi, S Alfarraj, S Alkahtani, M Farhood, N Alotibi, R Almeer
    Oxid Med Cell Longev, 2020-03-09;2020(0):2963020.
    Species: Rat
    Sample Types: Tissue Homogenates
  86. Therapeutic Effects of Lithospermate B Complexed with Mg2+ or Zn2+ on Metabolic Syndrome Induced in Rats Fed with High-Fat Diet
    Authors: SK Hsieh, NH Lin, YJ Chen, MR Lee, WY Chen, JTC Tzen
    Molecules, 2020-02-22;25(4):.
    Species: Rat
    Sample Types: Whole Blood
  87. Effects of repetitive diet-induced fluctuations in plasma phosphorus on vascular calcification and inflammation in rats with early-stage chronic kidney disease
    Authors: M Tani, S Tanaka, K Takamiya, M Sakaue, M Ito
    J Clin Biochem Nutr, 2020-02-08;66(2):139-145.
    Species: Rat
    Sample Types: Plasma
  88. Comparison of the acute toxicity, analgesic and anti-inflammatory activities and chemical composition changes in Rhizoma anemones Raddeanae caused by vinegar processing
    Authors: SS Wang, SY Zhou, XY Xie, L Zhao, Y Fu, GZ Cai, JY Gong
    BMC Complement Med Ther, 2020-01-15;20(1):7.
    Species: Rat
    Sample Types: Serum
  89. Identification of microRNA?363?3p as an essential regulator of chondrocyte apoptosis in osteoarthritis by targeting NRF1 through the p53?signaling pathway
    Authors: M Zhang, Z Wang, B Li, F Sun, A Chen, M Gong
    Mol Med Rep, 2020-01-14;21(3):1077-1088.
    Species: Rat
    Sample Types: Synovial Fluid
  90. Oxidative Stress Parameters in the Liver of Growing Male Rats Receiving Various Alcoholic Beverages
    Authors: A Ko?ota, D G??bska, M Oczkowski, J Gromadzka-
    Nutrients, 2020-01-06;12(1):.
    Species: Rat
    Sample Types: Tissue Homogenates
  91. Nephroprotective Role of Beta vulgaris L. Root Extract against Chlorpyrifos-Induced Renal Injury in Rats
    Authors: G Albasher, R Almeer, S Alarifi, S Alkhtani, M Farhood, FO Al-Otibi, N Alkubaisi, H Rizwana
    Evid Based Complement Alternat Med, 2019-11-22;2019(0):3595761.
    Species: Rat
    Sample Types: Tissue Homogenates
  92. Hemorrhagic Shock Sensitized the Diaphragm to Ventilator-Induced Dysfunction through the Activation of IL-6/JAK/STAT Signaling-Mediated Autophagy in Rats
    Authors: LJ Zhang, SZ Ni, XL Zhou, Y Zhao
    Mediators Inflamm., 2019-11-14;2019(0):3738409.
    Species: Rat
    Sample Types: Tissue Homogenates
  93. Neutrophil activation causes tumor regression in Walker 256 tumor-bearing rats
    Authors: WMT Kuwabara, J Andrade-Si, JNB Pereira, JH Scialfa, J Cipolla-Ne
    Sci Rep, 2019-11-11;9(1):16524.
    Species: Rat
    Sample Types: BALF
  94. CoQ10 ameliorates monosodium glutamate-induced alteration in detrusor activity and responsiveness in rats via anti-inflammatory, anti-oxidant and channel inhibiting mechanisms
    Authors: DF El Agamy, YM Naguib
    BMC Urol, 2019-10-28;19(1):103.
    Species: Rat
    Sample Types: Serum
  95. Interactive effects of maternal and weaning high linoleic acid intake on hepatic lipid metabolism, oxylipins profile and hepatic steatosis in offspring
    Authors: J Marchix, D Catheline, C Duby, N Monthéan-B, F Boissel, F Pédrono, G Boudry, P Legrand
    J. Nutr. Biochem., 2019-10-26;75(0):108241.
    Species: Rat
    Sample Types: Plasma
  96. IL?1beta increases the expression of inflammatory factors in synovial fluid?derived fibroblast?like synoviocytes via activation of the NF?kappaB?mediated ERK?STAT1 signaling pathway
    Authors: J Yang, J Wang, X Liang, H Zhao, J Lu, Q Ma, B Jing, F Tian
    Mol Med Rep, 2019-10-21;0(0):.
    Species: Rat
    Sample Types: Whole Blood
  97. Low-Energy Extracorporeal Shock Wave Ameliorates Streptozotocin Induced Diabetes and Promotes Pancreatic Beta Cells Regeneration in a Rat Model
    Authors: CC Hsiao, CC Lin, YS Hou, JY Ko, CJ Wang
    Int J Mol Sci, 2019-10-05;20(19):.
    Species: Rat
    Sample Types: Tissue Lysates
  98. Human mesenchymal stromal cells ameliorate complement induced inflammatory cascade and improve renal functions in a rat model of ischemia-reperfusion induced acute kidney injury
    Authors: S Zilberman-, R Abu-Hamad, R Zarura, M Sova, Y Hachmo, M Stark, S Neuman, S Slavin, S Efrati
    PLoS ONE, 2019-09-12;14(9):e0222354.
    Species: Rat
    Sample Types: Serum
  99. Ameliorative Effect of Beta vulgaris Root Extract on Chlorpyrifos-Induced Oxidative Stress, Inflammation and Liver Injury in Rats
    Authors: G Albasher, R Almeer, FO Al-Otibi, N Al-Kubaisi, AM Mahmoud
    Biomolecules, 2019-07-07;9(7):.
    Species: Rat
    Sample Types: Tissue Homogenates
  100. Rice Porridge Containing Welsh Onion Root Water Extract Alleviates Osteoarthritis-Related Pain Behaviors, Glucose Levels, and Bone Metabolism in Osteoarthritis-Induced Ovariectomized Rats
    Authors: HJ Yang, MJ Kim, JY Qiu, T Zhang, X Wu, DJ Jang, S Park
    Nutrients, 2019-06-30;11(7):.
    Species: Rat
    Sample Types: Serum
  101. Sex-specific maternofetal innate immune responses triggered by group B Streptococci
    Authors: MJ Allard, A Giraud, M Segura, G Sebire
    Sci Rep, 2019-06-13;9(1):8587.
    Species: Rat
    Sample Types: Protein
  102. Atractylenolide III Attenuates Muscle Wasting in Chronic Kidney Disease via the Oxidative Stress-Mediated PI3K/AKT/mTOR Pathway
    Authors: M Wang, R Hu, Y Wang, L Liu, H You, J Zhang, X Wu, T Pei, F Wang, L Lu, W Xiao, L Wei
    Oxid Med Cell Longev, 2019-04-18;2019(0):1875471.
    Species: Rat
    Sample Types: Serum
  103. Exosomes derived from mangiferin?stimulated perivascular adipose tissue ameliorate endothelial dysfunction
    Authors: Q Zhao, J Yang, B Liu, F Huang, Y Li
    Mol Med Rep, 2019-04-04;0(0):.
