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Recombinant Mouse EGF Protein, CF

Catalog #: 2028-EG
158 Citations 5 Reviews Datasheet / COA / SDS
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2028-EG-200
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Recombinant Mouse EGF Protein, CF Summary

Product Specifications

Purity
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
Endotoxin Level
<0.10 EU per 1 μg of the protein by the LAL method.
Activity
Measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblast cells. Rubin, J.S. et al. (1991) Proc. Natl. Acad. Sci. USA 88:415. The ED50 for this effect is 20-100 pg/mL.
Source
E. coli-derived mouse EGF protein
Asn977-Arg1029, with an N-terminal Met
Accession #
NP_034243
N-terminal Sequence
Analysis
Met
Predicted Molecular Mass
6.2 kDa

Product Datasheets

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2028-EG

Product Datasheet
COA
SDS

Carrier Free

What does CF mean?

CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. The carrier free version does not contain BSA.

What formulation is right for me?

In general, we advise purchasing the recombinant protein with BSA for use in cell or tissue culture, or as an ELISA standard. In contrast, the carrier free protein is recommended for applications, in which the presence of BSA could interfere.

2028-EG

Formulation Lyophilized from a 0.2 μm filtered solution in Acetonitrile and TFA.
Reconstitution Reconstitute at 200 μg/mL in sterile PBS.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.
Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: EGF

Epidermal growth factor (EGF) is a small, potent growth factor capable of inducing cell proliferation, differentiation, and survival. EGF is the founding member of the EGF family that also includes TGF-alpha, amphiregulin (AR), betacellulin (BTC), epiregulin (EPR), heparin‑binding EGF‑like growth factor (HB‑EGF), epigen, and the neuregulins (NRG)-1 through -6 (1). Members of The EGF family are characterized by a shared structural motif, the EGF‑like domain, which contains three intramolecular disulfide bonds that are formed by six similarly spaced, conserved cysteine residues (2). These disulfide bonds are essential for proper protein conformation and receptor binding. All EGF family members are synthesized as type I transmembrane precursor proteins that may contain several EGF domains in the extracellular region. The mature proteins are released from the cell surface by regulated proteolysis (1). The full length EGF protein is 1207 amino acids (aa) (EGF precursor) containing nine EGF domains and nine LDLR class B repeats. However, the mature protein is much smaller, only 53 aa, and is generated by proteolytic cleavage of the EGF domain proximal to the transmembrane region (3). EGF is well conserved across mammals with mature human EGF 70% identical to mature mouse and rat EGF. Physiologically, EGF is found in various body fluids, including blood, milk, urine, saliva, seminal fluid, pancreatic juice, cerebrospinal fluid, and amniotic fluid (4). EGF is a high affinity ligand of the EGF receptor (ErbB). Four ErbB (HER) family receptor tyrosine kinases including EGFR/ErbB1, ErbB2, ErbB3 and ErbB4, mediate responses to EGF family members (5). EGF binding induces dimerization of the EGF receptor resulting in activation of the protein tyrosine kinase signaling pathway. These receptors undergo a complex pattern of ligand-induced homo- or hetero-dimerization to transduce EGF family signals (6, 7). EGF binds ErbB1 and depending on the context, induces the formation of homodimers or heterodimers containing ErbB2. Dimerization results in autophosphorylation of the receptor at specific tyrosine residues to create docking sites for a variety of signaling molecules (5, 8). Biological activities ascribed to EGF include epithelial development, angiogenesis, inhibition of gastric acid secretion, fibroblast proliferation, and colony formation of epidermal cells in culture.

References
  1. Harris, R.C. et al. (2003) Exp. Cell Res. 284:2.
  2. Carpenter, G. and Cohen, S. (1990) J. Biol. Chem. 265:7709.
  3. Gray, A. et al. (1983) Nature 303:722.
  4. Carpenter, G. and Zendegui, J.G. (1986) Exp. Cell Res. 164:1.
  5. Jorissen, R.N. et al. (2003) Exp. Cell Res. 284:31.
  6. Gamett, D.C. et al. (1997) J. Biol. Chem. 272:12052.
  7. Qian, X. et al. (1994) Proc. Natl. Acad. Sci. 91:1500.
  8. Qian, X. et al. (1999) J. Biol. Chem. 274:574.
    Long Name
    Epidermal Growth Factor
    Entrez Gene IDs
    1950 (Human); 13645 (Mouse); 25313 (Rat)
    Alternate Names
    beta-urogastrone; EGF; epidermal growth factor (beta-urogastrone); epidermal growth factor; hEGF; HOMG4; pro-epidermal growth factor; URG; Urogastrone

