Recombinant Mouse GM-CSF Protein Summary
Product Specifications
Ala18-Lys141, with an N-terminal Met
Analysis
Product Datasheets
Carrier Free
CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. The carrier free version does not contain BSA.
In general, we advise purchasing the recombinant protein with BSA for use in cell or tissue culture, or as an ELISA standard. In contrast, the carrier free protein is recommended for applications, in which the presence of BSA could interfere.
415-ML
Formulation | Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein. *1 mg pack size (01M) is supplied as a 0.2 µm filtered solution in PBS with BSA as a carrier protein. |
Reconstitution | Reconstitute at 100 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin. |
Shipping | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
Stability & Storage: | Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
|
415-ML/CF
Formulation | Lyophilized from a 0.2 μm filtered solution in PBS. |
Reconstitution | Reconstitute at 100 μg/mL in sterile PBS. |
Shipping | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
Stability & Storage: | Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
|
Scientific Data
Recombinant Mouse GM-CSF (Catalog # 415-ML) stimulates cell proliferation of the DA3 mouse myeloma cell line. The ED50 for this effect is 5-30 pg/mL.
1 μg/lane of Recombinant Mouse GM-CSF was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 14 kDa.
Reconstitution Calculator
Background: GM-CSF
GM-CSF was initially characterized as a factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. It is also a growth factor for erythroid, megakaryocyte, and eosinophil progenitors. GM-CSF is produced by a number of different cell types (including T cells, B cells, macrophages, mast cells, endothelial cells, fibroblasts, and adipocytes) in response to cytokine or inflammatory stimuli. On mature hematopoietic cells, GM-CSF is a survival factor for and activates the effector functions of granulocytes, monocytes/macrophages, and eosinophils (1, 2). GM-CSF promotes a Th1 biased immune response, angiogenesis, allergic inflammation, and the development of autoimmunity (3-5). It shows clinical effectiveness in ameliorating chemotherapy-induced neutropenia, and GM-CSF transfected tumor cells are utilized as cancer vaccines (6, 7). The 22 kDa glycosylated GM-CSF, similar to IL-3 and IL-5, is a cytokine with a core of four bundled alpha ‑helices (8-10). Mature mouse GM-CSF shares 49%-54% amino acid sequence identity with canine, feline, human, and porcine GM-CSF and 69% with rat GM‑CSF. GM‑CSF exerts its biological effects through a heterodimeric receptor complex composed of GM-CSF R alpha /CD116 and the signal transducing common beta chain (CD131) which is also a component of the high-affinity receptors for IL-3 and IL-5 (11, 12). In addition, GM-CSF binds a naturally occurring soluble form of GM-CSF R alpha (13). The activity of GM-CSF is species specific between human and mouse. Mouse GM-CSF is only weakly active on rat cells, although rat GM‑CSF is fully active on mouse cells (14, 15).
- Martinez-Moczygemba, M. and D.P. Huston (2003) J. Allergy Clin. Immunol. 112:653.
- Barreda, D.R. et al. (2004) Dev. Comp. Immunol. 28:509.
- Eksioglu, E.A. et al. (2007) Exp. Hematol. 35:1163.
- Cao, Y. (2007) J. Clin. Invest. 117:2362.
- Fleetwood, A.J. et al. (2005) Crit. Rev. Immunol. 25:405.
- Heuser, M. et al. (2007) Semin. Hematol. 44:148.
- Hege, K.M. et al. (2006) Int. Rev. Immunol. 25:321.
- Kaushansky, K. et al. (1992) Biochemistry 31:1881.
- Diederichs, K. et al. (1991) Science 254:1779.
- Gough, N.M. et al. (1984) Nature 309:763.
- Onetto-Pothier, N. et al. (1990) Blood 75:59.
- Hayashida, K. et al. (1990) Proc. Natl. Acad. Sci. 87:9655.
- Pelley, J.L. et al. (2007) Exp. Hematol. 35:1483.
- Oaks, M.K. et al. (1995) J. Interferon Cytokine Res. 15:1095.
- Vandenabeele, P. et al. (1990) Lymphokine Res. 9:381.
Citations for Recombinant Mouse GM-CSF Protein
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 10
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Dendritic Cell - Fibroblast Crosstalk via TLR9 and AHR Signaling Drives Lung Fibrogenesis
Authors: Carter, H;Costa, RM;Adams, TS;Gilchrist, T;Emch, CE;Bame, M;Oldham, JM;Linderholm, AL;Noth, I;Kaminski, N;Moore, BB;Gurczynski, SJ;
bioRxiv : the preprint server for biology
Species: Murine polyomavirus strain A3
Sample Types: Whole Cells
Applications: Bioassay -
Fine tuning of CpG spatial distribution with DNA origami for improved cancer vaccination
Authors: Zeng, YC;Young, OJ;Wintersinger, CM;Anastassacos, FM;MacDonald, JI;Isinelli, G;Dellacherie, MO;Sobral, M;Bai, H;Graveline, AR;Vernet, A;Sanchez, M;Mulligan, K;Choi, Y;Ferrante, TC;Keskin, DB;Fell, GG;Neuberg, D;Wu, CJ;Mooney, DJ;Kwon, IC;Ryu, JH;Shih, WM;
Nature nanotechnology
Species: Murine polyomavirus strain A3
Sample Types: Whole Cells
Applications: Bioassay -
Krüppel-like Factor (KLF) family members control expression of genes required for serous cavity and alveolar macrophage identities
Authors: Pestal, K;Slayden, LC;Barton, GM;
bioRxiv : the preprint server for biology
Species: Viral, Murine polyomavirus strain A3
Sample Types: Whole Cells
Applications: Bioassay -
Mycobacteria modulate SUMOylation to suppresses protective responses in dendritic cells
Authors: Anang, V;Singh, A;Kumar Rana, A;Saraswati, SSK;Bandyopadhyay, U;Verma, C;Chadha, A;Natarajan, K;
PloS one
Species: Human
Sample Types:
Applications: Cell Culture -
Spleen-targeted neoantigen DNA vaccine for personalized immunotherapy of hepatocellular carcinoma
Authors: Wu, M;Luo, Z;Cai, Z;Mao, Q;Li, Z;Li, H;Zhang, C;Zhang, Y;Zhong, A;Wu, L;Liu, X;
EMBO molecular medicine
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture -
Tumor-derived semaphorin 4A improves PD-1-blocking antibody efficacy by enhancing CD8+ T cell cytotoxicity and proliferation
Authors: Naito, Y;Koyama, S;Masuhiro, K;Hirai, T;Uenami, T;Inoue, T;Osa, A;Machiyama, H;Watanabe, G;Sax, N;Villa, J;Kinugasa-Katayama, Y;Nojima, S;Yaga, M;Hosono, Y;Okuzaki, D;Satoh, S;Tsuda, T;Nakanishi, Y;Suga, Y;Morita, T;Fukushima, K;Nishide, M;Shiroyama, T;Miyake, K;Iwahori, K;Hirata, H;Nagatomo, I;Yano, Y;Tamiya, M;Kumagai, T;Takemoto, N;Inohara, H;Yamasaki, S;Yamashita, K;Aoshi, T;Akbay, EA;Hosen, N;Shintani, Y;Takamatsu, H;Mori, M;Takeda, Y;Kumanogoh, A;
Science advances
Species: Transgenic Mouse, Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Distinct Th17 effector cytokines differentially promote microglial and blood-brain barrier inflammatory responses during post-infectious encephalitis
Authors: Wayne, CR;Bremner, L;Faust, TE;Dur�n-Laforet, V;Ampatey, N;Ho, SJ;Feinberg, PA;Arvanitis, P;Ciric, B;Ruan, C;Elyaman, W;Delaney, SL;Vargas, WS;Swedo, S;Menon, V;Schafer, DP;Cutforth, T;Agalliu, D;
bioRxiv : the preprint server for biology
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture -
Hypoxia-inducible factor orchestrates adenosine metabolism to promote liver cancer development
Authors: Cheu, JW;Chiu, DK;Kwan, KK;Yang, C;Yuen, VW;Goh, CC;Chui, NN;Shen, W;Law, CT;Li, Q;Zhang, MS;Bao, MH;Wong, BP;Chan, CY;Liu, CX;Sit, GF;Ooi, ZY;Deng, H;Tse, AP;Ng, IO;Wong, CC;
Science advances
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
The Chemokine Receptor CCR1 Mediates Microglia Stimulated Glioma Invasion
Authors: N Zeren, Z Afzal, S Morgan, G Marshall, M Uppiliappa, J Merritt, SJ Coniglio
International Journal of Molecular Sciences, 2023-03-07;24(6):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
IL-27 Signaling Promotes Th1 Response by Downregulating IL-10 Production in DCs during Chlamydial Respiratory Infection
Authors: J Zeng, S Yang, Y Tuo, X Zha, R Sun, T Lu, H Zhang, L Tan, S Qiao, H Bai
Microorganisms, 2023-02-27;11(3):.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture -
CCR7 Mediates Dendritic-Cell-Derived Exosome Migration and Improves Cardiac Function after Myocardial Infarction
Authors: Y Zhang, W Gao, J Yuan, X Zhong, K Yao, R Luo, H Liu
Pharmaceutics, 2023-01-30;15(2):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Influence of PEG Chain Length of Functionalized Magnetic Nanoparticles on the Cytocompatibility and Immune Competence of Primary Murine Macrophages and Dendritic Cells
Authors: R Storjohann, B Gericke, J Reifenrath, T Herrmann, P Behrens, H Oltmanns, J Mei beta ner
International Journal of Molecular Sciences, 2023-01-29;24(3):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Galectin-7 reprograms skin carcinogenesis by fostering innate immune evasive programs
Authors: NA Pinto, MC Abba, L Laporte, JM Pérez Sáez, AG Blidner, NI Torres, RM Morales, SG Gatto, CA Bach, F Veigas, HJ García Riv, P Song, JH Frederikse, LJ Rasmussen, F Poirier, DO Croci, V Sundblad, GA Rabinovich, JP Cerliani
Cell Death and Differentiation, 2023-01-24;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Strain-specific alterations in gut microbiome and host immune responses elicited by tolerogenic Bifidobacterium pseudolongum
Authors: B Ma, SJ Gavzy, V Saxena, Y Song, W Piao, HW Lwin, R Lakhan, J Lyyathurai, L Li, M France, C Paluskievi, MW Shirkey, L Hittle, A Munawwar, EF Mongodin, JS Bromberg
Scientific Reports, 2023-01-19;13(1):1023.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture -
Glycosyltransferase Extl1 promotes CCR7-mediated dendritic cell migration to restrain infection and autoimmunity
Authors: J Liu, Y Cheng, X Zhang, Y Chen, H Zhu, K Chen, S Liu, Z Li, X Cao
Cell Reports, 2023-01-18;42(1):111991.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
A Novel Engineered AAV-based Neoantigen Vaccine in Combination with Radiotherapy Eradicates Tumors
Authors: KC Huang, CY Lai, WZ Hong, HY Chang, PC Lin, SF Chiang, TW Ke, JA Liang, AC Shiau, PC Yang, WT Chen, KSC Chao
Cancer Immunology Research, 2023-01-03;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Influence of PEG Chain Length of Functionalized Magnetic Nanoparticles on the Cytocompatibility and Immune Competence of Primary Murine Macrophages and Dendritic Cells
Authors: R Storjohann, B Gericke, J Reifenrath, T Herrmann, P Behrens, H Oltmanns, J Mei beta ner
International Journal of Molecular Sciences, 2023;24(3):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Nanoparticle delivery of CD40 siRNA suppresses alloimmune responses by inhibiting activation and differentiation of DCs and macrophages
Authors: J Wang, K Mao, X Cong, H Tan, C Wu, Z Hu, YG Yang, T Sun
Science Advances, 2022-12-21;8(51):eabq3699.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture -
IMPDH inhibition activates TLR-VCAM1 pathway and suppresses the development of MLL-fusion leukemia
Authors: X Liu, N Sato, T Yabushita, J Li, Y Jia, M Tamura, S Asada, T Fujino, T Fukushima, T Yonezawa, Y Tanaka, T Fukuyama, A Tsuchiya, S Shikata, H Iwamura, C Kinouchi, K Komatsu, S Yamasaki, T Shibata, AT Sasaki, J Schibler, M Wunderlich, E O'Brien, B Mizukawa, JC Mulloy, Y Sugiura, H Takizawa, T Shibata, K Miyake, T Kitamura, S Goyama
Embo Molecular Medicine, 2022-12-01;0(0):e15631.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture -
Chronic exposure to carbon black ultrafine particles reprograms macrophage metabolism and accelerates lung cancer
Authors: CY Chang, R You, D Armstrong, A Bandi, YT Cheng, PM Burkhardt, L Becerra-Do, MC Madison, HY Tung, Z Zeng, Y Wu, L Song, PE Phillips, P Porter, JM Knight, N Putluri, X Yuan, DC Marcano, EA McHugh, JM Tour, A Catic, L Maneix, BM Burt, HS Lee, DB Corry, F Kheradmand
Science Advances, 2022-11-16;8(46):eabq0615.