    Species: Rat
    Sample Types: Cell Culture Supernates
  104. Neuroinflammation induced by the peptide amyloid-? (25-35) increase the presence of galectin-3 in astrocytes and microglia and impairs spatial memory
    Authors: E Ramírez, C Sánchez-Ma, MA Mayoral, L Mendieta, V Alatriste, A Patricio-M, ID Limón
    Neuropeptides, 2019-02-14;0(0):.
    Species: Rat
    Sample Types: Tissue Homogenates
  105. Elevated pulmonary arterial pressure in Zucker diabetic fatty rats
    Authors: D Morales-Ca, M Callejo, B Barreira, G Mondejar-P, S Esquivel-R, S Ramos, MÁ Martín, A Cogolludo, L Moreno, F Perez-Vizc
    PLoS ONE, 2019-01-28;14(1):e0211281.
    Species: Rat
    Sample Types: Serum
  106. Hepatokine ?1-Microglobulin Signaling Exacerbates Inflammation and Disturbs Fibrotic Repair in Mouse Myocardial Infarction
    Authors: D Hakuno, M Kimura, S Ito, J Satoh, Y Nakashima, T Horie, Y Kuwabara, M Nishiga, Y Ide, O Baba, H Nishi, T Nakao, T Nishino, F Nakazeki, S Koyama, R Hanada, RR Randolph, J Endo, T Kimura, K Ono
    Sci Rep, 2018-11-13;8(1):16749.
    Species: Rat
    Sample Types: Cell Culture Supernates
  107. Valproate reduces neuroinflammation and neuronal death in a rat chronic constriction injury model
    Authors: JY Chen, LW Chu, KI Cheng, SL Hsieh, YS Juan, BN Wu
    Sci Rep, 2018-11-07;8(1):16457.
    Species: Rat
    Sample Types: Tissue Homogenates
  108. Trans-repression of NF?B pathway mediated by PPAR? improves vascular endothelium insulin resistance
    Authors: Y Kong, Y Gao, D Lan, Y Zhang, R Zhan, M Liu, Z Zhu, G Zeng, Q Huang
    J. Cell. Mol. Med., 2018-11-05;0(0):.
    Species: Rat
    Sample Types: Serum
  109. MiR-10 targets NgR to modulate the proliferation of microglial cells and the secretion of inflammatory cytokines
    Authors: W Wang, R Zhan, J Zhou, J Wang, S Chen
    Exp. Mol. Pathol., 2018-10-09;0(0):.
    Species: Rat
    Sample Types: Cell Culture Supernates
  110. Complement depletion with cobra venom factor alleviates acute hepatic injury induced by ischemia?reperfusion
    Authors: B Wang, H Xu, J Li, HM Gao, YH Xing, Z Lin, HJ Li, YQ Wang, SH Cao
    Mol Med Rep, 2018-09-14;0(0):.
    Species: Rat
    Sample Types: Serum
  111. Lipoic Acid Prevents High-Fat Diet-Induced Hepatic Steatosis in Goto Kakizaki Rats by Reducing Oxidative Stress Through Nrf2 Activation
    Authors: CM Sena, MA Cipriano, MF Botelho, RM Seiça
    Int J Mol Sci, 2018-09-11;19(9):.
    Species: Rat
    Sample Types: Tissue Homogenates
  112. Effect of Xuefu Zhuyu Decoction Pretreatment on Myocardium in Sepsis Rats
    Authors: F Meng, H Lai, Z Luo, Y Liu, X Huang, J Chen, B Liu, Y Guo, Y Cai, Q Huang
    Evid Based Complement Alternat Med, 2018-09-09;2018(0):2939307.
    Species: Rat
    Sample Types: Serum
  113. Dysregulation of PI3K-Akt-mTOR pathway in brain of streptozotocin-induced type 2 diabetes mellitus in Wistar rats
    Authors: S Bathina, UN Das
    Lipids Health Dis, 2018-07-24;17(1):168.
    Species: Rat
    Sample Types: Plasma
  114. Cobra Venom Factor-induced complement depletion protects against lung ischemia reperfusion injury through alleviating blood-air barrier damage
    Authors: C Haihua, W Wei, H Kun, L Yuanli, L Fei
    Sci Rep, 2018-07-09;8(1):10346.
    Species: Rat
    Sample Types: BALF
  115. Anti-inflammatory effect of Mongolian drug Naru-3 on traumatic spinal cord injury and its mechanism of action
    Authors: B Baiyila, B He, G He, T Long
    J. Int. Med. Res., 2018-04-03;0(0):3000605187601.
    Species: Rat
    Sample Types: Serum
  116. Role of dysfunctional adipocytes in cholesterol-induced nonobese metabolic syndrome
    Authors: JP Huang, SC Hsu, YJ Meir, PS Hsieh, CC Chang, KH Chen, JK Chen, LM Hung
    J. Mol. Endocrinol., 2018-03-26;0(0):.
    Species: Rat
    Sample Types: Plasma
  117. The local cytokine and growth factor response to rhBMP-2 after spinal fusion
    Authors: JD Koerner, DZ Markova, GD Schroeder, BP Calio, A Shah, CW Brooks, AR Vaccaro, DG Anderson, CK Kepler
    Spine J, 2018-03-14;0(0):.
    Species: Rat
    Sample Types: Tissue Lysates
    Applications: ELISA (Standard)
  118. In Vitro and In Vivo Short-Term Pulmonary Toxicity of Differently Sized Colloidal Amorphous SiO?
    Authors: M Wiemann, UG Sauer, A Vennemann, S Bäcker, JG Keller, L Ma-Hock, W Wohlleben, R Landsiedel
    Nanomaterials (Basel), 2018-03-13;8(3):.
    Species: Rat
    Sample Types: Cell Culture Supernates
  119. Toll-like receptor 3 activation impairs excitability and synaptic activity via TRIF signalling in immature rat and human neurons
    Authors: L Ritchie, R Tate, LH Chamberlai, G Robertson, M Zagnoni, T Sposito, S Wray, JA Wright, CE Bryant, NJ Gay, TJ Bushell
    Neuropharmacology, 2018-03-02;135(0):1-10.
    Species: Rat
    Sample Types: Cell Culture Supernates
  120. Interleukin-10 attenuates impairment of the blood-brain barrier in a severe acute pancreatitis rat model
    Authors: R Lin, F Chen, S Wen, T Teng, Y Pan, H Huang
    J Inflamm (Lond), 2018-02-27;15(0):4.
    Species: Rat
    Sample Types: Serum
    Applications: ELISA (detection)
  121. The PI3K/Akt/FOXO3a pathway regulates regeneration following spinal cord injury in adult rats through TNF-? and p27kip1 expression
    Authors: H Lu, LH Zhang, L Yang, PF Tang
    Int. J. Mol. Med., 2018-02-06;0(0):.
    Species: Rat
    Sample Types: Cell Culture Supernates
  122. Ablation of the Right Cardiac Vagus Nerve Reduces Acetylcholine Content without Changing the Inflammatory Response during Endotoxemia
    Authors: K Plaschke, TQM Do, F Uhle, T Brenner, MA Weigand, J Kopitz
    Int J Mol Sci, 2018-02-01;19(2):.