    Citations for Recombinant Mouse EGF Protein, CF

    R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

    158 Citations: Showing 1 - 10
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    1. Accessible luminal interface of bovine rectal organoids generated from cryopreserved biopsy tissues
      Authors: Kawasaki, M;Ambrosini, YM;
      PloS one
      Species: Bovine astrovirus
      Sample Types: Organoid
      Applications: Bioassay
    2. KR158 spheres harboring slow-cycling cells recapitulate GBM features in an immunocompetent system
      Authors: Chakraborty, A;Yang, C;Kresak, JL;Silver, A;Feier, D;Tian, G;Andrews, M;Sobanjo, OO;Hodge, ED;Engelbart, MK;Huang, J;Harrison, JK;Sarkisian, MR;Mitchell, DA;Deleyrolle, LP;
      bioRxiv : the preprint server for biology
      Species: Murine polyomavirus strain A3
      Sample Types: Whole Cells
      Applications: Bioassay
    3. Golgi organization is a determinant of stem cell function in the small intestine
      Authors: S Scharaw, A Sola-Carva, I Belevich, AT Webb, S Das, S Andersson, N Pentinmikk, EJ Villablanc, JR Goldenring, E Jokitalo, RJ Coffey, P Katajisto
      bioRxiv : the preprint server for biology, 2023-03-24;0(0):.
      Species: Mouse
      Sample Types: Organoid
      Applications: Bioassay
    4. Bile salt hydrolase in non-enterotoxigenic Bacteroides potentiates colorectal cancer
      Authors: L Sun, Y Zhang, J Cai, B Rimal, ER Rocha, JP Coleman, C Zhang, RG Nichols, Y Luo, B Kim, Y Chen, KW Krausz, CC Harris, AD Patterson, Z Zhang, S Takahashi, FJ Gonzalez
      Nature Communications, 2023-02-10;14(1):755.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    5. In situ modulation of intestinal organoid epithelial curvature through photoinduced viscoelasticity directs crypt morphogenesis
      Authors: FM Yavitt, BE Kirkpatric, MR Blatchley, KF Speckl, E Mohagheghi, R Moldovan, N Wang, PJ Dempsey, KS Anseth
      Science Advances, 2023-01-20;9(3):eadd5668.
      Species: Mouse
      Sample Types: Whole Tissue
      Applications: Bioassay
    6. Robust induction of primordial germ cells of white rhinoceros on the brink of extinction
      Authors: M Hayashi, V Zywitza, Y Naitou, N Hamazaki, F Goeritz, R Hermes, S Holtze, G Lazzari, C Galli, J Stejskal, S Diecke, TB Hildebrand, K Hayashi
      Science Advances, 2022-12-09;8(49):eabp9683.
      Species: Rhinoceros
      Sample Types: Cell Culture Supernates
      Applications: Bioassay
    7. Embryonic alcohol exposure disrupts the ubiquitin-proteasome system
      Authors: O Weeks, BM Miller, BJ Pepe-Moone, IM Oderberg, SH Freeburg, CJ Smith, TE North, W Goessling
      JCI Insight, 2022-12-08;7(23):.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Cell Culture
    8. Comprehensive microRNA analysis across genome-edited colorectal cancer organoid models reveals miR-24 as a candidate regulator of cell survival
      Authors: JW Villanueva, L Kwong, T Han, SA Martinez, MT Shanahan, M Kanke, LE Dow, CG Danko, P Sethupathy
      BMC Genomics, 2022-12-01;23(1):792.
      Species: Mouse
      Sample Types: Organoid
      Applications: Bioassay
    9. Reprogramming M�ller glia to regenerate ganglion-like cells in adult mouse retina with developmental transcription factors
      Authors: L Todd, W Jenkins, C Finkbeiner, MJ Hooper, PC Donaldson, M Pavlou, J Wohlschleg, N Ingram, F Rieke, TA Reh
      Science Advances, 2022-11-23;8(47):eabq7219.
      Species: Transgenic Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    10. Dual-drug loaded nanomedicine hydrogel as a therapeutic platform to target both residual glioblastoma and glioma stem cells
      Authors: E Bozzato, N Tsakiris, A Paquot, GG Muccioli, C Bastiancic, V Préat
      International journal of pharmaceutics, 2022-10-28;628(0):122341.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    11. Cellular shape reinforces niche to stem cell signaling in the small intestine
      Authors: N Pentinmikk, R Lozano, S Scharaw, S Andersson, JI Englund, D Castillo-A, A Gallagher, M Broberg, KY Song, A Sola Carva, AT Speidel, M Sundstrom, N Allbritton, MM Stevens, OD Klein, A Teixeira, P Katajisto
      Science Advances, 2022-10-14;8(41):eabm1847.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    12. Multiscale light-sheet organoid imaging framework
      Authors: G de Medeiro, R Ortiz, P Strnad, A Boni, F Moos, N Repina, L Challet Me, F Maurer, P Liberali
      Nature Communications, 2022-08-18;13(1):4864.
      Species: Human
      Sample Types: Organoid
      Applications: Cell Culture
    13. Circular EZH2-encoded EZH2-92aa mediates immune evasion in glioblastoma via inhibition of surface NKG2D ligands
      Authors: J Zhong, X Yang, J Chen, K He, X Gao, X Wu, M Zhang, H Zhou, F Xiao, L An, X Wang, Y Shi, N Zhang
      Nature Communications, 2022-08-15;13(1):4795.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    14. Lactate receptor HCAR1 regulates neurogenesis and microglia activation after neonatal hypoxia-ischemia
      Authors: L Kennedy, ER Glesaaen, V Palibrk, M Pannone, W Wang, A Al-Jabri, R Suganthan, N Meyer, ML Austbø, X Lin, LH Bergersen, M Bjørås, JE Rinholm
      Elife, 2022-08-09;11(0):.
      Species: Mouse
      Sample Types: Tissue Homogenates
      Applications: Cell Culture
    15. Induction of potassium channel regulator KCNE4 in a submandibular lymph node metastasis model
      Authors: R Mano, T Tanaka, S Hashiguchi, H Takahashi, N Sakata, S Kondo, S Kodama
      Scientific Reports, 2022-08-01;12(1):13208.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    16. Amphiregulin mediates non-cell-autonomous effect of senescence on reprogramming
      Authors: M von Joest, C Chen, T Douché, J Chantrel, A Chiche, QG Gianetto, M Matondo, H Li
      Oncogene, 2022-07-12;40(2):111074.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    17. Research on the function of the Cend1 regulatory mechanism on p75NTR signaling in spinal cord injury
      Authors: C Chen, Q Yu, Y Huang, XQ Shen, ZZ Ding, GW Chen, J Yan, QG Gu, X Mao
      Neuropeptides, 2022-06-08;95(0):102264.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    18. Single-cell transcriptomics of adult macaque hippocampus reveals neural precursor cell populations
      Authors: ZZ Hao, JR Wei, D Xiao, R Liu, N Xu, L Tang, M Huang, Y Shen, C Xing, W Huang, X Liu, M Xiang, Y Liu, Z Miao, S Liu
      Nature Neuroscience, 2022-05-30;25(6):805-817.
      Species: Rhesus Macaque
      Sample Types: Whole Tissue
      Applications: Bioassay
    19. Towards 3D Bioprinted Spinal Cord Organoids
      Authors: Y Han, M King, E Tikhomirov, P Barasa, CDS Souza, J Lindh, D Baltriukie, L Ferraiuolo, M Azzouz, MR Gullo, EN Kozlova
      International Journal of Molecular Sciences, 2022-05-21;23(10):.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    20. Metabolic determination of cell fate through selective inheritance of mitochondria
      Authors: J Döhla, E Kuuluvaine, N Gebert, A Amaral, JI Englund, S Gopalakris, S Konovalova, AI Nieminen, ES Salminen, R Torregrosa, K Ahlqvist, Y Yang, H Bui, T Otonkoski, R Käkelä, V Hietakanga, H Tyynismaa, A Ori, P Katajisto
      Nature Cell Biology, 2022-02-14;24(2):148-154.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    21. ATM modulates subventricular zone neural stem cell maintenance and senescence through Notch signaling pathway
      Authors: C Dong, X Wang, L Sun, L Zhu, D Yang, S Gao, W Zhang, B Ling, A Liang, Z Gao, J Xu
      Stem Cell Research, 2021-12-07;58(0):102618.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    22. beta-blocker eye drops affect ocular surface through beta2 adrenoceptor of corneal limbal stem cells