Species: Transgenic Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Adoptive therapy with amyloid-beta specific regulatory T cells alleviates Alzheimer's disease
Authors: H Yang, SY Park, H Baek, C Lee, G Chung, X Liu, JH Lee, B Kim, M Kwon, H Choi, HJ Kim, JY Kim, Y Kim, YS Lee, G Lee, SK Kim, JS Kim, YT Chang, WS Jung, KH Kim, H Bae
Theranostics, 2022-11-07;12(18):7668-7680.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Glutamyl-prolyl-tRNA synthetase 1 coordinates early endosomal anti-inflammatory AKT signaling
Authors: EY Lee, SM Kim, JH Hwang, SY Jang, S Park, S Choi, GS Lee, J Hwang, JH Moon, PL Fox, S Kim, CH Lee, MH Kim
Nature Communications, 2022-10-29;13(1):6455.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Intraperitoneal injection of class A TLR9 agonist enhances anti-PD-1 immunotherapy in colorectal peritoneal metastases
Authors: T Jiang, H Zhang, Y Li, P Jayakumar, H Liao, H Huang, TR Billiar, M Deng
JCI Insight, 2022-10-24;7(20):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Interferon-gamma Stimulates Interleukin-27 Derived from Dendritic Cells to Regulate Th9 Differentiation through STAT1/3 Pathway
Authors: P Xiong, T Liu, Y Chen, Q Xu, X Hu, F Han, L Shi
Disease Markers, 2022-10-18;2022(0):1542112.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
A Novel Approach to Vaccine Development: Concomitant Pathogen Inactivation and Host Immune Stimulation by Peroxynitrite
Authors: S Rotem, E Bar-Haim, U Elia, H Cohen, S Lazar, O Cohen, T Chitlaru, Y Gal
Vaccines, 2022-09-22;10(10):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Nascent RHOH acts as a molecular brake on actomyosin-mediated effector functions of inflammatory neutrophils
Authors: S Peng, D Stojkov, J Gao, K Oberson, P Latzin, C Casaulta, S Yousefi, HU Simon
PloS Biology, 2022-09-15;20(9):e3001794.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Trem2 deletion enhances tau dispersion and pathology through microglia exosomes
Authors: B Zhu, Y Liu, S Hwang, K Archuleta, H Huang, A Campos, R Murad, J Piña-Cresp, H Xu, TY Huang
Molecular Neurodegeneration, 2022-09-02;17(1):58.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
CLEC5A is critical in Pseudomonas aeruginosa-induced acute lung injury
Authors: PS Sung, YC Peng, SP Yang, CH Chiu, SL Hsieh
JCI Insight, 2022-09-01;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Ablation of Siglec-E augments brain inflammation and ischemic injury
Authors: L Li, Y Chen, MN Sluter, R Hou, J Hao, Y Wu, GY Chen, Y Yu, J Jiang
Journal of Neuroinflammation, 2022-07-20;19(1):191.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Interactions between copper homeostasis and the fungal cell wall affect copper stress resistance
Authors: C Probst, S Garcia-San, JT Brooks, I Van Der Kl, O Baars, M Ralle, DJ Thiele, JA Alspaugh
PloS Pathogens, 2022-06-23;18(6):e1010195.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Deciphering the immunopeptidome in vivo reveals new tumour antigens
Authors: AM Jaeger, LE Stopfer, R Ahn, EA Sanders, DA Sandel, WA Freed-Past, WM Rideout, S Naranjo, T Fessenden, KB Nguyen, PS Winter, RE Kohn, PMK Westcott, JM Schenkel, SL Shanahan, AK Shalek, S Spranger, FM White, T Jacks
Nature, 2022-06-15;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Far infrared light irradiation enhances Abeta clearance via increased exocytotic microglial ATP and ameliorates cognitive deficit in Alzheimer's disease-like mice
Authors: Q Li, J Peng, Y Luo, J Zhou, T Li, L Cao, S Peng, Z Zuo, Z Wang
Journal of Neuroinflammation, 2022-06-14;19(1):145.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Neuroprotective effects of ex vivo-expanded regulatory T cells on trimethyltin-induced neurodegeneration in mice
Authors: SY Park, H Yang, M Ye, X Liu, I Shim, YT Chang, H Bae
Journal of Neuroinflammation, 2022-06-11;19(1):143.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Immunization using ApoB-100 peptide-linked nanoparticles reduces atherosclerosis
Authors: KY Chyu, X Zhao, J Zhou, PC Dimayuga, NW Lio, B Cercek, NT Trac, EJ Chung, PK Shah
JCI Insight, 2022-06-08;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Lack of Functional P110delta Affects Expression of Activation Marker CD80 but Does Not Influence Functions of Neutrophils
Authors: A Manda-Hand, A Mroczek, W Ku?micka, A Cieloch, Z Homoncik, A Muchowicz, U Demkow, M Wachowska
International Journal of Molecular Sciences, 2022-06-07;23(12):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
PD-L1 signaling selectively regulates T cell lymphatic transendothelial migration
Authors: W Piao, L Li, V Saxena, J Iyyathurai, R Lakhan, Y Zhang, IT Lape, C Paluskievi, KL Hippen, Y Lee, E Silverman, MW Shirkey, LV Riella, BR Blazar, JS Bromberg
Nature Communications, 2022-04-21;13(1):2176.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Type I interferon antagonism of the JMJD3-IRF4 pathway modulates macrophage activation and polarization
Authors: K Ming-Chin, AA Achuthan, DP De Souza, TJ Lupancu, KJ Binger, MKS Lee, Y Xu, MJ McConville, NA de Weerd, D Dragoljevi, PJ Hertzog, AJ Murphy, JA Hamilton, AJ Fleetwood
Cell Reports, 2022-04-19;39(3):110719.
Species: Mouse
Sample Types: In Vivo, Whole Cells
Applications: Bioassay, In Vivo -
Self-assembled BPIV3 nanoparticles can induce comprehensive immune responses and protection against BPIV3 challenge by inducing dendritic cell maturation in mice
Authors: Z Qu, M Li, R An, H Dai, Y Yu, C Li, C Cao, Y Meng, J Wang, M Gao
Veterinary Microbiology, 2022-03-31;268(0):109415.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Bladder Cancer Extracellular Vesicles Elicit a CD8 T Cell-Mediated Antitumor Immunity
Authors: CJ Ortiz-Boni, TP Uccello, SA Gerber, EM Lord, EM Messing, YF Lee
International Journal of Molecular Sciences, 2022-03-08;23(6):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Glycosite-deleted mRNA of SARS-CoV-2 spike protein as a broad-spectrum vaccine
Authors: CY Wu, CW Cheng, CC Kung, KS Liao, JT Jan, C Ma, CH Wong
Proceedings of the National Academy of Sciences of the United States of America, 2022-03-01;119(9):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Commensal oral microbiota induces osteoimmunomodulatory effects separate from systemic microbiome in mice
Authors: JD Hathaway-S, JD Aartun, NA Poulides, MB Kuhn, BE McCormick, ME Chew, E Huang, RP Darveau, C Westwater, CM Novince
JCI Insight, 2022-02-22;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
The Modulatory Effects of DMF on Microglia in Aged Mice Are Sex-Specific
Authors: V Mela, A Sayd Gaban, E O'Neill, S Bechet, A Walsh, MA Lynch
Cells, 2022-02-18;11(4):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
GM-CSF perturbs cell identity in mouse pre-implantation embryos
Authors: T Pock, K Schulte, S Schlatt, M Boiani, V Nordhoff
PLoS ONE, 2022-02-10;17(2):e0263793.
Species: Mouse
Sample Types: Embryos
Applications: Bioassay -
GM-CSF Promotes Immune Response and Survival in a Mouse Model of COVID-19
Authors: H Potter, L Kendall, T Boyd, S Sillau, A Bosco-Laut, N Markham, D Fong, P Clarke, K Tyler
Research square, 2022-01-26;0(0):.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo -
Interactions of Both Pathogenic and Nonpathogenic CUG Clade Candida Species with Macrophages Share a Conserved Transcriptional Landscape
Authors: AW Pountain, JR Collette, WM Farrell, MC Lorenz
MBio, 2021-12-14;12(6):e0331721.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Immunosuppressive effect of Columbianadin on maturation, migration, allogenic T cell stimulation and phagocytosis capacity of TNF-alpha induced dendritic cells
Authors: S Chen, Y Bai, Y Wang, C Liang, K Du, S Wang, J Li, YX Chang
Journal of ethnopharmacology, 2021-12-14;285(0):114918.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Identification of the minimal active soluble TREM2 sequence for modulating microglial phenotypes and amyloid pathology
Authors: X Sheng, Y Yao, R Huang, Y Xu, Y Zhu, L Chen, L Zhang, W Wang, R Zhuo, D Can, CF Chang, YW Zhang, H Xu, G Bu, L Zhong, XF Chen
Journal of Neuroinflammation, 2021-12-10;18(1):286.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Microglial-stimulation of glioma invasion involves the EGFR ligand amphiregulin
Authors: SJ Coniglio, JE Segall
PLoS ONE, 2021-11-29;16(11):e0260252.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Transcriptomic Analysis of the Effects of Chemokine Receptor CXCR3 Deficiency on Immune Responses in the Mouse Brain during Toxoplasma gondii Infection
Authors: K Umeda, Y Goto, K Watanabe, N Ushio, RM Fereig, F Ihara, S Tanaka, Y Suzuki, Y Nishikawa
Microorganisms, 2021-11-12;9(11):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Nuclear-localized human respiratory syncytial virus NS1 protein modulates host gene transcription
Authors: J Pei, NR Beri, AJ Zou, P Hubel, HK Dorando, V Bergant, RD Andrews, J Pan, JM Andrews, KCF Sheehan, A Pichlmair, GK Amarasingh, SL Brody, JE Payton, DW Leung
Cell Reports, 2021-10-12;37(2):109803.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Gut microbiota-mediated secondary bile acids regulate dendritic cells to attenuate autoimmune uveitis through TGR5 signaling
Authors: J Hu, C Wang, X Huang, S Yi, S Pan, Y Zhang, G Yuan, Q Cao, X Ye, H Li
Cell Reports, 2021-09-21;36(12):109726.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Tonic prime-boost of STING signalling mediates Niemann-Pick disease type C
Authors: TT Chu, X Tu, K Yang, J Wu, JJ Repa, N Yan
Nature, 2021-07-21;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Single Amino Acid Deletion at N-Terminus of the Target Antigen in DNA Vaccine Induces Altered CD8+ T Cell Responses against Tumor Antigen
Authors: T Imai
Vaccines, 2021-05-21;9(6):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Pharmacological Wnt ligand inhibition overcomes key tumor-mediated resistance pathways to anti-PD-1 immunotherapy
Authors: NC DeVito, M Sturdivant, B Thievanthi, C Xiao, MP Plebanek, AKS Salama, GM Beasley, A Holtzhause, V Novotny-Di, JH Strickler, BA Hanks
Cell Reports, 2021-05-04;35(5):109071.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Activation of 4-1BB signaling in bone marrow stromal cells triggers bone loss via the p-38 MAPK-DKK1 axis in aged mice
Authors: D Wan, S Ai, H Ouyang, L Cheng
Experimental & Molecular Medicine, 2021-04-15;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
WLS/wntless is essential in controlling dendritic cell homeostasis via a WNT signaling-independent mechanism
Authors: LT Wang, MH Lin, KY Liu, SS Chiou, SN Wang, CY Chai, LW Tseng, HC Chiou, HC Wang, KK Yokoyama, SH Hsu, SK Huang
Autophagy, 2021-04-14;0(0):1-16.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Fascin inhibitor increases intratumoral dendritic cell activation and anti-cancer immunity
Authors: Y Wang, M Song, M Liu, G Zhang, X Zhang, MO Li, X Ma, JJ Zhang, XY Huang
Cell Reports, 2021-04-06;35(1):108948.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
CD8+ T cells inhibit metastasis and CXCL4 regulates its function
Authors: R Joseph, R Soundarara, S Vasaikar, F Yang, KL Allton, L Tian, P den Hollan, S Isgandarov, M Haemmerle, B Mino, T Zhou, C Shin, M Martinez-P, AA Sahin, J Rodriguez-, J Gelovani, JT Chang, G Acharya, AK Sood, II Wistuba, DL Gibbons, LM Solis, MC Barton, N Varadaraja, JM Rosen, XH Zhang, SA Mani
British Journal of Cancer, 2021-04-01;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Complement-Opsonized Nano-Carriers Are Bound by Dendritic Cells (DC) via Complement Receptor (CR)3, and by B Cell Subpopulations via CR-1/2, and Affect the Activation of DC and B-1 Cells
Authors: M Bednarczyk, C Medina-Mon, FJ Fittler, H Stege, M Roskamp, M Kuske, C Langer, M Vahldieck, E Montermann, I Tubbe, N Röhrig, A Dzionek, S Grabbe, M Bros
International Journal of Molecular Sciences, 2021-03-11;22(6):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
N4BP1 negatively regulates NF-&kappaB by binding and inhibiting NEMO oligomerization
Authors: H Shi, L Sun, Y Wang, A Liu, X Zhan, X Li, M Tang, P Anderton, S Hildebrand, J Quan, S Ludwig, EMY Moresco, B Beutler
Nature Communications, 2021-03-02;12(1):1379.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
The Release Kinetics of Eosinophil Peroxidase and Mitochondrial DNA Is Different in Association with Eosinophil Extracellular Trap Formation
Authors: N Germic, T Fettrelet, D Stojkov, A Hosseini, MP Horn, A Karaulov, D Simon, S Yousefi, HU Simon
Cells, 2021-02-03;10(2):.
Species: Human, Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Stem cell transplantation uncovers TDO-AHR regulation of lung dendritic cells in herpesvirus-induced pathology
Authors: SJ Gurczynski, NL Pereira, SM Hrycaj, C Wilke, RL Zemans, BB Moore
JCI Insight, 2021-01-25;6(2):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
D-mannose ameliorates autoimmune phenotypes in mouse models of lupus
Authors: H Wang, X Teng, G Abboud, W Li, S Ye, L Morel
BMC immunology, 2021-01-05;22(1):1.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Attenuated CSF-1R signalling drives cerebrovascular pathology
Authors: C Delaney, M Farrell, CP Doherty, K Brennan, E O'Keeffe, C Greene, K Byrne, E Kelly, N Birmingham, P Hickey, S Cronin, SN Savvides, SL Doyle, M Campbell
Embo Molecular Medicine, 2020-12-22;0(0):e12889.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture -
The Long Pentraxin 3 (PTX3) Suppresses Immunity to Cutaneous Leishmaniasis by Regulating CD4+ T Helper Cell Response
Authors: G Gupta, Z Mou, P Jia, R Sharma, R Zayats, SM Viana, L Shan, A Barral, VS Boaventura, TT Murooka, A Soussi-Gou, CI de Oliveir, JE Uzonna
Cell Reports, 2020-12-15;33(11):108513.
Species: Transgenic Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Myeloid-derived suppressor cells therapy enhance immunoregulatory properties in acute graft versus host disease with combination of regulatory T cells
Authors: MJ Park, JA Baek, SY Kim, KA Jung, JW Choi, SH Park, SK Kwok, ML Cho
Journal of Translational Medicine, 2020-12-14;18(1):483.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Mechanotransduction via a TRPV4-Rac1 signaling axis plays a role in multinucleated giant cell formation
Authors: RK Arya, R Goswami, SO Rahaman
The Journal of Biological Chemistry, 2020-12-04;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture -
Capping protein regulator and myosin 1 linker 3 regulates transcription of key cytokines in activated phagocytic cells
Authors: N Zhao, W Dong, H Kim, R Moallemian, J Lv, H Wang, H Zheng, F Wei, X Ma
Cell Signal, 2020-11-24;78(0):109848.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture -
Endogenous DEL-1 restrains melanoma lung metastasis by limiting myeloid cell-associated lung inflammation
Authors: YM Hyun, SU Seo, WS Choi, HJ Kwon, DY Kim, S Jeong, GY Kang, E Yi, M Kim, HJ Ryu, MR Looney, EY Choi, HS Kim
Sci Adv, 2020-11-06;6(45):.