    Species: Rat
    Sample Types: Plasma
  123. Short-term inhalation study of graphene oxide nanoplates
    Authors: YH Kim, MS Jo, JK Kim, JH Shin, JE Baek, HS Park, HJ An, JS Lee, BW Kim, HP Kim, KH Ahn, K Jeon, SM Oh, JH Lee, T Workman, EM Faustman, IJ Yu
    Nanotoxicology, 2018-02-01;0(0):1-15.
    Species: Rat
    Sample Types: Cell Culture Supernates
  124. ?-Melanocyte-Stimulating Hormone Protects Early Diabetic Retina from Blood-Retinal Barrier Breakdown and Vascular Leakage via MC4R
    Authors: S Cai, Q Yang, M Hou, Q Han, H Zhang, J Wang, C Qi, Q Bo, Y Ru, W Yang, Z Gu, R Wei, Y Cao, X Li, Y Zhang
    Cell. Physiol. Biochem., 2018-01-25;45(2):505-522.
    Species: Rat
    Sample Types: Tissue Homogenates
  125. Green tea extract attenuates LPS-induced retinal inflammation in rats
    Authors: JL Ren, QX Yu, WC Liang, PY Leung, TK Ng, WK Chu, CP Pang, SO Chan
    Sci Rep, 2018-01-11;8(1):429.
    Species: Rat
    Sample Types: Vitreous Humor
  126. Amelioration of streptozotocin-induced type 2 diabetes mellitus in Wistar rats by arachidonic acid
    Authors: NKV Gundala, VGM Naidu, UN Das
    Biochem. Biophys. Res. Commun., 2018-01-06;0(0):.
    Species: Rat
    Sample Types: Plasma
  127. A Novel Role of SIRT1/ FGF-21 in Taurine Protection Against Cafeteria Diet-Induced Steatohepatitis in Rats
    Authors: AH Abd Elwaha, BK Ramadan, MF Schaalan, AM Tolba
    Cell. Physiol. Biochem., 2017-09-22;43(2):644-659.
    Species: Rat
    Sample Types: Tissue Homogenates
  128. Protective effects of GV1001 on myocardial ischemia?reperfusion injury
    Authors: JE Chang, HJ Kim, S Jheon, C Lim
    Mol Med Rep, 2017-09-19;0(0):.
    Species: Rat
    Sample Types: Tissue Homogenates
  129. Scavenging of reactive oxygen species by astaxanthin inhibits epithelial-mesenchymal transition in high glucose-stimulated mesothelial cells
    Authors: K Hara, C Hamada, K Wakabayash, R Kanda, K Kaneko, S Horikoshi, Y Tomino, Y Suzuki
    PLoS ONE, 2017-09-19;12(9):e0184332.
    Species: Rat
    Sample Types: Cell Culture Supernates
  130. Betaine attenuates chronic alcohol?induced fatty liver by broadly regulating hepatic lipid metabolism
    Authors: W Yang, L Huang, J Gao, S Wen, Y Tai, M Chen, Z Huang, R Liu, C Tang, J Li
    Mol Med Rep, 2017-08-21;16(4):5225-5234.
    Species: Rat
    Sample Types: Tissue Homogenates
  131. Effects of TNF-? on penile structure alteration in rats with hyperprolactinemia
    Authors: ZL Wang, LY Yang, HH Chen, HH Lin, YT Tsai, WJ Huang
    PLoS ONE, 2017-08-01;12(8):e0181952.
    Species: Rat
    Sample Types: Serum
  132. Oral Administration of Red Ginseng Extract Promotes Neurorestoration after Compressive Spinal Cord Injury in Rats
    Authors: P Zhu, K Samukawa, H Fujita, H Kato, M Sakanaka
    Evid Based Complement Alternat Med, 2017-07-30;2017(0):1265464.
    Species: Rat
    Sample Types: Tissue Homogenates
  133. Mori Folium water extract alleviates articular cartilage damages and inflammatory responses in monosodium iodoacetate?induced osteoarthritis rats
    Authors: JW Jeong, HH Lee, J Kim, EO Choi, H Hwang-Bo, HJ Kim, MY Kim, KI Ahn, GY Kim, KW Lee, KY Kim, SG Kim, SH Hong, C Park, HJ Cha, YH Choi
    Mol Med Rep, 2017-07-21;0(0):.
    Species: Rat
    Sample Types: Serum
  134. Podophyllotoxin Extracted from Juniperus sabina Fruit Inhibits Rat Sperm Maturation and Fertility by Promoting Epididymal Epithelial Cell Apoptosis
    Authors: S Xie, G Li, L Qu, R Zhong, P Chen, Z Lu, J Zhou, X Guo, Z Li, A Ma, Y Qian, Y Zhu
    Evid Based Complement Alternat Med, 2017-07-04;2017(0):6958982.
    Species: Rat
    Sample Types: Cell Culture Supernates
  135. Estrogen-dependent efficacy of limb ischemic preconditioning in female rats
    Authors: L Pócs, Á Janovszky, D Garab, G Terhes, I Ocsovszki, J Kaszaki, M Boros, J Piffkó, A Szabó
    J. Orthop. Res., 2017-06-28;0(0):.
    Species: Rat
    Sample Types: Plasma
  136. Resveratrol protects against ICV collagenase-induced neurobehavioral and biochemical deficits
    Authors: N Singh, Y Bansal, R Bhandari, L Marwaha, R Singh, K Chopra, A Kuhad
    J Inflamm (Lond), 2017-06-09;14(0):14.
    Species: Rat
    Sample Types: Tissue Homogenates
  137. Pharmacologic targeting ERK1/2 attenuates the development and progression of hyperuricemic nephropathy in rats
    Authors: N Liu, L Xu, Y Shi, L Fang, H Gu, H Wang, X Ding, S Zhuang
    Oncotarget, 2017-05-16;8(20):33807-33826.
    Species: Rat
    Sample Types: Tissue Culture Supernates
  138. Activated Microglia Desialylate and Phagocytose Cells via Neuraminidase, Galectin-3, and Mer Tyrosine Kinase
    Authors: K Nomura, A Vilalta, DH Allendorf, TC Hornik, GC Brown
    J. Immunol., 2017-05-12;0(0):.
    Species: Rat
    Sample Types: Cell Culture Supernates
  139. Sodium tanshinone IIA sulfonate improves inflammation, aortic endothelial cell apoptosis, disseminated intravascular coagulation and multiple organ damage in a rat heat stroke model
    Authors: F Chen, H Li, G Zhu, X Chen, Z Tang
    Mol Med Rep, 2017-05-11;0(0):.
    Species: Rat
    Sample Types: Serum
  140. The Effects of Remifentanil on Expression of High Mobility Group Box 1 in Septic Rats
    Authors: KH Seo, JW Choi, HS Jung, H Yoo, JD Joo
    J. Korean Med. Sci, 2017-03-01;32(3):542-551.
    Species: Rat
    Sample Types: Serum
  141. Investigation of the effect of phlomisoside F on complete Freund's adjuvant-induced arthritis
    Authors: X Zhang, Y Dong, H Dong, W Zhang, F Li
    Exp Ther Med, 2016-12-22;13(2):710-716.