      Authors: X Yuan, X Ma, L Yang, Q Zhou, Y Li
      BMC ophthalmology, 2021-12-05;21(1):419.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    23. Loss of H2R signaling disrupts neutrophil homeostasis and promotes inflammation-associated colonic tumorigenesis in mice
      Authors: Z Shi, Y Mori-Akiya, W Du, R Fultz, Y Zhao, W Ruan, S Venable, MA Engevik, J Versalovic
      Cellular and Molecular Gastroenterology and Hepatology, 2021-11-13;0(0):.
      Species: Mouse
      Sample Types: Organoids
      Applications: Bioassay
    24. Efficient stimulation of retinal regeneration from M�ller glia in adult mice using combinations of proneural bHLH transcription factors
      Authors: L Todd, MJ Hooper, AK Haugan, C Finkbeiner, N Jorstad, N Radulovich, CK Wong, PC Donaldson, W Jenkins, Q Chen, F Rieke, TA Reh
      Cell Reports, 2021-10-19;37(3):109857.
      Species: Mouse
      Sample Types: Whole Cell
      Applications: Bioassay
    25. Examining the Developmental Trajectory of an in Vitro Model of Mouse Primordial Germ Cells following Exposure to Environmentally Relevant Bisphenol A Levels
      Authors: SKT Ooi, H Jiang, Y Kang, P Allard
      Environmental health perspectives, 2021-09-29;129(9):97013.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    26. In�vitro reconstitution of the whole male germ-cell development from mouse pluripotent stem cells
      Authors: Y Ishikura, H Ohta, T Sato, Y Murase, Y Yabuta, Y Kojima, C Yamashiro, T Nakamura, T Yamamoto, T Ogawa, M Saitou
      Cell Stem Cell, 2021-09-07;0(0):.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    27. SMAD4 is critical in suppression of BRAF-V600E serrated tumorigenesis
      Authors: K Tong, OA Kothari, KS Haro, A Panda, MM Bandari, JN Carrick, JJ Hur, L Zhang, CS Chan, J Xing, ML Gatza, S Ganesan, MP Verzi
      Oncogene, 2021-08-27;0(0):.
      Species: Mouse
      Sample Types: Organoids
      Applications: Bioassay
    28. ZNRF3 and RNF43 cooperate to safeguard metabolic liver zonation and hepatocyte proliferation
      Authors: T Sun, S Annunziato, S Bergling, C Sheng, V Orsini, P Forcella, M Pikiolek, V Kancherla, S Holwerda, D Imanci, F Wu, LC Meylan, LF Puehringer, A Waldt, M Oertli, S Schuierer, LM Terraccian, S Reinker, H Ruffner, T Bouwmeeste, AW Sailer, E George, G Roma, A de Weck, S Piscuoglio, F Lohmann, U Naumann, P Liberali, F Cong, JS Tchorz
      Cell Stem Cell, 2021-06-14;0(0):.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    29. Formative pluripotent stem cells show features of epiblast cells poised for gastrulation
      Authors: X Wang, Y Xiang, Y Yu, R Wang, Y Zhang, Q Xu, H Sun, ZA Zhao, X Jiang, X Wang, X Lu, D Qin, Y Quan, J Zhang, N Shyh-Chang, H Wang, N Jing, W Xie, L Li
      Cell Research, 2021-02-19;0(0):.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    30. Isolation of PRRX1-positive adult pituitary stem/progenitor cells from the marginal cell layer of the mouse anterior lobe
      Authors: A Shintani, M Higuchi
      Stem Cell Research, 2021-02-02;52(0):102223.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    31. Oligodendrocyte precursor cell specification is regulated by bidirectional neural progenitor-endothelial cell crosstalk
      Authors: I Paredes, JR Vieira, B Shah, CF Ramunno, J Dyckow, H Adler, M Richter, G Schermann, E Giannakour, L Schirmer, HG Augustin, C Ruiz de Al
      Nature Neuroscience, 2021-01-28;0(0):.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    32. Greater epithelial ridge cells are the principal organoid-forming progenitors of the mouse cochlea
      Authors: M Kubota, M Scheibinge, TA Jan, S Heller
      Cell Reports, 2021-01-19;34(3):108646.
      Species: Mouse
      Sample Types: Organoid
      Applications: Bioassay
    33. Inhibition of Gli2 suppresses tumorigenicity in glioblastoma stem cells derived from a de novo murine brain cancer model
      Authors: S Tanigawa, M Fujita, C Moyama, S Ando, H Ii, Y Kojima, T Fujishita, M Aoki, H Takeuchi, T Yamanaka, Y Takahashi, N Hashimoto, S Nakata
      Cancer Gene Therapy, 2021-01-07;0(0):.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    34. Airway-Associated Macrophages in Homeostasis and Repair
      Authors: AE Engler, AB Ysasi, RMF Pihl, C Villacorta, HM Heston, HMK Richardson, BR Thapa, NR Moniz, AC Belkina, SA Mazzilli, JR Rock
      Cell Reports, 2020-12-29;33(13):108553.
    35. Microglia Suppress Ascl1-Induced Retinal Regeneration in Mice
      Authors: L Todd, C Finkbeiner, CK Wong, MJ Hooper, TA Reh
      Cell Reports, 2020-12-15;33(11):108507.
      Species: Transgenic Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    36. Pentraxin 3 contributes to neurogenesis after traumatic brain injury in mice
      Authors: C Zhou, H Chen, JF Zheng, ZD Guo, ZJ Huang, Y Wu, JJ Zhong, XC Sun, CJ Cheng
      Neural Regen Res, 2020-12-01;15(12):2318-2326.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    37. Empty mesoporous silica particles significantly delay disease progression and extend survival in a mouse model of ALS
      Authors: MF Leyton-Jai, P Ivert, J Hoeber, Y Han, A Feiler, C Zhou, S Pankratova, V Shoshan-Ba, A Israelson, EN Kozlova
      Sci Rep, 2020-11-26;10(1):20675.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Cell Culture
    38. Propionate Enhances Cell Speed and Persistence to Promote Intestinal Epithelial Turnover and Repair
      Authors: AJ Bilotta, C Ma, W Yang, Y Yu, Y Yu, X Zhao, Z Zhou, S Yao, SM Dann, Y Cong
      Cell Mol Gastroenterol Hepatol, 2020-11-22;0(0):.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Cell Culture
    39. Telomere dysfunction activates YAP1 to drive tissue inflammation
      Authors: D Chakravart, B Hu, X Mao, A Rashid, J Li, J Li, WT Liao, EM Whitley, P Dey, P Hou, KA LaBella, A Chang, G Wang, DJ Spring, P Deng, D Zhao, X Liang, Z Lan, Y Lin, S Sarkar, C Terranova, YL Deribe, SE Blutt, P Okhuysen, J Zhang, E Vilar, OH Nielsen, A Dupont, M Younes, KR Patel, NF Shroyer, K Rai, MK Estes, YA Wang, AA Bertuch, RA DePinho
      Nat Commun, 2020-09-21;11(1):4766.
      Species: Mouse
      Sample Types: Organoid
      Applications: Bioassay
    40. miR-19b is elevated in peripheral blood of schizophrenic patients and attenuates proliferation of hippocampal neural progenitor cells
      Authors: T Horai, S Boku, S Okazaki, I Otsuka, W Ratta-Apha, K Mouri, N Yamaki, T Hirata, A Hishimoto
      J Psychiatr Res, 2020-09-11;131(0):102-107.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Cell Culture
    41. Genome-wide gene expression analysis of a murine model of prostate cancer progression: Deciphering the roles of IL-6 and p38 MAPK as potential therapeutic targets
      Authors: R Daouk, HF Bahmad, E Saleh, A Monzer, F Ballout, H Kadara, W Abou-Kheir
      PLoS ONE, 2020-08-13;15(8):e0237442.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay, Cell Culture
    42. Sodium-glucose cotransporter 2 inhibition suppresses HIF-1&alpha-mediated metabolic switch from lipid oxidation to glycolysis in kidney tubule cells of diabetic mice
      Authors: T Cai, Q Ke, Y Fang, P Wen, H Chen, Q Yuan, J Luo, Y Zhang, Q Sun, Y Lv, K Zen, L Jiang, Y Zhou, J Yang
      Cell Death Dis, 2020-05-22;11(5):390.
      Species: Human
      Sample Types: Whole Cells
      Applications: Cell Culture
    43. Engraftment potential of maternal adipose-derived stem cells for fetal transplantation
      Authors: A Kawashima, R Yasuhara, R Akino, K Mishima, M Nasu, A Sekizawa
      Heliyon, 2020-03-04;6(3):e03409.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Cell Culture
    44. STAT Signaling Modifies Ascl1 Chromatin Binding and Limits Neural Regeneration from Muller Glia in Adult Mouse Retina
