Home / TGF-beta / TGF-beta Pan Specific Antibody

TGF-beta Pan Specific Antibody

Catalog #: AB-100-NA
56 Citations 3 Reviews Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
AB-100-NA
TGF-beta Pan Specific in Human Prostate Tissue.
2 Images
Product Details
Citations (56)
FAQs
Supplemental Products
Reviews (3)
Summary Data Examples Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

TGF-beta Pan Specific Antibody Summary

Specificity
Detects TGF-beta 1, TGF-beta 1.2, TGF-beta 2, TGF-beta 3, and TGF-beta 5 in direct ELISAs and Western blots.
Source
Polyclonal Rabbit IgG
Purification
Protein A or G purified
Immunogen
Recombinant human TGF‑ beta 1, porcine platelet-derived TGF‑ beta 1.2, porcine platelet-derived TGF‑ beta 2, and recombinant amphibian TGF‑ beta 5
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Endotoxin Level
<0.10 EU per 1 μg of the antibody by the LAL method.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Western Blot
1 µg/mL
Recombinant Human TGF-beta 1 (Catalog # 240-B)
Recombinant Human TGF-beta 2 (Catalog # 302-B2)
Recombinant Human TGF-beta 1.2 (Catalog # 304-B3)
Recombinant Human TGF-beta 3 (Catalog # 243-B3)
Recombinant Amphibian TGF-beta 5 (Catalog # 245-B5)
under non-reducing conditions only
Immunohistochemistry
3-15 µg/mL
See below
Neutralization
Measured by its ability to neutralize TGF‑ beta 1 inhibition of IL‑4-dependent proliferation in the HT‑2 mouse T cell line. Tsang, M. et al. (1995) Cytokine 7:389. The Neutralization Dose (ND50) is approximately  1 µg/mL, 15 µg/mL, 4 µg/mL, and 1 µg/mL for Porcine TGF-beta 1.2, Porcine TGF-beta 2, Recombinant Chicken TGF-beta 3, and Recombinant Amphibian TGF-beta 5, respectively. The ND50 range for Porcine TGF-beta 1 is 5-30 µg/mL.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Immunohistochemistry TGF-beta Pan Specific antibody in Human Prostate Tissue by Immunohistochemistry (IHC-P). View Larger

TGF-beta Pan Specific in Human Prostate Tissue. TGF-beta was detected in immersion fixed paraffin-embedded sections of human prostate tissue using Rabbit Anti-TGF-beta Pan Specific Polyclonal Antibody (Catalog # AB-100-NA) at 3 µg/mL for 1 hour at room temperature followed by incubation with the Anti-Rabbit IgG VisUCyte™ HRP Polymer Antibody (Catalog # VC003). Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (Catalog # CTS013). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to cytoplasm in epitjhelial cells. View our protocol for IHC Staining with VisUCyte HRP Polymer Detection Reagents.

Neutralization TGF‑ beta 1 Inhibition of IL‑4-dependent Cell Proliferation and Neutralization by TGF‑ beta Antibody. View Larger

TGF‑ beta 1 Inhibition of IL‑4-dependent Cell Proliferation and Neutralization by TGF‑ beta Antibody. Porcine TGF-beta 1 (Catalog # 101-B1) inhibits Recombinant Mouse IL-4 (Catalog # 404-ML) induced proliferation in the HT-2 mouse T cell line in a dose-dependent manner (orange line). Inhibition of Recombinant Mouse IL-4 (7.5 ng/mL) activity elicited by Porcine TGF-beta 1 (1 ng/mL) is neutralized (green line) by increasing concentrations of TGF-beta Pan Specific Polyclonal Antibody (Catalog # AB-100-NA). The ND50range is 5-30 µg/mL.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Preparation and Storage

Reconstitution
Reconstitute at 1 mg/mL in sterile PBS.
Loading...
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: TGF-beta