    Species: Rat
    Sample Types: Serum
  142. Postconditioning: Toll-erating mesenteric ischemia-reperfusion injury?
    Authors: Attila Szijártó
    Surgery, 2016-11-11;0(0):.
    Species: Rat
    Sample Types: Serum
  143. Transport patterns of anti-TNF-? in burn wounds: Therapeutic implications of hyaluronic acid conjugation
    Authors: Newell R Washburn
    Biomaterials, 2016-11-04;114(0):10-22.
    Species: Rat
    Sample Types: Complex Sample Type
  144. The analgesic effect of rolipram is associated with the inhibition of the activation of the spinal astrocytic JNK/CCL2 pathway in bone cancer pain
    Authors: Chi-Hua Guo
    Int. J. Mol. Med, 2016-09-30;38(5):1433-1442.
    Species: Rat
    Sample Types: Tissue Homogenates
  145. Chronic Cognitive Dysfunction after Traumatic Brain Injury Is Improved with a Phosphodiesterase 4B Inhibitor
    J Neurosci, 2016-07-06;36(27):7095-108.
    Species: Rat
    Sample Types: Tissue Homogenates
  146. Co-Administration of Cholesterol-Lowering Probiotics and Anthraquinone from Cassia obtusifolia L. Ameliorate Non-Alcoholic Fatty Liver.
    Authors: Mei L, Tang Y, Li M, Yang P, Liu Z, Yuan J, Zheng P
    PLoS ONE, 2015-09-16;10(9):e0138078.
    Species: Rat
    Sample Types: Serum
  147. IL-17A is implicated in lipopolysaccharide-induced neuroinflammation and cognitive impairment in aged rats via microglial activation.
    Authors: Sun J, Zhang S, Zhang X, Zhang X, Dong H, Qian Y
    J Neuroinflammation, 2015-09-15;12(0):165.
    Species: Rat
    Sample Types: Serum
  148. The extent of irradiation-induced long-term visceral organ damage depends on cranial/brain exposure.
    Authors: Boittin F, Denis J, Mayol J, Martigne P, Raffin F, Coulon D, Grenier N, Drouet M, Herodin F
    PLoS ONE, 2015-04-02;10(4):e0122900.
    Species: Rat
    Sample Types: Plasma
  149. Inhibition of the spinal astrocytic JNK/MCP-1 pathway activation correlates with the analgesic effects of tanshinone IIA sulfonate in neuropathic pain.
    Authors: Tang J, Zhu C, Li Z, Liu X, Sun S, Zhang T, Luo Z, Zhang H, Li W
    J Neuroinflammation, 2015-03-25;12(0):57.
    Species: Rat
    Sample Types: Tissue Homogenates
  150. Non-invasive technology that improves cardiac function after experimental myocardial infarction: Whole Body Periodic Acceleration (pGz).
    Authors: Uryash A, Bassuk J, Kurlansky P, Altamirano F, Lopez J, Adams J
    PLoS ONE, 2015-03-25;10(3):e0121069.
    Species: Rat
    Sample Types: Tissue Homogenates
  151. Xanthine oxidase inhibition alleviates the cardiac complications of insulin resistance: effect on low grade inflammation and the angiotensin system.
    Authors: El-Bassossy H, Watson M
    J Transl Med, 2015-03-06;13(0):82.
    Species: Rat
    Sample Types: Serum
  152. Ameliorative effect of allopurinol on vascular complications of insulin resistance.
    Authors: El-Bassossy H, Elberry A, Azhar A, Ghareib S, Alahdal A
    J Diabetes Res, 2015-02-15;2015(0):178540.
    Species: Rat
    Sample Types: Serum
  153. Melatonin attenuates the TLR4-mediated inflammatory response through MyD88- and TRIF-dependent signaling pathways in an in vivo model of ovarian cancer.
    Authors: Chuffa L, Fioruci-Fontanelli B, Mendes L, Ferreira Seiva F, Martinez M, Favaro W, Domeniconi R, Pinheiro P, Delazari Dos Santos L, Martinez F
    BMC Cancer, 2015-02-06;15(0):34.
    Species: Rat
    Sample Types: Tissue Culture Supernates
  154. Preventive effects of probiotic bacteria Lactobacillus plantarum and dietary fiber in chemically-induced mammary carcinogenesis.
    Authors: Kassayova M, Bobrov N, Strojny L, Kiskova T, Mikes J, Demeckova V, Orendas P, Bojkova B, Pec M, Kubatka P, Bomba A
    Anticancer Res, 2014-09-01;34(9):4969-75.
    Species: Rat
    Sample Types: Serum
  155. Prolonged neuroinflammation after lipopolysaccharide exposure in aged rats.
    Authors: Fu H, Yang T, Xiao W, Fan L, Wu Y, Terrando N, Wang T
    PLoS ONE, 2014-08-29;9(8):e106331.
    Species: Rat
    Sample Types: Serum
  156. Melatonin synergized with cyclosporine A improves cardiac allograft survival by suppressing inflammation and apoptosis.
    Authors: Liu C, Hong T, Shao M, Chen Z, Wang C
    Mol Med Rep, 2014-07-15;10(3):1323-8.
    Species: Rat
    Sample Types: Serum
  157. Improving membrane based multiplex immunoassays for semi-quantitative detection of multiple cytokines in a single sample.
    Authors: Altara, Raffaele, Manca, Marco, Hessel, Marleen, Janssen, Ben J, Struijker-Boudier, Harry H, Hermans, Rob J J, Blankesteijn, W Matthi
    BMC Biotechnol, 2014-07-15;14(0):63.
    Species: Rat
    Sample Types: Serum
  158. Catalpol ameliorates sodium taurocholate-induced acute pancreatitis in rats via inhibiting activation of nuclear factor kappa B.
    Authors: Xiao W, Yin G, Fan Y, Qiu L, Cang X, Yu G, Hu Y, Xing M, Wu D, Wang X, Hu G, Wan R
    Int J Mol Sci, 2014-07-04;15(7):11957-72.
    Species: Rat
    Sample Types: Serum
  159. Dose responsive effects of subcutaneous pentosan polysulfate injection in mucopolysaccharidosis type VI rats and comparison to oral treatment.
    Authors: Frohbergh M, Ge Y, Meng F, Karabul N, Solyom A, Lai A, Iatridis J, Schuchman E, Simonaro C
    PLoS ONE, 2014-06-25;9(6):e100882.
    Species: Rat
    Sample Types: Serum
  160. Pentoxifylline alleviates cardiac ischemia and dysfunction following experimental angina in insulin resistance.
    Authors: Azhar A, El-Bassossy H
    PLoS ONE, 2014-05-29;9(5):e98281.
    Species: Rat
    Sample Types: Serum
  161. Epidermal growth factor receptor inhibitor ameliorates excessive astrogliosis and improves the regeneration microenvironment and functional recovery in adult rats following spinal cord injury.
    Authors: Li Z, Li J, Wang L, Zhang J, Wu J, Mao X, Shi G, Wang Q, Wang F, Zou J
    J Neuroinflammation, 2014-04-05;11(0):71.