      Authors: NL Jorstad, MS Wilken, L Todd, C Finkbeiner, P Nakamura, N Radulovich, MJ Hooper, A Chitsazan, BA Wilkerson, F Rieke, TA Reh
      Cell Rep, 2020-02-18;30(7):2195-2208.e5.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    45. EGF released from human placental mesenchymal stem cells improves premature ovarian insufficiency via NRF2/HO-1 activation
      Authors: C Ding, Q Zou, Y Wu, J Lu, C Qian, H Li, B Huang
      Aging (Albany NY), 2020-02-10;12(3):2992-3009.
      Species: Mouse
      Sample Types: In Vivo
      Applications: In Vivo
    46. GDNF and GFRalpha1 Are Required for Proper Integration of Adult-Born Hippocampal Neurons
      Authors: A Bonafina, MF Trinchero, AS Ríos, P Bekinschte, AF Schinder, G Paratcha, F Ledda
      Cell Rep, 2019-12-24;29(13):4308-4319.e4.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Cell Culture
    47. Polarizing receptor activation dissociates fibroblast growth factor 2 mediated inhibition of myelination from its neuroprotective potential
      Authors: K Thümmler, E Rom, T Zeis, M Lindner, S Brunner, JJ Cole, D Arseni, S Mücklisch, JM Edgar, N Schaeren-W, A Yayon, C Linington
      Acta Neuropathol Commun, 2019-12-19;7(1):212.
      Species: Mouse, Rat
      Sample Types: Whole Cells
      Applications: Bioassay
    48. TBKBP1 and TBK1 form a growth factor signalling axis mediating immunosuppression and tumourigenesis
      Authors: L Zhu, Y Li, X Xie, X Zhou, M Gu, Z Jie, CJ Ko, T Gao, BE Hernandez, X Cheng, SC Sun
      Nat. Cell Biol., 2019-12-02;21(12):1604-1614.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Cell Culture
    49. Deletion of tetraspanin CD151 alters the Wnt oncogene-induced mammary tumorigenesis: A cell type-linked function and signaling
      Authors: H Li, J Li, R Han, X Deng, J Shi, H Huang, N Hamad, A McCaughley, J Liu, C Wang, K Chen, D Wei, J Qiang, S Thatcher, Y Wu, C Liu, O Thibault, X Wei, S Chen, H Qian, BP Zhou, P Xu, XH Yang
      Neoplasia, 2019-11-26;21(12):1151-1163.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    50. Enteroendocrine progenitor cell enriched miR-7 regulates intestinal epithelial proliferation in an Xiap-dependent manner
      Authors: AP Singh, YH Hung, MT Shanahan, M Kanke, A Bonfini, MK Dame, M Biraud, BCE Peck, OO Oyesola, JM Freund, RL Cubitt, EG Curry, LM Gonzalez, GA Bewick, ED Tait-Wojno, NA Kurpios, S Ding, JR Spence, CM Dekaney, N Buchon, P Sethupathy
      Cell Mol Gastroenterol Hepatol, 2019-11-19;0(0):.
      Species: Mouse
      Sample Types: Whole Tissue
      Applications: Tissue Culture
    51. The panniculus carnosus muscle: A novel model of striated muscle regeneration that exhibits sex differences in the mdx mouse
      Authors: OA Bahri, N Naldaiz-Ga, DC Kennedy, AM Wheatley, A Izeta, KJA McCullagh
      Sci Rep, 2019-11-04;9(1):15964.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    52. Neural stem cell small extracellular vesicle-based delivery of 14-3-3t reduces apoptosis and neuroinflammation following traumatic spinal cord injury by enhancing autophagy by targeting Beclin-1
      Authors: Y Rong, W Liu, C Lv, J Wang, Y Luo, D Jiang, L Li, Z Zhou, W Zhou, Q Li, G Yin, L Yu, J Fan, W Cai
      Aging (Albany NY), 2019-09-28;11(18):7723-7745.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    53. Mist1 Expression is Required for Paneth Cell Maturation
      Authors: CM Dekaney, S King, B Sheahan, J Cortes
      Cell Mol Gastroenterol Hepatol, 2019-07-19;0(0):.
      Species: Mouse
      Sample Types: Whole Tissue
      Applications: Bioassay
    54. Differentiation Induction as a Response to Irradiation in Neural Stem Cells In Vitro
      Authors: J Koní?ová, L Cupal, Š Jarošová, A Michaelide, J Vachelová, M Davídková, P Bart?n?k, M Zíková
      Cancers (Basel), 2019-06-29;11(7):.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    55. Mitochondrial Complex I Function Is Essential for Neural Stem/Progenitor Cells Proliferation and Differentiation
      Authors: D Cabello-Ri, H Sarmiento-, J López-Barn, AM Muñoz-Cabe
      Front Neurosci, 2019-06-26;13(0):664.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    56. Early Seizure Activity Accelerates Depletion of Hippocampal Neural Stem Cells and Impairs Spatial Discrimination in an Alzheimer's Disease Model
      Authors: CH Fu, DM Iascone, I Petrof, A Hazra, X Zhang, MS Pyfer, U Tosi, BF Corbett, J Cai, J Lee, J Park, L Iacovitti, HE Scharfman, G Enikolopov, J Chin
      Cell Rep, 2019-06-25;27(13):3741-3751.e4.
      Species: Mouse, Transgenic Mouse
      Sample Types: Spheroid
      Applications: Bioassay
    57. Local Klotho enhances neuronal progenitor proliferation in the adult hippocampus
      Authors: F Salech, L Varela-Nal, SB Arredondo, DB Bustamante, GA Andaur, R Cisneros, DP Ponce, P Ayala, NC Inestrosa, JL Valdés, MI Behrens, A Couve
      J. Gerontol. A Biol. Sci. Med. Sci., 2019-06-18;0(0):.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    58. Single-Cell Analysis of the Liver Epithelium Reveals Dynamic Heterogeneity and an Essential Role for YAP in Homeostasis and Regeneration
      Authors: BJ Pepe-Moone, MT Dill, A Alemany, J Ordovas-Mo, Y Matsushita, A Rao, A Sen, M Miyazaki, S Anakk, PA Dawson, N Ono, AK Shalek, A van Oudena, FD Camargo
      Cell Stem Cell, 2019-05-09;0(0):.
      Species: Mouse
      Sample Types: Whole Cell
      Applications: Organoid Culture
    59. Neural stem cell-derived small extracellular vesicles attenuate apoptosis and neuroinflammation after traumatic spinal cord injury by activating autophagy
      Authors: Y Rong, W Liu, J Wang, J Fan, Y Luo, L Li, F Kong, J Chen, P Tang, W Cai
      Cell Death Dis, 2019-04-18;10(5):340.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    60. Loss of PKM2 in Lgr5+ intestinal stem cells promotes colitis-associated colorectal cancer
      Authors: Y Kim, YS Lee, SW Kang, S Kim, TY Kim, SH Lee, SW Hwang, J Kim, EN Kim, JS Ju, YY Park, MN Kweon
      Sci Rep, 2019-04-17;9(1):6212.
      Species: Mouse
      Sample Types: Organoids
      Applications: Bioassay
    61. Inhibition of miRNA-27b enhances neurogenesis via AMPK activation in a mouse ischemic stroke model
      Authors: Z Wang, Y Yuan, Z Zhang, K Ding
      FEBS Open Bio, 2019-04-11;9(5):859-869.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    62. Transfer of Functional Cargo in Exomeres
      Authors: Q Zhang, JN Higginboth, DK Jeppesen, YP Yang, W Li, ET McKinley, R Graves-Dea, J Ping, CM Britain, KA Dorsett, CL Hartman, DA Ford, RM Allen, KC Vickers, Q Liu, JL Franklin, SL Bellis, RJ Coffey
      Cell Rep, 2019-04-04;0(0):.
      Species: Mouse
      Sample Types: Organoids
      Applications: Bioassay
    63. Kaiso is required for MTG16-dependent effects on colitis-associated carcinoma
      Authors: SP Short, CW Barrett, KR Stengel, FL Revetta, YA Choksi, LA Coburn, MK Lintel, EM McDonough, MK Washington, KT Wilson, E Prokhortch, X Chen, SW Hiebert, AB Reynolds, CS Williams
      Oncogene, 2019-03-11;0(0):.
      Species: Mouse
      Sample Types:
      Applications: Bioassay
    64. Genetic dissection of Nodal and Bmp signalling requirements during primordial germ cell development in mouse
      Authors: AD Senft, EK Bikoff, EJ Robertson, I Costello
      Nat Commun, 2019-03-06;10(1):1089.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    65. The atypical antipsychotic quetiapine induces hyperlipidemia by activating intestinal PXR signaling
      Authors: Z Meng, T Gwag, Y Sui, SH Park, X Zhou, C Zhou
      JCI Insight, 2019-02-07;4(3):.
      Species: Mouse
      Sample Types:
      Applications: Bioassay