Species: Mouse
Sample Types: In Vivo, Whole Cells
Applications: Bioassay, In Vivo -
Differential responses of murine alveolar macrophages to elongate mineral particles of asbestiform and non-asbestiform varieties: Cytotoxicity, cytokine secretion and transcriptional changes
Authors: TO Khaliullin, ER Kisin, S Guppi, N Yanamala, V Zhernovkov, AA Shvedova
Toxicology and Applied Pharmacology, 2020-10-24;409(0):115302.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture -
C9orf72 in myeloid cells suppresses STING-induced inflammation
Authors: ME McCauley, JG O'Rourke, A Yáñez, JL Markman, R Ho, X Wang, S Chen, D Lall, M Jin, AKMG Muhammad, S Bell, J Landeros, V Valencia, M Harms, M Arditi, C Jefferies, RH Baloh
Nature, 2020-08-19;585(7823):96-101.
Species: Mouse, Transgenic Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Sclerostin expression in trabecular bone is downregulated by osteoclasts
Authors: M Koide, T Yamashita, K Murakami, S Uehara, K Nakamura, M Nakamura, M Matsushita, T Ara, H Yasuda, JM Penninger, N Takahashi, N Udagawa, Y Kobayashi
Sci Rep, 2020-08-13;10(1):13751.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay, Cell Culture -
TMEM59 interacts with TREM2 and modulates TREM2-dependent microglial activities
Authors: Z Liu, J Ning, X Zheng, J Meng, L Han, H Zheng, L Zhong, XF Chen, X Zhang, H Luo, D Can, H Xu, YW Zhang
Cell Death Dis, 2020-08-13;11(8):678.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Zinc Finger Protein St18 Protects against Septic Death by Inhibiting VEGF-A from Macrophages
Authors: K Maruyama, H Kidoya, N Takemura, E Sugisawa, O Takeuchi, T Kondo, MMA Eid, H Tanaka, MM Martino, N Takakura, Y Takayama, S Akira, A Vandenbon, Y Kumagai
Cell Rep, 2020-07-14;32(2):107906.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
The pore size of mesoporous silica nanoparticles regulates their antigen delivery efficiency
Authors: X Hong, X Zhong, G Du, Y Hou, Y Zhang, Z Zhang, T Gong, L Zhang, X Sun
Sci Adv, 2020-06-19;6(25):eaaz4462.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
CD11cHi�monocyte-derived macrophages are a major cellular compartment infected by Mycobacterium tuberculosis
Authors: J Lee, S Boyce, J Powers, C Baer, CM Sassetti, SM Behar
PLoS Pathog., 2020-06-16;16(6):e1008621.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
IL-23 in arthritic and inflammatory pain development in mice
Authors: KM Lee, Z Zhang, A Achuthan, AJ Fleetwood, JE Smith, JA Hamilton, AD Cook
Arthritis Res. Ther., 2020-05-29;22(1):123.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo -
Adjuvant activity of Mycobacteria-derived mycolic acids
Authors: M Kubota, E Iizasa, Y Chuuma, H Kiyohara, H Hara, H Yoshida
Heliyon, 2020-05-27;6(5):e04064.
Species: Mouse
Sample Types: Whole Cell
Applications: Bioassay -
Core N-Glycan Structures Are Critical for the Pathogenicity of Cryptococcus neoformans by Modulating Host Cell Death
Authors: EJ Thak, SB Lee, S Xu-Vanpala, DJ Lee, SY Chung, YS Bahn, DB Oh, ML Shinohara, HA Kang
MBio, 2020-05-12;11(3):.
Species: Mouse
Sample Types:
Applications: Cell Culture -
Midkine activation of CD8+ T cells establishes a neuron-immune-cancer axis responsible for low-grade glioma growth
Authors: X Guo, Y Pan, M Xiong, S Sanapala, C Anastasaki, O Cobb, S Dahiya, DH Gutmann
Nat Commun, 2020-05-01;11(1):2177.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture -
Tumor-Intrinsic or Drug-Induced Immunogenicity Dictates the Therapeutic Success of the PD1/PDL Axis Blockade
Authors: A Rossi, V Lucarini, I Macchia, P Sestili, C Buccione, S Donati, M Ciccolella, A Sistigu, MT D'Urso, AM Pacca, E Cardarelli, F Mattei, E Proietti, G Schiavoni, L Bracci
Cells, 2020-04-10;9(4):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Loss of FOXM1 in macrophages promotes pulmonary fibrosis by activating p38 MAPK signaling pathway
Authors: C Goda, D Balli, M Black, D Milewski, T Le, V Ustiyan, X Ren, VV Kalinichen, TV Kalin
PLoS Genet., 2020-04-09;16(4):e1008692.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
MsrA Suppresses Inflammatory Activation of Microglia and Oxidative Stress to Prevent Demyelination via Inhibition of the NOX2-MAPKs/NF-&kappaB Signaling Pathway
Authors: H Fan, D Li, X Guan, Y Yang, J Yan, J Shi, R Ma, Q Shu
Drug Des Devel Ther, 2020-04-05;14(0):1377-1389.
Species: Mouse
Sample Types: Whole Tissue
Applications: Bioassay -
Radiation-induced small extracellular vesicles as "carriages" promote tumor antigen release and trigger antitumor immunity
Authors: W Lin, Y Xu, X Chen, J Liu, Y Weng, Q Zhuang, F Lin, Z Huang, S Wu, J Ding, L Chen, X Qiu, L Zhang, J Wu, D Lin, S Qiu
Theranostics, 2020-03-26;10(11):4871-4884.
Species: Mouse
Sample Types: bone marrow cells
Applications: Cell Culture -
Therapeutic modulation of phagocytosis in glioblastoma can activate both innate and adaptive antitumour immunity
Authors: CA von Roemel, Y Wang, Y Qie, H Yuan, H Zhao, X Liu, Z Yang, M Yang, W Deng, KA Bruno, CK Chan, AS Lee, SS Rosenfeld, K Yun, AJ Johnson, DA Mitchell, W Jiang, BYS Kim
Nat Commun, 2020-03-20;11(1):1508.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture -
I-alowCD11bhigh DC Regulates the Immune Response in the Eyes of Experimental Autoimmune Uveitis
Authors: Y Zhao, J Wang, Z Min, L Peng, S Qi, W Lin
Mediators Inflamm., 2020-03-10;2020(0):6947482.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
ABCA1 Exerts Tumor-Suppressor Function in Myeloproliferative Neoplasms
Authors: M Viaud, O Abdel-Waha, J Gall, S Ivanov, R Guinamard, S Sore, J Merlin, M Ayrault, E Guilbaud, A Jacquel, P Auberger, N Wang, RL Levine, AR Tall, L Yvan-Charv
Cell Rep, 2020-03-10;30(10):3397-3410.e5.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Sirtuin 1 regulates mitochondrial function and immune homeostasis in respiratory syncytial virus infected dendritic cells
Authors: S Elesela, SB Morris, S Narayanan, S Kumar, DB Lombard, NW Lukacs
PLoS Pathog., 2020-02-27;16(2):e1008319.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Adenovirus-Antibody Complexes Contributed to Lethal Systemic Inflammation in a Gene Therapy Trial
Authors: S Somanathan, R Calcedo, JM Wilson
Mol. Ther., 2020-02-07;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture -
Granulocyte-macrophage colony stimulating factor as an indirect mediator of nociceptor activation and pain
Authors: D Tewari, AD Cook, MC Lee, AD Christense, A Croxford, B Becher, D Poole, P Rajasekhar, N Bunnett, JE Smith, JA Hamilton, SB McMahon
J. Neurosci., 2020-02-04;0(0):.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo -
Mechanotransduction via a TRPV4-Rac1 signaling axis plays a role in multinucleated giant cell formation
Authors: RK Arya, R Goswami, SO Rahaman
The Journal of Biological Chemistry, 2020-01-01;296(0):100129.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Antibody blockade of Dectin-2 suppresses house dust mite-induced Th2 cytokine production in dendritic cell- and monocyte-depleted peripheral blood mononuclear cell co-cultures from asthma patients
Authors: MH Chen, MT Huang, WK Yu, SS Lee, JH Wang, TR Cheng, MR Bowman, SL Hsieh
J. Biomed. Sci., 2019-12-20;26(1):97.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture -
Divergent effects of Wnt5b on IL-3- and GM-CSF-induced myeloid differentiation
Authors: MM de Rezende, JP Ng-Blichfe, GZ Justo, EJ Paredes-Ga, R Gosens
Cell. Signal., 2019-12-17;67(0):109507.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Aspirin inhibits RANKL-induced osteoclast differentiation in dendritic cells by suppressing NF-kappaB and NFATc1 activation
Authors: L Wu, Z Luo, Y Liu, L Jia, Y Jiang, J Du, L Guo, Y Bai, Y Liu
Stem Cell Res Ther, 2019-12-05;10(1):375.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
P2Y6 signaling in alveolar macrophages prevents leukotriene-dependent type 2 allergic lung inflammation
Authors: J Nagai, B Balestrier, LB Fanning, T Kyin, H Cirka, J Lin, M Idzko, A Zech, EY Kim, PJ Brennan, JA Boyce
J. Clin. Invest., 2019-12-02;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Antitumor Reactive T-Cell Responses Are Enhanced In Vivo by DAMP Prothymosin Alpha and Its C-Terminal Decapeptide
Authors: AI Birmpilis, CE Karachalio, P Samara, K Ioannou, P Selemenaki, IV Kostopoulo, N Kavrochori, H Kalbacher, E Livaniou, S Haralambou, A Kotsinas, F Farzaneh, IP Trougakos, W Voelter, MA Dimopoulos, A Bamias, O Tsitsiloni
Cancers (Basel), 2019-11-09;11(11):.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo -
Hepatic Stellate Cells Enhance Liver Cancer Progression by Inducing Myeloid-Derived Suppressor Cells through Interleukin-6 Signaling
Authors: CC Hsieh, CH Hung, M Chiang, YC Tsai, JT He
Int J Mol Sci, 2019-10-13;20(20):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Smad7 Controls Immunoregulatory PDL2/1-PD1 Signaling in Intestinal Inflammation and Autoimmunity
Authors: LP Garo, AK Ajay, M Fujiwara, V Beynon, C Kuhn, G Gabriely, S Sadhukan, R Raheja, S Rubino, HL Weiner, G Murugaiyan
Cell Rep, 2019-09-24;28(13):3353-3366.e5.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture -
The Sympathetic Nervous System Mitigates CNS Autoimmunity via β2-Adrenergic Receptor Signaling in Immune Cells
Authors: LP Araujo, JT Maricato, MG Guereschi, MC Takenaka, VM Nascimento, FM de Melo, FJ Quintana, PC Brum, AS Basso
Cell Rep, 2019-09-17;28(12):3120-3130.e5.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture -
Lipocalin-2 (Lcn-2) Attenuates Polymicrobial Sepsis with LPS Preconditioning (LPS Tolerance) in FcGRIIb Deficient Lupus Mice
Authors: T Ondee, J Gillen, P Visitchana, P Somparn, J Issara-Amp, C Dang Phi, W Chancharoe, D Gurusamy, A Nita-Lazar, A Leelahavan
Cells, 2019-09-11;8(9):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Programmed Death-1 Restrains the Germinal Center in Type 1 Diabetes
Authors: T Martinov, LA Swanson, ER Breed, CG Tucker, AJ Dwyer, JK Johnson, JS Mitchell, NL Sahli, JC Wilson, LM Singh, KA Hogquist, JA Spanier, BT Fife
J. Immunol., 2019-07-19;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Dendritic cells and M2 macrophage play an important role in suppression of Th2-mediated inflammation by adipose stem cells-derived extracellular vesicles
Authors: KS Cho, SA Kang, SD Kim, SJ Mun, HS Yu, HJ Roh
Stem Cell Res, 2019-07-12;39(0):101500.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Anti-cervical carcinoma effect of Portulaca oleracea L. polysaccharides by oral administration on intestinal dendritic cells
Authors: R Zhao, X Shao, G Jia, Y Huang, Z Liu, B Song, J Hou
BMC Complement Altern Med, 2019-07-05;19(1):161.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Chemokine-Binding Proteins Encoded by Parapoxvirus of Red Deer of New Zealand Display Evidence of Gene Duplication and Divergence of Ligand Specificity
Authors: S Sharif, N Ueda, Y Nakatani, LM Wise, S Clifton, Z Lateef, AA Mercer, SB Fleming
Front Microbiol, 2019-06-25;10(0):1421.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture -
Differential Uptake of NAGLU-IGF2 and Unmodified NAGLU in Cellular Models of Sanfilippo Syndrome Type B
Authors: H Prill, A Luu, B Yip, J Holtzinger, MJ Lo, TM Christians, G Yogalingam, M Aoyagi-Sch, JH LeBowitz, BE Crawford, R Lawrence
Mol Ther Methods Clin Dev, 2019-05-24;14(0):56-63.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Secreted nuclear protein DEK regulates hematopoiesis through CXCR2 signaling
Authors: ML Capitano, N Mor-Vaknin, AK Saha, S Cooper, M Legendre, H Guo, R Contreras-, F Kappes, MA Sartor, CT Lee, X Huang, DM Markovitz, HE Broxmeyer
J. Clin. Invest., 2019-05-20;130(0):2555-2570.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Ectromelia virus suppresses expression of cathepsins and cystatins in conventional dendritic cells to efficiently execute the replication process
Authors: M Bossowska-, MB Mielcarska, M Romaniewic, MM Kaczmarek, KP Gregorczyk, J Struzik, M Grodzik, MM Giery?ska, FN Toka, L Szulc-D?br
BMC Microbiol., 2019-05-10;19(1):92.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
The Effects of Immunosuppressive Factors on Primary Dendritic Cells from C57BL/6 and CBA Mice
Authors: VV Kurilin, JN Khantakova, VP Tereschenk, JA Lopatnikov, IA Obleukhova, SV Sennikov
J Immunol Res, 2019-04-18;2019(0):7029726.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Homoharringtonine exhibits potent anti-tumor effect and modulates DNA epigenome in acute myeloid leukemia by targeting SP1/TET1/5hmC
Authors: C Li, L Dong, R Su, Y Bi, Y Qing, X Deng, Y Zhou, C Hu, M Yu, H Huang, X Jiang, X Li, X He, D Zou, C Shen, L Han, M Sun, J Skibbe, K Ferchen, X Qin, H Weng, H Huang, C Song, J Chen, J Jin
Haematologica, 2019-04-11;0(0):.
Species: Mouse
Sample Types:
Applications: Bioassay -
Essential Gene Profiles for Human Pluripotent Stem Cells Identify Uncharacterized Genes and Substrate Dependencies
Authors: B Mair, J Tomic, SN Masud, P Tonge, A Weiss, M Usaj, AHY Tong, JJ Kwan, KR Brown, E Titus, M Atkins, KSK Chan, L Munsie, A Habsid, H Han, M Kennedy, B Cohen, G Keller, J Moffat
Cell Rep, 2019-04-09;27(2):599-615.e12.