    Species: Rat
    Sample Types: Cell Culture Supernates
  162. Deoxyglucose prevents neurodegeneration in culture by eliminating microglia.
    Authors: Vilalta, Anna, Brown, Guy C
    J Neuroinflammation, 2014-03-26;11(0):58.
    Species: Rat
    Sample Types: Cell Culture Supernates
  163. Rhamnogalacturonan from Acmella oleracea (L.) R.K. Jansen: gastroprotective and ulcer healing properties in rats.
    Authors: Maria-Ferreira D, da Silva L, Mendes D, Cabrini D, Nascimento A, Iacomini M, Cipriani T, Santos A, Werner M, Baggio C
    PLoS ONE, 2014-01-08;9(1):e84762.
    Species: Rat
    Sample Types: Tissue Culture Supernates
  164. Cerebral ischemia is exacerbated by extracellular nicotinamide phosphoribosyltransferase via a non-enzymatic mechanism.
    Authors: Zhao B, Zhang M, Han X, Zhang X, Xing Q, Dong X, Shi Q, Huang P, Lu Y, Wei E, Xia Q, Zhang W, Tang C
    PLoS ONE, 2013-12-31;8(12):e85403.
    Species: Rat
    Sample Types: Cell Culture Supernates
  165. Ubiquitin-specific peptidase 5, a target molecule of vialinin A, is a key molecule of TNF-alpha production in RBL-2H3 cells.
    Authors: Yoshioka Y, Ye Y, Okada K, Taniguchi K, Yoshida A, Sugaya K, Onose J, Koshino H, Takahashi S, Yajima A, Yajima S, Abe N
    PLoS ONE, 2013-12-04;8(12):e80931.
    Species: Rat
    Sample Types: Whole Cells
  166. Mechanical ventilation enhances HMGB1 expression in an LPS-induced lung injury model.
    Authors: Ding N, Wang F, Xiao H, Xu L, She S
    PLoS ONE, 2013-09-10;8(9):e74633.
    Species: Rat
    Sample Types: BALF
  167. Suppression of neuroinflammatory and apoptotic signaling cascade by curcumin alone and in combination with piperine in rat model of olfactory bulbectomy induced depression.
    Authors: Rinwa P, Kumar A, Garg S
    PLoS ONE, 2013-04-17;8(4):e61052.
    Species: Rat
    Sample Types: Tissue Homogenates
  168. Medium-chain fatty acid-sensing receptor, GPR84, is a proinflammatory receptor.
    Authors: Suzuki M, Takaishi S, Nagasaki M, Onozawa Y, Iino I, Maeda H, Komai T, Oda T
    J Biol Chem, 2013-02-28;288(15):10684-91.
    Species: Rat
    Sample Types: Serum
  169. Caspase inhibitors protect neurons by enabling selective necroptosis of inflamed microglia.
    Authors: Fricker M, Vilalta A, Tolkovsky A, Brown G
    J Biol Chem, 2013-02-05;288(13):9145-52.
    Species: Rat
    Sample Types: Cell Culture Supernates
  170. Positional isomers of aspirin are equally potent in inhibiting colon cancer cell growth: differences in mode of cyclooxygenase inhibition.
    Authors: Kodela R, Chattopadhyay M, Goswami S, Gan Z, Rao P, Nia K, Velazquez-Martinez C, Kashfi K
    J Pharmacol Exp Ther, 2013-01-24;345(1):85-94.
    Species: Rat
    Sample Types: Plasma
  171. A short course of infusion of a hydrogen sulfide-donor attenuates endotoxemia induced organ injury via stimulation of anti-inflammatory pathways, with no additional protection from prolonged infusion.
    Cytokine, 2012-12-23;61(2):614-21.
    Species: Rat
    Sample Types: BALF
  172. Keratinocyte expression of inflammatory mediators plays a crucial role in substance P-induced acute and chronic pain.
    J Neuroinflammation, 2012-07-23;9(0):181.
    Species: Rat
    Sample Types: Tissue Homogenates
  173. Glial tumor necrosis factor alpha (TNF-alpha) generates metaplastic inhibition of spinal learning.
    Authors: Huie JR, Baumbauer KM, Lee KH, Bresnahan JC, Beattie MS, Ferguson AR, Grau JW
    PLoS ONE, 2012-06-20;7(6):e39751.
    Species: Rat
    Sample Types: Tissue Homogenates
  174. The effects of low-dose ionizing radiation in the activated rat basophilic leukemia (RBL-2H3) mast cells.
    Authors: Joo H, Nam S, Yang K, Kim C, Jin Y, Kim J
    J Biol Chem, 2012-06-14;287(33):27789-95.
    Species: Rat
    Sample Types: Cell Culture Supernates
  175. Anti-inflammatory effects of FTY720 do not prevent neuronal cell loss in a rat model of optic neuritis.
    Authors: Rau CR, Hein K, Sattler MB, Kretzschmar B, Hillgruber C, McRae BL, Diem R, Bahr M
    Am. J. Pathol., 2011-02-26;178(4):1770-81.
    Species: Rat
    Sample Types: Tissue Homogenates
  176. Systemic effects of ulna loading in male rats during functional adaptation.
    Authors: Sample SJ, Collins RJ, Wilson AP, Racette MA, Behan M, Markel MD, Kalscheur VL, Hao Z, Muir P
    J. Bone Miner. Res., 2010-09-01;25(9):2016-28.
    Species: Rat
    Sample Types: Plasma
  177. Vipera aspis venom reduces lethality and down-regulates tumor necrosis factor-alpha in a rat model of LPS-induced sepsis.
    Authors: Frolkis I, Klein Y, Locker C, Adi N, Dahan E, Uretzsky G, Shapira I, Sorkine P
    Cytokine, 2010-01-19;49(3):319-24.
    Species: Rat
    Sample Types: Serum
  178. Protease-activated receptor 2 blocking peptide counteracts endotoxin-induced inflammation and coagulation and ameliorates renal fibrin deposition in a rat model of acute renal failure.
    Authors: Jesmin S, Gando S, Zaedi S, Prodhan SH, Sawamura A, Miyauchi T, Hiroe M, Yamaguchi N
    Shock, 2009-12-01;32(6):626-32.
    Species: Rat
    Sample Types: Plasma
  179. Tumor necrosis factor-alpha participates in apoptosis in the limbic system after myocardial infarction.
    Authors: Kaloustian S, Bah TM, Rondeau I, Mathieu S, Lada-Moldovan L, Ryvlin P, Godbout R, Rousseau G
    Apoptosis, 2009-11-01;0(0):.
    Species: Rat
    Sample Types: Plasma
  180. House dust mite induces direct airway inflammation in vivo: implications for future disease therapy?
    Authors: De Alba J, Raemdonck K, Dekkak A, Collins M, Wong S, Nials AT, Knowles RG, Belvisi MG, Birrell MA
    Eur. Respir. J., 2009-10-19;35(6):1377-87.
    Species: Rat
    Sample Types: BALF
  181. Hypercapnic acidosis attenuates shock and lung injury in early and prolonged systemic sepsis.
    Authors: Costello J, Higgins B, Contreras M, Chonghaile MN, Hassett P, O'Toole D, Laffey JG
    Crit. Care Med., 2009-08-01;37(8):2412-20.
