Simple Plex Control for Human CD21

Catalog #: 898282 Datasheet / COA / SDS

Control for use with Human CD21 Simple Plex Cartridge Kit

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898282

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Simple Plex Control for Human CD21 Summary

INTENDED USE AND DESCRIPTION: For use a quantitative control for the determination of human CD21 concentrations in biological fluids. Controls are supplied lyophilized. Please refer to the lot specific certificate of analysis and Simple Plex Lyophilized Quality Control product insert for additional information.

Specifications

Storage

• Store lyophilized controls at 2-8 °C. Lyophilized controls are stable for up to 12 months from date of receipt.
• Reconstituted controls are stable for up to 6 months from date of preparation when stored at ≤ -70 °C. Storage at -20° C is not recommended.
• Individual frozen aliquots of low and high controls are designed as single-use entities. Thaw directly before use and discard any remaining volume.

Species

Human

Product Datasheets

Product Datasheet

Background: CD21

CD21, also known as complement receptor 2 (CR2), is a 145 kDa transmembrane protein that contains 15 tandem SCR/SUSHI repeats. CD21 is primarily expressed on B cells, follicular dendritic cells, and T cells. It binds the complement component fragments iC3b, C3d, and C3d,g and forms complexes with CD19 and CD35. CD21 is required for germinal center development, antibody production, and B cell tolerance. It also functions as a cellular uptake receptor for Epstein-Barr virus.

Entrez Gene IDs

1380 (Human); 12902 (Mouse); 289395 (Rat)

Alternate Names

C3DR; C3DRSLEB9; CD21 antigen; CD21; Complement C3d receptor; complement component (3d/Epstein Barr virus) receptor 2; complement receptor type 2; CR2; EBV receptor; Epstein-Barr virus receptor