Species: Human
Sample Types: cell culture
Applications: Differentiation, Differentiation -
Sequential Sensing by TLR2 and Mincle Directs Immature Myeloid Cells to Protect against Invasive Group A Streptococcal Infection in Mice
Authors: T Matsumura, T Ikebe, K Arikawa, M Hosokawa, M Aiko, A Iguchi, I Togashi, S Kai, S Ohara, N Ohara, M Ohnishi, H Watanabe, K Kobayashi, H Takeyama, S Yamasaki, Y Takahashi, M Ato
Cell Rep, 2019-04-09;27(2):561-571.e6.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Siglec-15 as an immune suppressor and potential target for normalization cancer immunotherapy
Authors: J Wang, J Sun, LN Liu, DB Flies, X Nie, M Toki, J Zhang, C Song, M Zarr, X Zhou, X Han, KA Archer, T O'Neill, RS Herbst, AN Boto, MF Sanmamed, S Langermann, DL Rimm, L Chen
Nat. Med., 2019-03-04;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Dampened NLRP3-mediated inflammation in bats and implications for a special viral reservoir host
Authors: M Ahn, DE Anderson, Q Zhang, CW Tan, BL Lim, K Luko, M Wen, WN Chia, S Mani, LC Wang, JHJ Ng, RM Sobota, CA Dutertre, F Ginhoux, ZL Shi, AT Irving, LF Wang
Nat Microbiol, 2019-02-25;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Satb1 regulates the effector program of encephalitogenic tissue Th17 cells in chronic inflammation
Authors: K Yasuda, Y Kitagawa, R Kawakami, Y Isaka, H Watanabe, G Kondoh, T Kohwi-Shig, S Sakaguchi, K Hirota
Nat Commun, 2019-02-01;10(1):549.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Rps14, Csnk1a1 and miRNA145/miRNA146a deficiency cooperate in the clinical phenotype and activation of the innate immune system in the 5q- syndrome
Authors: F Ribezzo, IAM Snoeren, S Ziegler, J Stoelben, PA Olofsen, A Henic, MV Ferreira, S Chen, USA Stalmann, G Buesche, RM Hoogenboez, R Kramann, U Platzbecke, MHGP Raaijmaker, BL Ebert, RK Schneider
Leukemia, 2019-01-16;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Functionalisation of Virus-Like Particles Enhances Antitumour Immune Responses
Authors: K Kramer, F Al-Barwani, MA Baird, VL Young, DS Larsen, VK Ward, SL Young
J Immunol Res, 2019-01-08;2019(0):5364632.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
A microbial-based cancer vaccine for induction of EGFRvIII-specific CD8+ T cells and anti-tumor immunity
Authors: L Zebertavag, S Bambina, J Shugart, A Alice, KD Zens, P Lauer, B Hanson, MJ Gough, MR Crittenden, KS Bahjat
PLoS ONE, 2019-01-02;14(1):e0209153.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization -
MicroRNA Quantitation During Dendritic Cell Endocytosis Using Imaging Flow Cytometry: Key Factors and Requirements
Authors: Q Tong, Y Zhu, D Zhang, Q Cai, W Qu, CDO Cooper, J Wang, PC McHugh
Cell. Physiol. Biochem., 2018-11-21;51(2):793-811.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Consequences of Hypoxia for the Pulmonary Alveolar Epithelial Cell Innate Immune Response
Authors: A Sturrock, D Woller, A Freeman, K Sanders, R Paine
J. Immunol., 2018-10-31;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture -
TLR-stimulated IRAKM activates caspase-8 inflammasome in microglia and promotes neuroinflammation
Authors: CJ Zhang, M Jiang, H Zhou, W Liu, C Wang, Z Kang, B Han, Q Zhang, X Chen, J Xiao, A Fisher, WJ Kaiser, MA Murayama, Y Iwakura, J Gao, J Carman, A Dongre, G Dubyak, DW Abbott, FD Shi, RM Ransohoff, X Li
J. Clin. Invest., 2018-10-29;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Anti-TLR2 antibody triggers oxidative phosphorylation in microglia and increases phagocytosis of ?-amyloid
Authors: A Rubio-Arai, OM Finucane, S Keogh, MA Lynch
J Neuroinflammation, 2018-08-31;15(1):247.
Species: Mouse
Sample Types: Whole Cells
-
Adjuvant effect of the novel TLR1/TLR2 agonist Diprovocim synergizes with anti-PD-L1 to eliminate melanoma in mice
Authors: Y Wang, L Su, MD Morin, BT Jones, Y Mifune, H Shi, KW Wang, X Zhan, A Liu, J Wang, X Li, M Tang, S Ludwig, S Hildebrand, K Zhou, DJ Siegwart, EMY Moresco, H Zhang, DL Boger, B Beutler
Proc. Natl. Acad. Sci. U.S.A., 2018-08-27;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Regulation of T cell afferent lymphatic migration by targeting LT?R-mediated non-classical NF?B signaling
Authors: W Piao, Y Xiong, K Famulski, CC Brinkman, L Li, N Toney, C Wagner, V Saxena, T Simon, JS Bromberg
Nat Commun, 2018-08-01;9(1):3020.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Inflammatory response of microglia to prions is controlled by sialylation of PrPSc
Authors: S Srivastava, E Katorcha, N Makarava, JP Barrett, DJ Loane, IV Baskakov
Sci Rep, 2018-07-27;8(1):11326.
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Administration of cytokine-induced myeloid-derived suppressor cells ameliorates renal fibrosis in diabetic mice
Authors: CC Hsieh, CL Lin, JT He, M Chiang, Y Wang, YC Tsai, CH Hung, PJ Chang
Stem Cell Res Ther, 2018-07-04;9(1):183.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Mutation-specific signaling profiles and kinase inhibitor sensitivities of juvenile myelomonocytic leukemia revealed by induced pluripotent stem cells
Authors: SK Tasian, JA Casas, D Posocco, S Gandre-Bab, AL Gagne, G Liang, ML Loh, MJ Weiss, DL French, ST Chou
Leukemia, 2018-06-08;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Defects in intracellular trafficking of fungal cell wall synthases lead to aberrant host immune recognition
Authors: SK Esher, KS Ost, MA Kohlbrenne, KM Pianalto, CL Telzrow, A Campuzano, CB Nichols, C Munro, FL Wormley, JA Alspaugh
PLoS Pathog., 2018-06-04;14(6):e1007126.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Loss of the Liver X Receptors Disrupts the Balance of Hematopoietic Populations, With Detrimental Effects on Endothelial Progenitor Cells
Authors: A Rasheed, R Tsai, CL Cummins
J Am Heart Assoc, 2018-05-08;7(10):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Increased A20-E3 ubiquitin ligase interactions in bid-deficient glia attenuate TLR3- and TLR4-induced inflammation
Authors: S Kinsella, M Fichtner, O Watters, HG König, JHM Prehn
J Neuroinflammation, 2018-05-02;15(1):130.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Expression of mutant Asxl1 perturbs hematopoiesis and promotes susceptibility to leukemic transformation
Authors: R Nagase, D Inoue, A Pastore, T Fujino, HA Hou, N Yamasaki, S Goyama, M Saika, A Kanai, Y Sera, S Horikawa, Y Ota, S Asada, Y Hayashi, KC Kawabata, R Takeda, HF Tien, H Honda, O Abdel-Waha, T Kitamura
J. Exp. Med., 2018-04-11;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
The oxidized phospholipid oxPAPC protects from septic shock by targeting the non-canonical inflammasome in macrophages
Authors: LH Chu, M Indramohan, RA Ratsimandr, A Gangopadhy, EP Morris, DM Monack, A Dorfleutne, C Stehlik
Nat Commun, 2018-03-08;9(1):996.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
TREM2 Is a Receptor for ?-Amyloid that Mediates Microglial Function
Authors: Y Zhao, X Wu, X Li, LL Jiang, X Gui, Y Liu, Y Sun, B Zhu, JC Piña-Cresp, M Zhang, N Zhang, X Chen, G Bu, Z An, TY Huang, H Xu
Neuron, 2018-03-07;97(5):1023-1031.e7.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Characterization and allergic role of IL-33-induced neutrophil polarization
Authors: B Sun, L Zhu, Y Tao, HX Sun, Y Li, P Wang, Y Hou, Y Zhao, X Zhang, L Zhang, N Na, Y Zhao
Cell. Mol. Immunol., 2018-03-05;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Sphingosine 1-phosphate receptors regulate TLR4-induced CXCL5 release from astrocytes and microglia
Authors: SA O'Sullivan, C O'Sullivan, LM Healy, KK Dev, GK Sheridan
J. Neurochem., 2018-02-21;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
The E3 ubiquitin ligase Triad1 influences development of Mll-Ell-induced acute myeloid leukemia
Authors: H Wang, L Bei, CA Shah, W Huang, LC Platanias, EA Eklund
Oncogene, 2018-02-20;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Activated leukocyte cell adhesion molecule (ALCAM/CD166) regulates T cell responses in a murine model of food allergy
Authors: YS Kim, MN Kim, KE Lee, JY Hong, MS Oh, SY Kim, KW Kim, MH Sohn
Clin. Exp. Immunol., 2018-02-20;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
?M?2Is Antiatherogenic in Female but Not Male Mice
Authors: D Szpak, L Izem, D Verbovetsk, DA Soloviev, VP Yakubenko, E Pluskota
J. Immunol., 2018-02-19;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
The role of HFE genotype in macrophage phenotype
Authors: AM Nixon, E Neely, IA Simpson, JR Connor
J Neuroinflammation, 2018-02-01;15(1):30.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
STING-Dependent Signaling Underlies IL-10 Controlled Inflammatory Colitis
Authors: J Ahn, S Son, SC Oliveira, GN Barber
Cell Rep, 2017-12-26;21(13):3873-3884.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Identification and Characterization of Stimulator of Interferon Genes As a Robust Adjuvant Target for Early Life Immunization
Authors: F Borriello, C Pietrasant, JCY Lai, LM Walsh, P Sharma, DN O'Driscoll, J Ramirez, S Brightman, L Pugni, F Mosca, DJ Burkhart, DJ Dowling, O Levy
Front Immunol, 2017-12-12;8(0):1772.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Systemic administration of ?-glucan of 200�kDa modulates melanoma microenvironment and suppresses metastatic cancer
Authors: M Zhang, L Chun, V Sandoval, H Graor, J Myers, J Nthale, P Rauhe, Z Senders, K Choong, AY Huang, J Kim
Oncoimmunology, 2017-10-30;7(2):e1387347.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture -
Composition of the Schistosoma mansoni worm secretome: Identification of immune modulatory Cyclophilin A
Authors: A Floudas, CD Cluxton, J Fahel, AR Khan, SP Saunders, S Amu, A Alcami, PG Fallon
PLoS Negl Trop Dis, 2017-10-26;11(10):e0006012.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Targeting of Immune Cells by Dual TLR2/7 Ligands Suppresses Features of Allergic Th2 Immune Responses in Mice
Authors: J Laiño, A Wangorsch, F Blanco, S Wolfheimer, M Krause, A Flaczyk, TM Möller, M Tsai, S Galli, S Vieths, M Toda, S Scheurer, S Schülke
J Immunol Res, 2017-10-24;2017(0):7983217.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Glial cells are functionally impaired in juvenile neuronal ceroid lipofuscinosis and detrimental to neurons
Authors: L Parviainen, S Dihanich, GW Anderson, AM Wong, HR Brooks, R Abeti, P Rezaie, G Lalli, S Pope, SJ Heales, HM Mitchison, BP Williams, JD Cooper
Acta Neuropathol Commun, 2017-10-17;5(1):74.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Aminated nanomicelles as a designer vaccine adjuvant to trigger inflammasomes and multiple arms of the innate immune response in lymph nodes
Authors: C Song, H Phuengkham, SY Kim, MS Lee, JH Jeong, SJ Shin, YT Lim
Int J Nanomedicine, 2017-10-12;12(0):7501-7517.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Cysteamine-mediated clearance of antibiotic-resistant pathogens in human cystic fibrosis macrophages
Authors: CL Shrestha, KD Assani, H Rinehardt, F Albastroiu, S Zhang, R Shell, AO Amer, LS Schlesinge, BT Kopp
PLoS ONE, 2017-10-05;12(10):e0186169.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
TREM2 shedding by cleavage at the H157-S158 bond is accelerated for the Alzheimer's disease-associated H157Y variant
Authors: P Thornton, J Sevalle, MJ Deery, G Fraser, Y Zhou, S Ståhl, EH Franssen, RB Dodd, S Qamar, B Gomez Pere, LS Nicol, S Eketjäll, J Revell, C Jones, A Billinton, PH St George-, I Chessell, DC Crowther
EMBO Mol Med, 2017-10-01;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Conjugation of wildtype and hypoallergenic mugwort allergen Art v 1 to flagellin induces IL-10-DC and suppresses allergen-specific TH2-responses in vivo
Authors: S Stefan, K Kirsten, W Sonja, D Nadine, W Andrea, R Andreas, B Peter, P Isabel, G Gabriele, F Fatima, V Stefan, T Masako, S Stephan
Sci Rep, 2017-09-18;7(1):11782.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Hypoxia inducible factor HIF-1 promotes myeloid-derived suppressor cells accumulation through ENTPD2/CD39L1 in hepatocellular carcinoma
Authors: DK Chiu, AP Tse, IM Xu, J Di Cui, RK Lai, LL Li, HY Koh, FH Tsang, LL Wei, CM Wong, IO Ng, CC Wong
Nat Commun, 2017-09-11;8(1):517.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
TREM2 promotes A? phagocytosis by upregulating C/EBP?-dependent CD36 expression in microglia
Authors: SM Kim, BR Mun, SJ Lee, Y Joh, HY Lee, KY Ji, HR Choi, EH Lee, EM Kim, JH Jang, HW Song, I Mook-Jung, WS Choi, HS Kang
Sci Rep, 2017-09-11;7(1):11118.
