Tamoxifen

Catalog #: 6342
8 Citations Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
6342/100

Tamoxifen | CAS No. 10540-29-1 | Estrogen and Related Receptor Modulators

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Description: Estrogen receptor partial agonist/antagonist

Chemical Name: 2-[4-[(1Z)-1,2-Diphenyl-1-buten-1-yl]phenoxy]-N,N-dimethylethanamine

Purity: ≥98%

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Product Details

Citations (8)

Reviews

Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

Tamoxifen is a selective estrogen receptor modulator (SERM). Exhibits antiestrogenic effects in mammary tissue and estrogen-like effects in bone. Anticancer. Tamoxifen citrate (Cat.No. 0999) is also available.

Technical Data

M.Wt:

371.51

Formula:

C₂₆H₂₉NO

Solubility:

Soluble to 100 mM in ethanol and to 20 mM in DMSO

Purity:

≥98%

Storage:

Store at +4°C

CAS No:

10540-29-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

Tamoxifen: a most unlikely pioneering medicine.
Jordan et al.
Nat.Rev.Drug Discov., 2003;2:203

Product Datasheets

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⚠ WARNING: This product can expose you to chemicals including Tamoxifen and its salts, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov

Citations for Tamoxifen

The citations listed below are publications that use Tocris products. Selected citations for Tamoxifen include:

8 Citations: Showing 1 - 8

Metabotropic glutamate receptor 5-mediated inhibition of inward-rectifying K+ channel 4.1 contributes to orofacial ectopic mechanical allodynia following inferior alveolar nerve transection in male mice.
Authors: Ya-Jing Et al.
J Neurosci Res 2023;101:1170-1187
ARID1A influences HDAC1/BRD4 activity, intrinsic proliferative capacity and breast cancer treatment response.
Authors: Rachael Et al.
Nat Genet 2020;52:187-197
A homogeneous bioluminescent immunoassay to probe cellular signaling pathway regulation.
Authors: Laurie Et al.
Commun Biol 2020;3:8
Metabolic Imaging Detects Resistance to PI3Kα Inhibition Mediated by Persistent FOXM1 Expression in ER+ Breast Cancer.
Authors: Susana Et al.
Cancer Cell 2020;38:516-533.e9
Study of the Combination of Self-Activating Photodynamic Therapy and Chemotherapy for Cancer Treatment.
Authors: Silva Et al.
Biomolecules 2019;9
Rapid Plasticity of Higher-Order Thalamocortical Inputs during Sensory Learning.
Authors: Alison L Et al.
Neuron 2019;103:277-291.e4
Selective Estrogen Receptor Modulators: Cannabinoid Receptor Inverse Agonists with Differential CB1 and CB2 Selectivity.
Authors: Paul L Et al.
Front Pharmacol 2017;7:503
Daidzein induces neuritogenesis in DRG neuronal cultures.
Authors: Ying Et al.
J Biomed Sci 2012;19:80

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