    66. Mitochondrial transfer from mesenchymal stem cells to neural stem cells protects against the neurotoxic effects of cisplatin
      Authors: N Boukelmoun, GS Chiu, A Kavelaars, CJ Heijnen
      Acta Neuropathol Commun, 2018-12-12;6(1):139.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    67. Neuroglobin promotes neurogenesis through Wnt signaling pathway
      Authors: Z Yu, C Cheng, Y Liu, N Liu, EH Lo, X Wang
      Cell Death Dis, 2018-09-20;9(10):945.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    68. Neutrophils Promote Amphiregulin Production in Intestinal Epithelial Cells through TGF-? and Contribute to Intestinal Homeostasis
      Authors: F Chen, W Yang, X Huang, AT Cao, AJ Bilotta, Y Xiao, M Sun, L Chen, C Ma, X Liu, CG Liu, S Yao, SM Dann, Z Liu, Y Cong
      J. Immunol., 2018-08-31;0(0):.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    69. Combinatorial Smad2/3 Activities Downstream of Nodal Signaling Maintain Embryonic/Extra-Embryonic Cell Identities during Lineage Priming
      Authors: AD Senft, I Costello, HW King, AW Mould, EK Bikoff, EJ Robertson
      Cell Rep, 2018-08-21;24(8):1977-1985.e7.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    70. Generation of renewable mouse intestinal epithelial cell monolayers and organoids for functional analyses
      Authors: EC Moorefield, RE Blue, NL Quinney, M Gentzsch, S Ding
      BMC Cell Biol., 2018-08-15;19(1):15.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    71. Direct reprogramming of fibroblasts into neural stem cells by single non-neural progenitor transcription factor Ptf1a
      Authors: D Xiao, X Liu, M Zhang, M Zou, Q Deng, D Sun, X Bian, Y Cai, Y Guo, S Liu, S Li, E Shiang, H Zhong, L Cheng, H Xu, K Jin, M Xiang
      Nat Commun, 2018-07-20;9(1):2865.
      Species: Human
      Sample Types: Whole Cells
      Applications: Bioassay
    72. BVES is required for maintenance of colonic epithelial integrity in experimental colitis by modifying intestinal permeability
      Authors: YA Choksi, VK Reddy, K Singh, CW Barrett, SP Short, B Parang, CE Keating, JJ Thompson, TG Verriere, RE Brown, MB Piazuelo, DM Bader, MK Washington, MK Mittal, T Brand, AP Gobert, LA Coburn, KT Wilson, CS Williams
      Mucosal Immunol, 2018-06-15;0(0):.
      Species: Mouse
      Sample Types: Whole Tissue
      Applications: Bioassay
    73. STAT3 labels a subpopulation of reactive astrocytes required for brain metastasis
      Authors: N Priego, L Zhu, C Monteiro, M Mulders, D Wasilewski, W Bindeman, L Doglio, L Martínez, E Martínez-S, SRY Cajal, D Megías, E Hernández-, C Blanco-Apa, L Martínez, E Zarzuela, J Muñoz, C Fustero-To, E Pineiro, A Hernández-, L Bertero, V Poli, M Sánchez-Ma, JA Menendez, R Soffietti, J Bosch-Barr, M Valiente
      Nat. Med., 2018-06-11;0(0):.
      Species: Human
      Sample Types: Whole Cells
      Applications: Bioassay
    74. Reovirus-Induced Apoptosis in the Intestine Limits Establishment of Enteric Infection
      Authors: JJ Brown, SP Short, J Stencel-Ba, K Urbanek, AJ Pruijssers, N McAllister, M Ikizler, G Taylor, P Aravamudha, S Khomandiak, B Jabri, CS Williams, TS Dermody
      J. Virol., 2018-04-27;0(0):.
      Species: Mouse
      Sample Types: Whole Tissue
      Applications: Bioassay
    75. Loss of Stemness, EMT, and Supernumerary Tooth Formation in Cebpb-/-Runx2+/-Murine Incisors
      Authors: K Saito, K Takahashi, B Huang, M Asahara, H Kiso, Y Togo, H Tsukamoto, S Mishima, M Nagata, M Iida, Y Tokita, M Asai, A Shimizu, T Komori, H Harada, M MacDougall, M Sugai, K Bessho
      Sci Rep, 2018-03-26;8(1):5169.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    76. The protein histidine phosphatase LHPP is a tumour suppressor
      Authors: SK Hindupur, M Colombi, SR Fuhs, MS Matter, Y Guri, K Adam, M Cornu, S Piscuoglio, CKY Ng, C Betz, D Liko, L Quagliata, S Moes, P Jenoe, LM Terraccian, MH Heim, T Hunter, MN Hall
      Nature, 2018-03-21;555(7698):678-682.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    77. Monoclonal Antibodies Reveal Dynamic Plasticity Between Lgr5-�and Bmi1-Expressing Intestinal Cell Populations
      Authors: NR Smith, JR Swain, PS Davies, AC Gallagher, MS Parappilly, CZ Beach, PR Streeter, IA Williamson, ST Magness, MH Wong
      Cell Mol Gastroenterol Hepatol, 2018-03-10;6(1):79-96.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    78. Human amniotic mesenchymal stem cells improve ovarian function in natural aging through secreting hepatocyte growth factor and epidermal growth factor
      Authors: C Ding, Q Zou, F Wang, H Wu, R Chen, J Lv, M Ling, J Sun, W Wang, H Li, B Huang
      Stem Cell Res Ther, 2018-03-09;9(1):55.
      Species: Mouse
      Sample Types: In Vivo
      Applications: In Vivo
    79. The Coordinated Activities of nAChR and Wnt Signaling Regulate Intestinal Stem Cell Function in Mice
      Authors: T Takahashi, A Shiraishi, J Murata
      Int J Mol Sci, 2018-03-05;19(3):.
      Species: Mouse
      Sample Types: Complex Sample Type
      Applications: Bioassay
    80. Zika virus infected primary microglia impairs NPCs proliferation and differentiation
      Authors: J Wang, J Liu, R Zhou, X Ding, Q Zhang, C Zhang, L Li
      Biochem. Biophys. Res. Commun., 2018-02-15;0(0):.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    81. NADsupplementation normalizes key Alzheimer's features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiency
      Authors: Y Hou, S Lautrup, S Cordonnier, Y Wang, DL Croteau, E Zavala, Y Zhang, K Moritoh, JF O'Connell, BA Baptiste, TV Stevnsner, MP Mattson, VA Bohr
      Proc. Natl. Acad. Sci. U.S.A., 2018-02-05;0(0):.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    82. BMP4 signaling in NPCs upregulates Bcl-xL to promote their survival in the presence of FGF-2
      Authors: H Yamamoto, M Kurachi, M Naruse, K Shibasaki, Y Ishizaki
      Biochem. Biophys. Res. Commun., 2018-01-19;0(0):.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    83. Induced haploinsufficiency of Kit receptor tyrosine kinase impairs brain development
      Authors: H Aoki, A Hara, T Kunisada
      JCI Insight, 2017-10-05;2(19):.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    84. Resveratrol Inhibits the Epidermal Growth Factor-Induced Migration of Osteoblasts: the Suppression of SAPK/JNK and Akt
      Authors: T Kawabata, H Tokuda, K Fujita, S Kainuma, G Sakai, R Matsushima, O Kozawa, T Otsuka
      Cell. Physiol. Biochem., 2017-10-02;43(3):1025-1036.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    85. Generation of Mouse Haploid Somatic Cells by Small Molecules for Genome-wide Genetic Screening
      Authors: ZQ He, BL Xia, YK Wang, J Li, GH Feng, LL Zhang, YH Li, HF Wan, TD Li, K Xu, XW Yuan, YF Li, XX Zhang, Y Zhang, L Wang, W Li, Q Zhou
      Cell Rep, 2017-08-29;20(9):2227-2237.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    86. Aging effects on intestinal homeostasis associated with expansion and dysfunction of intestinal epithelial stem cells
      Authors: EC Moorefield, SF Andres, RE Blue, L Van Landeg, AT Mah, MA Santoro, S Ding
      Aging (Albany NY), 2017-08-29;9(8):1898-1915.
      Species: Mouse
      Sample Types: Whole Tissue
      Applications: Bioassay
    87. Epiregulin and EGFR interactions are involved in pain processing
      Authors: LJ Martin, SB Smith, A Khoutorsky, CA Magnussen, A Samoshkin, RE Sorge, C Cho, N Yosefpour, S Sivaselvac, S Tohyama, T Cole, TM Khuong, E Mir, DG Gibson, JS Wieskopf, SG Sotocinal, JS Austin, CB Meloto, JH Gitt, C Gkogkas, N Sonenberg, JD Greenspan, RB Fillingim, R Ohrbach, GD Slade, C Knott, R Dubner, AG Nackley, A Ribeiro-da, GG Neely, W Maixner, DV Zaykin, JS Mogil, L Diatchenko
      J. Clin. Invest., 2017-08-07;0(0):.