Species: Mouse
Sample Types: Whole Tissue
Applications: Bioassay -
Dormant 5-lipoxygenase in inflammatory macrophages is triggered by exogenous arachidonic acid
Authors: CA Sorgi, S Zarini, SA Martin, RL Sanchez, RF Scandiuzzi, MA Gijón, C Guijas, N Flamand, RC Murphy, LH Faccioli
Sci Rep, 2017-09-08;7(1):10981.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Detection of immune responses after immunotherapy in glioblastoma using PET and MRI
Authors: JP Antonios, H Soto, RG Everson, DL Moughon, AC Wang, J Orpilla, C Radu, BM Ellingson, JT Lee, T Cloughesy, ME Phelps, J Czernin, LM Liau, RM Prins
Proc. Natl. Acad. Sci. U.S.A., 2017-09-05;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Indian Hedgehog Suppresses a Stromal Cell-Driven Intestinal Immune Response
Authors: BF Westendorp, NVJA Büller, ON Karpus, WA van Dop, J Koster, R Versteeg, PJ Koelink, CY Snel, S Meisner, JJTH Roelofs, A Uhmann, E Ver Loren, J Heijmans, H Hahn, V Muncan, ME Wildenberg, GR van den Br
Cell Mol Gastroenterol Hepatol, 2017-09-05;5(1):67-82.e1.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
The influence of macrophage growth factors on Theiler's Murine Encephalomyelitis Virus (TMEV) infection and activation of macrophages
Authors: KM Schneider, NB Watson, SB Minchenber, PT Massa
Cytokine, 2017-08-09;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Funiculosin variants and phosphorylated derivatives promote innate immune responses via the Toll-like receptor 4/myeloid differentiation factor-2 complex
Authors: N Okamoto, K Mizote, H Honda, A Saeki, Y Watanabe, T Yamaguchi-, R Fukui, N Tanimura, Y Motoi, S Akashi-Tak, T Kato, S Fujishita, T Kimura, U Ohto, T Shimizu, T Hirokawa, K Miyake, K Fukase, Y Fujimoto, Y Nagai, K Takatsu
J. Biol. Chem., 2017-07-28;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
The Development of Steady-State Activation Hubs between Adult LTi ILC3s and Primed Macrophages in Small Intestine
Authors: AK Savage, HE Liang, RM Locksley
J. Immunol., 2017-07-26;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Ischemia/Reperfusion Induces Interferon Stimulated Gene Expression in Microglia
Authors: A McDonough, RV Lee, S Noor, C Lee, T Le, M Iorga, JLH Phillips, S Murphy, T Möller, JR Weinstein
J. Neurosci., 2017-07-26;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Inflammasome and Fas-Mediated IL-1? Contributes to Th17/Th1 Cell Induction in Pathogenic Bacterial Infection In Vivo
Authors: R Uchiyama, S Yonehara, S Taniguchi, S Ishido, KJ Ishii, H Tsutsui
J. Immunol., 2017-07-03;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Therapeutic Effects of Methanol Extract from Euphorbia kansui Radix on Imiquimod-Induced Psoriasis
Authors: SJ Kim, YW Jang, KE Hyung, DK Lee, KH Hyun, SY Park, ES Park, KW Hwang
J Immunol Res, 2017-07-02;2017(0):7052560.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Functional paralysis of GM-CSF-derived bone marrow cells productively infected with ectromelia virus
Authors: L Szulc-D?br, J Struzik, A Ostrowska, M Guzera, FN Toka, M Bossowska-, MM Giery?ska, A Winnicka, Z Nowak, MG Niemia?tow
PLoS ONE, 2017-06-12;12(6):e0179166.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
miR-181a and miR-150 regulate dendritic cell immune inflammatory responses and cardiomyocyte apoptosis via targeting JAK1-STAT1/c-Fos pathway
Authors: J Zhu, K Yao, J Guo, H Shi, L Ma, Q Wang, H Liu, W Gao, A Sun, Y Zou, J Ge
J. Cell. Mol. Med., 2017-06-09;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Colony-stimulating factor 1 receptor blockade inhibits tumor growth by altering the polarization of tumor-associated macrophages in hepatocellular carcinoma
Authors: JY Ao, XD Zhu, ZT Chai, H Cai, YY Zhang, KZ Zhang, LQ Kong, N Zhang, BG Ye, DN Ma, HC Sun
Mol. Cancer Ther., 2017-06-01;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Novel application of localized nanodelivery of anti-IL6 protects organ transplant from ischemia reperfusion injuries
Authors: Z Solhjou, M Uehara, B Bahmani, OH Maarouf, T Ichimura, CR Brooks, W Xu, M Yilmaz, A Elkhal, SG Tullius, I Guleria, M McGrath, R Abdi
Am. J. Transplant, 2017-04-18;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Epigenetic regulator CXXC5 recruits DNA demethylase Tet2 to regulate TLR7/9-elicited IFN response in pDCs
Authors: S Ma, X Wan, Z Deng, L Shi, C Hao, Z Zhou, C Zhou, Y Fang, J Liu, J Yang, X Chen, T Li, A Zang, S Yin, B Li, J Plumas, L Chaperot, X Zhang, G Xu, L Jiang, N Shen, S Xiong, X Gao, Y Zhang, H Xiao
J. Exp. Med., 2017-04-17;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
A heart-brain-kidney network controls adaptation to cardiac stress through tissue macrophage activation
Authors: K Fujiu, M Shibata, Y Nakayama, F Ogata, S Matsumoto, K Noshita, S Iwami, S Nakae, I Komuro, R Nagai, I Manabe
Nat. Med., 2017-04-10;23(5):611-622.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo -
Tumor-Associated Macrophages Suppress the Cytotoxic Activity of Antimitotic Agents
Authors: OC Olson, H Kim, DF Quail, EA Foley, JA Joyce
Cell Rep, 2017-04-04;19(1):101-113.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
VISTA deficiency accelerates the development of fatal murine lupus nephritis
Authors: Sabrina Ceeraz
Arthritis & rheumatology (Hoboken, N.J.), 2017-04-01;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Enhancement of antitumor immunity by combination of anti-CTLA-4 antibody and radioimmunotherapy through the suppression of Tregs
Authors: CH Son, J Bae, HR Lee, K Yang, YS Park
Oncol Lett, 2017-03-28;13(5):3781-3786.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Cancer-derived Circulating MicroRNAs Promote Tumor Angiogenesis by Entering Dendritic Cells to Degrade Highly Complementary MicroRNAs
Authors: J Wang, H Ye, D Zhang, K Cheng, Y Hu, X Yu, L Lu, J Hu, C Zuo, B Qian, Y Yu, S Liu, G Liu, C Mao, S Liu
Theranostics, 2017-03-24;7(6):1407-1421.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
The mTOR signal regulates myeloid-derived suppressor cells differentiation and immunosuppressive function in acute kidney injury
Authors: C Zhang, S Wang, J Li, W Zhang, L Zheng, C Yang, T Zhu, R Rong
Cell Death Dis, 2017-03-23;8(3):e2695.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Receptor Mincle promotes skin allergies and is capable of recognizing cholesterol sulfate
Authors: AV Kostarnoy, PG Gancheva, B Lepenies, AI Tukhvatuli, AS Dzharullae, NB Polyakov, DA Grumov, DA Egorova, AY Kulibin, MA Bobrov, EA Malolina, PA Zykin, AI Soloviev, E Riabenko, DV Maltseva, DA Sakharov, AG Tonevitsky, LV Verkhovska, DY Logunov, BS Naroditsky, AL Gintsburg
Proc. Natl. Acad. Sci. U.S.A, 2017-03-14;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Eosinophils Promote Antiviral Immunity in Mice Infected with Influenza A Virus
Authors: AE Samarasing, RC Melo, S Duan, KS LeMessurie, S Liedmann, SL Surman, JJ Lee, JL Hurwitz, PG Thomas, JA McCullers
J. Immunol, 2017-03-10;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
A Bach2-Cebp Gene Regulatory Network for the Commitment of Multipotent Hematopoietic Progenitors
Authors: A Itoh-Nakad, M Matsumoto, H Kato, J Sasaki, Y Uehara, Y Sato, R Ebina-Shib, M Morooka, R Funayama, K Nakayama, K Ochiai, A Muto, K Igarashi
Cell Rep, 2017-03-07;18(10):2401-2414.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Atg7 Deficiency Intensifies Inflammasome Activation and Pyroptosis in Pseudomonas Sepsis
Authors: Q Pu, C Gan, R Li, Y Li, S Tan, X Li, Y Wei, L Lan, X Deng, H Liang, F Ma, M Wu
J. Immunol, 2017-03-03;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Safe Recombinant Outer Membrane Vesicles that Display M2e Elicit Heterologous Influenza Protection
Authors: HC Watkins, CG Rappazzo, JS Higgins, X Sun, N Brock, A Chau, A Misra, JP Cannizzo, MR King, TR Maines, CA Leifer, GR Whittaker, MP DeLisa, D Putnam
Mol. Ther, 2017-02-16;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Collagen scaffold microenvironments modulate cell lineage commitment for differentiation of bone marrow cells into regulatory dendritic cells
Authors: Y Fang, B Wang, Y Zhao, Z Xiao, J Li, Y Cui, S Han, J Wei, B Chen, J Han, Q Meng, X Hou, J Luo, J Dai, Z Jing
Sci Rep, 2017-02-07;7(0):42049.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Granulocyte-macrophage colony-stimulating factor increases tumor growth and angiogenesis directly by promoting endothelial cell function and indirectly by enhancing the mobilization and recruitment of proangiogenic granulocytes
Authors: Q Zheng, X Li, X Cheng, T Cui, Y Zhuo, W Ma, X Zhao, P Zhao, X Liu, W Feng
Tumour Biol, 2017-02-01;39(2):1010428317692.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo -
Young microglia restore amyloid plaque clearance of aged microglia
Authors: Anna Daria
EMBO J, 2016-12-21;0(0):.
Species: Mouse
Sample Types: Complex Sample Type
Applications: Bioassay -
Ras oncogene-independent activation of RALB signaling is a targetable mechanism of escape from NRAS(V12) oncogene addiction in acute myeloid leukemia
Oncogene, 2016-12-19;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
LRP1 modulates the microglial immune response via regulation of JNK and NF-?B signaling pathways
J Neuroinflammation, 2016-12-08;13(1):304.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Soluble TNF Regulates TACE via AP-2? Transcription Factor in Mouse Dendritic Cells
Authors: L Ge, NL Vujanovic
J. Immunol., 2016-11-16;198(1):417-427.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Roles of endoplasmic reticulum stress-mediated apoptosis in M1-polarized macrophages during mycobacterial infections
Sci Rep, 2016-11-15;6(0):37211.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Macrophages and cardiac fibroblasts are the main producers of eotaxins and regulate eosinophil trafficking to the heart
Eur J Immunol, 2016-10-25;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
M1/M2-macrophage phenotypes regulate renal calcium oxalate crystal development.
Authors: Kazumi Taguchi, Atsushi Okada, Shuzo Hamamoto, Rei Unno, Yoshinobu Moritoki, Ryosuke Ando, Kentaro Mizuno, Keiichi Tozawa, Kenjiro Kohri, Takahiro Yasui
Scientific Reports, 2016-10-12;0(0):2045-2322.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Aripiprazole inhibits polyI:C-induced microglial activation possibly via TRPM7
Schizophr Res, 2016-09-07;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Interferon regulatory factor 4 (IRF4) controls myeloid-derived suppressor cell (MDSC) differentiation and function
J Leukoc Biol, 2016-09-06;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Granulocyte macrophage colony-stimulating factor induces CCL17 production via IRF4 to mediate inflammation
J Clin Invest, 2016-08-15;0(0):.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo -
CD8+ T cells produce a dialyzable antigen-specific activator of dendritic cells
J Leukoc Biol, 2016-08-11;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Liver X receptor and STAT1 cooperate downstream of Gas6/Mer to induce anti-inflammatory arginase 2 expression in macrophages
Sci Rep, 2016-07-13;6(0):29673.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Hepatitis C Virus Stimulates Murine CD8?-Like Dendritic Cells to Produce Type I Interferon in a TRIF-Dependent Manner
PLoS Pathog, 2016-07-06;12(7):e1005736.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
A Human Trypanosome Suppresses CD8+ T Cell Priming by Dendritic Cells through the Induction of Immune Regulatory CD4+ Foxp3+ T Cells
Authors: Jonatan Ersching
PLoS Pathog, 2016-06-22;12(6):e1005698.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Structure of the Plexin Ectodomain Bound by Semaphorin-Mimicking Antibodies
Authors: Kei Suzuki
PLoS ONE, 2016-06-03;11(6):e0156719.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
A Lipid Based Antigen Delivery System Efficiently Facilitates MHC Class-I Antigen Presentation in Dendritic Cells to Stimulate CD8(+) T Cells
Authors: Mithun Maji
Sci Rep, 2016-06-02;6(0):27206.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
A Fusion Protein Consisting of the Vaccine Adjuvant Monophosphoryl Lipid A and the Allergen Ovalbumin Boosts Allergen-Specific Th1, Th2, and Th17 Responses In Vitro
Authors: Stefan Schülke
J Immunol Res, 2016-06-01;2016(0):4156456.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Alpha 1 Antitrypsin Inhibits Dendritic Cell Activation and Attenuates Nephritis in a Mouse Model of Lupus
Authors: Ahmed S Elshikha
PLoS ONE, 2016-05-27;11(5):e0156583.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Bone Marrow CD11c+ Cell-Derived Amphiregulin Promotes Pulmonary Fibrosis
J Immunol, 2016-05-20;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Blockade of Extracellular ATP Effect by Oxidized ATP Effectively Mitigated Induced Mouse Experimental Autoimmune Uveitis (EAU)
PLoS ONE, 2016-05-19;11(5):e0155953.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Dendritic Cell-Like Cells Accumulate in Regenerating Murine Skeletal Muscle after Injury and Boost Adaptive Immune Responses Only upon a Microbial Challenge
PLoS ONE, 2016-05-19;11(5):e0155870.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Powerful Complex Immunoadjuvant Based on Synergistic Effect of Combined TLR4 and NOD2 Activation Significantly Enhances Magnitude of Humoral and Cellular Adaptive Immune Responses
PLoS ONE, 2016-05-17;11(5):e0155650.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Alternatively activated macrophages determine repair of the infarcted adult murine heart
J Clin Invest, 2016-05-03;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
The Combined Deficiency of Immunoproteasome Subunits Affects Both the Magnitude and Quality of Pathogen- and Genetic Vaccination-Induced CD8+ T Cell Responses to the Human Protozoan Parasite Trypanosoma cruzi
PLoS Pathog, 2016-04-29;12(4):e1005593.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
IL-12p40/IL-10 Producing preCD8?/Clec9A+ Dendritic Cells Are Induced in Neonates upon Listeria monocytogenes Infection
Authors: D Torres, A Köhler, S Delbauve, I Caminschi, MH Lahoud, K Shortman, V Flamand
PLoS Pathog, 2016-04-13;12(4):e1005561.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Cutting Edge: CLEC5A Mediates Macrophage Function and Chronic Obstructive Pulmonary Disease Pathologies
Authors: BW Wortham, BL Eppert, JL Flury, SM Garcia, WR Donica, A Osterburg, B Joyce-Shai, DJ Cua, MT Borchers
J. Immunol., 2016-02-29;196(8):3227-31.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS.
Authors: Wang Y, Su L, Morin M, Jones B, Whitby L, Surakattula M, Huang H, Shi H, Choi J, Wang K, Moresco E, Berger M, Zhan X, Zhang H, Boger D, Beutler B
Proc Natl Acad Sci U S A, 2016-02-01;113(7):E884-93.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
The renal microenvironment modifies dendritic cell phenotype.