    Species: Rat
    Sample Types: BALF
  182. Effects of an antagonist of the gastrin-releasing peptide receptor in an animal model of uveitis.
    Authors: Pereira DV, Steckert AV, Mina F, Petronilho F, Roesler R, Schwartsmann G, Ritter C, Dal-Pizzol F
    Invest. Ophthalmol. Vis. Sci., 2009-06-10;50(11):5300-3.
    Species: Rat
    Sample Types: Aqueous Humor
  183. In vivo Angiotensin II AT1 receptor blockade selectively inhibits LPS-induced innate immune response and ACTH release in rat pituitary gland.
    Authors: Sanchez-Lemus E, Benicky J, Pavel J, Saavedra JM
    Brain Behav. Immun., 2009-05-07;23(7):945-57.
    Species: Rat
    Sample Types: Plasma
  184. Role of sensory innervation in the rat pulmonary neutrophil recruitment induced by staphylococcal enterotoxins type A and B.
    Authors: Desouza IA, Camargo EA, Mariano NS, Optiz-Neto JB, Resende JS, Mello GC, Costa SK, De Nucci G, Antunes E
    Eur. J. Pharmacol., 2009-04-16;613(1):128-34.
    Species: Rat
    Sample Types: Cell Culture Supernates
  185. Mechanism of hepatoprotection in proestrus female rats following trauma-hemorrhage: heme oxygenase-1-derived normalization of hepatic inflammatory responses.
    Authors: Yang S, Hu S, Chen J, Choudhry MA, Rue LW, Bland KI, Chaudry IH
    J. Leukoc. Biol., 2009-02-24;85(6):1015-26.
    Species: Rat
    Sample Types: Serum
  186. 4-thiouridine induces dose-dependent reduction of oedema, leucocyte influx and tumour necrosis factor in lung inflammation.
    Authors: Evaldsson C, Ryden I, Rosen A, Uppugunduri S
    Clin. Exp. Immunol., 2008-12-01;155(2):330-8.
    Species: Rat
    Sample Types: BALF
  187. Effects of the immunomodulator, VGX-1027, in endotoxin-induced uveitis in Lewis rats.
    Authors: Mangano K, Sardesai NY, Quattrocchi C, Mazzon E, Cuzzocrea S, Bendtzen K, Meroni PL, Kim JJ, Nicoletti F
    Br. J. Pharmacol., 2008-09-08;155(5):722-30.
    Species: Rat
    Sample Types: Aqueous Humor
  188. Role of central beta-adrenergic receptors in regulating proinflammatory cytokine responses to a peripheral bacterial challenge.
    Authors: Johnson JD, Cortez V, Kennedy SL, Foley TE, Hanson H, Fleshner M
    Brain Behav. Immun., 2008-05-12;22(7):1078-86.
    Species: Rat
    Sample Types: Plasma
  189. Substance P acts via the neurokinin receptor 1 to elicit bronchoconstriction, oxidative stress, and upregulated ICAM-1 expression after oil smoke exposure.
    Authors: Li PC, Chen WC, Chang LC, Lin SC
    Am. J. Physiol. Lung Cell Mol. Physiol., 2008-03-07;294(5):L912-20.
    Species: Rat
    Sample Types: BALF
  190. Antithrombin inhibits bronchoalveolar activation of coagulation and limits lung injury during Streptococcus pneumoniae pneumonia in rats.
    Authors: Choi G, Hofstra JJ, Roelofs JJ, Rijneveld AW, Bresser P, van der Zee JS, Florquin S, van der Poll T, Levi M, Schultz MJ
    Crit. Care Med., 2008-01-01;36(1):204-10.
    Species: Rat
    Sample Types: BALF
  191. Role of sex steroids in modulating tumor necrosis factor alpha-induced changes in vascular function and blood pressure.
    Authors: LaMarca BD, Chandler DL, Grubbs L, Bain J, McLemore GR, Granger JP, Ryan MJ
    Am. J. Hypertens., 2007-11-01;20(11):1216-21.
    Species: Rat
    Sample Types: Serum
  192. Triamcinolone acetonide protects the rat retina from STZ-induced acute inflammation and early vascular leakage.
    Authors: Kim YH, Choi MY, Kim YS, Park CH, Lee JH, Chung IY, Yoo JM, Choi WS, Cho GJ, Kang SS
    Life Sci., 2007-08-31;81(14):1167-73.
    Species: Rat
    Sample Types: Tissue Homogenates
  193. Comprehensive gene expression profiling of rat lung reveals distinct acute and chronic responses to cigarette smoke inhalation.
    Authors: Stevenson CS, Docx C, Webster R, Battram C, Hynx D, Giddings J, Cooper PR, Chakravarty P, Rahman I, Marwick JA, Kirkham PA, Charman C, Richardson DL, Nirmala NR, Whittaker P, Butler K
    Am. J. Physiol. Lung Cell Mol. Physiol., 2007-08-24;293(5):L1183-93.
    Species: Rat
    Sample Types: BALF
  194. In the adult mesenchymal stem cell population, source gender is a biologically relevant aspect of protective power.
    Authors: Crisostomo PR, Markel TA, Wang M, Lahm T, Lillemoe KD, Meldrum DR
    Surgery, 2007-08-01;142(2):215-21.
    Species: Rat
    Sample Types: Cell Culture Supernates
  195. Expression of the mu opioid receptor in the human immunodeficiency virus type 1 transgenic rat model.
    Authors: Chang SL, Beltran JA, Swarup S
    J. Virol., 2007-06-06;81(16):8406-11.
    Species: Rat
    Sample Types: Serum
  196. Natural anticoagulants limit lipopolysaccharide-induced pulmonary coagulation but not inflammation.
    Authors: Choi G, Vlaar AP, Schouten M, Van't Veer C, van der Poll T, Levi M, Schultz MJ
    Eur. Respir. J., 2007-05-30;30(3):423-8.
    Species: Rat
    Sample Types: Tissue Homogenates
  197. 5-aminosalicylic acid improves indomethacin-induced enteropathy by inhibiting iNOS transcription in rats.
    Authors: Nandi J, Saud B, Zinkievich JM, Palma DT, Levine RA
    Dig. Dis. Sci., 2007-05-15;53(1):123-32.
    Species: Rat
    Sample Types: Serum
  198. Changes of gene expression of iron regulatory proteins during turpentine oil-induced acute-phase response in the rat.
    Authors: Sheikh N, Dudas J, Ramadori G
    Lab. Invest., 2007-04-09;87(7):713-25.
    Species: Rat
    Sample Types: Serum
  199. Prothymosin alpha lacking the nuclear localization signal as an effective gene therapeutic strategy in collagen-induced arthritis.
    Authors: Shiau AL, Chen SY, Chang MY
    J. Immunol., 2007-04-01;178(7):4688-94.
    Species: Rat
    Sample Types: Tissue Homogenates
  200. Cell-based angiopoietin-1 gene therapy for acute lung injury.
    Authors: McCarter SD, Mei SH, Lai PF, Zhang QW, Parker CH, Suen RS, Hood RD, Zhao YD, Deng Y, Han RN, Dumont DJ, Stewart DJ
    Am. J. Respir. Crit. Care Med., 2007-02-22;175(10):1014-26.