TGF-beta 1 (transforming growth factor beta 1) is one of three closely related mammalian members of the large TGF-beta superfamily that share a characteristic cystine knot structure. TGF-beta 1, -2 and -3 are highly pleiotropic cytokines that are proposed to act as cellular switches that regulate processes such as immune function, proliferation and epithelial-mesenchymal transition. Each TGF-beta isoform has some non-redundant functions; for TGF-beta 1, mice with targeted deletion show defects in hematopoiesis and endothelial differentiation, and die of overwhelming inflammation. Human TGF-beta 1 cDNA encodes a 390 amino acid (aa) precursor that contains a 29 aa signal peptide and a 361 aa proprotein. A furin-like convertase processes the proprotein to generate an N-terminal 249 aa latency-associated peptide (LAP) and a C-terminal 112 aa mature TGF- beta 1. Disulfide-linked homodimers of LAP and TGF-beta 1 remain non-covalently associated after secretion, forming the small latent TGF-beta 1 complex. Covalent linkage of LAP to one of three latent TGF-beta binding proteins (LTBPs) creates a large latent complex that may interact with the extracellular matrix. TGF-beta is activated from latency by pathways that include actions of the protease plasmin, matrix metalloproteases, thrombospondin 1 and a subset of integrins. Mature human TGF-beta 1 shares 100% aa identity with pig, dog and cow TGF-beta 1, and 99% aa identity with mouse, rat and horse TGF-beta 1. It demonstrates cross-species activity. TGF-beta 1 signaling begins with high-affinity binding to a type II ser/thr kinase receptor termed TGF-beta RII. This receptor then phosphorylates and activates a second ser/thr kinase receptor, TGF-beta RI (also called activin receptor-like kinase (ALK) -5), or alternatively, ALK‑1. This complex phosphorylates and activates Smad proteins that regulate transcription. Contributions of the accessory receptors betaglycan (also known as TGF-beta RIII) and endoglin, or use of Smad-independent signaling pathways, allow for disparate actions observed in response to TGF-beta in different contexts.

Long Name
Transforming Growth Factor beta
Alternate Names
CED; DPD1; LAP; TGFB; TGFB1; TGFbeta; TGF-beta; transforming growth factor beta 1

Product Datasheets

You must select a language.

x
Product Datasheet
COA
SDS

Citations for TGF-beta Pan Specific Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

56 Citations: Showing 1 - 10
Filter your results:

Filter by:

  1. Expression of TGF-beta and MMP-2 in hereditary gingival fibromatosis epithelial cells. A possible contribution of the epithelium to its pathogenesis
    Authors: NM Kamal, MA Hamouda, N Abdelgawad
    Journal of oral biology and craniofacial research, 2022-08-14;12(5):617-622.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  2. Inhibition of miR-155 Promotes TGF-beta Mediated Suppression of HIV Release in the Cervical Epithelial Cells
    Authors: J Gokavi, S Sadawarte, A Shelke, U Kulkarni-K, M Thakar, V Saxena
    Viruses, 2021-11-12;13(11):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  3. TGF-&beta loaded exosome enhances ischemic wound healing in vitro and in vivo
    Authors: A Shi, J Li, X Qiu, M Sabbah, S Boroumand, TC Huang, C Zhao, A Terzic, A Behfar, SL Moran
    Theranostics, 2021-04-30;11(13):6616-6631.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  4. Effects of Tenascin C on the Integrity of Extracellular Matrix and Skin Aging
    Authors: YE Choi, MJ Song, M Hara, K Imanaka-Yo, DH Lee, JH Chung, ST Lee
    Int J Mol Sci, 2020-11-18;21(22):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  5. TGF-&beta in the Secretome of Irradiated Peripheral Blood Mononuclear Cells Supports In Vitro Osteoclastogenesis
    Authors: L Panahipour, Z Kargarpour, M Laggner, M Mildner, HJ Ankersmit, R Gruber
    Int J Mol Sci, 2020-11-13;21(22):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Neutralization
  6. Roxatidine inhibits fibrosis by inhibiting NF?kappaB and MAPK signaling in macrophages sensing breast implant surface materials
    Authors: L Ji, T Wang, L Tian, H Song, M Gao
    Mol Med Rep, 2019-11-12;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Neutralization
  7. Cervical cancer cells produce TGF-?1 through the CD73-adenosine pathway and maintain CD73 expression through the autocrine activity of TGF-?1
    Authors: R García-Roc, A Monroy-Gar, J Hernández-, B Weiss-Stei, V Gutiérrez-, M Del Carmen, LR Ávila-Ibar, CA Don-López, DB Torres-Pin, M de Lourdes
    Cytokine, 2018-10-06;118(0):71-79.
    Species: Human
    Sample Types: Cell Culture Supernates
    Applications: Neutralization
  8. DNA methylation affects metastasis of renal cancer and is associated with TGF-?/RUNX3 inhibition
    Authors: J Zheng, Y Mei, P Xiang, G Zhai, N Zhao, C Xu, M Liu, Z Pan, K Tang, D Jia
    Cancer Cell Int., 2018-04-10;18(0):56.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  9. Cardiac macrophages promote diastolic dysfunction
    Authors: M Hulsmans, HB Sager, JD Roh, M Valero-Muñ, NE Houstis, Y Iwamoto, Y Sun, RM Wilson, G Wojtkiewic, B Tricot, MT Osborne, J Hung, C Vinegoni, K Naxerova, DE Sosnovik, MR Zile, AD Bradshaw, R Liao, A Tawakol, R Weissleder, A Rosenzweig, FK Swirski, F Sam, M Nahrendorf
    J. Exp. Med., 2018-01-16;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  10. The IL-2/Anti-IL-2 Complex Attenuates Cardiac Ischaemia-Reperfusion Injury Through Expansion of Regulatory T Cells
    Authors: J Xiao, K Yu, M Li, C Xiong, Y Wei, Q Zeng
    Cell. Physiol. Biochem., 2017-12-07;44(5):1810-1827.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Neutralization
  11. Naive CD4(+) T Cells Carrying a TLR2 Agonist Overcome TGF-beta-Mediated Tumor Immune Evasion.
    Authors: Ibrahim M, Scozzi D, Toth K, Ponti D, Kreisel D, Menna C, De Falco E, D'Andrilli A, Rendina E, Calogero A, Krupnick A, Gelman A
    J Immunol, 2017-12-06;200(2):847-856.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Neutralization
  12. TGF-? contamination of purified recombinant GDF15
    Authors: OE Olsen, A Skjærvik, BF Størdal, A Sundan, T Holien
    PLoS ONE, 2017-11-21;12(11):e0187349.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  13. Nonmyocyte ERK1/2 signaling contributes to load-induced cardiomyopathy in Marfan mice