      Species: Mouse
      Sample Types: In Vivo
      Applications: In Vivo
    88. Inactivation of STAT3 Signaling Impairs Hair Cell Differentiation in�the�Developing Mouse Cochlea
      Authors: Q Chen, Y Quan, N Wang, C Xie, Z Ji, H He, R Chai, H Li, S Yin, YE Chin, X Wei, WQ Gao
      Stem Cell Reports, 2017-06-29;0(0):.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    89. In vitro expansion of mouse primordial germ cell-like cells recapitulates an epigenetic blank slate
      Authors: H Ohta, K Kurimoto, I Okamoto, T Nakamura, Y Yabuta, H Miyauchi, T Yamamoto, Y Okuno, M Hagiwara, K Shirane, H Sasaki, M Saitou
      EMBO J., 2017-05-30;0(0):.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    90. The p38 signaling pathway mediates quiescence of glioma stem cells by regulating epidermal growth factor receptor trafficking
      Authors: A Soeda, J Lathia, BJ Williams, Q Wu, J Gallagher, A Androutsel, AJ Giles, C Yang, Z Zhuang, MR Gilbert, JN Rich, DM Park
      Oncotarget, 2017-05-16;8(20):33316-33328.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    91. Recruited Monocytes and Type 2 Immunity Promote Lung Regeneration following Pneumonectomy
      Authors: AJ Lechner, IH Driver, J Lee, CM Conroy, A Nagle, RM Locksley, JR Rock
      Cell Stem Cell, 2017-05-11;0(0):.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    92. MicroRNA-27a reduces mutant hutingtin aggregation in an in vitro model of Huntington's disease
      Authors: JJ Ban, JY Chung, M Lee, W Im, M Kim
      Biochem. Biophys. Res. Commun., 2017-05-08;0(0):.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    93. An FAK-YAP-mTOR Signaling Axis Regulates Stem Cell-Based Tissue Renewal in Mice
      Authors: JK Hu, W Du, SJ Shelton, MC Oldham, CM DiPersio, OD Klein
      Cell Stem Cell, 2017-04-27;0(0):.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    94. Activation of muscarinic receptors prevents TNF-?-mediated intestinal epithelial barrier disruption through p38 MAPK
      Authors: J Uwada, T Yazawa, MT Islam, MRI Khan, SM Krug, M Fromm, SI Karaki, Y Suzuki, A Kuwahara, H Yoshiki, K Sada, Muramatsu, T Taniguchi
      Cell. Signal., 2017-04-12;0(0):.
      Species: Human
      Sample Types: Whole Cells
      Applications: Bioassay
    95. Lacking of palladin leads to multiple cellular events changes which contribute to NTD
      Authors: J Tan, XJ Chen, CL Shen, HX Zhang, LY Tang, SY Lu, WT Wu, Y Kuang, J Fei, ZG Wang
      Neural Dev, 2017-03-24;12(1):4.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    96. JMJD3 aids in reprogramming of bone marrow progenitor cells to hepatic phenotype through epigenetic activation of hepatic transcription factors
      Authors: V Kochat, Z Equbal, P Baligar, V Kumar, M Srivastava, A Mukhopadhy
      PLoS ONE, 2017-03-22;12(3):e0173977.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    97. Occludin expression and regulation in small follicles of the layer and broiler breeder hen
      Authors: CS Stephens, PA Johnson
      Gen. Comp. Endocrinol, 2017-02-24;0(0):.
      Species: Chicken
      Sample Types: Whole Cells
      Applications: Bioassay
    98. A Stable but Reversible Integrated Surrogate Reporter for Assaying CRISPR/Cas9-Stimulated Homology-directed Repair
      Authors: Y Wen, G Liao, T Pritchard, TT Zhao, JP Connelly, SM Pruett-Mil, V Blanc, NO Davidson, BB Madison
      J. Biol. Chem, 2017-02-22;0(0):.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    99. Stepwise reprogramming of liver cells to a pancreas progenitor state by the transcriptional regulator Tgif2
      Authors: N Cerdá-Este, H Naumann, S Ruzittu, N Mah, IM Pongrac, C Cozzitorto, A Hommel, MA Andrade-Na, E Bonifacio, FM Spagnoli
      Nat Commun, 2017-02-13;8(0):14127.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    100. Interplay between CCR7 and Notch1 axes promotes stemness in MMTV-PyMT mammary cancer cells
      Authors: ST Boyle, KA Gieniec, CE Gregor, JW Faulkner, SR McColl, M Kochetkova
      Mol. Cancer, 2017-01-31;16(1):19.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    101. CD44 Transmembrane Receptor and Hyaluronan Regulate Adult Hippocampal Neural Stem Cell Quiescence and Differentiation
      Authors: W Su, SC Foster, R Xing, K Feistel, RH Olsen, SF Acevedo, J Raber, LS Sherman
      J. Biol. Chem, 2017-01-31;292(11):4434-4445.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    102. Id2 controls specification of Lgr5+ intestinal stem cell progenitors during gut development
      Authors: L Nigmatulli, M Norkin, MM Dzama, B Messner, S Sayols, N Soshnikova
      EMBO J., 2017-01-11;36(7):869-885.
      Species: Mouse
      Sample Types: Organoid
      Applications: Bioassay
    103. Wnt/?-catenin promotes gastric fundus specification in mice and humans
      Authors: KW McCracken, E Aihara, B Martin, CM Crawford, T Broda, J Treguier, X Zhang, JM Shannon, MH Montrose, JM Wells
      Nature, 2017-01-04;0(0):.
      Species: Mouse
      Sample Types: Whole Tissue
      Applications: Bioassay
    104. Progressive induction of hepatocyte progenitor cells in chronically injured liver
      Authors: N Tanimizu, N Ichinohe, M Yamamoto, H Akiyama, Y Nishikawa, T Mitaka
      Sci Rep, 2017-01-04;7(0):39990.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    105. A cell-autonomous tumour suppressor role of RAF1 in hepatocarcinogenesis
      Nat Commun, 2016-12-21;7(0):13781.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    106. Indispensable role of Notch ligand-dependent signaling in the proliferation and stem cell niche maintenance of APC-deficient intestinal tumors
      Authors: Toru Nakata
      Biochem. Biophys. Res. Commun, 2016-12-08;0(0):.
      Applications: Bioassay
    107. In�Vitro Derivation and Propagation of Spermatogonial Stem Cell Activity from Mouse Pluripotent Stem Cells
      Cell Rep, 2016-12-06;17(10):2789-2804.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    108. Temporal Profiling of Astrocyte Precursors Reveals Parallel Roles for Asef during Development and after Injury
      Authors: Benjamin Deneen
      J. Neurosci., 2016-11-23;36(47):11904-11917.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    109. Quantitative proteomic analysis of age-related subventricular zone proteins associated with neurodegenerative disease
      Sci Rep, 2016-11-18;6(0):37443.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    110. Lack of Diaph3 relaxes the spindle checkpoint causing the loss of neural progenitors
      Nat Commun, 2016-11-16;7(0):13509.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    111. Measuring Cell Viscoelastic Properties Using a Microfluidic Extensional Flow Device
      Authors: Sanjay Kumar
      Biophys. J., 2016-11-01;111(9):2039-2050.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    112. A robust vitronectin-derived peptide for the scalable long-term expansion and neuronal differentiation of human pluripotent stem cell (hPSC)-derived neural progenitor cells (hNPCs)
      Authors: Divya Varun
      Acta Biomater, 2016-10-27;0(0):.
      Species: Human
      Sample Types: Whole Cells
      Applications: Bioassay
    113. The Semaphorin 4D-RhoA-Akt Signal Cascade Regulates Enamel Matrix Secretion in Coordination with Cell Polarization During Ameloblast Differentiation
      J Bone Miner Res, 2016-10-26;0(0):.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    114. Nuclear expression of IL-33 in epidermal keratinocytes promotes wound healing in mice
      Authors: Mamitaro Ohtsuki
      J. Dermatol. Sci., 2016-10-17;0(0):.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    115. Epidermal RAF prevents allergic skin disease