Authors: Chessa F, Mathow D, Wang S, Hielscher T, Atzberger A, Porubsky S, Gretz N, Burgdorf S, Grone H, Popovic Z
Kidney Int, 2016-01-04;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Antitumor cytotoxicity induced by bone-marrow-derived antigen-presenting cells is facilitated by the tumor suppressor protein p53 via regulation of IL-12
Authors: Tania L Slatter
Oncoimmunology, 2015-12-17;5(3):e1112941.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation.
Authors: Wertz I, Newton K, Seshasayee D, Kusam S, Lam C, Zhang J, Popovych N, Helgason E, Schoeffler A, Jeet S, Ramamoorthi N, Kategaya L, Newman R, Horikawa K, Dugger D, Sandoval W, Mukund S, Zindal A, Martin F, Quan C, Tom J, Fairbrother W, Townsend M, Warming S, DeVoss J, Liu J, Dueber E, Caplazi P, Lee W, Goodnow C, Balazs M, Yu K, Kolumam G, Dixit V
Nature, 2015-12-09;528(7582):370-5.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Protease activity of Per a 10 potentiates Th2 polarization by increasing IL-23 and OX40L.
Authors: Agrawal K, Kale S, Arora N
Eur J Immunol, 2015-10-16;45(12):3375-85.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Identification of the SLAM Adapter Molecule EAT-2 as a Lupus-Susceptibility Gene That Acts through Impaired Negative Regulation of Dendritic Cell Signaling.
Authors: Talaei N, Yu T, Manion K, Bremner R, Wither J
J Immunol, 2015-10-02;195(10):4623-31.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Loss of Phosphatase and Tensin Homolog in APCs Impedes Th17-Mediated Autoimmune Encephalomyelitis.
Authors: Sahin E, Brunner J, Kral J, Kuttke M, Hanzl L, Datler H, Paar H, Neuwinger N, Saferding V, Zinser E, Halfmann A, Soukup K, Hainzl E, Lohmeyer T, Niederreiter B, Haider T, Dohnal A, Kronke G, Bluml S, Schabbauer G
J Immunol, 2015-08-05;195(6):2560-70.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Pneumococal Surface Protein A (PspA) Regulates Programmed Death Ligand 1 Expression on Dendritic Cells in a Toll-Like Receptor 2 and Calcium Dependent Manner.
Authors: Vashishta M, Khan N, Mehto S, Sehgal D, Natarajan K
PLoS ONE, 2015-07-27;10(7):e0133601.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Tumor-Promoting Effects of Myeloid-Derived Suppressor Cells Are Potentiated by Hypoxia-Induced Expression of miR-210.
Authors: Noman M, Janji B, Hu S, Wu J, Martelli F, Bronte V, Chouaib S
Cancer Res, 2015-07-23;75(18):3771-87.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
An A2B Adenosine Receptor Agonist Promotes Th17 Autoimmune Responses in Experimental Autoimmune Uveitis (EAU) via Dendritic Cell Activation.
Authors: Chen M, Liang D, Zuo A, Shao H, Kaplan H, Sun D
PLoS ONE, 2015-07-06;10(7):e0132348.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
RSV-Induced H3K4 Demethylase KDM5B Leads to Regulation of Dendritic Cell-Derived Innate Cytokines and Exacerbates Pathogenesis In Vivo.
Authors: Ptaschinski C, Mukherjee S, Moore M, Albert M, Helin K, Kunkel S, Lukacs N
PLoS Pathog, 2015-06-17;11(6):e1004978.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Angptl4 is upregulated under inflammatory conditions in the bone marrow of mice, expands myeloid progenitors, and accelerates reconstitution of platelets after myelosuppressive therapy.
Authors: Schumacher A, Denecke B, Braunschweig T, Stahlschmidt J, Ziegler S, Brandenburg L, Stope M, Martincuks A, Vogt M, Gortz D, Camporeale A, Poli V, Muller-Newen G, Brummendorf T, Ziegler P
J Hematol Oncol, 2015-06-09;8(0):64.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Granulocyte/Macrophage Colony-stimulating Factor-dependent Dendritic Cells Restrain Lean Adipose Tissue Expansion.
Authors: Pamir N, Liu N, Irwin A, Becker L, Peng Y, Ronsein G, Bornfeldt K, Duffield J, Heinecke J
J Biol Chem, 2015-04-30;290(23):14656-67.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Radiation-driven lipid accumulation and dendritic cell dysfunction in cancer.
Authors: Gao F, Liu C, Guo J, Sun W, Xian L, Bai D, Liu H, Cheng Y, Li B, Cui J, Zhang C, Cai J
Sci Rep, 2015-04-29;5(0):9613.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
HoxA10 Terminates Emergency Granulopoiesis by Increasing Expression of Triad1.
Authors: Wang H, Bei L, Shah C, Hu L, Eklund E
J Immunol, 2015-04-20;194(11):5375-87.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Differential adjuvant activities of TLR7 and TLR9 agonists inversely correlate with nitric oxide and PGE2 production.
Authors: Lee J, Martinez N, West K, Kornfeld H
PLoS ONE, 2015-04-13;10(4):e0123165.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Immunosuppression in early postnatal days induces persistent and allergen-specific immune tolerance to asthma in adult mice.
Authors: Chen, Yan, Zhang, Jin, Lu, Yong, Wang, Libo
PLoS ONE, 2015-04-10;10(4):e0122990.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
mTORC2 Deficiency in Myeloid Dendritic Cells Enhances Their Allogeneic Th1 and Th17 Stimulatory Ability after TLR4 Ligation In Vitro and In Vivo.
Authors: Raich-Regue D, Rosborough B, Watson A, McGeachy M, Turnquist H, Thomson A
J Immunol, 2015-04-03;194(10):4767-76.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
MicroRNA-22 impairs anti-tumor ability of dendritic cells by targeting p38.
Authors: Liang X, Liu Y, Mei S, Zhang M, Xin J, Zhang Y, Yang R
PLoS ONE, 2015-03-31;10(3):e0121510.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Sca-1+Lin-CD117- mesenchymal stem/stromal cells induce the generation of novel IRF8-controlled regulatory dendritic cells through Notch-RBP-J signaling.
Authors: Liu X, Ren S, Ge C, Cheng K, Zenke M, Keating A, Zhao R
J Immunol, 2015-03-30;194(9):4298-308.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Glycogen Synthase Kinase-3beta (GSK-3beta) Inhibition Enhances Dendritic Cell-based Cancer Vaccine Potency via Suppression of Interferon-gamma-induced Indoleamine 2,3-Dioxygenase Expression.
Authors: Noh K, Son K, Jung I, Kang T, Choi C, Park Y
J Biol Chem, 2015-03-26;290(19):12394-402.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Complement receptor C5aR1/CD88 and dipeptidyl peptidase-4/CD26 define distinct hematopoietic lineages of dendritic cells.
Authors: Nakano H, Moran T, Nakano K, Gerrish K, Bortner C, Cook D
J Immunol, 2015-03-13;194(8):3808-19.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Soluble interleukin-15 complexes are generated in vivo by type I interferon dependent and independent pathways.
Authors: Anthony S, Howard M, Hailemichael Y, Overwijk W, Schluns K
PLoS ONE, 2015-03-10;10(3):e0120274.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Hematopoietic stem/progenitor cells express several functional sex hormone receptors-novel evidence for a potential developmental link between hematopoiesis and primordial germ cells.
Authors: Mierzejewska K, Borkowska S, Suszynska E, Suszynska M, Poniewierska-Baran A, Maj M, Pedziwiatr D, Adamiak M, Abdel-Latif A, Kakar S, Ratajczak J, Kucia M, Ratajczak M
Stem Cells Dev, 2015-03-03;24(8):927-37.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
CD41 marks the initial myelo-erythroid lineage specification in adult mouse hematopoiesis: redefinition of murine common myeloid progenitor.
Authors: Miyawaki K, Arinobu Y, Iwasaki H, Kohno K, Tsuzuki H, Iino T, Shima T, Kikushige Y, Takenaka K, Miyamoto T, Akashi K
Stem Cells, 2015-03-01;33(3):976-87.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Cytokine-induced killer cells co-cultured with dendritic cells loaded with the protein lysate produced by radiofrequency ablation induce a specific antitumor response.
Authors: Shan, Chan-Cha, Shi, Liang-Ro, Ding, Mei-Qian, Zhu, Yi-Bei, Li, Xiao-Don, Xu, Bin, Jiang, Jing-Tin, Wu, Chang-Pi
Oncol Lett, 2015-02-17;9(4):1549-1556.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Immune suppressive effects of tonsil-derived mesenchymal stem cells on mouse bone-marrow-derived dendritic cells.
Authors: Park, Minhwa, Kim, Yu-Hee, Ryu, Jung-Hwa, Woo, So-Youn, Ryu, Kyung-Ha
Stem Cells Int, 2015-02-16;2015(0):106540.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Decreased adipogenesis and adipose tissue in mice with inactivated protein phosphatase 5.
Authors: Jacob W, Rosenzweig D, Vazquez-Martin C, Duce S, Cohen P
Biochem J, 2015-02-15;466(0):163-76.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
CXCR4 expression on pathogenic T cells facilitates their bone marrow infiltration in a mouse model of aplastic anemia.
Authors: Arieta Kuksin C, Gonzalez-Perez G, Minter L
Blood, 2015-02-03;125(13):2087-94.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Essential engagement of Toll-like receptor 2 in initiation of early protective Th1 response against rough variants of Mycobacterium abscessus.
Authors: Kim J, Kang M, Kim W, Han S, Kim H, Kim H, Kwon K, Kim S, Cha S, Eum S, Koh W, Cho S, Park J, Shin S
Infect Immun, 2015-02-02;83(4):1556-67.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
High secretion of interferons by human plasmacytoid dendritic cells upon recognition of Middle East respiratory syndrome coronavirus.
Authors: Scheuplein V, Seifried J, Malczyk A, Miller L, Hocker L, Vergara-Alert J, Dolnik O, Zielecki F, Becker B, Spreitzer I, Konig R, Becker S, Waibler Z, Muhlebach M
J Virol, 2015-01-21;89(7):3859-69.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Evasion of innate cytosolic DNA sensing by a gammaherpesvirus facilitates establishment of latent infection.
Authors: Sun C, Schattgen S, Pisitkun P, Jorgensen J, Hilterbrand A, Wang L, West J, Hansen K, Horan K, Jakobsen M, O'Hare P, Adler H, Sun R, Ploegh H, Damania B, Upton J, Fitzgerald K, Paludan S
J Immunol, 2015-01-16;194(4):1819-31.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Neutrophil priming occurs in a sequential manner and can be visualized in living animals by monitoring IL-1beta promoter activation.
Authors: Yao Y, Matsushima H, Ohtola J, Geng S, Lu R, Takashima A
J Immunol, 2014-12-19;194(3):1211-24.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Targeting DNA vaccines to myeloid cells using a small peptide.
Authors: Ye C, Choi J, Abraham S, Shankar P, Manjunath N
Eur J Immunol, 2014-11-02;45(1):82-8.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
The generation of neutrophils in the bone marrow is controlled by autophagy.
Authors: Rozman S, Yousefi S, Oberson K, Kaufmann T, Benarafa C, Simon H
Cell Death Differ, 2014-10-17;22(3):445-56.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
GM-CSF treated F4/80+ BMCs improve murine hind limb ischemia similar to M-CSF differentiated macrophages.
Authors: Kuwahara G, Nishinakamura H, Kojima D, Tashiro T, Kodama S
PLoS ONE, 2014-09-09;9(9):e106987.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
MicroRNA-29b modulates innate and antigen-specific immune responses in mouse models of autoimmunity.
Authors: Salama A, Fichou N, Allard M, Dubreil L, De Beaurepaire L, Viel A, Jegou D, Bosch S, Bach J
PLoS ONE, 2014-09-09;9(9):e106153.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay, Cell Culture -
Maltose-binding protein fusion allows for high level bacterial expression and purification of bioactive mammalian cytokine derivatives.
Authors: Pennati A, Deng J, Galipeau J
PLoS ONE, 2014-09-08;9(9):e106724.
Applications: Western Blot -
Role of TGF-beta signaling in generation of CD39+CD73+ myeloid cells in tumors.
Authors: Ryzhov S, Pickup M, Chytil A, Gorska A, Zhang Q, Owens P, Feoktistov I, Moses H, Novitskiy S
J Immunol, 2014-08-15;193(6):3155-64.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Toll-like receptor 9 mediated responses in cardiac fibroblasts.
Authors: Ohm I, Alfsnes K, Belland Olsen M, Ranheim T, Sandanger O, Dahl T, Aukrust P, Finsen A, Yndestad A, Vinge L
PLoS ONE, 2014-08-15;9(8):e104398.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
A potential protein adjuvant derived from Mycobacterium tuberculosis Rv0652 enhances dendritic cells-based tumor immunotherapy.
Authors: Lee S, Shin S, Lee M, Lee M, Kang T, Park W, Soh B, Park J, Shin Y, Kim H, Yun C, Jung I, Park Y
PLoS ONE, 2014-08-07;9(8):e104351.
Species: Mouse
Sample Types: Whole Cells
Applications: Differentiation, Differentiation -
Macrophage PTEN regulates expression and secretion of arginase I modulating innate and adaptive immune responses.
Authors: Sahin E, Haubenwallner S, Kuttke M, Kollmann I, Halfmann A, Dohnal A, Chen L, Cheng P, Hoesel B, Einwallner E, Brunner J, Kral J, Schrottmaier W, Thell K, Saferding V, Bluml S, Schabbauer G
J Immunol, 2014-07-11;193(4):1717-27.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Endothelial cells translate pathogen signals into G-CSF-driven emergency granulopoiesis.
Authors: Boettcher S, Gerosa R, Radpour R, Bauer J, Ampenberger F, Heikenwalder M, Kopf M, Manz M
Blood, 2014-07-02;124(9):1393-403.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Enhancement of tumor-specific T cell-mediated immunity in dendritic cell-based vaccines by Mycobacterium tuberculosis heat shock protein X.
Authors: Jung I, Shin S, Lee M, Kang T, Han H, Lee S, Kim W, Kim H, Park W, Kim H, Yun C, Lee E, Wu T, Park Y
J Immunol, 2014-07-02;193(3):1233-45.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
DHX15 senses double-stranded RNA in myeloid dendritic cells.
