SNAP 94847 hydrochloride

Catalog # Availability Size / Price Qty
3347/10
3347/50
SNAP 94847 hydrochloride | CAS No. 1781934-47-1 | Melanin-concentrating Hormone Receptor Antagonists
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Description: Potent and selective MCH1 antagonist

Chemical Name: N-[3-[1-[[4-(3,4-Difluorophenoxy)phenyl]methyl]-4-piperidinyl]-4-methylphenyl]-2-methylpropanamide hydrochloride

Purity: ≥98%

Product Details
Citations (1)
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Biological Activity

SNAP 94847 hydrochloride is a potent melanin-concentrating hormone receptor 1 (MCH1) antagonist (Ki = 2.2 nM, KD = 530 pM) that displays > 80-fold and > 500-fold selectivity over α1A and D2 receptors respectively. Increases neurogenesis in the dentate gyrus and decreases food-reinforced operant responding in vivo. Exhibits anxiolytic activity and is orally active.

Technical Data

M.Wt:
515.03
Formula:
C29H32F2N2O2.HCl
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
≥98%
Storage:
Desiccate at RT
CAS No:
1781934-47-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citation for SNAP 94847 hydrochloride

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