    Authors: R Rouf, EG MacFarlane, E Takimoto, R Chaudhary, V Nagpal, PP Rainer, JG Bindman, EE Gerber, D Bedja, C Schiefer, KL Miller, G Zhu, L Myers, N Amat-Alarc, DI Lee, N Koitabashi, DP Judge, DA Kass, HC Dietz
    JCI Insight, 2017-08-03;2(15):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Neutralization
  14. Pulsed Electromagnetic Field Regulates MicroRNA 21 Expression to Activate TGF-? Signaling in Human Bone Marrow Stromal Cells to Enhance Osteoblast Differentiation
    Authors: N Selvamurug, Z He, D Rifkin, B Dabovic, NC Partridge
    Stem Cells Int, 2017-04-23;2017(0):2450327.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  15. ST2/IL-33-Dependent Microglial Response Limits Acute Ischemic Brain Injury
    Authors: Y Yang, H Liu, H Zhang, Q Ye, J Wang, B Yang, L Mao, W Zhu, RK Leak, B Xiao, B Lu, J Chen, X Hu
    J. Neurosci., 2017-04-07;0(0):.
    Species: Mouse, Rat
    Sample Types: Whole Cells
    Applications: Neutralization
  16. Endoplasmic Reticulum Oxidative Stress Triggers Tgf-Beta-Dependent Muscle Dysfunction by Accelerating Ascorbic Acid Turnover
    Authors: D Pozzer, M Favellato, M Bolis, RW Invernizzi, F Solagna, B Blaauw, E Zito
    Sci Rep, 2017-01-20;7(0):40993.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Neutralization
  17. MXRA5 is a TGF-?1-regulated human protein with anti-inflammatory and anti-fibrotic properties
    J Cell Mol Med, 2016-09-06;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  18. Lymphatic vessels regulate immune microenvironments in human and murine melanoma
    J Clin Invest, 2016-08-15;0(0):.
    Species: Human
    Sample Types: Tissue Homogenates
    Applications: Western Blot
  19. TGF-? Neutralization Enhances AngII-Induced Aortic Rupture and Aneurysm in Both Thoracic and Abdominal Regions
    Authors: X Chen, DL Rateri, DA Howatt, A Balakrishn, JJ Moorleghen, LA Cassis, A Daugherty
    PLoS ONE, 2016-04-22;11(4):e0153811.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Neutralization
  20. Osmotic Induction of Angiogenic Growth Factor Expression in Human Retinal Pigment Epithelial Cells.
    Authors: Veltmann M, Hollborn M, Reichenbach A, Wiedemann P, Kohen L, Bringmann A
    PLoS ONE, 2016-01-22;11(1):e0147312.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  21. Stearoyl-CoA desaturase 1 and paracrine diffusible signals have a major role in the promotion of breast cancer cell migration induced by cancer-associated fibroblasts.
    Authors: Angelucci C, Maulucci G, Colabianchi A, Iacopino F, D'Alessio A, Maiorana A, Palmieri V, Papi M, De Spirito M, Di Leone A, Masetti R, Sica G
    Br J Cancer, 2015-04-16;112(10):1675-86.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  22. Bmi1 limits dilated cardiomyopathy and heart failure by inhibiting cardiac senescence.
    Authors: Gonzalez-Valdes I, Hidalgo I, Bujarrabal A, Lara-Pezzi E, Padron-Barthe L, Garcia-Pavia P, Gomez-del Arco P, Redondo J, Ruiz-Cabello J, Jimenez-Borreguero L, Enriquez J, de la Pompa J, Hidalgo A, Gonzalez S
    Nat Commun, 2015-03-09;6(0):6473.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Neutralization
  23. Identification of genetic loci that control mammary tumor susceptibility through the host microenvironment.
    Authors: Zhang P, Lo A, Huang Y, Huang G, Liang G, Mott J, Karpen G, Blakely E, Bissell M, Barcellos-Hoff M, Snijders A, Mao J
    Sci Rep, 2015-03-09;5(0):8919.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Blocking
  24. CD4(+)Foxp3(+) Tregs protect against innate immune cell-mediated fulminant hepatitis in mice.
    Authors: Hou X, Song J, Su J, Huang D, Gao W, Yan J, Shen J
    Mol Immunol, 2014-10-12;63(2):420-7.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Neutralization
  25. Emdogain-regulated gene expression in palatal fibroblasts requires TGF-betaRI kinase signaling.