Authors: Lu H, Lu N, Weng L, Yuan B, Liu Y, Zhang Z
J Immunol, 2014-07-02;193(3):1364-72.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Embryonic stem cell-derived haematopoietic progenitor cells down-regulate the CD3 xi chain on T cells, abrogating alloreactive T cells.
Authors: Kim E, Miyake B, Aggarwal M, Voetlause R, Griffith M, Zavazava N
Immunology, 2014-07-01;142(3):421-30.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Cytokine conditioning enhances systemic delivery and therapy of an oncolytic virus.
Authors: Ilett E, Kottke T, Donnelly O, Thompson J, Willmon C, Diaz R, Zaidi S, Coffey M, Selby P, Harrington K, Pandha H, Melcher A, Vile R
Mol Ther, 2014-06-24;22(10):1851-63.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo -
Cardiac fibroblasts mediate IL-17A-driven inflammatory dilated cardiomyopathy.
Authors: Wu L, Ong S, Talor M, Barin J, Baldeviano G, Kass D, Bedja D, Zhang H, Sheikh A, Margolick J, Iwakura Y, Rose N, Cihakova D
J Exp Med, 2014-06-16;211(7):1449-64.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo -
The glycosylated Rv1860 protein of mycobacterium tuberculosis inhibits dendritic cell mediated TH1 and TH17 polarization of T cells and abrogates protective immunity conferred by BCG.
Authors: Satchidanandam V, Kumar N, Jumani R, Challu V, Elangovan S, Khan N
PLoS Pathog, 2014-06-12;10(6):e1004176.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Semapimod sensitizes glioblastoma tumors to ionizing radiation by targeting microglia.
Authors: Miller, Ian S, Didier, Sebastie, Murray, David W, Turner, Tia H, Issaivanan, Magimair, Ruggieri, Rosamari, Al-Abed, Yousef, Symons, Marc
PLoS ONE, 2014-05-09;9(5):e95885.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Adipose tissue macrophages promote myelopoiesis and monocytosis in obesity.
Authors: Nagareddy P, Kraakman M, Masters S, Stirzaker R, Gorman D, Grant R, Dragoljevic D, Hong E, Abdel-Latif A, Smyth S, Choi S, Korner J, Bornfeldt K, Fisher E, Dixit V, Tall A, Goldberg I, Murphy A
Cell Metab, 2014-05-06;19(5):821-35.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
PD-L1 is a novel direct target of HIF-1alpha, and its blockade under hypoxia enhanced MDSC-mediated T cell activation.
Authors: Noman M, Desantis G, Janji B, Hasmim M, Karray S, Dessen P, Bronte V, Chouaib S
J Exp Med, 2014-04-28;211(5):781-90.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Activity of therapeutic JAK 1/2 blockade in graft-versus-host disease.
Authors: Spoerl S, Mathew N, Bscheider M, Schmitt-Graeff A, Chen S, Mueller T, Verbeek M, Fischer J, Otten V, Schmickl M, Maas-Bauer K, Finke J, Peschel C, Duyster J, Poeck H, Zeiser R, von Bubnoff N
Blood, 2014-04-07;123(24):3832-42.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Interleukin-17A modulates circulating tumor cells in tumor draining vein of colorectal cancers and affects metastases.
Authors: Tseng J, Yang C, Liang S, Liu R, Yang S, Lin J, Chen Y, Wu Y, Jiang J, Lin C
Clin Cancer Res, 2014-03-27;20(11):2885-97.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo -
Acanthamoeba protease activity promotes allergic airway inflammation via protease-activated receptor 2.
Authors: Park, Mi Kyung, Cho, Min Kyou, Kang, Shin Ae, Park, Hye-Kyun, Kim, Dong-Hee, Yu, Hak Sun
PLoS ONE, 2014-03-21;9(3):e92726.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Axl receptor blockade ameliorates pulmonary pathology resulting from primary viral infection and viral exacerbation of asthma.
Authors: Shibata T, Habiel D, Coelho A, Kunkel S, Lukacs N, Hogaboam C
J Immunol, 2014-03-21;192(8):3569-81.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
RBP4 activates antigen-presenting cells, leading to adipose tissue inflammation and systemic insulin resistance.
Authors: Moraes-Vieira P, Yore M, Dwyer P, Syed I, Aryal P, Kahn B
Cell Metab, 2014-03-04;19(3):512-26.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Colony-stimulating factor-1 signaling suppresses renal crystal formation.
Authors: Taguchi K, Okada A, Kitamura H, Yasui T, Naiki T, Hamamoto S, Ando R, Mizuno K, Kawai N, Tozawa K, Asano K, Tanaka M, Miyoshi I, Kohri K
J Am Soc Nephrol, 2014-02-27;25(8):1680-97.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Murine experimental autoimmune encephalomyelitis is diminished by treatment with the angiogenesis inhibitors B20-4.1.1 and angiostatin (K1-3).
Authors: MacMillan C, Doucette C, Warford J, Furlong S, Hoskin D, Easton A
PLoS ONE, 2014-02-26;9(2):e89770.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Aging is associated with increased regulatory T-cell function.
Authors: Garg S, Delaney C, Toubai T, Ghosh A, Reddy P, Banerjee R, Yung R
Aging Cell, 2014-02-25;13(3):441-8.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Continuous retinoic acid induces the differentiation of mature regulatory monocytes but fails to induce regulatory dendritic cells.
Authors: VanGundy, Zachary, Guerau-de-Arellano, Mireia, Baker, Julie D, Strange, Heather, Olivo-Marston, Susan, Muth, Dillon C, Papenfuss, Tracey L
BMC Immunol, 2014-02-18;15(0):8.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Tick-borne flaviviruses antagonize both IRF-1 and type I IFN signaling to inhibit dendritic cell function.
Authors: Robertson S, Lubick K, Freedman B, Carmody A, Best S
J Immunol, 2014-02-14;192(6):2744-55.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
MHC class II transactivator is an in vivo regulator of osteoclast differentiation and bone homeostasis co-opted from adaptive immunity.
Authors: Benasciutti E, Mariani E, Oliva L, Scolari M, Perilli E, Barras E, Milan E, Orfanelli U, Fazzalari N, Campana L, Capobianco A, Otten L, Particelli F, Acha-Orbea H, Baruffaldi F, Faccio R, Sitia R, Reith W, Cenci S
J Bone Miner Res, 2014-02-01;29(2):290-303.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
GM-CSF-responsive monocyte-derived dendritic cells are pivotal in Th17 pathogenesis.
Authors: Ko H, Brady J, Ryg-Cornejo V, Hansen D, Vremec D, Shortman K, Zhan Y, Lew A
J Immunol, 2014-01-31;192(5):2202-9.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Characterization of the structure and immunostimulatory activity of a vaccine adjuvant, de-O-acylated lipooligosaccharide.
Authors: Han, Ji Eun, Wui, Seo Ri, Kim, Kwang Su, Cho, Yang Je, Cho, Wan Je, Lee, Na Gyong
PLoS ONE, 2014-01-22;9(1):e85838.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Subcapsular sinus macrophages limit dissemination of West Nile virus particles after inoculation but are not essential for the development of West Nile virus-specific T cell responses.
Authors: Winkelmann E, Widman D, Xia J, Johnson A, Van Rooijen N, Mason P, Bourne N, Milligan G
Virology, 2014-01-10;450(0):278-89.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
RIG-I modulates Src-mediated AKT activation to restrain leukemic stemness.
Authors: Li X, Jiang L, Chen L, Ding M, Guo H, Zhang W, Zhang H, Ma X, Liu X, Xi X, Chen S, Chen Z, Zhu J
Mol Cell, 2014-01-09;53(3):407-19.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
DNA demethylating agent 5-azacytidine inhibits myeloid-derived suppressor cells induced by tumor growth and cyclophosphamide treatment.
Authors: Mikyskova R, Indrova M, Vlkova V, Bieblova J, Simova J, Parackova Z, Pajtasz-Piasecka E, Rossowska J, Reinis M
J Leukoc Biol, 2014-01-03;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Group B Streptococcus engages an inhibitory Siglec through sialic acid mimicry to blunt innate immune and inflammatory responses in vivo.
Authors: Chang Y, Olson J, Beasley F, Tung C, Zhang J, Crocker P, Varki A, Nizet V
PLoS Pathog, 2014-01-02;10(1):e1003846.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Key role of microRNA in the regulation of granulocyte macrophage colony-stimulating factor expression in murine alveolar epithelial cells during oxidative stress.
Authors: Sturrock, Anne, Mir-Kasimov, Mustafa, Baker, Jessica, Rowley, Jesse, Paine, Robert 3
J Biol Chem, 2013-12-26;289(7):4095-105.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Borrelia burgdorferi elicited-IL-10 suppresses the production of inflammatory mediators, phagocytosis, and expression of co-stimulatory receptors by murine macrophages and/or dendritic cells.
Authors: Chung Y, Zhang N, Wooten R
PLoS ONE, 2013-12-19;8(12):e84980.
Species: Mouse
Sample Types: Whole Tissue
Applications: Bioassay -
Aged mice are unable to mount an effective myeloid response to sepsis.
Authors: Nacionales D, Gentile L, Vanzant E, Lopez M, Cuenca A, Cuenca A, Ungaro R, Li Y, Baslanti T, Bihorac A, Moore F, Baker H, Leeuwenburgh C, Moldawer L, Efron P
J Immunol, 2013-12-13;192(2):612-22.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Therapeutic efficacy of suppressing the Jak/STAT pathway in multiple models of experimental autoimmune encephalomyelitis.
Authors: Liu Y, Holdbrooks A, De Sarno P, Rowse A, Yanagisawa L, McFarland B, Harrington L, Raman C, Sabbaj S, Benveniste E, Qin H
J Immunol, 2013-12-09;192(1):59-72.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
TRAF5 negatively regulates TLR signaling in B lymphocytes.
Authors: Buchta C, Bishop G
J Immunol, 2013-11-20;192(1):145-50.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Preclinical to clinical translation of tofacitinib, a Janus kinase inhibitor, in rheumatoid arthritis.
Authors: Dowty, Martin E, Jesson, Michael, Ghosh, Sarbani, Lee, Jamie, Meyer, Debra M, Krishnaswami, Sriram, Kishore, Nandini
J Pharmacol Exp Ther, 2013-11-11;348(1):165-73.
Species: Mouse
Sample Types: Whole Blood
Applications: Bioassay -
The leukemia-associated Mll-Ell oncoprotein induces fibroblast growth factor 2 (Fgf2)-dependent cytokine hypersensitivity in myeloid progenitor cells.
Authors: Shah, Chirag A, Bei, Ling, Wang, Hao, Platanias, Leonidas, Eklund, Elizabet
J Biol Chem, 2013-10-02;288(45):32490-505.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Mycobacterium tuberculosis RpfB drives Th1-type T cell immunity via a TLR4-dependent activation of dendritic cells.
Authors: Kim J, Kim W, Choi H, Jang B, Lee K, Park J, Kim H, Cho S, Shin S
J Leukoc Biol, 2013-07-03;94(4):733-49.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Identification, characterization, and isolation of a common progenitor for osteoclasts, macrophages, and dendritic cells from murine bone marrow and periphery.
Authors: Jacome-Galarza C, Lee S, Lorenzo J, Aguila H
J Bone Miner Res, 2013-05-01;28(5):1203-13.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
PGI(2) signaling inhibits antigen uptake and increases migration of immature dendritic cells.
Authors: Toki S, Goleniewska K, Huckabee M, Zhou W, Newcomb D, FitzGerald G, Lawson W, Peebles R
J Leukoc Biol, 2013-04-26;94(1):77-88.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Inefficient TLR4/MD-2 heterotetramerization by monophosphoryl lipid A.
Authors: Casella C, Mitchell T
PLoS ONE, 2013-04-26;8(4):e62622.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Prostate cancer stem cells are targets of both innate and adaptive immunity and elicit tumor-specific immune responses.
Authors: Jachetti, Elena, Mazzoleni, Stefania, Grioni, Matteo, Ricupito, Alessia, Brambillasca, Chiara, Generoso, Luca, Calcinotto, Arianna, Freschi, Massimo, Mondino, Anna, Galli, Rossella, Bellone, Matteo
Oncoimmunology, 2013-04-16;2(5):e24520.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Deletion of CD74, a putative MIF receptor, in mice enhances osteoclastogenesis and decreases bone mass.
Authors: Mun S, Won H, Hernandez P, Aguila H, Lee S
J Bone Miner Res, 2013-04-01;28(4):948-59.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Differential requirements of CD4(+) T-cell signals for effector cytotoxic T-lymphocyte (CTL) priming and functional memory CTL development at higher CD8(+) T-cell precursor frequency.
Authors: Umeshappa C, Nanjundappa R, Xie Y, Freywald A, Xu Q, Xiang J
Immunology, 2013-04-01;138(4):298-306.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Tetraspanin CD37 contributes to the initiation of cellular immunity by promoting dendritic cell migration.
Authors: Gartlan K, Wee J, Demaria M, Nastovska R, Chang T, Jones E, Apostolopoulos V, Pietersz G, Hickey M, van Spriel A, Wright M
Eur J Immunol, 2013-03-25;43(5):1208-19.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
NADPH oxidase limits lipopolysaccharide-induced lung inflammation and injury in mice through reduction-oxidation regulation of NF-kappaB activity.
Authors: Han W, Li H, Cai J, Gleaves L, Polosukhin V, Segal B, Yull F, Blackwell T
J Immunol, 2013-03-25;190(9):4786-94.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Emulsified phosphatidylserine, simple and effective peptide carrier for induction of potent epitope-specific T cell responses.
Authors: Ichihashi, Toru, Satoh, Toshifum, Sugimoto, Chihiro, Kajino, Kiichi
PLoS ONE, 2013-03-22;8(3):e60068.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Dectin-1 regulates IL-10 production via a MSK1/2 and CREB dependent pathway and promotes the induction of regulatory macrophage markers.
Authors: Elcombe S, Naqvi S, van den Bosch M, Mackenzie K, Cianfanelli F, Brown G, Arthur J
PLoS ONE, 2013-03-22;8(3):e60086.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Fas-associated phosphatase 1 (Fap1) influences betacatenin activity in myeloid progenitor cells expressing the Bcr-abl oncogene.
Authors: Huang W, Bei L, Eklund E
J Biol Chem, 2013-03-21;288(18):12766-76.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
GSK3beta regulates physiological migration of stem/progenitor cells via cytoskeletal rearrangement.
