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Ropinirole

Catalog #: 3680
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3680/50
Ropinirole | CAS No. 91374-20-8 | Non-selective Dopamine Receptor Agonists
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Description: Selective D2-like agonist

Chemical Name: 4-[2-(Dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-one hydrochloride

Purity: ≥99%

Product Details
Citations (1)
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Biological Activity

Ropinirole is a selective D2-like receptor agonist (D3 > D2 > D4). Causes biphasic spontaneous locomotor activity and contralateral circling in 6-OHDA-lesioned mice. Displays anti-Parkinsonian activity.

Technical Data

M.Wt:
296.84
Formula:
C16H24N2O.HCl
Solubility:
Soluble to 100 mM in water and to 50 mM in DMSO
Purity:
≥99%
Storage:
Desiccate at RT
CAS No:
91374-20-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Other Product-Specific Information:

Background References

  1. Pharmacologic profile of ropinirole: a nonergoline DA agonist.
    Tulloch
    Neurology, 1997;49:S58
  2. Preclinical pharmacology of ropin. (SK&F 101468-A) a novel DA D2 agonist.
    Eden et al.
    Pharmacol.Biochem.Behav., 1991;38:147

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Citation for Ropinirole

The citations listed below are publications that use Tocris products. Selected citations for Ropinirole include:

1 Citation: Showing 1 - 1

  1. New phosphosite-specific antibodies to unravel the role of GRK phosphorylation in dopamine D2 receptor regulation and signaling.
    Authors: Stefan Et al.
    Sci Rep  2021;11:8288

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