    Authors: Stahli A, Bosshardt D, Sculean A, Gruber R
    PLoS ONE, 2014-09-08;9(9):e105672.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  26. Platelets provoke distinct dynamics of immune responses by differentially regulating CD4+ T-cell proliferation.
    Authors: Zhu L, Huang Z, Stalesen R, Hansson G, Li N
    J Thromb Haemost, 2014-06-27;12(7):1156-65.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  27. Expression of versican V3 by arterial smooth muscle cells alters tumor growth factor beta (TGFbeta)-, epidermal growth factor (EGF)-, and nuclear factor kappaB (NFkappaB)-dependent signaling pathways, creating a microenvironment that resists monocyte adhesion.
    Authors: Kang I, Yoon D, Braun K, Wight T
    J Biol Chem, 2014-04-09;289(22):15393-404.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Neutralization
  28. Loss of Dab2 expression in breast cancer cells impairs their ability to deplete TGF-beta and induce Tregs development via TGF-beta.
    Authors: Xu S, Zhu J, Wu Z
    PLoS ONE, 2014-03-17;9(3):e91709.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  29. Autophagy fosters myofibroblast differentiation through MTORC2 activation and downstream upregulation of CTGF.
    Authors: Bernard M, Dieude M, Yang B, Hamelin K, Underwood K, Hebert M
    Autophagy, 2014-01-01;10(12):2193-207.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  30. IL-2/anti-IL-2 complex attenuates renal ischemia-reperfusion injury through expansion of regulatory T cells.
    Authors: Kim M, Koo T, Yan J, Lee E, Han K, Jeong J, Ro H, Kim B, Jo S, Oh K, Surh C, Ahn C, Yang J
    J Am Soc Nephrol, 2013-07-05;24(10):1529-36.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Neutralization
  31. Human prostate tumor antigen-specific CD8+ regulatory T cells are inhibited by CTLA-4 or IL-35 blockade.
    Authors: Olson B, Jankowska-Gan E, Becker J, Vignali D, Burlingham W, McNeel D
    J Immunol, 2012-11-14;189(12):5590-601.
    Species: Human
    Sample Types: In Vivo
    Applications: Bioassay
  32. Toll-like Receptor 2 (TLR2), Transforming Growth Factor-beta, Hyaluronan (HA), and Receptor for HA-mediated Motility (RHAMM) Are Required for Surfactant Protein A-stimulated Macrophage Chemotaxis.
    Authors: Foley J, Lam D, Jiang H, Liao J, Cheong N, McDevitt T, Zaman A, Wright J, Savani R
    J Biol Chem, 2012-09-04;287(44):37406-19.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Neutralization
  33. Transglutaminase 2 cross-linking activity is linked to invadopodia formation and cartilage breakdown in arthritis.
    Authors: Lauzier A, Charbonneau M, Paquette M, Harper K, Dubois CM
    Arthritis Res. Ther., 2012-07-04;14(4):R159.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  34. Nonmyelinating Schwann cells maintain hematopoietic stem cell hibernation in the bone marrow niche.
    Authors: Yamazaki S, Ema H, Karlsson G, Yamaguchi T, Miyoshi H, Shioda S, Taketo MM, Karlsson S, Iwama A, Nakauchi H
    Cell, 2011-11-23;147(5):1146-58.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  35. Calpain mediates pulmonary vascular remodeling in rodent models of pulmonary hypertension, and its inhibition attenuates pathologic features of disease.
    Authors: Ma W, Han W, Greer PA, Tuder RM, Toque HA, Wang KK, Caldwell RW, Su Y
    J. Clin. Invest., 2011-10-17;121(11):4548-66.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Neutralization
  36. IL-33 induces IL-9 production in human CD4+ T cells and basophils.
    Authors: Blom L, Poulsen BC, Jensen BM, Hansen A, Poulsen LK
    PLoS ONE, 2011-07-06;6(7):e21695.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  37. The sensing of environmental stimuli by follicular dendritic cells promotes immunoglobulin A generation in the gut.
    Authors: Suzuki K, Maruya M, Kawamoto S