      Elife, 2016-07-19;5(0):.
      Species: Human, Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    116. Sequential Differentiation of Embryonic Stem Cells into Neural Epithelial-Like Stem Cells and Oligodendrocyte Progenitor Cells
      PLoS ONE, 2016-05-18;11(5):e0155227.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    117. Epigenetic profiles signify cell fate plasticity in unipotent spermatogonial stem and progenitor cells
      Nat Commun, 2016-04-27;7(0):11275.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    118. Remission for Loss of Odontogenic Potential in a New Micromilieu In Vitro
      Authors: Y Zheng, J Cai, AP Hutchins, L Jia, P Liu, D Yang, S Chen, L Ge, D Pei, S Wei
      PLoS ONE, 2016-04-06;11(4):e0152893.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    119. Loss of MAX results in meiotic entry in mouse embryonic and germline stem cells
      Authors: A Suzuki, M Hirasaki, T Hishida, J Wu, D Okamura, A Ueda, M Nishimoto, Y Nakachi, Y Mizuno, Y Okazaki, Y Matsui, JC Izpisua Be, A Okuda
      Nat Commun, 2016-03-30;7(0):11056.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    120. The PD-1/B7-H1 pathway modulates the natural killer cells versus mouse glioma stem cells.
      Authors: Huang B, Zhan Y, Zong W, Yu C, Li J, Qu Y, Han S
      PLoS ONE, 2015-08-12;10(8):e0134715.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    121. Fanconi Anemia Mesenchymal Stromal Cells-Derived Glycerophospholipids Skew Hematopoietic Stem Cell Differentiation Through Toll-Like Receptor Signaling.
      Authors: Amarachintha S, Sertorio M, Wilson A, Li X, Pang Q
      Stem Cells, 2015-07-24;33(11):3382-96.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    122. Selenoprotein P influences colitis-induced tumorigenesis by mediating stemness and oxidative damage.
      Authors: Barrett C, Reddy V, Short S, Motley A, Lintel M, Bradley A, Freeman T, Vallance J, Ning W, Parang B, Poindexter S, Fingleton B, Chen X, Washington M, Wilson K, Shroyer N, Hill K, Burk R, Williams C
      J Clin Invest, 2015-06-08;125(7):2646-60.
      Species: Mouse
      Sample Types: Whole Tissue
      Applications: Bioassay
    123. Periostin Promotes Neural Stem Cell Proliferation and Differentiation following Hypoxic-Ischemic Injury.
      Authors: Ma S, Chen L, Lin Y, Yan H, Lv J, Xiong M, Li J, Cheng G, Yang Y, Qiu Z, Zhou W
      PLoS ONE, 2015-04-20;10(4):e0123585.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    124. Compartmentalized accumulation of cAMP near complexes of multidrug resistance protein 4 (MRP4) and cystic fibrosis transmembrane conductance regulator (CFTR) contributes to drug-induced diarrhea.
      Authors: Moon C, Zhang W, Ren A, Arora K, Sinha C, Yarlagadda S, Woodrooffe K, Schuetz J, Valasani K, de Jonge H, Shanmukhappa S, Shata M, Buddington R, Parthasarathi K, Naren A
      J Biol Chem, 2015-03-11;290(18):11246-57.
      Species: Mouse
      Sample Types: Whole Tissue
      Applications: Bioassay
    125. Photodynamic therapy-mediated cancer vaccination enhances stem-like phenotype and immune escape, which can be blocked by thrombospondin-1 signaling through CD47 receptor protein.
      Authors: Zheng Y, Zou F, Wang J, Yin G, Le V, Fei Z, Liu J
      J Biol Chem, 2015-02-19;290(14):8975-86.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    126. The in vitro generation of lung and airway progenitor cells from human pluripotent stem cells.
      Authors: Huang S, Green M, de Carvalho A, Mumau M, Chen Y, D'Souza S, Snoeck H
      Nat Protoc, 2015-02-05;10(3):413-25.
      Species: Human
      Sample Types: Whole Cells
      Applications: Bioassay
    127. Signal transducer and activator of transcription-3 maintains the stemness of radial glia at mid-neurogenesis.
      Authors: Hong S, Song M
      J Neurosci, 2015-01-21;35(3):1011-23.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    128. Distinct functions of epidermal and myeloid-derived VEGF-A in skin tumorigenesis mediated by HPV8.
      Authors: Ding X, Lucas T, Marcuzzi G, Pfister H, Eming S
      Cancer Res, 2014-11-20;75(2):330-43.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    129. Direct lineage conversion of adult mouse liver cells and B lymphocytes to neural stem cells.
      Authors: Cassady J, D'Alessio A, Sarkar S, Dani V, Fan Z, Ganz K, Roessler R, Sur M, Young R, Jaenisch R
      Stem Cell Reports, 2014-11-06;3(6):948-56.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    130. Cell-based therapy for acute and chronic liver failures: distinct diseases, different choices.
      Authors: Sun K, Xie X, Xie J, Jiao S, Chen X, Zhao X, Wang X, Wei L
      Sci Rep, 2014-09-29;4(0):6494.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    131. A novel molecule Me6TREN promotes angiogenesis via enhancing endothelial progenitor cell mobilization and recruitment.
      Authors: Chen H, Wang S, Zhang J, Ren X, Zhang R, Shi W, Lv Y, Zhou Y, Yan X, Chen L, He L, Zhang B, Nan X, Yue W, Li Y, Pei X
      Sci Rep, 2014-08-28;4(0):6222.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    132. Activated CD8+ T lymphocytes inhibit neural stem/progenitor cell proliferation: role of interferon-gamma.
      Authors: Hu S, Rotschafer J, Lokensgard J, Cheeran M
      PLoS ONE, 2014-08-18;9(8):e105219.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    133. Unfolded protein response is required for the definitive endodermal specification of mouse embryonic stem cells via Smad2 and beta-catenin signaling.
      Authors: Xu H, Tsang K, Wang Y, Chan J, Xu G, Gao W
      J Biol Chem, 2014-08-04;289(38):26290-301.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    134. Proinflammatory cytokine-induced tight junction remodeling through dynamic self-assembly of claudins.
      Authors: Capaldo C, Farkas A, Hilgarth R, Krug S, Wolf M, Benedik J, Fromm M, Koval M, Parkos C, Nusrat A
      Mol Biol Cell, 2014-07-16;25(18):2710-9.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    135. Caveolin-1 is required for kinase suppressor of Ras 1 (KSR1)-mediated extracellular signal-regulated kinase 1/2 activation, H-RasV12-induced senescence, and transformation.
      Authors: Kortum R, Fernandez M, Costanzo-Garvey D, Johnson H, Fisher K, Volle D, Lewis R
      Mol Cell Biol, 2014-07-07;34(18):3461-72.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    136. Impact of diet-induced obesity on intestinal stem cells: hyperproliferation but impaired intrinsic function that requires insulin/IGF1.
      Authors: Mah, Amanda T, Van Landeghem, Lauriann, Gavin, Hannah E, Magness, Scott T, Lund, P Kay
      Endocrinology, 2014-06-10;155(9):3302-14.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    137. Hippo pathway activity influences liver cell fate.
      Authors: Yimlamai D, Christodoulou C, Galli G, Yanger K, Pepe-Mooney B, Gurung B, Shrestha K, Cahan P, Stanger B, Camargo F
      Cell, 2014-06-05;157(6):1324-38.
      Species: Mouse
      Sample Types: Whole Tissue
      Applications: Bioassay
    138. Comparing the cultivated cochlear cells derived from neonatal and adult mouse.
      Authors: Lou, Xiangxin, Dong, Youyi, Xie, Jing, Wang, Xianliu, Yang, Lianglia, Tokuda, Masaaki, Zhang, Yanzhong
      J Transl Med, 2014-05-29;12(0):150.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    139. Blockade of TLR3 protects mice from lethal radiation-induced gastrointestinal syndrome.
      Authors: Takemura N, Kawasaki T, Kunisawa J, Sato S, Lamichhane A, Kobiyama K, Aoshi T, Ito J, Mizuguchi K, Karuppuchamy T, Matsunaga K, Miyatake S, Mori N, Tsujimura T, Satoh T, Kumagai Y, Kawai T, Standley D, Ishii K, Kiyono H, Akira S, Uematsu S