Authors: Lapid K, Itkin T, D'Uva G, Ovadya Y, Ludin A, Caglio G, Kalinkovich A, Golan K, Porat Z, Zollo M, Lapidot T
J Clin Invest, 2013-03-08;123(4):1705-17.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
TLR2 deletion promotes arthritis through reduction of IL-10.
Authors: Huang Q, Koessler R, Birkett R, Perlman H, Xing L, Pope R
J Leukoc Biol, 2013-02-27;93(5):751-9.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Functional education of invariant NKT cells by dendritic cell tuning of SHP-1.
Authors: Napolitano, Anna, Pittoni, Paola, Beaudoin, Lucie, Lehuen, Agnes, Voehringer, David, MacDonald, H Robson, Dellabona, Paolo, Casorati, Giulia
J Immunol, 2013-02-20;190(7):3299-308.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Radiation-induced loss of cell surface CD47 enhances immune-mediated clearance of human papillomavirus-positive cancer.
Authors: Vermeer D, Spanos W, Vermeer P, Bruns A, Lee K, Lee J
Int J Cancer, 2013-02-12;133(1):120-9.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Inflammasome adaptor protein Apoptosis-associated speck-like protein containing CARD (ASC) is critical for the immune response and survival in west Nile virus encephalitis.
Authors: Kumar M, Roe K, Orillo B, Muruve D, Nerurkar V, Gale M, Verma S
J Virol, 2013-01-09;87(7):3655-67.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Respiratory syncytial virus infection modifies and accelerates pulmonary disease via DC activation and migration.
Authors: Jang, Sihyug, Smit, Joost, Kallal, Lara E, Lukacs, Nicholas
J Leukoc Biol, 2013-01-04;94(1):5-15.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Breast regression protein-39 (BRP-39) promotes dendritic cell maturation in vitro and enhances Th2 inflammation in murine model of asthma.
Authors: Xu Q, Chai S, Qian Y, Zhang M, Wang K
Acta Pharmacol Sin, 2012-11-26;33(12):1525-32.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture -
Inflammatory arthritis increases mouse osteoclast precursors with myeloid suppressor function.
Authors: Charles, Julia F, Hsu, Lih-Yun, Niemi, Erene C, Weiss, Arthur, Aliprantis, Antonios, Nakamura, Mary C
J Clin Invest, 2012-11-01;122(12):4592-605.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
The MSHA Strain of Pseudomonas Aeruginosa Activated TLR Pathway and Enhanced HIV-1 DNA Vaccine Immunoreactivity.
Authors: Hou J, Liu Y, Liu Y, Shao Y
PLoS ONE, 2012-10-15;7(10):e47724.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Dendritic cell exosomes directly kill tumor cells and activate natural killer cells via TNF superfamily ligands.
Authors: Munich S, Sobo-Vujanovic A, Buchser W, Beer-Stolz D, Vujanovic N
Oncoimmunology, 2012-10-01;1(7):1074-1083.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Intravaginal TLR agonists increase local vaccine-specific CD8 T cells and human papillomavirus-associated genital-tumor regression in mice.
Authors: Domingos-Pereira S, Decrausaz L, Derre L, Bobst M, Romero P, Schiller J, Jichlinski P, Nardelli-Haefliger D
Mucosal Immunol, 2012-09-12;6(2):393-404.
Species: Mouse
Sample Types: Tissue Homogenates
Applications: Bioassay -
Regulation of innate CD8+ T-cell activation mediated by cytokines.
Proc Natl Acad Sci U S A, 2012-06-04;109(25):9971-6.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Protein kinase C delta (PKCdelta)-extracellular signal-regulated kinase 1/2 (ERK1/2) signaling cascade regulates glycogen synthase kinase-3 (GSK-3) inhibition-mediated interleukin-10 (IL-10) expression in lipopolysaccharide (LPS)-induced endotoxemia.
Authors: Noh KT, Son KH, Jung ID, Kang HK, Hwang SA, Lee WS, You JC, Park YM
J. Biol. Chem., 2012-03-05;287(17):14226-33.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Macrophages participate in IL-17-mediated inflammation.
Authors: Barin JG, Baldeviano GC, Talor MV, Wu L, Ong S, Quader F, Chen P, Zheng D, Caturegli P, Rose NR, Cihakova D
Eur. J. Immunol., 2012-01-23;42(3):726-36.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Dysregulation in Retinal Para-Inflammation and Age-Related Retinal Degeneration in CCL2 or CCR2 Deficient Mice.
Authors: Chen M, Forrester JV, Xu H
PLoS ONE, 2011-08-05;6(8):e22818.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Neurexophilin 1 suppresses the proliferation of hematopoietic progenitor cells.
Authors: Kinzfogl J, Hangoc G, Broxmeyer HE
Blood, 2011-05-31;118(3):565-75.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Smad1 signaling restricts hematopoietic potential after promoting hemangioblast commitment.
Authors: Cook BD, Liu S, Evans T
Blood, 2011-04-22;117(24):6489-97.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
CCL20/CCR6 blockade enhances immunity to RSV by impairing recruitment of DC.
Authors: Kallal LE, Schaller MA, Lindell DM, Lira SA, Lukacs NW
Eur. J. Immunol., 2010-04-01;40(4):1042-52.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Oncostatin M induces dendritic cell maturation and Th1 polarization.
Authors: Jung ID, Noh KT, Lee CM, Chun SH, Jeong SK, Park JW, Park WS, Kim HW, Yun CH, Shin YK, Park YM
Biochem. Biophys. Res. Commun., 2010-03-04;394(2):272-8.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture -
Unc93B1 biases Toll-like receptor responses to nucleic acid in dendritic cells toward DNA- but against RNA-sensing.
Authors: Fukui R, Saitoh S, Matsumoto F, Kozuka-Hata H, Oyama M, Tabeta K, Beutler B, Miyake K
J. Exp. Med., 2009-05-18;206(6):1339-50.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
The adaptor protein CIKS/Act1 is essential for IL-25-mediated allergic airway inflammation.
Authors: Claudio E, Sonder SU, Saret S, Carvalho G, Ramalingam TR, Wynn TA, Chariot A, Garcia-Perganeda A, Leonardi A, Paun A, Chen A, Ren NY, Wang H, Siebenlist U
J. Immunol., 2009-02-01;182(3):1617-30.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Critical roles of inflammation and apoptosis in improved survival in a model of hyperoxia-induced acute lung injury in Pneumocystis murina-infected mice.
Authors: Beck JM, Preston AM, Wilcoxen SE, Morris SB, Sturrock A, Paine R
Infect. Immun., 2009-01-05;77(3):1053-60.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo -
p47phox deficiency induces macrophage dysfunction resulting in progressive crystalline macrophage pneumonia.
Authors: Liu Q, Cheng LI, Yi L, Zhu N, Wood A, Changpriroa CM, Ward JM, Jackson SH
Am. J. Pathol., 2008-12-18;174(1):153-63.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Adenosine receptors in regulation of dendritic cell differentiation and function.
Authors: Novitskiy SV, Ryzhov S, Zaynagetdinov R, Goldstein AE, Huang Y, Tikhomirov OY, Blackburn MR, Biaggioni I, Carbone DP, Feoktistov I, Dikov MM
Blood, 2008-06-17;112(5):1822-31.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
The type I IFN induction pathway constrains Th17-mediated autoimmune inflammation in mice.
Authors: Guo B, Chang EY, Cheng G
J. Clin. Invest., 2008-05-01;118(5):1680-90.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Lipopolysaccharide-activated IL-10-secreting dendritic cells suppress experimental autoimmune uveoretinitis by MHCII-dependent activation of CD62L-expressing regulatory T cells.
Authors: Lau AW, Biester S, Cornall RJ, Forrester JV
J. Immunol., 2008-03-15;180(6):3889-99.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Bv8 regulates myeloid-cell-dependent tumour angiogenesis.
Authors: Shojaei F, Wu X, Zhong C, Yu L, Liang XH, Yao J, Blanchard D, Bais C, Peale FV, van Bruggen N, Ho C, Ross J, Tan M, Carano RA, Meng YG, Ferrara N
Nature, 2007-12-06;450(7171):825-31.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
B7-DC induced by IL-13 works as a feedback regulator in the effector phase of allergic asthma.
Authors: Matsumoto K, Fukuyama S, Eguchi-Tsuda M, Nakano T, Matsumoto T, Matsumura M, Moriwaki A, Kan-o K, Wada Y, Yagita H, Shin T, Pardoll DM, Patcharee R, Azuma M, Nakanishi Y, Inoue H
Biochem. Biophys. Res. Commun., 2007-11-05;365(1):170-5.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
The endothelial cell-produced antiangiogenic cytokine vascular endothelial growth inhibitor induces dendritic cell maturation.
Authors: Tian F, Grimaldo S, Fujita M, Fugita M, Cutts J, Vujanovic NL, Li LY
J. Immunol., 2007-09-15;179(6):3742-51.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Granulocyte-macrophage colony-stimulating factor prevents diabetes development in NOD mice by inducing tolerogenic dendritic cells that sustain the suppressive function of CD4+CD25+ regulatory T cells.
Authors: Gaudreau S, Guindi C, Menard M, Besin G, Dupuis G, Amrani A
J. Immunol., 2007-09-15;179(6):3638-47.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Angiostatin inhibits monocyte/macrophage migration via disruption of actin cytoskeleton.
Authors: Perri SR, Annabi B, Galipeau J
FASEB J., 2007-07-10;21(14):3928-36.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Nod1-mediated innate immune recognition of peptidoglycan contributes to the onset of adaptive immunity.
Authors: Fritz JH, Le Bourhis L, Sellge G, Magalhaes JG, Fsihi H, Kufer TA, Collins C, Viala J, Ferrero RL, Girardin SE, Philpott DJ
Immunity, 2007-04-12;26(4):445-59.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Lentiviral vector-mediated autonomous differentiation of mouse bone marrow cells into immunologically potent dendritic cell vaccines.
Authors: Koya RC, Kimura T, Ribas A, Rozengurt N, Lawson GW, Faure-Kumar E, Wang HJ, Herschman H, Kasahara N, Stripecke R
Mol. Ther., 2007-03-20;15(5):971-80.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Differing effects of clarithromycin and azithromycin on cytokine production by murine dendritic cells.
Authors: Sugiyama K, Shirai R, Mukae H, Ishimoto H, Nagata T, Sakamoto N, Ishii H, Nakayama S, Yanagihara K, Mizuta Y, Kohno S
Clin. Exp. Immunol., 2007-03-01;147(3):540-6.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Inactivated Sendai virus particles eradicate tumors by inducing immune responses through blocking regulatory T cells.
Authors: Kurooka M, Kaneda Y
Cancer Res., 2007-01-01;67(1):227-36.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
A GMCSF and IL-15 fusokine leads to paradoxical immunosuppression in vivo via asymmetrical JAK/STAT signaling through the IL-15 receptor complex.
Authors: Rafei M, Wu JH, Annabi B, Lejeune L, Francois M, Galipeau J
Blood, 2006-11-02;109(5):2234-42.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Bone marrow-derived cells require a functional glucose 6-phosphate transporter for normal myeloid functions.
Authors: Kim SY, Nguyen AD, Gao JL, Murphy PM, Mansfield BC, Chou JY
J. Biol. Chem., 2006-08-04;281(39):28794-801.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Immunosuppressant triptolide inhibits dendritic cell-mediated chemoattraction of neutrophils and T cells through inhibiting Stat3 phosphorylation and NF-kappaB activation.
Authors: Liu Q, Chen T, Chen G, Li N, Wang J, Ma P, Cao X
Biochem. Biophys. Res. Commun., 2006-05-12;345(3):1122-30.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
GM-CSF action in the CNS decreases food intake and body weight.
Authors: Reed JA, Clegg DJ, Smith KB, Tolod-Richer EG, Matter EK, Picard LS, Seeley RJ
J. Clin. Invest., 2005-11-01;115(11):3035-44.
Species: Rat
Sample Types: In Vivo
Applications: In Vivo -
Vaccination of apoptotic Fas ligand-expressing tumors decreased antitumor responses by enhanced production of immunosuppressive cytokines.
Authors: Wada A, Tada Y, Shimozato O, Takiguchi Y, Tatsumi K, Kuriyama T, Tagawa M
Anticancer Res., 2005-01-01;25(1):299-303.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Differential roles of vascular endothelial growth factor receptors 1 and 2 in dendritic cell differentiation.
Authors: Dikov MM, Ohm JE, Ray N, Tchekneva EE, Burlison J, Moghanaki D, Nadaf S, Carbone DP
J. Immunol., 2005-01-01;174(1):215-22.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
NK cell activation by dendritic cells (DCs) requires the formation of a synapse leading to IL-12 polarization in DCs.
Authors: Borg C, Jalil A, Laderach D, Maruyama K, Wakasugi H, Charrier S, Ryffel B, Cambi A, Figdor C, Vainchenker W, Galy A, Caignard A, Zitvogel L
Blood, 2004-07-08;104(10):3267-75.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Robust conversion of marrow cells to skeletal muscle with formation of marrow-derived muscle cell colonies: a multifactorial process.
Authors: Abedi M, Greer DA, Colvin GA, Demers DA, Dooner MS, Harpel JA, Weier HU, Lambert JF, Quesenberry PJ
Exp. Hematol., 2004-05-01;32(5):426-34.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo -
Dendritic cells phagocytose and are activated by Treponema pallidum.
Authors: Bouis DA, Popova TG, Takashima A, Norgard MV
Infect. Immun., 2001-01-01;69(1):518-28.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Antibodies to vascular endothelial growth factor enhance the efficacy of cancer immunotherapy by improving endogenous dendritic cell function.
Authors: Gabrilovich DI, 2018, Ishida T, Nadaf S, Ohm JE, Carbone DP
1537, 1999-10-01;5(10):2963-70.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Stem cell factor improves the repopulating ability of primitive hematopoietic stem cells after sublethal irradiation (and, to a lesser extent) after bone marrow transplantation in mice.
Authors: Gardner RV, 48657, Oliver P, Astle CM
Involvement of ?-defensin 130 (DEFB130) in the macrophage microbicidal mechanisms for killing Plasmodium falciparum, 1998-01-01;16(2):112-9.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo -
Interleukin-6 and the granulocyte colony-stimulating factor receptor are major independent regulators of granulopoiesis in vivo but are not required for lineage commitment or terminal differentiation.
Authors: Liu F, Poursine-Laurent J, Wu HY, Link DC
Blood, 1997-10-01;90(7):2583-90.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay
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Average Rating: 4.5 (Based on 13 Reviews)
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Reason for Rating: Recombinant mouse GM-CSF was used as a positive control.
Reason for Rating: use this product on a weekly basis for my BMDC experiments. Works consistently and cells looks great.
Reason for Rating: The mouse GM-CSF constantly work good for the experiments. The product is reliable and with high quality.