    Species: Rat
    Sample Types: BALF
  201. The arthritis severity quantitative trait loci Cia4 and Cia6 regulate neutrophil migration into inflammatory sites and levels of TNF-alpha and nitric oxide.
    Authors: Laragione T, Yarlett NC, Brenner M, Mello A, Sherry B, Miller EJ, Metz CN, Gulko PS
    J. Immunol., 2007-02-15;178(4):2344-51.
    Species: Rat
    Sample Types: Air Pouch Exudate
  202. Interleukin-6 mediates low-threshold mechanical allodynia induced by intrathecal HIV-1 envelope glycoprotein gp120.
    Authors: Schoeniger-Skinner DK, Ledeboer A, Frank MG, Milligan ED, Poole S, Martin D, Maier SF, Watkins LR
    Brain Behav. Immun., 2007-01-03;21(5):660-7.
    Species: Rat
    Sample Types: CSF
  203. Bacterial translocation is downregulated by anti-TNF-alpha monoclonal antibody administration in rats with cirrhosis and ascites.
    Authors: Frances R, Chiva M, Sanchez E, Gonzalez-Navajas JM, Llovet T, Zapater P, Soriano G, Munoz C, Balanzo J, Perez-Mateo M, Song XY, Guarner C, Such J
    J. Hepatol., 2006-12-27;46(5):797-803.
    Species: Rat
    Sample Types: Serum
  204. Anti-rat soluble IL-6 receptor antibody down-regulates cardiac IL-6 and improves cardiac function following trauma-hemorrhage.
    Authors: Yang S, Hu S, Choudhry MA, Rue LW, Bland KI, Chaudry IH
    J. Mol. Cell. Cardiol., 2006-12-16;42(3):620-30.
    Species: Rat
    Sample Types: Plasma
  205. Anti-inflammatory effects of inhaled nitric oxide are optimized at lower oxygen concentration in experimental Klebsiella pneumoniae pneumonia.
    Authors: Sun Z, Sun B, Wang X, Wang W, Zhu L
    Inflamm. Res., 2006-10-01;55(10):430-40.
    Species: Rat
    Sample Types: Tissue Homogenates
  206. P2Y1 receptor-evoked glutamate exocytosis from astrocytes: control by tumor necrosis factor-alpha and prostaglandins.
    Authors: Domercq M, Brambilla L, Pilati E, Marchaland J, Volterra A, Bezzi P
    J. Biol. Chem., 2006-08-01;281(41):30684-96.
    Species: Rat
    Sample Types: Cell Culture Supernates
  207. Doxycycline reduces mortality and injury to the brain and cochlea in experimental pneumococcal meningitis.
    Authors: Meli DN, Coimbra RS, Erhart DG, Loquet G, Bellac CL, Tauber MG, Neumann U, Leib SL
    Infect. Immun., 2006-07-01;74(7):3890-6.
    Species: Rat
    Sample Types: CSF
  208. Biomarker and drug-target discovery using proteomics in a new rat model of sepsis-induced acute renal failure.
    Authors: Holly MK, Dear JW, Hu X, Schechter AN, Gladwin MT, Hewitt SM, Yuen PS, Star RA
    Kidney Int., 2006-06-07;70(3):496-506.
    Species: Rat
    Sample Types: Serum
  209. Glucosamine administration during resuscitation improves organ function after trauma hemorrhage.
    Authors: Yang S, Zou LY, Bounelis P, Chaudry I, Chatham JC, Marchase RB
    Shock, 2006-06-01;25(6):600-7.
    Species: Rat
    Sample Types: Serum
  210. Resuscitation from experimental heatstroke by estrogen therapy.
    Authors: Chen SH, Chang FM, Niu KC, Lin MY, Lin MT
    Crit. Care Med., 2006-04-01;34(4):1113-8.
    Species: Rat
    Sample Types: Serum
  211. Effects of gabexate mesilate on serum inflammatory cytokines in rats with acute necrotizing pancreatitis.
    Authors: Chen CC, Wang SS, Tsay SH, Lee FY, Lu RH, Chang FY, Lee SD
    Cytokine, 2006-02-10;33(2):95-9.
    Species: Rat
    Sample Types: Serum
  212. Interleukin-10 aerosol reduces proinflammatory mediators in bronchoalveolar fluid of endotoxemic rat.
    Authors: Hofstetter C, Flondor M, Hoegl S, Muhl H, Zwissler B
    Crit. Care Med., 2005-10-01;33(10):2317-22.
    Species: Rat
    Sample Types: BALF, Plasma
  213. Prophylactic adenovirus-mediated human kallistatin gene therapy suppresses rat arthritis by inhibiting angiogenesis and inflammation.
    Authors: Wang CR, Chen SY, Wu CL, Liu MF, Jin YT, Chao L, Chao J
    Arthritis Rheum., 2005-04-01;52(4):1319-24.
    Species: Rat
    Sample Types: Tissue Homogenates
  214. Developmental changes induced by graded prenatal systemic hypoxic-ischemic insults in rats.
    Authors: Robinson S, Petelenz K, Li Q, Cohen ML, Dechant A, Tabrizi N, Bucek M, Lust D, Miller RH
    Neurobiol. Dis., 2005-04-01;18(3):568-81.
    Species: Rat
    Sample Types: Tissue Homogenates
  215. Effects of pyrrolidine dithiocarbamate, an NF-kappaB inhibitor, on cytokine expression and ocular inflammation in experimental autoimmune anterior uveitis.
    Authors: Fang IM, Yang CH, Lin CP, Yang CM, Chen MS
    J Ocul Pharmacol Ther, 2005-04-01;21(2):95-106.
    Species: Rat
    Sample Types: Aqueous Humor
  216. Suppression of autoimmune retinal disease by lovastatin does not require Th2 cytokine induction.
    Authors: Gegg ME, Harry R, Hankey D, Zambarakji H, Pryce G, Baker D, Adamson P, Calder V, Greenwood J
    J. Immunol., 2005-02-15;174(4):2327-35.
    Species: Rat
    Sample Types: Cell Culture Supernates
  217. Tumor necrosis factor alpha expression and protein levels after fluid percussion injury in rats: the effect of injury severity and brain temperature.
    Authors: Vitarbo EA, Chatzipanteli K, Kinoshita K, Truettner JS, Alonso OF, Dietrich WD
    Neurosurgery, 2004-08-01;55(2):416-24; discu.
    Species: Rat
    Sample Types: Serum
  218. Anti-inflammatory effects of alpha-melanocyte-stimulating hormone against rat endotoxin-induced uveitis and the time course of inflammatory agents in aqueous humor.
    Authors: Nishida T, Miyata S, Itoh Y, Mizuki N, Ohgami K, Shiratori K, Ilieva IB, Ohno S, Taylor AW
    Int. Immunopharmacol., 2004-08-01;4(8):1059-66.
    Species: Rat
    Sample Types: Aqueous Humor
  219. HIV-1 gp120 stimulates proinflammatory cytokine-mediated pain facilitation via activation of nitric oxide synthase-I (nNOS).