      Nat Commun, 2014-03-18;5(0):3492.
      Species: Mouse
      Sample Types: Whole Tissue
      Applications: Bioassay
    140. An enteroendocrine cell-enteric glia connection revealed by 3D electron microscopy.
      Authors: Bohorquez D, Samsa L, Roholt A, Medicetty S, Chandra R, Liddle R
      PLoS ONE, 2014-02-26;9(2):e89881.
      Species: Mouse
      Sample Types: Whole Tissue
      Applications: Bioassay
    141. Efficient generation of lung and airway epithelial cells from human pluripotent stem cells.
      Authors: Huang, Sarah X, Islam, Mohammad, O'Neill, John, Hu, Zheng, Yang, Yong-Gua, Chen, Ya-Wen, Mumau, Melanie, Green, Michael, Vunjak-Novakovic, Gordana, Bhattacharya, Jahar, Snoeck, Hans-Wil
      Nat Biotechnol, 2013-12-01;32(1):84-91.
      Species: Human
      Sample Types: Whole Cells
      Applications: Bioassay
    142. Knockdown of TrkA in cumulus oocyte complexes (COCs) inhibits EGF-induced cumulus expansion by down-regulation of IL-6.
      Authors: Wang Y, Liang N, Yao G, Tian H, Zhai Y, Yin Y, Sun F
      Mol Cell Endocrinol, 2013-11-08;382(2):804-13.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    143. Induction of intestinal stem cells by R-spondin 1 and Slit2 augments chemoradioprotection.
      Authors: Zhou, Wei-Jie, Geng, Zhen H, Spence, Jason R, Geng, Jian-Guo
      Nature, 2013-07-31;501(7465):107-11.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Cell Culture
    144. Reprogramming fibroblasts into bipotential hepatic stem cells by defined factors.
      Authors: Yu B, He Z, You P, Han Q, Xiang D, Chen F, Wang M, Liu C, Lin X, Borjigin U, Zi X, Li J, Zhu H, Li W, Han C, Wangensteen K, Shi Y, Hui L, Wang X, Hu Y
      Cell Stem Cell, 2013-07-18;13(3):328-40.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    145. Co-culture of neural crest stem cells (NCSC) and insulin producing beta-TC6 cells results in cadherin junctions and protection against cytokine-induced beta-cell death.
      Authors: Ngamjariyawat A, Turpaev K, Vasylovska S, Kozlova E, Welsh N
      PLoS ONE, 2013-04-17;8(4):e61828.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    146. MicroRNA-17-92 cluster mediates the proliferation and survival of neural progenitor cells after stroke.
      Authors: Liu, Xian Shu, Chopp, Michael, Wang, Xin Li, Zhang, Li, Hozeska-Solgot, Ann, Tang, Tao, Kassis, Haifa, Zhang, Rui Lan, Chen, Charles, Xu, Jennifer, Zhang, Zheng Ga
      J Biol Chem, 2013-03-19;288(18):12478-88.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    147. Single transcription factor reprogramming of hair follicle dermal papilla cells to induced pluripotent stem cells.
      Authors: Tsai SY, Bouwman BA, Ang YS, Kim SJ, Lee DF, Lemischka IR, Rendl M
      Stem Cells, 2011-06-01;29(6):964-71.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    148. Human embryonic and rat adult stem cells with primitive endoderm-like phenotype can be fated to definitive endoderm, and finally hepatocyte-like cells.
      Authors: Roelandt P, Pauwelyn KA, Sancho-Bru P
      PLoS ONE, 2010-08-11;5(8):e12101.
      Species: Rat
      Sample Types: Whole Cells
      Applications: Cell Culture
    149. Primary gene-engineered neural stem/progenitor cells demonstrate tumor-selective migration and antitumor effects in glioma.
      Authors: Mercapide J, Rappa G, Anzanello F
      Int. J. Cancer, 2010-03-01;126(5):1206-15.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    150. Reduced EGFR causes abnormal valvular differentiation leading to calcific aortic stenosis and left ventricular hypertrophy in C57BL/6J but not 129S1/SvImJ mice.
      Authors: Barrick CJ, Roberts RB, Rojas M, Rajamannan NM, Suitt CB, O'Brien KD, Smyth SS, Threadgill DW
      Am. J. Physiol. Heart Circ. Physiol., 2009-05-15;297(1):H65-75.
      Species: Mouse
      Sample Types: In Vivo
      Applications: In Vivo
    151. Isolation and characterization of neural stem/progenitor cells from post-stroke cerebral cortex in mice.
      Authors: Nakagomi T, Taguchi A, Fujimori Y, Saino O, Nakano-Doi A, Kubo S, Gotoh A, Soma T, Yoshikawa H, Nishizaki T, Nakagomi N, Stern DM, Matsuyama T
      Eur. J. Neurosci., 2009-04-17;29(0):1842-52.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    152. Toll-like receptor 3 is a negative regulator of embryonic neural progenitor cell proliferation.
      Authors: Lathia JD, Okun E, Tang SC, Griffioen K, Cheng A, Mughal MR, Laryea G, Selvaraj PK, Ffrench-Constant C, Magnus T, Arumugam TV, Mattson MP
      J. Neurosci., 2008-12-17;28(51):13978-84.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    153. Thalidomide inhibits epidermal growth factor-induced cell growth in mouse and human monocytic leukemia cells via Ras inactivation.
      Authors: Noman AS, Koide N, Khuda II, Dagvadorj J, Tumurkhuu G, Naiki Y, Komatsu T, Yoshida T, Yokochi T
      Biochem. Biophys. Res. Commun., 2008-07-26;374(4):683-7.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    154. Binding of ras to phosphoinositide 3-kinase p110alpha is required for ras-driven tumorigenesis in mice.
      Authors: Gupta S, Ramjaun AR, Haiko P, Wang Y, Warne PH, Nicke B, Nye E, Stamp G, Alitalo K, Downward J
      Cell, 2007-06-01;129(5):957-68.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    155. Bcl-XL/Bax proteins direct the fate of embryonic cortical precursor cells.
      Authors: Chang MY, Sun W, Ochiai W, Nakashima K, Kim SY, Park CH, Kang JS, Shim JW, Jo AY, Kang CS, Lee YS, Kim JS, Lee SH
      Mol. Cell. Biol., 2007-04-16;27(12):4293-305.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    156. Bone morphogenetic protein-mediated modulation of lineage diversification during neural differentiation of embryonic stem cells.
      Authors: Gossrau G, Thiele J, Konang R, Schmandt T, Brustle O
      Stem Cells, 2007-01-11;25(4):939-49.
      Species: Mouse
      Sample Types: Whole Cells
      Applications: Bioassay
    157. EphB4 provides survival advantage to squamous cell carcinoma of the head and neck.
      Authors: Masood R, Kumar SR, Sinha UK, Crowe DL, Krasnoperov V, Reddy RK, Zozulya S, Singh J, Xia G, Broek D, Schonthal AH, Gill PS
      Int. J. Cancer, 2006-09-15;119(6):1236-48.
      Species: Human
      Sample Types: Whole Cells
      Applications: Bioassay
    158. Cardiac arterial pole alignment is sensitive to FGF8 signaling in the pharynx.
      Authors: Hutson MR, Zhang P, Stadt HA, Sato AK, Li YX, Burch J, Creazzo TL, Kirby ML
      Dev. Biol., 2006-06-12;295(2):486-97.
      Species: Chicken
      Sample Types: Whole Cells
      Applications: Bioassay

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    Recombinant Mouse EGF Protein, CF
    By Pablo Hurtado on 05/28/2020
    Application: In vitro bioactivity in cell culture
    Recombinant Mouse EGF Protein, CF
    By Oonagh Paerewijck on 08/14/2018
    Application: CellProlif

    culture of murine intestinal cel line
    10 ng/ml EGF

    Cell Proliferation Recombinant Mouse EGF Protein, CF 2028-EG
    Recombinant Mouse EGF Protein, CF
    By Anonymous on 05/16/2017
    Application: Stem/Immune cell maintenance or differentiation
    Reason for Rating: No problems, used to grow spermatogonial stem cells.
    Recombinant Mouse EGF Protein, CF
    By Anonymous on 04/19/2017
    Application: In vitro bioactivity in cell culture

    Growth of B-16 Mouse melanoma cells as spheroids in serum-free medium after treatment with Recombinant Mouse EGF protein (#2028-EG) for 48 hours.

    In vitro bioactivity in cell culture Recombinant Mouse EGF Protein, CF 2028-EG
    Recombinant Mouse EGF Protein, CF
    By Catherine Kurtz on 05/16/2016
    Recombinant Mouse EGF Protein, CF 2028-EG