TAT-SAMβA Peptide
Purity: ≥95%
Biological Activity
TAT-SAMβA Peptide is a selective antagonist of Mfn1-βIIPKC association. Comprises the cell permeable peptide TAT47-57, conjugated to βIIPKC624-632 by a Gly-Gly spacer. TAT-SAMβA Peptide reduces mitochondrial fragmentation and stress-induced death in cultured cardiomyocytes. In rats with heart failure, TAT-SAMβA Peptide restores mitochondrial morphology, bioenergetics, and redox balance, which leads to improvement in cardiac contractility.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
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