    Immunity, 2010-07-23;33(1):71-83.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Neutralization
  38. Interferon-gamma and the interferon-inducible chemokine CXCL10 protect against aneurysm formation and rupture.
    Authors: King VL, Lin AY, Kristo F, Anderson TJ, Ahluwalia N, Hardy GJ, Owens AP, Howatt DA, Shen D, Tager AM, Luster AD, Daugherty A, Gerszten RE
    Circulation, 2009-01-12;119(3):426-35.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Neutralization
  39. Direct and indirect impairment of human dendritic cell function by virulent Francisella tularensis Schu S4.
    Authors: Chase JC, Celli J, Bosio CM
    Infect. Immun., 2008-11-03;77(1):180-95.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  40. Molecular mechanisms of TGFbeta receptor-triggered signaling cascades rapidly induced by the calcineurin inhibitors cyclosporin A and FK506.
    Authors: Akool el-S, Doller A, Babelova A, Tsalastra W, Moreth K, Schaefer L, Pfeilschifter J, Eberhardt W
    J. Immunol., 2008-08-15;181(4):2831-45.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Neutralization
  41. Local administration of interleukin-11 ameliorates intestinal radiation injury in rats.
    Authors: Boerma M, Wang J, Burnett AF, Santin AD, Roman JJ, Hauer-Jensen M
    Cancer Res., 2007-10-01;67(19):9501-6.
    Species: Rat
    Sample Types: Whole Cells
    Applications: ICC
  42. Transforming growth factor-beta1 suppresses airway hyperresponsiveness in allergic airway disease.
    Authors: Alcorn JF, Rinaldi LM, Jaffe EF, van Loon M, Bates JH, Janssen-Heininger YM, Irvin CG
    Am. J. Respir. Crit. Care Med., 2007-08-29;176(10):974-82.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Neutralization
  43. Collagen I promotes epithelial-to-mesenchymal transition in lung cancer cells via transforming growth factor-beta signaling.
    Authors: Shintani Y, Maeda M, Chaika N, Johnson KR, Wheelock MJ
    Am. J. Respir. Cell Mol. Biol., 2007-08-02;38(1):95-104.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  44. Advanced glycation end products decrease mesangial cell MMP-7: a role in matrix accumulation in diabetic nephropathy?
    Authors: McLennan SV, Kelly DJ, Schache M, Waltham M, Dy V, Langham RG, Yue DK, Gilbert RE
    Kidney Int., 2007-06-06;72(4):481-8.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  45. Angiotensin II type 1 receptor blockade attenuates TGF-beta-induced failure of muscle regeneration in multiple myopathic states.
    Authors: Cohn RD, van Erp C, Habashi JP, Soleimani AA, Klein EC, Lisi MT, Gamradt M, ap Rhys CM, Holm TM, Loeys BL, Ramirez F, Judge DP, Ward CW, Dietz HC
    Nat. Med., 2007-01-21;13(2):204-10.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Neutralization
  46. Increase in transforming growth factor-beta in the brain during infection is related to fever, not depression of spontaneous motor activity.
    Authors: Matsumura S, Shibakusa T, Fujikawa T, Yamada H, Inoue K, Fushiki T
    Neuroscience, 2006-12-06;144(3):1133-40.
    Species: Rat
    Sample Types: CSF
    Applications: Neutralization
  47. Uptake of host cell transforming growth factor-beta by Trypanosoma cruzi amastigotes in cardiomyocytes: potential role in parasite cycle completion.
    Authors: Waghabi MC, Keramidas M, Bailly S, Degrave W, Mendonca-Lima L, Soeiro Mde N, Meirelles Mde N, Paciornik S, Araujo-Jorge TC, Feige JJ
    Am. J. Pathol., 2005-10-01;167(4):993-1003.
    Species: Mouse
    Sample Types: Whole Cells, Whole Tissue
    Applications: Electron Microscopy, ICC, IHC-P, Neutralization
  48. Nitric oxide induces TIMP-1 expression by activating the transforming growth factor beta-Smad signaling pathway.
    Authors: Akool el-S, Doller A, Muller R, Gutwein P, Xin C, Huwiler A, Pfeilschifter J, Eberhardt W