    Authors: Holguin A, O&amp;apos;Connor KA, Biedenkapp J, Campisi J, Wieseler-Frank J, Milligan ED, Hansen MK, Spataro L, Maksimova E, Bravmann C, Martin D, Fleshner M, Maier SF, Watkins LR
    Pain, 2004-08-01;110(3):517-30.
    Species: Rat
    Sample Types: CSF
  220. Insulin treatment improves hepatic morphology and function through modulation of hepatic signals after severe trauma.
    Authors: Schubert T, Horch RE
    Ann. Surg., 2004-08-01;240(2):340-9.
    Species: Rat
    Sample Types: Tissue Homogenates
  221. Ameliorating effects of the immunomodulator 3-(2-ethylphenyl)-5-(3-methoxyphenyl)-1H-1,2,4-triazole in an experimental model of colitis in the rat.
    Authors: Stasi MA, Ruggiero V, Ursillo A, Taurelli R, Agliano M, Weber E, Lorenzoni P, Sorrentino V, Pacifici L, Carminati P
    Eur. J. Pharmacol., 2004-06-28;494(2):263-72.
    Species: Rat
    Sample Types: Tissue Homogenates
  222. Insulin attenuates the systemic inflammatory response in endotoxemic rats.
    Authors: Jeschke MG, Klein D, Bolder U, Einspanier R
    Endocrinology, 2004-06-10;145(9):4084-93.
    Species: Rat
    Sample Types: Tissue Homogenates
  223. Gene transfer of tumor necrosis factor inhibitor improves the function of lung allografts.
    Authors: Tagawa T, Kozower BD, Kanaan SA, Daddi N, Muraoka M, Oka T, Ritter JH, Patterson GA
    J. Thorac. Cardiovasc. Surg., 2004-06-01;127(6):1558-63.
    Species: Rat
    Sample Types: Tissue Homogenates
  224. A method for measuring multiple cytokines from small samples.
    Authors: O&amp;apos;Connor KA
    Brain Behav. Immun., 2004-05-01;18(3):274-80.
    Species: Rat
    Sample Types: CSF
  225. Oral (gavage), in utero and post-natal exposure of Sprague-Dawley rats to low doses of tributyltin chloride. Part II: effects on the immune system.
    Authors: Tryphonas H, Cooke G, Caldwell D, Bondy G, Parenteau M, Hayward S, Pulido O
    Food Chem. Toxicol., 2004-02-01;42(2):221-35.
    Species: Rat
    Sample Types: Serum
  226. Alveolar macrophage cytotoxicity for normal lung fibroblasts is mediated by nitric oxide release.
    Authors: Morgan DL, Shines CJ
    Toxicol In Vitro, 2004-02-01;18(1):139-46.
    Species: Rat
    Sample Types: Cell Culture Supernates
  227. Differential cytokine response in interstitial fluid in skin and serum during experimental inflammation in rats.
    Authors: Nedrebo T, Reed RK, Jonsson R, Berg A, Wiig H
    J. Physiol. (Lond.), 2004-01-14;556(0):193-202.
    Species: Rat
    Sample Types: Interstitial Fluid
  228. Differential expression of cytokine genes and inducible nitric oxide synthase induced by opacity phenotype variants of Streptococcus pneumoniae during acute otitis media in the rat.
    Authors: Long JP, Tong HH, Shannon PA, DeMaria TF
    Infect. Immun., 2003-10-01;71(10):5531-40.
    Species: Rat
    Sample Types: Tissue Secretion
  229. Iron intake increases infarct volume after permanent middle cerebral artery occlusion in rats.
    Authors: Castellanos M, Puig N, Carbonell T, Castillo J, Martinez J, Rama R, Davalos A
    Brain Res., 2002-10-11;952(1):1-6.
  230. Recipient intramuscular cotransfection of naked plasmid transforming growth factor beta1 and interleukin 10 ameliorates lung graft ischemia-reperfusion injury.
    Authors: D&amp;apos;Ovidio F
    J. Thorac. Cardiovasc. Surg., 2002-08-01;124(2):259-69.
    Species: Rat
    Sample Types: BALF
  231. Differential effects of ebselen on neutrophil recruitment, chemokine, and inflammatory mediator expression in a rat model of lipopolysaccharide-induced pulmonary inflammation.
    Authors: Haddad el-B, McCluskie K, Birrell MA, Dabrowski D, Pecoraro M, Underwood S, Chen B, De Sanctis GT, Webber SE, Foster ML, Belvisi MG
    J. Immunol., 2002-07-15;169(2):974-82.
    Species: Rat
    Sample Types: BALF
  232. Gene transfer of transforming growth factor-beta1 to the rat peritoneum: effects on membrane function.
    Authors: Margetts PJ, Kolb M, Galt T, Hoff CM, Shockley TR, Gauldie J
    J. Am. Soc. Nephrol., 2001-10-01;12(10):2029-39.
    Species: Rat
    Sample Types: Peritoneal Fluid

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Reviews for Rat TNF-alpha Quantikine ELISA Kit

Average Rating: 4.9 (Based on 12 Reviews)

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Rat TNF-alpha Quantikine ELISA Kit
By Anonymous on 09/07/2020
Sample Tested: Cell Lysates
Rat TNF-alpha Quantikine ELISA Kit RTA00
Rat TNF-alpha Quantikine ELISA Kit
By Anonymous on 03/13/2020
Sample Tested: Spinal cord tissue

We tested TNF-alpha levels in homogenized rat spinal cord. The standard curve was excellent and the CV values were all very low. We have used kits from other companies and found RnD systems kits to be superior to all other companies. The kits from RnD systems result in much lower background levels and much lower CV levels, which really helps with consistency and repeatability. The image shows the standard curve and the green outlines the low CV values from a run containing homogenized rat spinal cord.

Rat TNF-alpha Quantikine ELISA Kit
By Anonymous on 03/06/2020
Sample Tested: Cerebrospinal Fluid
Rat TNF-alpha Quantikine ELISA Kit
By Anonymous on 04/12/2018
Sample Tested: B16-F1 mouse melanoma cell line
Rat TNF-alpha Quantikine ELISA Kit
By Anonymous on 03/30/2018
Sample Tested: L6 rat myoblast cell line
Rat TNF-alpha Quantikine ELISA Kit
By Anonymous on 03/14/2018
Sample Tested: A7r5 rat thoracic aortic smooth muscle cell line
Rat TNF-alpha Quantikine ELISA Kit
By Anonymous on 03/08/2018
Sample Tested: Serum-free Cell Culture Supernates
Rat TNF-alpha Quantikine ELISA Kit
By Shub Poddar on 03/07/2018
Sample Tested: C6 rat glioma cell line
Rat TNF-alpha Quantikine ELISA Kit
By Anonymous on 02/17/2018
Sample Tested: 4T1.2 mouse mammary carcinoma cells
Rat TNF-alpha Quantikine ELISA Kit
By Anonymous on 02/14/2018
Sample Tested: Cell culture supernatant
Rat TNF-alpha Quantikine ELISA Kit
By Anonymous on 02/08/2018
Sample Tested: Serum
Rat TNF-alpha Quantikine ELISA Kit
By Anonymous on 10/20/2017
Sample Tested: Heparin Plasma