    J. Biol. Chem., 2005-09-23;280(47):39403-16.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Neutralization
  49. Thrombospondin plays a vital role in the immune privilege of the eye.
    Authors: Zamiri P, Masli S, Kitaichi N, Taylor AW, Streilein JW
    Invest. Ophthalmol. Vis. Sci., 2005-03-01;46(3):908-19.
    Species: Mink, Mouse
    Sample Types: Whole Cells
    Applications: Neutralization
  50. Neuronal TGF-beta1 mediates IL-9/mast cell interaction and exacerbates excitotoxicity in newborn mice.
    Authors: Mesples B, Fontaine RH, Lelievre V, Launay JM, Gressens P
    Neurobiol. Dis., 2005-02-01;18(1):193-205.
    Species: Mouse
    Sample Types: Tissue Homogenates
    Applications: Western Blot
  51. Immunoneutralization of growth differentiation factor 9 reveals it partially accounts for mouse oocyte mitogenic activity.
    Authors: Gilchrist RB, Ritter LJ, Cranfield M, Jeffery LA, Amato F, Scott SJ, Myllymaa S, Kaivo-Oja N, Lankinen H, Mottershead DG, Groome NP, Ritvos O
    Biol. Reprod., 2004-05-05;71(3):732-9.
    Species: Bovine, Mouse
    Sample Types: Whole Cells
    Applications: Neutralization
  52. Natural and induced CD4+CD25+ cells educate CD4+CD25- cells to develop suppressive activity: the role of IL-2, TGF-beta, and IL-10.
    Authors: Zheng SG, Wang JH, Gray JD, Soucier H, Horwitz DA
    J. Immunol., 2004-05-01;172(9):5213-21.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  53. Metastable tolerance to rhesus monkey renal transplants is correlated with allograft TGF-beta 1+CD4+ T regulatory cell infiltrates.
    Authors: Torrealba JR, Katayama M, Fechner JH, Jankowska-Gan E, Kusaka S, Schultz JM, Hu H, Hamawy MM, Jonker M, Wubben J, Doxiadis G, Bontrop R, Burlingham WJ, Knechtle SJ
    J. Immunol., 2004-05-01;172(9):5753-64.
    Species: Primate - Macaca mulatta (Rhesus Macaque)
    Sample Types: Whole Cells
    Applications: Neutralization
  54. Effect of weightbearing on bone formation during distraction osteogenesis.
    Authors: Leung KS, Cheung WH, Yeung HY, Lee KM, Fung KP
    Clin. Orthop. Relat. Res., 2004-02-01;0(419):251-7.
    Species: Goat
    Sample Types: Whole Tissue
    Applications: IHC-P
  55. Connective tissue growth factor and its correlation to other growth factors in experimental granulation tissue.
    Authors: Inkinen K, Wolff H, Lindroos P, Ahonen J
    Connect. Tissue Res., 2003-01-01;44(1):19-29.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC-P
  56. Estrogen inhibition of PTH-stimulated osteoclast formation and attachment in vitro: involvement of both PKA and PKC.
    Authors: Liu BY, 2019, Wu PW, Bringhurst FR, Wang JT
    141-147, 2002-02-01;143(2):627-35.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Neutralization

FAQs

  1. Does TGF-beta Pan Specific Antibody, catalog # AB-100-NA, recognize active or latent TGF-beta (LAP)?

    • This antibody recognizes mature (active) TGF-beta. We have not tested for cross-reactivity to LAP (catalog # 246-LP) in our neutralization assay. Some cross-reactivity to latent TGF-beta may also be observed in western blot.

View all Antibody FAQs
Loading...

Reviews for TGF-beta Pan Specific Antibody

Average Rating: 4.3 (Based on 3 Reviews)

5 Star
33.33%
4 Star
66.67%
3 Star
0%
2 Star
0%
1 Star
0%

Have you used TGF-beta Pan Specific Antibody?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Filter by:


TGF-beta Pan Specific Antibody
By Tina Yuan on 11/23/2020
Application: IHC Sample Tested: mouse oral tissue Species: Mouse
Immunohistochemistry TGF-beta Pan Specific Antibody AB-100-NA
TGF-beta Pan Specific Antibody
By Anonymous on 03/23/2018
Application: Flow Sample Tested: Blood mononuclear cells (PBMCs) Species: Human
TGF-beta Pan Specific Antibody
By Anonymous on 06/06/2017
Application: B/N Sample Tested: Peritoneal macrophages Species: Mouse